Inhibition of glutamate carboxypeptidase II (NAALADase) protects against dynorphin A-induced ischemic spinal cord injury in rats

European Journal of Pharmacology

Volumn 508, Issue 1-3, 2005, Pages 115-122

  Long, Joseph B ^a   Yourick, Debra L ^a   Slusher, Barbara S ^b   Robinson, Michael B ^c   Meyerhoff, James L ^a  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^b GUILFORD PHARMACEUTICALS INC   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

(glutamate carboxypeptidase II); (N acetylaspartylglutamate); (N acetylated linked acidic dipeptidase); (N methyl d aspartate); Dynorphin A; GCP II; NAAG; NAALADase; Neuroprotection; NMDA

Indexed keywords

2 (PHOSPHONOMETHYL)PENTANEDIOIC ACID; DYNORPHIN A; FURAZOLIDONE; GLUTAMATE CARBOXYPEPTIDASE II; GLUTAMIC ACID; GLUTARIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CEREBROSPINAL FLUID; CONTROLLED STUDY; DOSE RESPONSE; ENZYME INHIBITION; EXCITOTOXICITY; HISTOPATHOLOGY; ISCHEMIA; MALE; MOTOR ACTIVITY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; RAT; SPINAL CORD INJURY;

ANIMALS; ANTERIOR HORN CELLS; CELL COUNT; DOSE-RESPONSE RELATIONSHIP, DRUG; DYNORPHINS; GLUTAMATE CARBOXYPEPTIDASE II; GLUTAMIC ACID; ISCHEMIA; MALE; MOTOR ACTIVITY; ORGANOPHOSPHORUS COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; TIME FACTORS;

EID: 12844281342     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.12.008     Document Type: Article

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