A potentially critical molecule in pathologic processes including neoplasia

American Journal of Clinical Pathology

Volumn 110, Issue 4, 1998, Pages 425-440

  Listinsky, Jay J ^b   Siegal, Gene P ^a   Listinsky, Catherine M ^b  

^a University of Alabama at Birmingham   (United States)

^b NONE

Author keywords

Cancer; Cell membrane; Fucose; Lewis antigen; Neoplasia; Nuclear magnetic resonance; Sugar

Indexed keywords

BLOOD GROUP ANTIGEN; FUCOSE; GALACTOSE; GLYCOLIPID; GLYCOPROTEIN; SIALIC ACID; LIGAND;

ANTIBODY SPECIFICITY; CELL ADHESION; CELL FUNCTION; EXTRACELLULAR MATRIX; FUCOSYLATION; INFLAMMATION; LIGAND BINDING; MALIGNANT NEOPLASTIC DISEASE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REVIEW; ANIMAL; CARBOHYDRATE ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; ISOMERISM; MOLECULAR GENETICS; PHYSIOLOGY;

ANIMALS; BLOOD GROUP ANTIGENS; CARBOHYDRATE SEQUENCE; FUCOSE; HUMANS; ISOMERISM; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA;

EID: 0032186306     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcp/110.4.425     Document Type: Review

References (192)

1. Mountford CE, Grossman G, Reid G, et al. Characterization of transformed cells and tumors by proton nuclear magnetic resonance spectroscopy. Cancer Res. 1982;42:2270-2276.
2. 2-filtered COSY experiment to identify the origin of slowly relaxing species in normal and malignant tissue. Magn Reson Med. 1988;7:463-471.
3. Lean CL, Mackinnon WB, Delikatny EJ, et al. Cell-surface fucosylation and magnetic resonance spectroscopy characterization of human malignant colorectal cells. Biochemistry. 1992;31:11095-11105.
4. 1H MRS: correlation with histopathology. Magn Reson Med. 1993;30:525-533.
5. Flowers HM. Chemistry and biochemistry of D- and L-fucose. Adv Carbohydr Chem Biochem. 1981;39:279-345.
6. Wiese TJ, Dunlap JA, Yorek MA. L-fucose is accumulated via a specific transport system in eukaryotic cells. J Biol Chem. 1994;269:22705-22711.
7. Feizi T. Carbohydrate differentiation antigens: probable ligands for cell adhesion molecules. Trends Biochem Sci. 1991;16:84-86.
8. Lowe JB. Specificity and expression of carbohydrate ligands. In: Wegner CD, ed. Adhesion Molecules. London, England: Academic Press; 1994:111-140. Page C, series ed. The Handbook of Immunopharmacology.
9. Lowe JB. Specificity and expression of carbohydrate ligands. In: Wegner CD, ed. Adhesion Molecules. London, England: Academic Press; 1994:111-140. Page C, series ed. The Handbook of Immunopharmacology.
10. Fenderson BA, Eddy EM, Hakomori S. Glycoconjugate expression during embryogenesis and its biological significance. Bioessays. 1990;12:173-179.
11. Hakomori S. Possible functions of tumor-associated carbohydrate antigens. Curr Opin Immunol. 1991;3:646-653.
12. Sharon N, Lis H. Carbohydrates in cell recognition. Sci Am. 1993;268:82-89.
13. Chammas R, Veiga SS, Travassos LR, et al. Functionally distinct roles for glycosylation of alpha and beta integrin chains in cell-matrix interactions. Proc Natl Acad Sci U S A. 1993;90:1795-1799.
14. Iglesias M, Soler RM, Ribera J, et al. The carbohydrate N-acetylglucosamine is involved in the guidance of neurites from chick ciliary ganglion neurons through the extracellular matrix of rat skeletal muscle fiber. Neurosci Lett. 1996;207:81-84.
15. Ruoslahti E. Brain extracellular matrix. Glycobiology. 1996;6:489-492.
16. Solter D, Knowles BB. Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1). Proc Natl Acad Sci U S A. 1978;75:5565-5569.
17. Fenderson BA, Zehavi U, Hakomori S. A multivalent lacto-N-fucopenatose III-lysyllysine conjugate decompacts preimplantation mouse embryos, while the free oligosaccharide is ineffective. J Exp Med. 1984;160:1591-1596.
18. y oligosaccharide inhibits implantation in the mouse. Biol Reprod. 1995;52:903-912.
19. x and related structures as adhesion molecules. Histochem J. 1992;24:771-776.
20. Kabat EA. Blood Group Substances. Their Chemistry and Immunochemistry. New York, NY: Academic Press; 1956.
21. Chester MA, Watkins WM. Alpha-L-fucosyltransferases in human submaxillary gland and stomach tissues associated with the H, Lea and Leb blood-group characters and ABH secretor status. Biochem Biophys Res Commun. 1969;34: 835-842.
22. Ginsburg V. Enzymatic basis for blood groups in man. Adv Enzymol Relat Areas Mol Biol. 1972;36:131-149.
23. Hindsgaul O, Norberg T, LePendu J, et al. Synthesis of type 2 human blood-group antigenic determinants: the H, X, and Y haptens and variations of the H type 2 determinant as probes for the combining site of the lectin I of Ulex europaeus. Carbohydr Res. 1982;109:109-142.
24. Macher BA, Holmes EH, Swiedler SJ, et al. Human alpha 1-3 fucosyltransferases. Glycobiology. 1991;1:577-584.
25. Butcher EC. Cellular and molecular mechanisms that direct leukocyte traffic. Am J Pathol. 1990;136:3-12.
26. Butcher EC. Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell. 1991;67:1033-1036.
27. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell. 1994;76: 301-314.
28. Sharon N, Lis H. Lectins: proteins with a sweet tooth: functions in cell recognition. Essays Biochem. 1995;30:59-75.
29. Bevilacqua M, Butcher E, Furie B, et al. Selectins: a family of adhesion receptors [letter]. Cell. 1991;67:233.
30. Forrest M, Paulson JC. Selectin family of adhesion molecules. In: Granger DN, Schmid-Schönbein GW, eds. Physiology and Pathophysiobgy of Leukocyte Adhesion. New York, NY: Oxford University Press; 1995:43-50.
31. Mayadas TN. Selectins. In: Brodt P, ed. Cell Adhesion and Invasion in Cancer Metastasis. New York, NY: Chapman and Hall (R. G. Landes); 1996:77-92.
32. Erbe DV, Wolitzky BA, Presta LG, et al. Identification of an E-selectin region critical for carbohydrate recognition and cell adhesion. J Cell Biol. 1992;119:215-227.
33. Erbe DV, Watson SR, Presta LG, et al. P- and E-selectin use common sites for carbohydrate ligand recognition and cell adhesion. J Cell Biol. 1993;120:1227-1235.
34. Winn RK, Sharar SR, Vedder NB, et al. Leukocyte and endothelial adhesion molecules in ischaemia/reperfusion injuries. In: Marsh J, ed. Cell Adhesion and Human Disease. Ciba Foundation Symposium 189. Chichester, United Kingdom: Wiley; 1995:63-76.
35. Tyrrell D, James P, Rao N, et al. Structural requirements for the carbohydrate ligand of E-selectin. Proc Natl Acad Sci U S A. 1991;88:10372-10376.
36. Polley MJ, Phillips ML, Wayner E, et al. CD62 and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1) recognize the same carbohydrate ligand, sialyl-Lewis x. Proc Natl Acad Sci U S A. 1991;88:6224-6228.
37. Rosen SD, Bertozzi CR. The selectins and their ligands. Curr Opin Cell Biol. 1994;6:663-673.
38. Varki A. Selectin ligands. Proc Natl Acad Sci U S A. 1994; 91:7390-7397.
39. Feizi T. Oligosaccharides that mediate mammalian cell-cell adhesion. Curr Opin Struct Biol. 1993;3:701-710.
40. Sherburne R, Taylor DE. Helicobacter pylori expresses a complex surface carbohydrate, Lewis X. Infect Immun. 1995;63:4564-4568.
41. Garratty G. Blood group antigens as tumor markers, parasitic/bacterial/viral receptors, and their association with immunologically important proteins. Immunol Invest. 1995;24:213-232.
42. Khoo KH, Sarda S, Xu X, et al. A unique multifucosylated - 3GalNAc β 1→4GlcNAc β 1→3Gal α 1-motif O-glycans derived from the cercarial glycocalyx of Schistosoma mansoni. J Biol Chem. 1995;270:17114-17123.
43. Cummings RD, Nyame AK. Glycobiology of schistosomiasis. FASEB J. 1996;10:838-848.
44. + symport protein, FucP, from Escherichia coli. Mol Microbiol. 1995;15:771-783.
45. Bernard A, Boumsell L. The clusters of differentiation (CD) defined by the First International Workshop on Human Leucocyte Differentiation Antigens. Hum Immunol. 1984;11:1-10.
46. Kishimoto T, Goyert S, Kikutani H, et al. Update of CD antigens, 1996. J Immunol. 1997;158:3035-3036.
47. Hanjan SNS, Kearney JF, Cooper MD. A monoclonal antibody (MMA) that identifies a differentiation antigen on human myelomonocytic cells. Clin Immunol Immunopathol. 1982;23:172-188.
48. Sheibani K, Battifora H, Burke JS. Antigenic phenotype of malignant mesotheliomas and pulmonary adenocarcinomas: an immunohistologic analysis demonstrating the value of Leu M1 antigen. Am J Pathol. 1986;123:212-219.
49. Ordonez NG. The immunohistochemical diagnosis of mesothelioma: differentiation of mesothelioma and lung adenocarcinoma. Am J Surg Pathol. 1989;13:276-291.
50. Gooi HC, Feizi T, Kapadia A, et al. Stage-specific embryonic antigen involves alpha 1 goes to 3 fucosylated type 2 blood group chains. Nature. 1981;292:156-158.
51. Huang LC, Civin CI, Magnani JL, et al. My-1, the human myeloid-specific antigen detected by mouse monoclonal antibodies, is a sugar sequence found in lacto-N-fucopentaose III. Blood. 1983; 61:1020-1023.
52. Gooi HC, Thorpe SJ, Hounsell EF, et al. Marker of peripheral blood granulocytes and monocytes of man recognized by two monoclonal antibodies VEP8 and VEP9 involves the trisaccharide 3-fucosyl-N-acetyllactosamine. Eur J Immunol. 1983;13:306-312.
53. Pinkus GS, Thomas P, Said JW. Leu-M1: a marker for Reed-Sternberg cells in Hodgkin's disease: An immunoperoxidase study of paraffin-embedded tissues. Am J Pathol. 1985;119:244-252.
54. Hakomori S. Glycolipids: their chemical pattern, synthesis and degradation in normal and tumor cells. In: Wood R, ed.Tumor Lipids: Biochemistry and Metabolism. Champaign, Ill: American Oil Chemists' Society Press; 1973:269-284.
55. Smets LA, van Beek WP. Carbohydrates of the tumor cell surface. Biochim Biophys Acta. 1984;738:237-249.
56. Lloyd KO. Philip Levine Award Lecture. Blood group antigens as markers for normal differentiation and malignant change in human tissues. Am J Clin Pathol. 1987;87:129-139.
57. Muramatsu T. Mini review: carbohydrate signals in metastasis and prognosis of human carcinomas. Glycobiology. 1993;3:291-296.
58. Fukuda M. Possible roles of tumor-associated carbohydrate antigens. Cancer Res. 1996;56:2237-2244.
59. Greenwell P. Blood group antigens: molecules seeking a function? Glycoconj J. 1997;14:159-173.
60. x antigen correlates with poor survival in patients with colorectal carcinoma: clinicopathological and immunohistochemical study. Cancer Res. 1993;53:3632-3637.
61. Narita T, Funahashi H, Satoh Y, et al. Association of expression of blood group-related carbohydrate antigens with prognosis in breast cancer. Cancer. 1993;71:3044-3053.
62. Myers RB, Grizzle WE. Biomarker expression in prostatic intraepithelial neoplasia. Eur Urol. 1996;30:153-166.
63. Grizzle WE, Myers RB, Manne U. The use of biomarker expression to characterize neoplastic processes. Biotech Histochem. 1997;72:96-104.
64. x synthesis and patient survival from lung carcinoma. Cancer. 1997;79:1678-1685.
65. Trail PA, Willner D, Lasch SJ, et al. Cure of xenografted human carcinomas by BR96-doxorubicin immunoconjugates. Science. 1993;261:212-215.
66. Siegall CB. Targeted therapy of carcinomas using BR96 sFv-PE40, a single-chain immunotoxin that binds to the Le(y) antigen. Semin Cancer Biol. 1995;6:289-295.
67. Okada Y, Sotozono M, Sakai N, et al. Fucosylated Thomsen-Friedenreich antigen in alpha-anomeric configuration in human gastric surface epithelia: an allogeneic carbohydrate antigen possibly controlled by the Se gene. J Histochem Cytochem. 1994;42:371-376.
68. Graves BJ, Crowther RL, Chandran C, et al. Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains. Nature. 1994;367:532-538.
69. Weis WL, Drickamer K, Hendrickson WA. Structure of a c-type mannose-binding protein complexed with an oligosaccharide. Nature. 1992;360:127-134.
70. Ng KK, Weis WI. Structure of a selectin-like mutant of mannose-binding protein complexed with sialylated and sulfated Lewis(x) oligosaccharides. Biochemistry. 1997;36:979-988.
71. Cook WJ, Bugg CE. Calcium-carbohydrate bridges composed of uncharged sugars: structure of a hydrated calcium bromide complex of α-fucose. Biochim Biophys Acta. 1975;389:428-435.
72. Wright LC, May GL, Gregory P, et al. Inhibition of metastatic potential by fucosidase: an NMR study identifies a cell surface metastasis marker. J Cell Biochem. 1988;37:49-59.
73. Listinsky JJ, Listinsky CM, Myers RB, et al. Alpha-fucosidase reduces the invasiveness of DU-145 prostate carcinoma cells in vitro. Mod Pathol. 1996;9:147A. Abstract.
74. x determinants. J Biol Chem. 1989;264:9476-9484.
75. x expression. Glycoconj J. 1994;11:238-248.
76. Larsen E, Palabrica T, Sajer S, et al. PADGEM-dependent adhesion of platelets to monocytes and neutrophils is mediated by a lineage-specific carbohydrate, LNF III (CD15). Cell. 1990;63:467-474.
77. Larkin M, Ahern TJ, Stoll MS, et al. Spectrum of sialylated and nonsialylated fuco-oligosaccharides bound by the endothelial-leukocyte adhesion molecule E-selectin. J Biol Chem. 1992;267:13661-13668.
78. Kojima N, Handa K, Newman W, et al. Multi-recognition capability of E-selectin in a dynamic flow system, as evidenced by differential effects of sialidases and anti-carbohydrate antibodies on selectin-mediated cell adhesion at low is high wall shear stress: a preliminary note. Biochem Biophys Res Commun. 1992;189:1686-1694.
79. Dejana E, Martin-Padura I, Lauri D, et al. Endothelial leukocyte adhesion molecule-1-dependent adhesion of colon carcinoma cells to vascular endothelium is inhibited by an antibody to Lewis fucosylated type I carbohydrate chain. Lab Invest. 1992;66:324-330.
80. Norgard K, Moore K, Diaz S, et al. Characterization of a specific ligand for P-selectin on myeloid cells. J Biol Chem. 1993;268:12764-12774.
81. Brandley BK, Kiso M, Abbas S, et al. Structure-function studies on selectin carbohydrate ligands: modifications to fucose, sialic acid and sulphate as a sialic acid replacement. Glycobiology.. 1993;3:633-639.
82. Cappi MW, Moree WJ, Qiao L, et al. Synthesis of novel 6-amido-6-deoxy-L-galactose derivatives as sialyl Lewis X mimetics. BioorgMed Chem. 1997;5:283-296.
83. Rao B, Anderson M, Musser J, et al. Sialyl Lewis X mimics derived from a pharmacophore search are selectin inhibitors with anti-inflammatory activity. J Biol Chem. 1994;269: 19663-19666.
84. y) defined by monoclonal antibody AH6 in different locations of colonic epithelia, various histological types of colonic polyps, and adenocarcinomas. Cancer Res. 1986;46:2639-2644.
85. x carbohydrate antigen in benign and malignant gastrointestinal mucosa. Cancer. 1994;73:1552-1561.
86. Hakomori S, Nudelman E, Levery SB, et al. Novel fucolipids accumulating in human adenocarcinoma, I: glycolipids with di- or trifucosylated type 2 chain. J Biol Chem. 1984;259: 4672-4680.
87. Fukushi Y, Hakomori S, Nudelman E, et al. Novel fucolipids accumulating in human adenocarcinoma, II: selective isolation of hybridoma antibodies that differentially recognize mono-, di-, and trifucosylated type 2 chain. J Biol Chem. 1984;259:4681-4685.
88. 6). J Biol Chem. 1984;259:10511-10517.
89. 6). J Biol Chem. 1986;261:11247-11253.
90. Ishihara H, Hattori H. Establishment and characterization of a mouse monoclonal anti-fucosylceramide antibody, PC47H. Cancer Res. 1991;51:4182-4186.
91. 6) as human tumor-associated antigen. J Biol Chem. 1991;266: 8439-8446.
92. Vangsted AJ, Zeuthen J. Monoclonal antibodies for diagnosis and potential therapy of small cell lung cancer: the ganglioside antigen fucosyl-GM1. Acta Oncol. 1993;32:845-851.
93. Foltz CM, Russo RG, Siegal GP, et al. Interactions of tumor cells with whole basement membrane in the presence or absence of endothelium. Prog Clin Biol Res. 1982;89:353-371.
94. Weiss L, Ward PM. Cell detachment and metastasis. Cancer Metastasis Rev. 1983;2:111-127.
95. Kohn EC, Liotta LA. Invasion and metastasis: new approaches to an old problem. Oncology. 1993;7:47-52.
96. Albelda SM. Role of cell adhesion molecules in tumor progression and metastasis. In: Wegner CD, ed. Adhesion Molecules. London, England: Academic Press; 1994:71-58. Page C, series ed. The Handbook of Immunopharmacology.
97. Albelda SM. Role of cell adhesion molecules in tumor progression and metastasis. In: Wegner CD, ed. Adhesion Molecules. London, England: Academic Press; 1994:71-58. Page C, series ed. The Handbook of Immunopharmacology.
98. Levine MD, Liotta LA, Stracke ML. Stimulation and regulation of tumor cell motility in invasion and metastasis. EXS. 1995;74:157-179.
99. McCormick BA, Zetter BR. Adhesive interactions in angiogenesis and metastasis. Pharmacol Ther. 1992;53: 239-260.
100. Effert PJ, Strohmeyer TG. Theories on the metastatic process and possible therapeutic options. Urol Res. 1995;23:11-19.
101. Zetter BR. Adhesion molecules in tumor metastasis. Semin Cancer Biol. 1993;4:219-229.
102. Brodt P. Adhesion receptors and proteolytic mechanisms in cancer invasion and metastasis. In: Brodt P, ed. Cell Adhesion and Invasion in Cancer Metastasis. New York, NY: Chapman and Hall (R. G. Landes); 1996:167-242.
103. Vaz WLC, Almeida PFF. Phase topology and percolation in multi-phase lipid bilayers: is the biological membrane a domain mosaic? Curr Opin Struct Biol. 1993;3:482-488.
104. Lauri D, Needham L, Martin-Padura I, et al. Tumor cell adhesion to endothelial cells: endothelial leukocyte adhesion molecule-1 as an inducible adhesive receptor specific for colon carcinoma cells. J Natl Cancer Inst. 1991;83:1321-1324.
105. Walker RA, Day SJ. The expression of fucosylated type 2 blood group chains in human breast and their significance. J Pathol. 1986;149:113-120.
106. Nakagoe T, Fukushima K, Hirota M, et al. Immunohistochemical expression of blood group substances and related carbohydrate antigens in breast carcinoma. Jpn J Cancer Res. 1991;82:559-568.
107. Brooks SA, Leathern AJ. Expression of the CD15 antigen (Lewis x) in breast cancer. Histochem J. 1995;27:689-693.
108. Gardner MJ, Jones LM, Catterall JB, et al. Expression of cell adhesion molecules on ovarian tumour cell lines and mesothelial cells, in relation to ovarian cancer metastasis. Cancer Lett. 1995;91:229-234.
109. y) blood group antigen expression in epithelial ovarian cancer. Int J Cancer. 1996;65:406-412.
110. Lloyd K, Yin BW, Kudryashov V. Isolation and characterization of ovarian cancer antigen CA 125 using a new monoclonal antibody (VK-8): identification as a mucin-type molecule. Int J Cancer. 1997;71:842-850.
111. x and related carbohydrate antigens in the prostate. Hum Pathol. 1995;26:735-739.
112. Myers RB, Srivastava S, Grizzle WE. Lewis Y antigen as detected by the monoclonal antibody BR96 is expressed strongly in prostatic adenocarcinoma. J Urol. 1995;153: 1572-1574.
113. Jorgensen T, Berner A, Kaalhus O, et al. Up-regulation of the oligosaccharide sialyl Lewis X: a new prognostic parameter in metastatic prostate cancer. Cancer Res. 1995;55:1817-1819.
114. a antigens in human lung carcinoma. Tohoku J Exp Med. 1991;163:17-30.
115. Brezicka FT, Oiling S, Bergman B, et al. Coexpression of ganglioside antigen fuc-GM1, neural-cell adhesion molecule, carcinoembryonic antigen, and carbohydrate tumor-associated antigen CA 50 in lung cancer. Tumor Biol. 1992;13:308-315.
116. Kawai T, Suzuki M, Kase K, et al. Expression of carbohydrate antigens in human pulmonary adenocarcinoma. Cancer. 1993;72:1581-1587.
117. Ikeda Y, Mori M, Kamakura T, et al. Immunohistochemical expression of sialyl Tn and sialyl Lewis(a) antigens in stromal tissue correlates with peritoneal dissemination in stage IV human gastric cancer. Eur J Surg Oncol. 1995; 21:168-175.
118. Umeda T, Sakamoto J, Watanabe T, et al. Immunohistochemical analysis of the poorly differentiated stomach adenocarcinoma with medullary growth pattern. J Surg Oncol. 1996;62:34-39.
119. Nakashio T, Narita T, Sato M, et al. The association of metastasis with the expression of adhesion molecules in cell lines derived from human gastric cancer. Anticancer Res. 1997;17:293-299.
120. Kawa S, Tokoo M, Hasebe O, et al. Comparative study of CA242 and CA19-9 for the diagnosis of pancreatic cancer. Br J Cancer. 1994;70:481-486.
121. Ohta H, Sawabu N, Takemori Y, et al. Measurement of sialylated stage-specific embryonic antigen-1 in pure pancreatic juice for the diagnosis of pancreatic cancer. Int J Pancreatol. 1994;15:35-41.
122. Takada M, Yamamoto M, Hasegawa Y, et al. Endothelial leukocyte adhesion molecule-1-mediated vasoinvasion of human pancreatic adenocarcinoma. J Surg Res. 1995;59:653-657.
123. Kishimoto T, Ishikura H, Kimura C, et al. Phenotypes correlating to metastatic properties of pancreas adenocarcinoma in vivo: the importance of surface sialyl Lewis(a) antigen. Int J Cancer. 1996;69:290-294.
124. Podczaski E, Kaminski PF, Zaino R. CA 125 and CA 19-9 immunolocalization in normal, hyperplastic, and carcinomatous endometrium. Cancer. 1993;71:2551-2556.
125. Kubushiro K, Tsukazaki K, Sakuma Y, et al. Enzymatic basis for the accumulation of Lewis(b) antigen in uterine endometrial cancer. Jpn J Cancer Res. 1995;86:361-367.
126. Wang JW, Ambros RA, Weber PB, et al. Fucosyltransferase and alpha-L-fucosidase activities and fucose levels in normal and malignant endometrial tissue. Cancer Res. 1995;55: 3654-3658.
127. Martensson S, Brunmark C, Ohlsson L, et al. Heterogeneity of renal carcinoma. Nephrol Dial Transplant. 1995;10:1637-1643.
128. Steinbach F, Tanabe K, Alexander J, et al. The influence of cytokines on the adhesion of renal cancer cells to endothelium. J Urol. 1996;155:743-748.
129. Koga H, Naito S, Nakashima M, et al. A flow cytometric analysis of the expression of adhesion molecules on human renal cell carcinoma cells with different metastatic potentials. Eur Urol. 1997;31:86-91.
130. Shirahama T, Ikoma M, Muramatsu H, et al. Reactivity to fucose-binding proteins of Lotus tetragonolobus correlates with metastatic phenotype of transitional cell carcinoma of the bladder. J Urol 1992;147:1659-1664.
131. Sagerman PM, Saigo PE, Sheinfeld J, et al. Enhanced detection of bladder cancer in urine cytology with Lewis X, M344and 19A211 antigens. Acta Cytol. 1994;38:517-523.
132. Konety BR, Ballou B, Jaffe R, et al. Expression of SSEA-1 (Lewis(x)) on transitional cell carcinoma of the bladder. Urol Int. 1997;58:69-74.
133. Schroder S, Dralle H. Prognostic factors in medullary thyroid carcinomas. Horm Metab Res Suppl. 1989;21:26-28.
134. Vierbuchen M, Larena A, Schroder S, et al. Blood group antigen expression in medullary carcinoma of the thyroid: an immunohistochemical study on the occurrence of type 1 chain-derived antigens. Virchows Arch B Cell Pathol Incl Mol Pathol. 1992;62:79-88.
135. Miettinen M, Karkkainen P. Differential reactivity of HBME-1 and CD15 antibodies in benign and malignant thyroid tumours: preferential reactivity with malignant tumours. Virchows Arch. 1996;429:213-219.
136. Hsu SM, Jaffe ES. Leu M1 and peanut agglutinin stain the neoplastic cells of Hodgkin's disease. Am J Clin Pathol. 1984;82:29-32.
137. Davey FR, Elghetany MT, Kurec AS. Immunophenotyping of hematologic neoplasms in paraffin-embedded tissue sections. Am J Clin Pathol. 1990;93(4 suppl1):S17-S26.
138. Kageshita T, Hirai S, Kimura T, et al. Association between sialyl Lewis(a) expression and tumor progression in melanoma. Cancer Res. 1995;55:1748-1751.
139. Miller N, Vile RG, Hart IR. Selectin ligands on human melanoma cells. Glycoconj J. 1996;13:33-43.
140. a are differentiation antigens immunogenic in human melanoma. Cancer. 1997;79:1686-1697.
141. Santer UV, Glick MC. Presence of fucosyl residues on the oligosaccharide antennae of membrane glycopeptides of human neuroblastoma cells. Cancer Res. 1983;43:4159-4166.
142. Woodbury RA, Santer UV, Elkins WL, et al. Similarities in glycosylation of human neuroblastoma tumors and cell lines. Cancer Res. 1986;46:3692-3697.
143. Stone JP, Wagner DD. P-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancer. J Clin Invest. 1993;92:804-813.
144. Okada Y, Arima T, Togawa K, et al. Neoexpression of ABH and Lewis blood group antigens in human hepatocellular carcinomas. J Natl Cancer Inst. 1987;78:19-28.
145. Jagirdar J, Thung SN, Shah KD, et al. Expression of sialylated Lewis(x) antigen in chronic and neoplastic liver diseases. Arch Pathol Lab Med. 1992;116:643-648.
146. x: a hepatic necroinflammation-associated carbohydrate neoantigen, in human hepatocellular carcinomas. Cancer. 1994;73:1811-1816.
147. Wakabayashi M, Shiro T, Seki TT, et al. Lewis Y antigen expression in hepatocellular carcinoma: an immunohistochemical study. Cancer. 1995;75:2827-2835.
148. Wick MR, Cooper PH, Swanson PE, et al. Microcystic adnexal carcinoma: an immunohistochemical comparison with other cutaneous appendage tumors. Arch Dermatol. 1990;126:189-194.
149. Groves RW, Allen MH, Ross EL, et al. Expression of selectin ligands by cutaneous squamous cell carcinoma. Am J Pathol. 1993;143:1220-1225.
150. Ansai S, Hashimoto H, Aoki T, et al. A histochemical and immunohistochemical study of extra-ocular sebaceous carcinoma. Histopathology. 1993;22:127-133.
151. Takada A, Ohmori K, Yoneda T, et al. Contribution of carbohydrate antigens sialyl Lewis A and sialyl Lewis X to adhesion of human cancer cells to vascular endothelium. Cancer Res. 1993;53:354-361.
152. Furukawa Y, Tara M, Ohmori K, et al. Variant type of sialyl Lewis X antigen expressed on adult T cell leukemia cells is associated with skin involvement. Cancer Res. 1994;54: 6533-6538.
153. Robinson NE, de Vries T, Davis RE, et al. Expression of fucosylated antigens and alpha 1,3 fucosyltransferases in human leukaemia cell lines. Glycobiology. 1994;4:317-326.
154. Uchiyama T, Ishikawa T, Imura A. Adhesion properties of adult T cell leukemia cells. Leuk Lymphoma. 1995;16:407-412.
155. Nakamori S, Kameyama M, Imaoka S, et al. Involvement of carbohydrate antigen sialyl Lewis(x) in colorectal cancer metastasis. Dis Colon Rectum. 1997;40:420-431.
156. Chandrasekaran EV, Jain RK, Matta KL. Ovarian cancer α1,3-L-fucosyltransferase: differentiation of distinct catalytic species with the unique substrate, 3′-sulfo-N-acetyllactosamine in conjunction with other synthetic acceptors. J Biol Chem. 1992;267:23806-23814.
157. Thompson S, Cantwell BMJ, Matta KL, et al. Parallel changes in the blood levels of abnormally-fucosylated haptoglobin and alpha 1,3 fucosyltransferase in relationship to tumour burden: more evidence for a disturbance of fucose metabolism in cancer. Cancer Lett. 1992;65:115-121.
158. Ogawa J, Inoue H, Koide S. Glucose-transporter-type-1-gene amplification correlates with sialyl-Lewis-x synthesis and proliferation in lung cancer. Int J Cancer. 1997;74:189-192.
159. Ono M, Sakamoto M, Ino Y, et al. Cancer cell morphology at the invasive front and expression of cell adhesion-related carbohydrate in the primary lesion of patients with colorectal carcinoma with liver metastasis. Cancer. 1996;78:1179-1186.
160. Garrigues J, Anderson J, Hellstrom KE, et al. Anti-tumor antibody BR96 blocks cell migration and binds to a lysosomal membrane glycoprotein on cell surface microspikes and ruffled membranes. J Cell Biol. 1994;125:129-142.
161. Schwartz R, Schirrmacher V, Muhlradt PF. Glycoconjugates of murine tumor lines with different metastatic capacities, I: differences in fucose utilization and in glycoprotein patterns. Int J Cancer. 1984;33:503-509.
162. Matsusako T, Muramatsu H, Shirahama T, et al. Expression of a carbohydrate signal, sialyl dimeric Le(x) antigen, is associated with metastatic potential of transitional cell carcinoma of the human urinary bladder. Biochem Biophys Res Commun. 1991;181:1218-1222.
163. 1H magnetic resonance spectroscopy. Int J Cancer. 1994;59:248-261.
164. Kojima N, Handa K, Newman W, et al. Inhibition of selectin-dependent tumor cell adhesion to endothelial cells and platelets by blocking O-glycosylation of these cells. Biochem Biophys Res Commun. 1992;182:1288-1295.
165. Dennis JW, Kerbel RS. Characterization of a deficiency in fucose metabolism in lectin-resistant variants of a murine tumor showing altered tumorigenic and metastatic capacities in vivo. Cancer Res. 1981;41:98-104.
166. Maly P, Thall A, Petryniak B, et al. The alpha(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. Cell. 1996;86:643-653.
167. Biancone L, Araki M, Araki K, et al. Redirection of tumor metastasis by expression of E-selectin in vivo. J Exp Med. 1996;183:581-587.
168. Labarriere N, Piau J-P, Zennadi R, et al. Retinoic acid modulation of a(1→2) fucosyltransferase activity and sensitivity of tumor cells to LAK-mediated cytotoxicity. In Vitro Cell Dev Biol Anim. 1993;29A:140-144.
169. Blottiere HM, Burg C, Zennadi R, et al. Involvement of histoblood-group antigens in the susceptibility of colon carcinoma cells to natural killer-mediated cytotoxicity. Int J Cancer. 1992;52:609-618.
170. Amos B, Lotan D, Lotan R. Increased fucosylation of high-molecular-weight glycoproteins accompanies retinoic-acid-induced differentiation of F-9 embryonal carcinoma cells. Int J Cancer. 1990;46:86-94.
171. Amos B, Deutsch V, Lotan R. Modulation by all-trans retinoic acid of glycoprotein glycosylation in murine melanoma cells: enhancement of fucosyl- and galactosyltransferase activities. Cancer Biochem Biophys. 1990;11:31-43.
172. Sacks PG, Amos B, Lotan R. Enhancement of glycosylation of cellular glycoconjugates in the squamous carcinoma cell line MDA886LN by beta-all-trans retinoic acid. Glycoconj J. 1996;13:791-796.
173. Toppila S, Lauronen J, Mattila P, et al. L-selectin ligands in rat high endothelium: multivalent sialyl Lewis x glycans are high-affinity inhibitors of lymphocyte adhesion. Eur J Immunol. 1997;27:1360-1365.
174. Ramphal J, Zheng Z-L, Perez C, et al. Structure-activity relationships of sialyl Lewis x-containing oligosaccharides, I: effect of modifications of the fucose moiety. J Med Chem. 1994;37:3459-3463.
175. Pastan I, Lovelace E, Gallo M, et al. Characterization of monoclonal antibodies B1 and B3 that react with mucinous adenocarcinomas. Cancer Res. 1991;51:3781-3787.
176. Cualing H, Siegel R, Schwarting GA, et al. The expression of H-like blood group glycolipids in small cell carcinoma of the lung. Hybridoma. 1993;12:239-247.
177. Lafrenie RM, Buchanan MR, Orr FW. Adhesion molecules and their role in cancer metastasis. Cell Biochem Biophys. 1993;23:3-89.
178. Tang DG, Honn KV. Adhesion molecules and tumor metastasis: an update. Invasion Metastasis. 1994;14:109-122.
179. Tuszynski GP, Wang TN, D Berger. Adhesive proteins and the hematogenous spread of cancer. Acta Haematol. 1997;97:29-39.
180. Helland IB, Klementsen B, Jorgensen L. Addition of both platelets and thrombin in combination accelerates tumor cells to adhere to endothelial cells in vitro. In Vitro Cell Dev Biol Anim. 1997;33:182-186.
181. Daneker GW, Lund SA, Caughman SW, et al. Anti-metastatic prostacyclins inhibit the adhesion of colon carcinoma to endothelial cells by blocking E-selectin expression. Clin Exp Metastasis. 1996;14:230-238.
182. Narita T, Kawakami-Kimura N, Matsuura N, et al. Corticosteroids and medroxyprogesterone acetate inhibit the induction of E-selectin on the vascular endothelium by MDA-MB-231 breast cancer cells. Anticancer Res. 1995;15:2523-2527.
183. Tozawa K, Sakurada S, Kohri K, et al. Effects of anti-nuclear factor kappa B reagents in blocking adhesion of human cancer cells to vascular endothelial cells. Cancer Res. 1995;55:4162-4167.
184. Chirivi RG, Garofalo A, Padura IM, et al. Interleukin 1 receptor antagonist inhibits the augmentation of metastasis induced by interleukin 1 or lipopolysaccharide in a human melanoma/nude mouse system. Cancer Res. 1993;53: 5051-5054.
185. Pienta KJ, Naik H, Akhtar A, et al. Inhibition of spontaneous metastasis in a rat prostate cancer model by oral administration of modified citrus pectin. J Natl Cancer Inst. 1995;87:348-353.
186. Chandrasekaran EV, Jain RK, Rhodes JM, et al. Expression of blood group Lewis b determinant from Lewis a: association of this novel alpha (1,2)-L-fucosylating activity with the Lewis type alpha (1,3/4)-L-fucosyltransferase. Biochemistry. 1995;34:4748-4756.
187. Murray BW, Wittmann V, Burkart MD, et al. Mechanism of human alpha-1,3-fucosyltransferase V: glycosidic cleavage occurs prior to nucleophilic attack. Biochemistry. 1997;36:823-831.
188. 2+-dependent sugar recognition by animal lectins. Biochem Soc Trans. 1996;24:146-150.
189. Hakomori S, Igarashi Y. Gangliosides and glycosphingolipids as modulators of cell growth, adhesion, and transmembrane signaling. Adv Lipid Res. 1993;25:147-162.
190. Varki A. Biological roles of oligosaccharides: all of the theories are correct. Glycobiology. 1993;3:97-130.
191. Fuhlbrigge RC, Alon R, Puri KD, et al. Sialylated, fucosylated ligands for L-selectin expressed on leukocytes mediate tethering and rolling adhesions in physiologic flow conditions. J Cell Biol. 1996;135:837-848.
192. Chen S, Alon R, Fuhlbrigge RC, et al. Rolling and transient tethering of leukocytes on antibodies reveal specializations of selectins. Proc Natl Acad Sci U S A. 1997;94:3172-3177.