N-Isonicotinoyl-(L)-4-aminophenylalanine derivatives as tight binding VLA-4 antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 11, 2003, Pages 1891-1895

  Doherty, George A ^a   Yang, Ginger X ^a   Borges, Edite ^a   Tong, Sharon ^a   McCauley, Ermengilda D ^a   Treonz, Kelly M ^a   Van Riper, Gail ^a   Pacholok, Stephen ^a   Si, Qian ^a   Koo, Gloria C ^a   Shah, Kashmira ^a   Mumford, Richard A ^a   Hagmann, William K ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; N ISONICOTINOYL 4 AMINOPHENYLALANINE; PHENYLALANINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; DOG; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; DRUG HALF LIFE; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; DRUG SCREENING; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL LINE; MOLECULAR WEIGHT; MONKEY; NONHUMAN; STRUCTURE ACTIVITY RELATION;

EID: 12444302271     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00308-1     Document Type: Article

References (19)

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