Influence of culture conditions on the N-glycosylation of a monoclonal antibody specific for recombinant hepatitis B surface antigen

Biotechnology and Applied Biochemistry

Volumn 41, Issue 1, 2005, Pages 67-76

  Cabrera, Gleysin ^a   Cremata, José A ^a   Valdés, Rodolfo ^a   García, Rossana ^a   González, Yanelys ^a   Montesino, Raquel ^a   Gómez, Hector ^a   González, Marcos ^a  

^a CENTER FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Cuba)

Author keywords

Hepatitis B surface antigen; Hybridoma; Monoclonal antibody; N glycan profiling; N glycosylation; Oligosaccharide

Indexed keywords

ANTIGENS; BIOTECHNOLOGY; CELL CULTURE; CELL MEMBRANES; DRUG PRODUCTS; PROTEINS;

GALACTOSYLATION; GLYCOSYLATION; PROTEIN SEQUENCES; SERUM;

MONOCLONAL ANTIBODIES;

4 AMINOBENZOIC ACID; 8 AMINO 1,3,6 NAPHTHALENETRISULFONIC ACID; GALACTOSE; GLYCAN DERIVATIVE; HEPATITIS B SURFACE ANTIGEN; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G2B ANTIBODY; MONOCLONAL ANTIBODY; TRISULFA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBODY AFFINITY; ANTIBODY SPECIFICITY; ANTIGEN ANTIBODY COMPLEX; ARTICLE; ASCITES; BIOTECHNOLOGICAL PROCEDURES; CELL HETEROGENEITY; CONTROLLED STUDY; DIAGNOSTIC VALUE; DIALYSIS MEMBRANE; GLYCOSYLATION; HEPATITIS B; HYBRIDOMA; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN MODIFICATION; PROTEIN PROCESSING; REPRODUCIBILITY;

ANTIBODIES, MONOCLONAL; CELL CULTURE TECHNIQUES; CELL LINE; GLYCOSYLATION; HEPATITIS B ANTIBODIES; HEPATITIS B SURFACE ANTIGENS; HUMANS; HYBRIDOMAS; PROTEIN ENGINEERING; PROTEIN PROCESSING, POST-TRANSLATIONAL;

ANIMALIA;

EID: 12544249310     PISSN: 08854513     EISSN: None     Source Type: Journal    
DOI: 10.1042/BA20040032     Document Type: Article

References (38)

1. Rademacher, T. W., Homans, S. W., Parekh, R. B. and Dwek, R. A. (1986) Biochem. Soc. Symp. 51, 131-148
2. Raju, T. S., Briggs, J. B., Borge, S. M. and Jones, A. J. S. (2000) Glycobiology 10, 477-486
3. Jefferis, R., Lund, J., Mizutani, H., Nakagawa, H., Kawazoe, Y., Arata, Y. and Takahashi, N. (1990) Biochem. J. 268, 529-537
4. Bergwerff, A. A., Stroop, C. J. M., Murray, B., Holtori, A., Pluschke, G., van Oostrum, J., Kamerlimg, J. P. and Vliegenthart, J. F. G. (1994) Ph.D. Thesis, Utrecht University, pp. 131-151
5. Parekh, R. B., Dwek, R. A., Sutton, B. J., Fernandez, D. L., Leung, A., Stanworth, D., Rademacher T. W., Mizuochi, T., Taniguchi, T., Matsuta, K. et al. (1985) Nature (London) 316, 452-457
6. Goochee, C. F., Gramer, M. J., Andersen, D. C., Bahr J. B. and Rasmussen, J. R. (1991) Biotechnology 9, 1347-1355
7. Jenkins, N., Parekh, R. B. and James, D. C. (1996) Nat. Biotechnol. 14, 975-981
8. Fernández de Cossío, M. E., Díaz, T, Galván, A., Valdés, R., Gonzalez, E., Ayala, M., Díaz, J., Bestagno, M., Burrone, O. and Gavilondo, J. (1997) J. Biotechnol. 56, 69-80
9. Pentón, E., Herrera, L., Muzio, V., Ramírez, V., García, A., Duarte, C., Ruiz, C., Izquierdo, M., Pérez, L., Fontirrochi, G. et al. (1992) Eur Pat. Appl., 480525
10. Fontirrochi, G., Dueñas, M., Fernández de Cossío, M. E., Fuentes, P., Mainet, D., Ayala, M., Gavilondo, J. V. and Duarte, C. A. (1993) Biotecnol. Aplic. 10, 24-30
11. Hendriksen, C. F. and Leeuw, W. (1998) Res. Immunol. 6, 529-560
12. Danielsson, A., Ljunglof, A. and Lindblom, H. (1988) J. Immunol. Methods 115, 79-88
13. Valdés, R., Ibarra, N., González, M., Alvarez, T., García, J., Llambias, R., Pérez, C., Quintero, O. and Fischer R. (2001) Cytotechnol 35, 145-154
14. Jackson, P. (1994) Methods Enzymol. 230, 250-265
15. Yuen, C.-T., Gee, C. and Jones, C. (2002) Biomed. Chromatogr 16, 247-254
16. Jackson, P. (1990) Biochem. J. 270, 705-713
17. Stack, R. J. and Sullivan, M. T. (1992) Glycobiology 2, 85-92
18. Jackson, P. (1994) Methods Enzymol. 230, 250-265
19. Quintero, O., Montesino, R. and Cremata, J. A. (1998) Anal. Biochem. 256, 23-32
20. Jefferis, R., Lund, J. and Pound, J. D. (1998) Immunol. Rev. 163, 50-76
21. Dwek, R. A., Lellouch, A. C. and Wormald, M. R. (1995) J. Anat. 187, 279-292
22. Boyd, P. N., Lines, A. C. and Patel, A. K. (1995) Mol. Immunol. 32, 1311-1318
23. Shields, R. L., Namenuk, A. K., Hong, K., Meng, Y. G., Rae, J., Briggs, J., Xie, D., Lai, J., Stadien, A., Li, B. et al. (2001) J. Biol. Chem. 276, 6591-6604
24. Lund, J., Takahashi, N., Pound, J. D., Goodall, M. and Jefferis, R. (1996) J. Immunol. 157, 4963-4969
25. Lund, J., Takahashi, N., Popplewell, A., Goodall, M., Pound, J. D., Tyler, R., King, D. J. and Jefferis, R. (2000) Eur J. Biochem. 267, 7246-7257
26. Lifely M. R., Hale, C., Boyce, S., Keen, M. J. and Phillips, J. (1995) Glycobiology 5, 813-822
27. Patel, T. P., Parekh, R. B., Moellering, B. J. and Prior C. P. (1992) Biochem. J. 285, 839-845
28. Maiorella, B. L., Winkelhake, J., Young, J., Noyer, B., Bauer, R., Hora, M., Andya, J., Thompson, J., Patel, T. and Parekh, R. (1993) Biotechnology 11, 387-392
29. Monica, T. J., Goochee, C. F. and Maiorella, B. L. (1993) Bio/Technology 11, 512-515
30. Lund, J., Takahashi, N., Nakagawa, H., Goodall, M., Bentley T, Hindley S. A., Tyler, R. and Jefferis, R. (1993) Mol. Immunol. 30, 741-748
31. Kumpel, B. M., Rademachen T. W., Rook, G. A. W., Williams, P. J. and Wilson, I. B. H. (1994) Hum. Antibodies Hybridomas 5, 143-151
32. Gawlitzek M., Ryll, T., Lofgren, J. and Sliwkowski, M. B. (2000) Biotechnol. Bioeng. 68, 637-646
33. Kunkel, J. P., Jan, D. C. H., Butler, M. and Jamieson, J. C. (2000) Biotechnol. Prog. 16, 462-470
34. Kunkel, J. P., Jan, D. C. H., Jamieson, J. C. and Butler, M. (1998) J. Biotechnol. 62, 55-71
35. Rademacher, T. W., Jones, R. H. V. and Williams, P. J. (1995) Adv. Exp. Med. Biol. 376, 193-204
36. Ramirez, N., Rodríguez, M., Ayala, M., Cremata, J. A., Pérez, M., Martinez, A., Linares, M., Hevia, Y., Paez, R., Valdés, R. et al. (2003) Biotechnol. Appl. Biochem. 38, 223-230
37. Jefferis, R. and Lund, J. (1997) Chem. Immunol. 65, 111-128
38. Malhotra, R., Wormald, M. R., Rudd, P. M., Fischer, P. B., Dwek, R. A. and Sim, R. B. (1995) Nat. Med. 1, 237-243