Statistical coevolution analysis and molecular dynamics: Identification of amino acid pairs essential for catalysis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 4, 2005, Pages 994-999

  Estabrook, R August ^a   Luo, Jia ^a   Purdy, Matthew M ^a   Sharma, Vyas ^a   Weakliem, Paul ^a   Bruice, Thomas C ^a   Reich, Norbert O ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Anticorrelated motion; Correlated motion; M.Hhal; Statistical coupling analysis

Indexed keywords

AMINO ACID; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA METHYLTRANSFERASE;

ARTICLE; CATALYSIS; COEVOLUTION; ENZYME ACTIVE SITE; ENZYME SUBSTRATE COMPLEX; EPIGENETICS; MOLECULAR DYNAMICS; MUTATION; PRIORITY JOURNAL; PROTEIN ENGINEERING; STEREOCHEMISTRY;

BINDING SITES; CATALYSIS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; SITE-SPECIFIC DNA METHYLTRANSFERASE (CYTOSINE-SPECIFIC); STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 12844268072     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0409128102     Document Type: Article

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