Activation of the p38 mitogen-activated protein kinase pathway arrests cell cycle progression and differentiation of immature thymocytes in vivo

Journal of Experimental Medicine

Volumn 191, Issue 2, 2000, Pages 321-334

  Diehl, Nicole L ^a   Enslen, Hervé ^b,c   Fortner, Karen A ^a   Merritt, Chris ^a   Stetson, Nate ^a   Charland, Colette ^a   Flavell, Richard A ^c,d   Davis, Roger J ^b,c   Rincón, Mercedes ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Mitosis; T cells; Thymocyte development; Transgenic mice

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CELL PROLIFERATION; GENE EXPRESSION; IMMUNE SYSTEM; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMOCYTE;

ANIMALS; ANTIGENS, CD44; B-LYMPHOCYTES; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL CYCLE; CELL DIFFERENTIATION; ENZYME ACTIVATION; ENZYME INHIBITORS; IMIDAZOLES; LYMPHOID TISSUE; MAP KINASE KINASE 6; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MITOSIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; RECEPTORS, INTERLEUKIN-2; THYMUS GLAND;

EID: 0034677067     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.2.321     Document Type: Article

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