Expression and characterization of truncated forms of humanized L243 IgG1: Architectural features can influence synthesis of its oligosaccharide chains and affect superoxide production triggered through human Fcγ receptor I

European Journal of Biochemistry

Volumn 267, Issue 24, 2000, Pages 7246-7257

  Lund, John ^a   Takahashi, Noriko ^b   Popplewell, Andrew ^c   Goodall, Margaret ^a   Pound, John D ^a,d   Tyler, Ruth ^a   King, David J ^c,e   Jefferis, Royston ^a  

^a Medical School   (United Kingdom)

^b Mitsukan Group Co   (Japan)

^c UCB PHARMA   (Belgium)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e Coulter Pharmaceutical ^*  (United States)

Author keywords

Antibodies; Architecture; Fc receptors; Glycosylation; Superoxide

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; OLIGOSACCHARIDE; SUPEROXIDE; UNCLASSIFIED DRUG;

ALKYLATION; ANIMAL CELL; ANTIBODY PRODUCTION; ANTIBODY STRUCTURE; ARTICLE; CHO CELL; CONTROLLED STUDY; DISULFIDE BOND; GENE EXPRESSION SYSTEM; GLYCOSYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; REDUCTION; SENSITIZATION; SIALYLATION; STRUCTURE ACTIVITY RELATION;

EID: 0034532141     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01839.x     Document Type: Article

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