-
1
-
-
0025739613
-
Differential regulation of primitive human hematopoietic cells in long-term cultures maintained on genetically engineered murine stromal cells
-
Sutherland HJ, Eaves CJ, Lansdorp PM, Thacker JD, Hogge DE: Differential regulation of primitive human hematopoietic cells in long-term cultures maintained on genetically engineered murine stromal cells. Blood 78:666, 1991
-
(1991)
Blood
, vol.78
, pp. 666
-
-
Sutherland, H.J.1
Eaves, C.J.2
Lansdorp, P.M.3
Thacker, J.D.4
Hogge, D.E.5
-
2
-
-
0019444293
-
Human granulocytes generated in continuous bone marrow culture are physiologically normal
-
Greenberg HM, Newburger PE, Parker LM, Novak T, Greenberger JS: Human granulocytes generated in continuous bone marrow culture are physiologically normal. Blood 58:724, 1981
-
(1981)
Blood
, vol.58
, pp. 724
-
-
Greenberg, H.M.1
Newburger, P.E.2
Parker, L.M.3
Novak, T.4
Greenberger, J.S.5
-
3
-
-
0019051838
-
Long-term culture of human bone marrow cells
-
Gartner S, Kaplan HS: Long-term culture of human bone marrow cells. Proc Natl Acad Sci USA 77:4756, 1980
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 4756
-
-
Gartner, S.1
Kaplan, H.S.2
-
4
-
-
0020639615
-
Enzymatic treatment of long-term human marrow cultures reveals the preferential location of primitive hemopoietic progenitors in the adherent layer
-
Coulombel L, Eaves AC, Eaves CJ: Enzymatic treatment of long-term human marrow cultures reveals the preferential location of primitive hemopoietic progenitors in the adherent layer. Blood 62:291, 1983
-
(1983)
Blood
, vol.62
, pp. 291
-
-
Coulombel, L.1
Eaves, A.C.2
Eaves, C.J.3
-
5
-
-
0027466339
-
Alternative mechanisms with and without Steel factor support primitive human hematopoiesis
-
Sutherland HJ, Hogge DE, Cook D, Eaves CJ: Alternative mechanisms with and without Steel factor support primitive human hematopoiesis. Blood 81:1465, 1993
-
(1993)
Blood
, vol.81
, pp. 1465
-
-
Sutherland, H.J.1
Hogge, D.E.2
Cook, D.3
Eaves, C.J.4
-
6
-
-
0028963195
-
Functionally distinct human marrow stromal cell lines immortalized by transduction with the human papilloma virus E6/E7 genes
-
Roecklein BA, Torok-Storb B: Functionally distinct human marrow stromal cell lines immortalized by transduction with the human papilloma virus E6/E7 genes. Blood 85:997, 1995
-
(1995)
Blood
, vol.85
, pp. 997
-
-
Roecklein, B.A.1
Torok-Storb, B.2
-
7
-
-
0025880646
-
Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. II. Analysis of positive and negative regulators produced by stromal cells within the adherent layer
-
Eaves CJ, Cashman JD, Kay RJ, Dougherty GJ, Otsuka T, Gaboury LA, Hogge DE, Lansdorp PM, Eaves AC, Humphries RK: Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. II. Analysis of positive and negative regulators produced by stromal cells within the adherent layer. Blood 78:110, 1991
-
(1991)
Blood
, vol.78
, pp. 110
-
-
Eaves, C.J.1
Cashman, J.D.2
Kay, R.J.3
Dougherty, G.J.4
Otsuka, T.5
Gaboury, L.A.6
Hogge, D.E.7
Lansdorp, P.M.8
Eaves, A.C.9
Humphries, R.K.10
-
8
-
-
0026505736
-
Long-term erythropoiesis from constant numbers of CD34+ cells in serum-free cultures initiated with highly purified progenitor cells from human bone marrow
-
Lansdorp PM, Dragowska W: Long-term erythropoiesis from constant numbers of CD34+ cells in serum-free cultures initiated with highly purified progenitor cells from human bone marrow. J Exp Med 175:1501, 1992
-
(1992)
J Exp Med
, vol.175
, pp. 1501
-
-
Lansdorp, P.M.1
Dragowska, W.2
-
9
-
-
0029976140
-
Self-renewal of primitive human hematopoietic cells (long-term-culture-initiating cells) in vitro and their expansion in defined medium
-
Petzer AL, Hogge DE, Lansdorp PM, Reid DS, Eaves CJ: Self-renewal of primitive human hematopoietic cells (long-term-culture-initiating cells) in vitro and their expansion in defined medium. Proc Natl Acad Sci USA 93:1470, 1996
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1470
-
-
Petzer, A.L.1
Hogge, D.E.2
Lansdorp, P.M.3
Reid, D.S.4
Eaves, C.J.5
-
11
-
-
0024362725
-
Clonal hematopoiesis demonstrated by X-linked DNA polymorphisms after allogeneic bone marrow transplantation
-
Turhan AG, Humphries RK, Phillips GL, Eaves AC, Eaves CJ: Clonal hematopoiesis demonstrated by X-linked DNA polymorphisms after allogeneic bone marrow transplantation. N Engl J Med 320:1655, 1989
-
(1989)
N Engl J Med
, vol.320
, pp. 1655
-
-
Turhan, A.G.1
Humphries, R.K.2
Phillips, G.L.3
Eaves, A.C.4
Eaves, C.J.5
-
12
-
-
0026650764
-
Direct contact between human primitive hematopoietic progenitors and bone marrow stroma is not required for long-term in vitro hematopoiesis
-
Verfaillie CM: Direct contact between human primitive hematopoietic progenitors and bone marrow stroma is not required for long-term in vitro hematopoiesis. Blood 79:2821, 1992
-
(1992)
Blood
, vol.79
, pp. 2821
-
-
Verfaillie, C.M.1
-
13
-
-
0028037626
-
Expansion of hematopoietic progenitor cell populations in stirred suspension bioreactors of normal human bone marrow cells
-
Zandstra PW, Eaves CJ, Piret JM: Expansion of hematopoietic progenitor cell populations in stirred suspension bioreactors of normal human bone marrow cells. Biotechnology 12:909, 1994
-
(1994)
Biotechnology
, vol.12
, pp. 909
-
-
Zandstra, P.W.1
Eaves, C.J.2
Piret, J.M.3
-
14
-
-
0028079924
-
+ subpopulations of human bone marrow cells
-
+ subpopulations of human bone marrow cells. Proc Natl Acad Sci USA 91:12223, 1994
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12223
-
-
Sauvageau, G.1
Lansdorp, P.M.2
Eaves, C.J.3
Hogge, D.E.4
Dragowska, W.H.5
Reid, D.S.6
Largman, C.7
Lawrence, H.J.8
Humphries, R.K.9
-
15
-
-
0025771278
-
Differential effects of microenvironmentally presented interleukin 3 versus soluble growth factor on primitive human hematopoietic cells
-
Otsuka T, Thacker JD, Eaves CJ, Hogge DE: Differential effects of microenvironmentally presented interleukin 3 versus soluble growth factor on primitive human hematopoietic cells. J Clin Invest 88:417, 1991
-
(1991)
J Clin Invest
, vol.88
, pp. 417
-
-
Otsuka, T.1
Thacker, J.D.2
Eaves, C.J.3
Hogge, D.E.4
-
17
-
-
0023677508
-
Partial characterization of a novel stromal cell-derived pre-B-cell growth factor active on normal and immortalized pre-B cells
-
Lemoine FM, Humphries RK, Abraham SDM, Krystal G, Eaves CJ: Partial characterization of a novel stromal cell-derived pre-B-cell growth factor active on normal and immortalized pre-B cells. Exp Hematol 16:718, 1988
-
(1988)
Exp Hematol
, vol.16
, pp. 718
-
-
Lemoine, F.M.1
Humphries, R.K.2
Abraham, S.D.M.3
Krystal, G.4
Eaves, C.J.5
-
18
-
-
0023102883
-
A stromal cell line from myeloid longterm bone marrow cultures can support myelopoiesis and B lymphopoiesis
-
Collins LS, Dorshkind K: A stromal cell line from myeloid longterm bone marrow cultures can support myelopoiesis and B lymphopoiesis. J Immunol 138:1082, 1987
-
(1987)
J Immunol
, vol.138
, pp. 1082
-
-
Collins, L.S.1
Dorshkind, K.2
-
19
-
-
0027531528
-
1 null mutation in mice causes excessive inflammatory response and early death
-
1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci USA 90:770, 1993
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 770
-
-
Kulkarni, A.B.1
Huh, C.-G.2
Becker, D.3
Geiser, A.4
Lyght, M.5
Flanders, K.C.6
Roberts, A.B.7
Sporn, M.B.8
Ward, J.M.9
Karlsson, S.10
-
20
-
-
0026766250
-
Retroviral gene transfer to primitive normal and leukemic hematopoietic cells using clinically applicable procedures
-
Hughes PFD, Thacker JD, Hogge D, Sutherland HJ, Thomas TE, Lansdorp PM, Eaves CJ, Humphries RK: Retroviral gene transfer to primitive normal and leukemic hematopoietic cells using clinically applicable procedures. J Clin Invest 89:1817, 1992
-
(1992)
J Clin Invest
, vol.89
, pp. 1817
-
-
Hughes, P.F.D.1
Thacker, J.D.2
Hogge, D.3
Sutherland, H.J.4
Thomas, T.E.5
Lansdorp, P.M.6
Eaves, C.J.7
Humphries, R.K.8
-
21
-
-
0025990964
-
The effects of interleukin 6 and interleukin 3 on early hematopoietic events in long-term cultures of human marrow
-
Otsuka T, Thacker JD, Hogge DE: The effects of interleukin 6 and interleukin 3 on early hematopoietic events in long-term cultures of human marrow. Exp Hematol 19:1042, 1991
-
(1991)
Exp Hematol
, vol.19
, pp. 1042
-
-
Otsuka, T.1
Thacker, J.D.2
Hogge, D.E.3
-
22
-
-
0025853454
-
Dominant positive and negative selection using a hygromycin phosphotransferase-thymidine kinase fusion gene
-
Lupton SD, Brunton LL, Kalbert VA, Overell RW: Dominant positive and negative selection using a hygromycin phosphotransferase-thymidine kinase fusion gene. Mol Cell Biol 11:3374, 1991
-
(1991)
Mol Cell Biol
, vol.11
, pp. 3374
-
-
Lupton, S.D.1
Brunton, L.L.2
Kalbert, V.A.3
Overell, R.W.4
-
23
-
-
0028035747
-
A modified indicator gene for selection of retrotransposition events in mammalian cells
-
Freeman JD, Goodchild NL, Mager DL: A modified indicator gene for selection of retrotransposition events in mammalian cells. Biotechniques 17:46, 1994
-
(1994)
Biotechniques
, vol.17
, pp. 46
-
-
Freeman, J.D.1
Goodchild, N.L.2
Mager, D.L.3
-
24
-
-
0026667401
-
Support of human hematopoiesis in long-term bone marrow cultures by murine stromal cells selectively expressing the membrane-bound and secreted forms of the human homolog of the steel factor
-
Toksoz D, Zsebo KM, Smith KA, Hu S, Brankow D, Suggs SV, Martin FH, Williams DA: Support of human hematopoiesis in long-term bone marrow cultures by murine stromal cells selectively expressing the membrane-bound and secreted forms of the human homolog of the steel factor. Proc Natl Acad Sci USA 89:7350, 1992
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7350
-
-
Toksoz, D.1
Zsebo, K.M.2
Smith, K.A.3
Hu, S.4
Brankow, D.5
Suggs, S.V.6
Martin, F.H.7
Williams, D.A.8
-
25
-
-
0023872192
-
Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors
-
Karasuyama H, Melchers F: Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors. Eur J Immunol 18:97, 1988
-
(1988)
Eur J Immunol
, vol.18
, pp. 97
-
-
Karasuyama, H.1
Melchers, F.2
-
26
-
-
0023871422
-
A safe packaging line for gene transfer: Separating viral genes on two different plasmids
-
Markowitz D, Goff S, Bank A: A safe packaging line for gene transfer: Separating viral genes on two different plasmids. J Virol 62:1120, 1988
-
(1988)
J Virol
, vol.62
, pp. 1120
-
-
Markowitz, D.1
Goff, S.2
Bank, A.3
-
27
-
-
0025297090
-
Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers
-
Sutherland HJ, Lansdorp PM, Henkelman DH, Eaves AC, Eaves CJ: Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers. Proc Natl Acad Sci USA 87:3584, 1990
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 3584
-
-
Sutherland, H.J.1
Lansdorp, P.M.2
Henkelman, D.H.3
Eaves, A.C.4
Eaves, C.J.5
-
28
-
-
0027531374
-
Maintenance of high levels of pluripotent hematopoietic stem cells in vitro: Effect of stromal cells and c-kit
-
Wineman JP, Nishikawa SI, Muller-Sieburg CE: Maintenance of high levels of pluripotent hematopoietic stem cells in vitro: Effect of stromal cells and c-kit. Blood 81:365, 1993
-
(1993)
Blood
, vol.81
, pp. 365
-
-
Wineman, J.P.1
Nishikawa, S.I.2
Muller-Sieburg, C.E.3
-
29
-
-
0028047342
-
Identification and mutation of primary and secondary proteolytic cleavage sites in murine stem cell factor cDNA yields biologically active, cell-associated protein
-
Majumdar MK, Feng L, Medlock E, Toksoz D, Williams DA: Identification and mutation of primary and secondary proteolytic cleavage sites in murine stem cell factor cDNA yields biologically active, cell-associated protein. J Biol Chem 269:1237, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 1237
-
-
Majumdar, M.K.1
Feng, L.2
Medlock, E.3
Toksoz, D.4
Williams, D.A.5
-
30
-
-
0025030443
-
Expansion in vitro of retrovirally marked totipotent hematopoietic stem cells
-
Fraser CC, Eaves CJ, Szilvassy SJ, Humphries RK: Expansion in vitro of retrovirally marked totipotent hematopoietic stem cells. Blood 76:1071, 1990
-
(1990)
Blood
, vol.76
, pp. 1071
-
-
Fraser, C.C.1
Eaves, C.J.2
Szilvassy, S.J.3
Humphries, R.K.4
-
31
-
-
0029151176
-
Characterization and purification of a primitive hematopoietic cell type in adult mouse marrow capable of lympho-myeloid differentiation in long-term marrow "switch" cultures
-
Lemieux ME, Rebel VI, Lansdorp PM, Eaves CJ: Characterization and purification of a primitive hematopoietic cell type in adult mouse marrow capable of lympho-myeloid differentiation in long-term marrow "switch" cultures. Blood 86:1339, 1995
-
(1995)
Blood
, vol.86
, pp. 1339
-
-
Lemieux, M.E.1
Rebel, V.I.2
Lansdorp, P.M.3
Eaves, C.J.4
-
32
-
-
0345002649
-
Long-term oligoclonal hematopoiesis after transplantation of culture-purged autologous bone marrow in chronic myeloid leukemia (CML)
-
abstr
-
Eaves CJ, Shaw G, Horsman D, Barnett MJ, Eaves AC: Long-term oligoclonal hematopoiesis after transplantation of culture-purged autologous bone marrow in chronic myeloid leukemia (CML). Blood 80:67a, 1992 (abstr, suppl 1)
-
(1992)
Blood
, vol.80
, Issue.1 SUPPL.
-
-
Eaves, C.J.1
Shaw, G.2
Horsman, D.3
Barnett, M.J.4
Eaves, A.C.5
-
33
-
-
0029161434
-
A novel single-cell proliferation assay shows that long-term culture-initiating cell (LTC-IC) maintenance over time results from the extensive proliferation of a small fraction of LTC-IC
-
Verfaillie CM, Miller JS: A novel single-cell proliferation assay shows that long-term culture-initiating cell (LTC-IC) maintenance over time results from the extensive proliferation of a small fraction of LTC-IC. Blood 86:2137, 1995
-
(1995)
Blood
, vol.86
, pp. 2137
-
-
Verfaillie, C.M.1
Miller, J.S.2
-
34
-
-
0027162426
-
Large-scale expansion of human stem and progenitor cells from bone marrow mononuclear cells in continuous perfusion cultures
-
Koller MR, Emerson SG, Palsson BO: Large-scale expansion of human stem and progenitor cells from bone marrow mononuclear cells in continuous perfusion cultures. Blood 82:378, 1993
-
(1993)
Blood
, vol.82
, pp. 378
-
-
Koller, M.R.1
Emerson, S.G.2
Palsson, B.O.3
-
35
-
-
1842402963
-
Very high concentrations of cytokines are required for the maximal stimulation in vitro of primitive human hematopoietic progenitors (LTC-IC) and are depleted most rapidly by subpopulations of cells that are highly enriched in their LTC-IC content
-
abstr
-
Zandstra PW, Petzer AL, Eaves CJ, Piret JM: Very high concentrations of cytokines are required for the maximal stimulation in vitro of primitive human hematopoietic progenitors (LTC-IC) and are depleted most rapidly by subpopulations of cells that are highly enriched in their LTC-IC content. Blood 86:422a, 1995 (abstr, suppl 1)
-
(1995)
Blood
, vol.86
, Issue.1 SUPPL.
-
-
Zandstra, P.W.1
Petzer, A.L.2
Eaves, C.J.3
Piret, J.M.4
-
37
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
Gossen M, Bujard H: Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 89:5547, 1992
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 5547
-
-
Gossen, M.1
Bujard, H.2
|