Omega-3 fatty acids and airway hyperresponsiveness in asthma

Journal of Alternative and Complementary Medicine

Volumn 10, Issue 6, 2004, Pages 1067-1075

  Mickleborough, Timothy D ^a   Ionescu, Alina A ^b   Rundell, Kenneth W ^c  

^a INDIANA UNIVERSITY   (United States)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c MARYWOOD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; FISH OIL; ICOSAPENTAENOIC ACID; LEUKOTRIENE; LINOLEIC ACID; LINOLENIC ACID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PROSTANOID;

AIRWAY OBSTRUCTION; ALTERNATIVE MEDICINE; ASTHMA; ATHLETE; BRONCHOSPASM; BRONCHUS HYPERREACTIVITY; CLINICAL TRIAL; DIET SUPPLEMENTATION; DIET THERAPY; DISEASE EXACERBATION; DISEASE SEVERITY; DRUG EFFICACY; EXERCISE; HUMAN; INFLAMMATION; PHYSICAL ACTIVITY; PRIORITY JOURNAL; REVIEW; SYMPTOMATOLOGY;

AIRWAY RESISTANCE; ASTHMA, EXERCISE-INDUCED; BRONCHIAL HYPERREACTIVITY; BRONCHOCONSTRICTION; BRONCHODILATOR AGENTS; FATTY ACIDS, OMEGA-3; HUMANS; RESPIRATORY FUNCTION TESTS; SPORTS;

EID: 13144272339     PISSN: 10755535     EISSN: None     Source Type: Journal    
DOI: 10.1089/acm.2004.10.1067     Document Type: Review

References (76)

1. American Lung Association. Epidemiology and Statistics Unit Research and Scientific Affairs. Trends in Asthma Morbidity and Mortality. New York: American Lung Association, 2003.
2. Anderson HR. Is the prevalence of asthma changing? Arch Dis Child 1989;64:172-175.
3. Anonymous. Standardization of spirometry - 1994 update. Statement of the American Thoracic Society. Am J Respir Crit Care Med 1995;152:1107-1136.
4. Arm JP, Horton CE, Mencia-Huerta JM, House F, Eiser NM, Clark TJ, Spur BW, Lee TH. Effect of dietary supplementation with fish oil lipids on mild asthma. Thorax 1988;43:84-92.
5. Arm JP, Horton CE, Spur BW, Mencia-Huerta JM, Lee TH. The effects of dietary supplementation with fish oil lipids on the airways response to inhaled allergen in bronchial asthma. Am Rev Respir Dis 1989;139:1395-1400.
6. Baker JC, Ayres JG. Diet and asthma. Respir Med 2000; 94:925-934.
7. Barbato A, Turato G, Baraldo S, Bazzan E, Calabrese F, Tura M, Zuin R, Beghe B, Maestrelli P, Fabbri LM, Saetta M. Airway inflammation in childhood asthma. Am J Respir Crit Care Med 2003;168:798-803.
8. Bisgaard H. Long-acting beta(2)-agonists in management of childhood asthma: A critical review of the literature. Pediatr Pulmonol 2003;29:221-234.
9. Black PN, Sharpe S. Dietary fat and asthma: Is there a connection? Eur Respir J 1997;10:6-12.
10. Bodner C, Godden D, Brown K, Little J, Ross S, Seaton A. Antioxidant intake and adult-onset wheeze: a case-control study. Aberdeen WHEASE Study Group. Eur Respir J 1999;13:22-30.
11. Broadfield EC, McKeever TM, Whitehurst A, Lewis SA, Lawson N, Britton J, Fogarty A. A case-control study of dietary and erythrocyte membrane fatty acids in asthma. Clin Exp Allergy 2004;34:1232-1236.
12. Broughton KS, Johnson CS, Pace BK, Liebman M, Kleppinger KM. Reduced asthma symptoms with ω-3 fatty acid ingestion are related to 5-series leukotriene production. Am J Clin Nutr 1997;65:1011-1017.
13. Bureau F, Delhalle S, Bonizzi G, Fievez L, Dogne S, Kirschvink N, Vanderplasschen A, Merville M-P, Bours V, Lekeux P. Mechanisms of persistent NF-κ B Activity in the bronchi of an animal model of asthma. J Immunonl 2000;165:5822-5830.
14. Burney PG, Chinn S, Rona RJ. Has the prevalence of asthma increased in children? Evidence from the national study of health and growth 1973-86. BMJ 1990;300:1306-1310.
15. Chang CC, Phinney SD, Halpern GM, Gershwin ME. Asthma mortality: Another opinion - is it a matter of life and . . . bread? J Asthma 1993;30:93-103.
16. Crapo RD, Casaburi R, Coates AL, Enright PL, Hankinson JL, Irvin CG, MacIntyre NR, McKay RT, Wanger JS, Anderson SD, Cockcroft DW, Fish JE, Sterle PJ. Guidelines for Methacholine and Exercise Challenge Testing-1999. This official statement of the American Thoracic Society was adopted by the ATS board of directors, Am J Respir Crit Care Med 2000;161:309-329.
17. De Caterina R, Zampolli A. From asthma to atherosclerosis - 5-Lipoxygenase, leukotrienes, and inflammation. N Engl J Med 2004;350:4-7.
18. Denny SI, Thompson RL, Margetts BM. Dietary factors in the pathogenesis of asthma and chronic obstructive pulmonary disease. Curr Allergy Asthma Rep 2003;3:130-136.
19. Devereux G, Seaton A. Why don't we give chest patients dietary advice? Thorax 2001;56(Suppl 2):ii15-22.
20. Dry J, Vincent D. Effect of a fish oil diet on asthma: Results of a 1-year double-blind study. Int Arch Allergy Appl Immunol 1991;95:156-157.
21. Emelyanov A, Fedoseev G, Krasnoschekova O, Abulimity A, Trendeleva T, Barnes PJ. Treatment of asthma with lipid extract of New Zealand green-lipped mussel: A randomised clinical trial. Eur Respir J 2002;20:596-600.
22. Endres S, Ghorbani R, Kelley VE, Georgilis K, Lonnemann G, van der Meer JW, Cannon JG, Rogers TS, Klempner MS, Weber PC, et al. The effect of dietary supplementation with ω-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells. N Engl J Med 1989;320:265-271.
23. Fogarty A, Britton J. The role of diet in the aetiology of asthma. Clin Exp Allergy 2000;30:615-627.
24. Gadek JE, DeMichele SJ, Karlstad MD, Pacht ER, Donahoe M, Albertson TE, Van Hoozen C, Wennberg AK, Nelson JL, Noursalehi M. Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in patients with acute respiratory distress syndrome. Enteral Nutrition in ARDS Study Group. Crit Care Med 1999;27:1409-1420.
25. Gagliardo R, Chanez P, Mathieu M, Bruno A, Costanzo G, Gougat C, Vachier I, Bousquet J, Bonsignore G, Vignola AM. Persistent activation of nuclear factor-κ B signaling pathway in severe uncontrolled asthma. Am J Respir Crit Care Med 2003;168:1190-1198.
26. Haby MM, Peat JK, Marks GB, Woolcock AJ, Leeder SR. Asthma in preschool children: prevalence and risk factors. Thorax 2001;56:589-595.
27. Hackman RM, Stern JS, Gershwin ME. Complementary and alternative medicine and asthma. Clin Rev Allergy Immunol 1996;14:321-336.
28. Halfon N, Newacheck PW. Trends in the hospitalization for acute childhood asthma, 1970-84. Am J Public Health 1986;76:1308-1311.
29. Hancox RJ, Subbarao P, Kamada D, Watson RM, Hargreave FE, Inman MD. Beta2-agonist tolerance and exercise-induced bronchospasm. Am J Respir Crit Care Med 2002;165:1068-1070.
30. Hart LA, Krishnan VL, Adcock IM, Barnes PJ, Chung KF. Activation and localization of transcription factor, nuclear factor-κ B, asthma. Am J Respir Crit Care Med 1998;158:1585-1592.
31. Hart L, Lim S, Adcock I, Barnes PJ, Fan Chung K. Effects of inhaled corticosteroid therapy on expression and DNA-binding activity of nuclear factor-κ B in asthma. Am J Respir Crit Care Med 2000;161:224-231.
32. Heller A, Koch T, Schmeck J, van Ackern K. Lipid mediators in inflammatory disorders. Drugs 1998;55:487-496.
33. Hodge L, Salome CM, Hughes JM, Liu-Brennan D, Rimmer J, Allman M, Pang D, Armour C, Woolcock AJ. Effect of dietary intake of omega-3 and omega-6 fatty acids on severity of asthma in children. Eur Respir J 1998;11:361-365.
34. Hodge L, Salome CM, Peat JK, Haby MM, Xuan W, Woolcock AJ. Consumption of oily fish and childhood asthma risk. Med J Aust 1996;164:137-140.
35. Hwang D. Fatty acids and immune responses - a new perspective in searching for clues to mechanism. Annu Rev Nutr 2000;20:431-456.
36. Jump DB. The biochemistry of ω-3 polyunsaturated fatty acids. J Biol Chem 2002;277:8755-8758.
37. Kelley DS. Modulation of human immune and inflammatory responses by dietary fatty acids. Nutrition 2001;17:669-673.
38. Kirsch CM, Payan DG, Wong MY, Dohlman JG, Blake VA, Petri MA, Offenberger J, Goetzl EJ, Gold WM. Effect of eicosapentaenoic acid in asthma. Clin Allergy 1988;18:177-187.
39. Klaukka T, Peura S, Martikainen J. Why has the utilization of antiasthmatics increased in Finland? J Clin Epidemiol 1991;44:859-863.
40. Lee JY, Plakidas A, Lee WH, Heikkinen A, Chanmugam P, Bray G, Hwang DH. Differential modulation of Toll-like receptors by fatty acids: Preferential inhibition by ω-3 polyunsaturated fatty acids. J Lipid Res 2003;44:479-486.
41. Lee JY, Sohn KH, Rhee SH, Hwang D. Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. J Biol Chem 2001;276:16683-16689.
42. Lee TH, Hoover RL, Williams JD, Sperling RI, Ravalese J, 3rd, Spur BW, Robinson DR, Corey EJ, Lewis RA, Austen KF. Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leukotriene generation and neutrophil function. N Engl J Med 1985;312:1217-1224.
43. Liu G, Bibus DM, Bode AM, Ma WY, Holman RT, Dong Z. Omega 3 but not omega 6 fatty acids inhibit AP-1 activity and cell transformation in JB6 cells. Proc Natl Acad Sci U S A 2001;98:7510-7515.
44. Lo CJ, Chiu KC, Fu M, Lo R, Helton S. Fish oil decreases macrophage tumor necrosis factor gene transcription by altering the NF kappa B activity. J Surg Res 1999;82:216-221.
45. Masoli M, Fabian D, Holt S, Beasley R. The global burden of asthma: Executive summary of the GINA Dissemination Committee Report. Allergy 2004;59:469-478.
46. Masuev KA. The effect of polyunsaturated fatty acids of the omega-3 class on the late phase of the allergic reaction in bronchial asthma patients. Ter Arkh 1997a;69:31-33.
47. Masuev KA. The effect of polyunsaturated fatty acids on the biochemical indices of bronchial asthma patients. Ter Arkh 1997b;69:33-35.
48. McDonald CF, Vecchie L, Pierce RJ, Strauss BJG. Effect of fish-oil derived omega-3 fatty acid supplements on asthma control. Aust N Z J Med 1990;20:526.
49. McKeever TM, Britton J. Pulmonary pespective: Diet and asthma. Am J Respir Crit Care Med 200405-611PP.
50. Mickleborough T, Gotshall R. Dietary components with demonstrated effectiveness in decreasing the severity of exercise-induced asthma. Sports Med 2003;33:671-681.
51. Mickleborough TD, Murray RL, Ionescu AA, Lindley MR. Fish oil supplementation reduces severity of exercise-induced bronchoconstriction in elite athletes. Am J Respir Crit Care Med 2003;168:1181-1189.
52. Molvig J, Pociot F, Worsaae H, Wogensen LD, Baek L, Christensen P, Mandrup-Poulsen T, Andersen K, Madsen P, Dyerberg J, et al. Dietary supplementation with omega-3-polyunsaturated fatty acids decreases mononuclear cell proliferation and interleukin-1 beta content but not monokine secretion in healthy and insulin-dependent diabetic individuals. Scand J Immunol 1991;34:399-410.
53. Nafstad P, Nystad W, Magnus P, Jaakkola JJ. Asthma and allergic rhinitis at 4 years of age in relation to fish consumption in infancy. J Asthma 2003;40:343-348.
54. Nagakura T, Matsuda S, Shichijyo K, Sugimoto H, Hata K. Dietary supplementation with fish oil rich in omega-3 polyunsaturated fatty acids in children with bronchial asthma. Eur Respir J 2000;16:861-865.
55. National Heart, Lung and Blood Institute. Morbidity and Mortality: 2002 Chart Book on Cardiovascular, Lung and Blood Diseases. Bethesda, MD: National Heart, Lung, Blood Institute, National Institutes of Health, 2002.
56. Novak TE, Babcock TA, Jho DH, Helton WS, Espat NJ. NF-kappa B inhibition by omega-3 fatty acids modulates LPS-stimulated macrophage TNF-alpha transcription. Am J Physiol Lung Cell Mol Physiol 2003;284:L84-L89.
57. Oddy WH, de Klerk NH, Kendall GE, Mihrshahi S, Peat JK. Ratio of omega-6 to omega-3 fatty acids and childhood asthma. J Asthma 2004;41:319-326.
58. Okamoto M, Mitsunobu F, Ashida K, Mifune T, Hosaki Y, Tsugeno H, Harada S, Tanizaki Y. Effects of dietary supplementation with ω-3 fatty acids compared with ω-6 fatty acids on bronchial asthma. Intern Med 2000a;39:107-111.
59. Okamoto M, Mitsunobu F, Ashida K, Mifune T, Hosaki Y, Tsugeno H, Harada S, Tanizaki Y, Kataoka M, Niiya K, Harada M. Effects of perilla seed oil supplementation on leukotriene generation by leucocytes in patients with asthma associated with lipometabolism. Int Arch Allergy Immunol 2000b;122:137-142.
60. Fatal B, Luban R, Lomas D, Wareham N. Regular oily fish consumption is protective against symptomatic asthma. Thorax 2002;57:iii47 (S156).
61. Payan DG, Wong MY, Chernov-Rogan T, Valone FH, Pickett WC, Blake VA, Gold WM, Goetzl EJ. Alterations in human leukocyte function induced by ingestion of eicosapentaenoic acid. J Clin Immunol 1986;6:402-410.
62. Picado C, Castillo JA, Schinca N, Pujades M, Ordinas A, Coronas A, Agusti-Vidal A. Effects of a fish oil enriched diet on aspirin intolerant asthmatic patients: a pilot study. Thorax 1988;43:93-97.
63. Picado C, Deulofeu R, Lleonart R, Agusti M, Mullol J, Quinto L, Torra M. Dietary micronutrients/antioxidants and their relationship with bronchial asthma severity. Allergy 2001;56:43-49.
64. Romieu I, Trenga C. Diet and obstructive lung diseases. Epidemiol Rev 2001;23:268-287.
65. Rundell KW, Jenkinson DM. Exercise-induced bronchospasm in the elite athlete. Sports Med 2002;32:583-600.
66. Smit HA. Chronic obstructive pulmonary disease, asthma and protective effects of food intake: From hypothesis to evidence? Respir Res 2001;2:261-264.
67. Smit HA, Grievink L, Tabak C. Dietary influences on chronic obstructive lung disease and asthma: A review of the epidemiological evidence. Proc Nutr Soc 1999;58:309-319.
68. Stenius-Aarniala B, Aro A, Hakulinen A, Ahola I, Seppala E, Vapaatalo H. Evening primose oil and fish oil are ineffective as supplementary treatment of bronchial asthma. Ann Allergy 1989;62:534-537.
69. Strom K, Janzon L, Mattisson I, Rosberg HE, Arborelius M. Asthma but not smoking-related airflow limitation is associated with a high fat diet in men: Results from the population study "Men born in 1914," Malmo, Sweden. Monaldi Arch Chest Dis 1996;51:16-21.
70. Surette ME, Koumenis IL, Edens MB, Tramposch KM, Clayton B, Bowton D, Chilton FH. Inhibition of leukotriene biosynthesis by a novel dietary fatty acid formulation in patients with atopic asthma: A randomized, placebo-controlled, parallel-group, prospective trial. Clin Ther 2003;25:972-979.
71. Takemura Y, Sakurai Y, Honjo S, Tokimatsu A, Gibo M, Hara T, Kusakari A, Kugai N. The relationship between fish intake and the prevalence of asthma: the Tokorozawa childhood asthma and pollinosis study. Prev Med 2002;34:221-225.
72. Thien FC, Mencia-Huerta JM, Lee TH. Dietary fish oil effects on seasonal hay fever and asthma in pollen-sensitive subjects. Am Rev Respir Dis 1993;147:1138-1143.
73. Villani F, Comazzi R, De Maria P, Galimberti M. Effect of dietary supplementation with polyunsaturated fatty acids on bronchial hyperreactivity in subjects with seasonal asthma. Respiration 1998;65:265-269.
74. Woods RK, Raven JM, Walters EH, Abramson MJ, Thien FC. Fatty acid levels and risk of asthma in young adults. Thorax 2004;59:105-110.
75. Woods RK, Thien FC, Abramson MJ. Dietary marine fatty acids (fish oil) for asthma in adults and children. Cochrane Database Syst Rev 2003;2:CD001283.
76. Zhao S, Qi Y, Liu X, Jiang Q, Liu S, Jiang Y, Jiang Z. Activation of NK-kB in bronchial epithelial cells from children with asthma. Clin Med J 2001;114:909-911.