-
1
-
-
0015231127
-
Structure of the porcine LH- and FSH-releasing hormone I. The proposed amino acid sequence
-
MATSUO H, BABA Y, NAIR RMG, ARIMURA A, SCHALLY AV: Structure of the porcine LH- and FSH-releasing hormone I. The proposed amino acid sequence. Biochem. Biophys. Res. Commun. (1971) 43:1334-1339.
-
(1971)
Biochem. Biophys. Res. Commun.
, vol.43
, pp. 1334-1339
-
-
Matsuo, H.1
Baba, Y.2
Nair, R.M.G.3
Arimura, A.4
Schally, A.V.5
-
2
-
-
0028285865
-
Gonadotrophin-releasing hormone agonists. A guide to use and selection
-
[Erratum in Drugs (1994) 48:326]
-
FILICORI M: Gonadotrophin-releasing hormone agonists. A guide to use and selection. Drugs (1994) 48:41-58 [Erratum in Drugs (1994) 48:326].
-
(1994)
Drugs
, vol.48
, pp. 41-58
-
-
Filicori, M.1
-
3
-
-
0028235123
-
The use of luteinising hormone releasing hormone agonist and antagonists in gynaecological cancers
-
EMONS G, SCHALLY AV: The use of luteinising hormone releasing hormone agonist and antagonists in gynaecological cancers. Hum. Reprod. (1994) 9:1364-1379.
-
(1994)
Hum. Reprod.
, vol.9
, pp. 1364-1379
-
-
Emons, G.1
Schally, A.V.2
-
4
-
-
0026098581
-
Gonadotrophin-releasing hormone and its analogues
-
CONN PM, CROWLEY WF: Gonadotrophin-releasing hormone and its analogues. N. Engl. J. Med. (1991) 324:93-103.
-
(1991)
N. Engl. J. Med.
, vol.324
, pp. 93-103
-
-
Conn, P.M.1
Crowley, W.F.2
-
5
-
-
0344444706
-
Gonadotrophin-releasing hormone antagonists
-
HERBST KL: Gonadotrophin-releasing hormone antagonists. Curr. Opin. Pharmacol. (2003) 3:660-666.
-
(2003)
Curr. Opin. Pharmacol.
, vol.3
, pp. 660-666
-
-
Herbst, K.L.1
-
7
-
-
0037413559
-
Discovery of a thieno [2,3-d] pyrimidine-2.4-dione bearing a p-methoxyureidophenyl moiety at the position 6: A highly potent and orally bioavailable non-peptide antagonist for human luteinising hormone-releasing hormone receptor
-
SASAKI S, CHO N, NARA Y et al.: Discovery of a thieno [2,3-d] pyrimidine-2.4-dione bearing a p-methoxyureidophenyl moiety at the position 6: a highly potent and orally bioavailable non-peptide antagonist for human luteinising hormone-releasing hormone receptor. J. Med. Chem. (2003) 46:113-124.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 113-124
-
-
Sasaki, S.1
Cho, N.2
Nara, Y.3
-
8
-
-
0038021571
-
Suppression of a pituitary-ovarian axis by chronic oral administration of a novel non-peptide gonadotriphin-releasing hormone antagonist, TAK-013, in cynomolgus monkeys
-
HARA T, ARAKI H, KUSAKA M et al.: Suppression of a pituitary-ovarian axis by chronic oral administration of a novel non-peptide gonadotriphin-releasing hormone antagonist, TAK-013, in cynomolgus monkeys. J. Clin. Endocrinol. Metab. (2003) 88:1697-1704.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 1697-1704
-
-
Hara, T.1
Araki, H.2
Kusaka, M.3
-
9
-
-
1242336514
-
Effect of single dose of TAK-013, a new non-peptide orally active gonadotrophin-releasing hormone antagonist, in healthy young men
-
CLARK E, BOYCE M, WARRINGTON S et al.: Effect of single dose of TAK-013, a new non-peptide orally active gonadotrophin-releasing hormone antagonist, in healthy young men. Proc. Br. Pharmacol. Soc. Clin. Pharmacol. Section, Br. J Clin. Pharmacol. (2003) 55:443.
-
(2003)
Proc. Br. Pharmacol. Soc. Clin. Pharmacol. Section, Br. J Clin. Pharmacol.
, vol.55
, pp. 443
-
-
Clark, E.1
Boyce, M.2
Warrington, S.3
-
10
-
-
18444369293
-
A new class of potent non-peptide luteinising hormone-releasing hormone (LHRH) antagonists: Design and synthesis of 2-phenylimidazo [1,2-a] pyrimidin-5-ones
-
SASAKI S, IMAEDA T, HAYASE Y et al.: A new class of potent non-peptide luteinising hormone-releasing hormone (LHRH) antagonists: design and synthesis of 2-phenylimidazo [1,2-a] pyrimidin-5-ones. Bioorg. Med. Chem. Lett. (2002) 12:2073-2077.
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 2073-2077
-
-
Sasaki, S.1
Imaeda, T.2
Hayase, Y.3
-
11
-
-
0035833042
-
Potent non-peptide GnRH receptor antagonists derived from substituted indole-5-carboxamides and -acetamides bearing a pyridine side-chain terminus
-
ASHTON WT, SISCO RM, YANG YT et al.: Potent non-peptide GnRH receptor antagonists derived from substituted indole-5-carboxamides and -acetamides bearing a pyridine side-chain terminus. Bioorg. Med. Chem. Lett. (2001) 11:1727-1731.
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 1727-1731
-
-
Ashton, W.T.1
Sisco, R.M.2
Yang, Y.T.3
-
12
-
-
0037060924
-
2-Arylindoles as gonadotrophin releasing hormone (GnRH) antagonists: Optimisation of the tryptamine side chain
-
YOUNG JR, HUANG SX, WALSH TF et al.: 2-Arylindoles as gonadotrophin releasing hormone (GnRH) antagonists: optimisation of the tryptamine side chain. Bioorg. Med. Chem. Lett. (2002) 12:827-832.
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 827-832
-
-
Young, J.R.1
Huang, S.X.2
Walsh, T.F.3
-
13
-
-
17944383430
-
Orally bioavailable indole-based non-peptide GnRH receptor antagonists with high potency and functional activity
-
ASHTON WT, SISCO RM, KIECZYKOWSKI GR et al.: Orally bioavailable indole-based non-peptide GnRH receptor antagonists with high potency and functional activity. Bioorg. Med. Chem. Lett. (2001) 11:2597-2602.
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 2597-2602
-
-
Ashton, W.T.1
Sisco, R.M.2
Kieczykowski, G.R.3
-
14
-
-
0035833079
-
Substituted indole-5-carboxamides and -acetamides as potent non-peptide GnRH receptor antagonists
-
ASHTON WT, SISCO RM, YANG YT et al.: Substituted indole-5-carboxamides and -acetamides as potent non-peptide GnRH receptor antagonists. Bioorg. Med. Chem. Lett. (2001) 11:1723-1726.
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 1723-1726
-
-
Ashton, W.T.1
Sisco, R.M.2
Yang, Y.T.3
-
15
-
-
0034618152
-
Quinolones as gonadotrophin-releasing hormone (GnRH) antagonists: Simultaneous optimisation of the C(3)-aryl and C(6)-substituents
-
YOUNG JR, HUANG SX, CHEN I et al.: Quinolones as gonadotrophin-releasing hormone (GnRH) antagonists: simultaneous optimisation of the C(3)-aryl and C(6)-substituents. Bioorg. Med. Chem. Lett. (2000) 10:1723-1727.
-
(2000)
Bioorg. Med. Chem. Lett.
, vol.10
, pp. 1723-1727
-
-
Young, J.R.1
Huang, S.X.2
Chen, I.3
-
16
-
-
0035866652
-
1H]-quinolone antagonist for the gonadotrophin-releasing hormone receptor
-
1H]-quinolone antagonist for the gonadotrophin-releasing hormone receptor. J. Med. Chem. (2001) 44:917-922.
-
(2001)
J. Med. Chem.
, vol.44
, pp. 917-922
-
-
Devita, R.J.1
Walsh, T.F.2
Young, J.R.3
-
17
-
-
18244406324
-
Initial structure-activity relationship studies of a novel series of pyrrolo [1,2-a] pyrimid-7-ones as GNRH receptor antagonists
-
ZHU YF, STRUTHERS RS, CONNORS PJ et al.: Initial structure-activity relationship studies of a novel series of pyrrolo [1,2-a] pyrimid-7-ones as GNRH receptor antagonists. Bioorg. Med. Chem. Lett. (2002) 12:399-402.
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 399-402
-
-
Zhu, Y.F.1
Struthers, R.S.2
Connors, P.J.3
-
18
-
-
0037464459
-
Design and structure-activity relationships of 2-alkyl-3-aminomethyl-6-(3-methoxyphenyl)-7-methyl-8-(2-fluorobenzyl imidazolo [1,2-a)pyrimid-5ones as potent GnRH receptor antagonists
-
ZHU YF, GUO Z, GROSS TD et al.: Design and structure-activity relationships of 2-alkyl-3-aminomethyl-6-(3-methoxyphenyl)-7-methyl-8-(2-fluorobenzyl imidazolo [1,2-a)pyrimid-5ones as potent GnRH receptor antagonists. J. Med. Chem. (2003) 46:1769-1772.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 1769-1772
-
-
Zhu, Y.F.1
Guo, Z.2
Gross, T.D.3
-
19
-
-
0038587497
-
Identification of 1-arylmethyl-3-(2-aminoethyl)-5-aryluracil as novel gonadotrophin-releasing hormone receptor antagonists
-
ZHU YF, GROSS TD, GUO Z et al.: Identification of 1-arylmethyl-3-(2-aminoethyl)-5-aryluracil as novel gonadotrophin-releasing hormone receptor antagonists. J. Med. Chem. (2003) 46:2023-2026.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 2023-2026
-
-
Zhu, Y.F.1
Gross, T.D.2
Guo, Z.3
-
20
-
-
10744221847
-
Synthesis and structure-activity relationships of 1-arylmethyl-3-(2-aminopropyl)-5-aryl-6-methyluracils as potent GnRH receptor antagonists
-
GUO Z, ZHU YF, TUCCI FC et al.: Synthesis and structure-activity relationships of 1-arylmethyl-3-(2-aminopropyl)-5-aryl-6-methyluracils as potent GnRH receptor antagonists. Bioorg. Med. Chem. Lett. (2003) 13:3311-3315.
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 3311-3315
-
-
Guo, Z.1
Zhu, Y.F.2
Tucci, F.C.3
-
21
-
-
18644378190
-
The discovery of novel small molecule non-peptide gonadotrophin-releasing hormone (GnRH) receptor antagonists
-
LUTHIN DR, HONG Y, PATHAK VP et al.: The discovery of novel small molecule non-peptide gonadotrophin-releasing hormone (GnRH) receptor antagonists. Bioorg. Med. Chem. Lett. (2002) 12:3467-3470.
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 3467-3470
-
-
Luthin, D.R.1
Hong, Y.2
Pathak, V.P.3
-
22
-
-
18744366904
-
Characterization of mono- and diaminopyrimidine derivatives as novel, non-peptide gonadotrophin-releasing hormone (GnRH) receptor antagonists
-
LUTHIN DR, HONG Y, TOMPKINS E et al.: Characterization of mono- and diaminopyrimidine derivatives as novel, non-peptide gonadotrophin-releasing hormone (GnRH) receptor antagonists. Bioorg. Med. Chem. Lett. (2002) 12:3635-3639.
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 3635-3639
-
-
Luthin, D.R.1
Hong, Y.2
Tompkins, E.3
-
23
-
-
0037405120
-
Biological characterization of a novel, orally active small molecule gonadotrophin-releasing hormone (GnRH) antagonist using castrated and intact rats
-
ANDERES KL, LUTHIN DR, CASTILLO R et al.: Biological characterization of a novel, orally active small molecule gonadotrophin-releasing hormone (GnRH) antagonist using castrated and intact rats. J. Pharma. Exp. Therap. (2003) 305:688-695.
-
(2003)
J. Pharma. Exp. Therap.
, vol.305
, pp. 688-695
-
-
Anderes, K.L.1
Luthin, D.R.2
Castillo, R.3
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