Comparison between δ-opioid receptor functional response and autoradiographic labeling in rat brain and spinal cord

Journal of Comparative Neurology

Volumn 481, Issue 4, 2005, Pages 416-426

  Ali Pradhan, Amynah Amir ^a   Clarke, Paul Brian Sydenham ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Analgesia; Opiates; Receptor localization; Reward

Indexed keywords

ARM 100613; DELTA OPIATE RECEPTOR; DELTORPHIN; DELTORPHIN 2; GUANYLYL 5' O(GAMMA THIO)TRIPHOSPHATE; IODINE 125; NALTRINDOLE; RADIOISOTOPE; RECEPTOR BLOCKING AGENT; SULFUR 35; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN CORTEX; BRAIN FUNCTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ISOTOPE LABELING; LIGAND BINDING; MALE; NONHUMAN; NUCLEUS ACCUMBENS; OLFACTORY BULB; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PUTAMEN; RAT; RECEPTOR BINDING; SPINAL CORD FUNCTION;

ANALGESIA; ANIMALS; AUTORADIOGRAPHY; BRAIN; MALE; OLIGOPEPTIDES; PAIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, DELTA; SPINAL CORD; TISSUE DISTRIBUTION;

EID: 12444292138     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/cne.20378     Document Type: Article

References (66)

1. Arvidsson U, Dado RJ, Riedl M, Lee JH, Law PY, Loh HH, Elde R, Wessendorf MW. 1995. Delta-opioid receptor immunoreactivity: distribution in brainstem and spinal cord, and relationship to biogenic amines and enkephalin. J Neurosci 15:1215-1235.
2. Besse D, Lombard MC, Zajac JM, Roques BP, Besson JM. 1990. Pre- and postsynaptic distribution of mu, delta and kappa opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cord. Brain Res 521:15-22.
3. Blackburn TP, Cross AJ, Hille C, Slater P. 1988. Autoradiographic localization of delta opiate receptors in rat and human brain. Neuroscience 27:497-506.
4. Buzas B, Izenwasser S, Portoghese PS, Cox BM. 1994. Evidence for delta opioid receptor subtypes regulating adenylyl cyclase activity in rat brain. Life Sci 54:L101-L106.
5. Cahill CM, McClellan KA, Morinville A, Hoffert C, Hubatsch D, O'Donnell D, Beaudet A. 2001. Immunohistochemical distribution of delta opioid receptors in the rat central nervous system: evidence for somatodendritic labeling and antigen-specific cellular compartmentalization. J Comp Neurol 440:65-84.
6. Clark MJ, Emmerson PJ, Mansour A, Akil H, Woods JH, Portoghese PS, Remmers AE, Medzihradsky F. 1997. Opioid efficacy in a C6 glioma cell line stably expressing the delta opioid receptor. J Pharmacol Exp Ther 283:501-510.
7. Clarke S, Zimmer A, Zimmer AM, Hill RG, Kitchen I. 2003. Region selective up-regulation of micro-, delta- and kappa-opioid receptors but not opioid receptor-like 1 receptors in the brains of enkephalin and dynorphin knockout mice. Neuroscience 122:479-489.
8. Connor M, Christie MD. 1999. Opioid receptor signalling mechanisms. Clin Exp Pharmacol Physiol 26:493-499.
9. Devine DP, Wise RA. 1994. Self-administration of morphine, DAMGO, and DPDPE into the ventral tegmental area of rats. J Neurosci 14:1978-1984.
10. 125I]AR-M100613, a high-affinity radioligand for delta opioid receptors. Peptides 20:1327-1335.
11. Fraser GL, Pradhan AA, Clarke PB, Wahlestedt C. 2000. Supraspinal antinociceptive response to [D-Pen(2,5)]-enkephalin (DPDPE) is pharmacologically distinct from that to other delta-agonists in the rat. J Pharmacol Exp Ther 295:1135-1141.
12. Goodman RR, Snyder SH, Kuhar MJ, Young WS, III. 1980. Differentiation of delta and mu opiate receptor localizations by light microscopic autoradiography. Proc Natl Acad Sci U S A 77:6239-6243.
13. Goody RJ, Oakley SM, Filliol D, Kieffer BL, Kitchen I. 2002. Quantitative autoradiographic mapping of opioid receptors in the brain of delta-opioid receptor gene knockout mice. Brain Res 945:9-19.
14. 125I][D.Ala2]deltorphin-I. Synapse 13:231-240.
15. Happe HK, Murrin LC. 1990. Tritium quench in autoradiography during postnatal development of rat forebrain. Brain Res 525:28-35.
16. Hille CJ, Fox SH, Maneuf YP, Crossman AR, Brotchie JM. 2001. Antiparkinsonian action of a delta opioid agonist in rodent and primate models of Parkinson's disease. Exp Neurol 172:189-198.
17. 3H]DSLET binding: evidence for distinct delta 1 and delta 2 opioid receptor populations in rat brain. Brain Res 719:85-95.
18. Hosohata Y, Vanderah TW, Burkey TH, Ossipov MH, Kovelowski CJ, Sora I, Uhl GR, Zhang X, Rice KC, Roeske WR, Hruby VJ, Yamamura HI, Lai J, Porreca F. 2000. delta-Opioid receptor agonists produce antinociception and [35S] GTPgammaS binding in mu receptor knockout mice. Eur J Pharmacol 388:241-248.
19. Hudzik TJ, Howell A, Payza K, Cross AJ. 2000. Antiparkinson potential of delta-opioid receptor agonists. Eur J Pharmacol 396:101-107.
20. Hurley RW, Hammond DL. 2000. The analgesic effects of supraspinal mu and delta opioid receptor agonists are potentiated during persistent inflammation. J Neurosci 20:1249-1259.
21. Hyytia P, Ingman K, Soini SL, Laitinen JT, Korpi ER. 1999. Effects of continuous opioid receptor blockade on alcohol intake and up-regulation of opioid receptor subtype signalling in a genetic model of high alcohol drinking. Naunyn Schmiedebergs Arch Pharmacol 360:391-401.
22. Improta G, Broccardo M. 1992. Spinal antinociceptive effects of [D-Ala2]deltorphin II, a novel and highly selective delta-opioid receptor agonist. Peptides 13:1123-1126.
23. Kim KW, Kim SJ, Shin BS, Choi HY. 2001. Ligand binding profiles of delta-opioid receptor in human cerebral cortex membranes: evidence of delta-opioid receptor heterogeneity. Life Sci 68:1649-1656.
24. Kovelowski CJ, Bian D, Hruby VJ, Lai J, Ossipov MH, Porreca F. 1999a. Selective opioid delta agonists elicit antinociceptive supraspinal/spinal synergy in the rat. Brain Res 843:12-17.
25. Kovelowski CJ, Ossipov MH, Hruby VJ, Porreca F. 1999b. Lesions of the dorsolateral funiculus block supraspinal opioid delta receptor mediated antinociception in the rat. Pain 83:115-122.
26. Longoni R, Spina L, Mulas A, Carboni E, Garau L, Melchiorri P, Di Chiara G. 1991. (D-Ala2)deltorphin II: D1-dependent stereotypies and stimulation of dopamine release in the nucleus accumbens. J Neurosci 11:1565-1576.
27. Longoni R, Cadoni C, Mulas A, Di Chiara G, Spina L. 1998. Dopamine-dependent behavioural stimulation by non-peptide delta opioids BW373U86 and SNC 80: 2. Place-preference and brain microdialysis studies in rats. Behav Pharmacol 9:9-14.
28. Mansour A, Khachaturian H, Lewis ME, Akil H, Watson SJ. 1987. Autoradiographic differentiation of mu, delta, and kappa opioid receptors in the rat forebrain and midbrain. J Neurosci 7:2445-2464.
29. Mansour A, Khachaturian H, Lewis ME, Akil H, Watson SJ. 1988. Anatomy of CNS opioid receptors. Trends Neurosci 11:308-314.
30. Mansour A, Fox CA, Burke S, Meng F, Thompson RC, Akil H, Watson SJ. 1994. Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: an in situ hybridization study. J Comp Neurol 350:412-438.
31. Mansour A, Fox CA, Akil H, Watson SJ. 1995. Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications. Trends Neurosci 18:22-29.
32. Mennicken F, Zhang J, Hoffert C, Ahmad S, Beaudet A, O'Donnell D. 2003. Phylogenetic changes in the expression of delta opioid receptors in spinal cord and dorsal root ganglia. J Comp Neurol 465:349-360.
33. 14C-plastic standards for quantitative autoradiography using LKB Ultrofilm or Amersham Hyperfilm. Neurosci Lett 121:211-214.
34. 35S]GTP gamma S binding assays. Trends Pharmacol Sci 24:87-90.
35. Morinville A, Cahill CM, Aibak H, Rymar VV, Pradhan A, Hoffert C, Mennicken F, Stroh T, Sadikot AF, O'Donnell D, Clarke PB, Collier B, Henry JL, Vincent JP, Beaudet A. 2004. Morphine-induced changes in delta opioid receptor trafficking are linked to somatosensory processing in the rat spinal cord. J Neurosci 24:5549-5559.
36. Motulsky HJ, Christopoulos A. 2003. Fitting models to biological data using linear and nonlinear regression. A practical guide to curve fitting. San Diego, CA: GraphPad Software Inc.
37. Narita M, Ohsawa M, Mizoguchi H, Aoki T, Suzuki T, Tseng LF. 2000. Role of the phosphatidylinositol-specific phospholipase C pathway in delta-opioid receptor-mediated antinociception in the mouse spinal cord. Neuroscience 99:327-331.
38. Negri L, Noviello V, Angelucci F. 1991. Behavioural effects of deltorphins in rats. Eur J Pharmacol 209:163-168.
39. Noble F, Cox BM. 1995. Differential regulation of D1 dopamine receptor-and of A2a adenosine receptor-stimulated adenylyl cyclase by mu-, delta 1-, and delta 2-opioid agonists in rat caudate putamen. J Neurochem 65:125-133.
40. Oakley SM, Toth G, Borsodi A, Kieffer BL, Kitchen I. 2003. G-protein coupling of delta-opioid receptors in brains of mu-opioid receptor knockout mice. Eur J Pharmacol 466:91-98.
41. Ossipov MH, Kovelowski CJ, Nichols ML, Hruby VJ, Porreca F. 1995. Characterization of supraspinal antinociceptive actions of opioid delta agonists in the rat. Pain 62:287-293.
42. Park Y, Ma T, Tanaka S, Jang C, Loh HH, Ko KH, Ho IK. 2000. Comparison of G-protein activation in the brain by mu-, delta-, and kappa-opioid receptor agonists in mu-opioid receptor knockout mice. Brain Res Bull 52:297-302.
43. Parkhill AL, Bidlack JM. 2002. Several delta-opioid receptor ligands display no subtype selectivity to the human delta-opioid receptor. Eur J Pharmacol 451:257-264.
44. Paxinos G, Watson C. 1997. The rat brain in stereotaxic coordinates. San Diego, CA: Academic Press.
45. Pinna A, Di Chiara G. 1998. Dopamine-dependent behavioural stimulation by non-peptide delta opioids BW 373U86 and SNC 80: 3. Facilitation of D1 and D2 responses in unilaterally 6-hydroxydopamine-lesioned rats. Behav Pharmacol 9:15-21.
46. Ploj K, Nylander I. 2003. Long-term effects on brain opioid and opioid receptor like-1 receptors after short periods of maternal separation in rats. Neurosci Lett 345:195-197.
47. Reisine T, Law SF, Blake A, Tallent M. 1996. Molecular mechanisms of opiate receptor coupling to G proteins and effector systems. Ann N Y Acad Sci 780:168-175.
48. 3H]-[D-Ala2]-deltorphin-I binding sites in the rat brain. Neuroreport 4:1143-1146.
49. Sanchez-Blazquez P, Garzon J. 1998. delta Opioid receptor subtypes activate inositol-signaling pathways in the production of antinociception. J Pharmacol Exp Ther 285:820-827.
50. Schmidt BL, Tambeli CH, Levine JD, Gear RW. 2002. mu/delta Cooperativity and opposing kappa-opioid effects in nucleus accumbens-mediated antinociception in the rat. Eur J Neurosci 15:861-868.
51. Sharif NA, Hughes J. 1989. Discrete mapping of brain Mu and delta opioid receptors using selective peptides: quantitative autoradiography, species differences and comparison with kappa receptors. Peptides 10:499-522.
52. 35S]guanylyl- 5′-O-(gamma-thio)-triphosphate binding in guinea pig brain. J Comp Neurol 386:562-572.
53. 35S]thio]-triphosphate binding. Proc Natl Acad Sci U S A 92:7242-7246.
54. Sim-Selley LJ, Selley DE, Vogt LJ, Childers SR, Martin TJ. 2000. Chronic heroin self-administration desensitizes mu opioid receptor-activated G-proteins in specific regions of rat brain. J Neurosci 20:4555-4562.
55. Sim-Selley LJ, Sharpe AL, Vogt LJ, Brunk LK, Selley DE, Samson HH. 2002. Effect of ethanol self-administration on mu- and delta-opioid receptor-mediated G-protein activity. Alcohol Clin Exp Res 26:688-694.
56. Sofuoglu M, Portoghese PS, Takemori AE. 1992. delta-Opioid receptor binding in mouse brain: evidence for heterogeneous binding sites. Eur J Pharmacol 216:273-277.
57. Sora I, Funada M, Uhl GR. 1997. The mu-opioid receptor is necessary for [D-Pen2,D-Pen5]enkephalin-induced analgesia. Eur J Pharmacol 324:R1-R2.
58. Spina L, Longoni R, Mulas A, Chang KJ, Di Chiara G. 1998. Dopamine-dependent behavioural stimulation by non-peptide delta opioids BW373U86 and SNC 80: 1. Locomotion, rearing and stereotypies in intact rats. Behav Pharmacol 9:1-8.
59. Svingos AL, Clarke CL, Pickel VM. 1999. Localization of the delta-opioid receptor and dopamine transporter in the nucleus accumbens shell: implications for opiate and psychostimulant cross-sensitization. Synapse 34:1-10.
60. 35S]thio)triphosphate to NG108-15 cell membranes: characterization of agonist and inverse agonist effects. J Pharmacol Exp Ther 283:1276-1284.
61. Takita K, Herlenius EA, Lindahl SG, Yamamoto Y. 1997. Actions of opioids on respiratory activity via activation of brainstem mu-, delta- and kappa-receptors; an in vitro study. Brain Res 778:233-241.
62. Tempel A, Zukin RS. 1987. Neuroanatomical patterns of the mu, delta, and kappa opioid receptors of rat brain as determined by quantitative in vitro autoradiography. Proc Natl Acad Sci U S A 84:4308-4312.
63. Thorat SN, Hammond DL. 1997. Modulation of nociception by microinjection of delta-1 and delta-2 opioid receptor ligands in the ventromedial medulla of the rat. J Pharmacol Exp Ther 283:1185-1192.
64. Wang H, Pickel VM. 2001. Preferential cytoplasmic localization of delta-opioid receptors in rat striatal patches: comparison with plasmalemmal mu-opioid receptors. J Neurosci 21:3242-3250.
65. Zaki PA, Bilsky EJ, Vanderah TW, Lai J, Evans CJ, Porreca F. 1996. Opioid receptor types and subtypes: the delta receptor as a model. Annu Rev Pharmacol Toxicol 36:379-401.
66. Zar JH. 1984. Biostatistical analysis. New York: Prentice-Hall.