Importance of correlated motions in forming highly reactive near attack conformations in catechol O-methyltransferase

Journal of the American Chemical Society

Volumn 120, Issue 48, 1998, Pages 12387-12394

  Lau, Edmond Y ^a   Bruice, Thomas C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL METHYLTRANSFERASE; DOPAMINE; NORADRENALIN;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME CONFORMATION; HYDROPHOBICITY; METHYLATION; MOLECULAR DYNAMICS; PROTEIN TERTIARY STRUCTURE; X RAY ANALYSIS;

EID: 0032501378     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9827447     Document Type: Article

References (4)

1. Cheng, X.; Kumar, S.; Postai, J.; Pflugrath, J. W.; Roberts, R. J. Cell 1993, 74, 299.
2. Labahn, J.; Granzin, J.; Schluckebier, G.; Robinson, D. P.; Jack, W. E.; Schildkraut, I.; Saenger, W. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 10957.
3. Vidgren, J.; Svendsson, L. A.; Liljas, A. Nature 1994, 368, 354.
4. Schluckebier, G.; O'Gara, M.; Saenger, W.; Cheng, X. J. Mol. Biol. 1995, 247, 16.