Synthesis and structure-activity relationships of 1-arylmethyl-3-(2-aminopropyl)-5-aryl-6-methyluracils as potent GnRH receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 19, 2003, Pages 3311-3315

  Guo, Zhiqiang ^a   Zhu, Yun Fei ^a   Tucci, Fabio C ^a   Gao, Yinghong ^a   Struthers, R Scott ^a   Saunders, John ^a   Gross, Timothy D ^a   Xie, Qiu ^a   Reinhart, Greg J ^a   Chen, Chen ^a  

^a NEUROCRINE BIOSCIENCES INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GONADORELIN; GONADORELIN RECEPTOR; METHYL GROUP; RECEPTOR BLOCKING AGENT; URACIL; URACIL DERIVATIVE;

ARTICLE; BINDING AFFINITY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

EID: 10744221847     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00620-6     Document Type: Article

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