Circulating cytokines response and the level of erythropoiesis in sickle cell anemia

American Journal of Hematology

Volumn 60, Issue 2, 1999, Pages 105-115

  Croizat, Helena ^a   Nagel, Ronald L ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Fetal hemoglobin; Hematopoiesis; Steel factor; TGF ; Transferrin receptor

Indexed keywords

CD34 ANTIGEN; CYTOKINE; ERYTHROPOIETIN; GRANULOCYTE COLONY STIMULATING FACTOR; HEMOGLOBIN F; INTERLEUKIN 7; LEUKEMIA INHIBITORY FACTOR; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; STEM CELL FACTOR; TRANSFERRIN RECEPTOR; TRANSFORMING GROWTH FACTOR BETA;

ADULT; ARTICLE; BURST FORMING UNIT E; CONTROLLED STUDY; CYTOKINE RELEASE; ERYTHROPOIESIS; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SICKLE CELL ANEMIA;

ADULT; ANEMIA, SICKLE CELL; ANTIGENS, CD34; CYTOKINES; ERYTHROCYTES; ERYTHROPOIESIS; ERYTHROPOIETIN; FETAL HEMOGLOBIN; GRANULOCYTE COLONY-STIMULATING FACTOR; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INTERLEUKIN-3; INTERLEUKIN-7; KINETICS; MIDDLE AGED; RECEPTORS, TRANSFERRIN; SOLUBILITY; STEM CELL FACTOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 0032952491     PISSN: 03618609     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8652(199902)60:2<105::AID-AJH4>3.0.CO;2-Z     Document Type: Article

References (60)

1. Croizat H, Billet HH, Nagel RL. Heterogeneity in the properties of burst-forming units of erythroid lineage in sickle cell anemia: DNA synthesis and burst-promoting activity production are related to peripheral hemoglobin F levels. Blood 1990;75:1006.
2. Croizat H. Circulating cytokines in SS patients during steady state. Br J Haematol 1994;87:592.
3. Croizat H. Increased Plasma levels of steel factor in sickle cell anemia and its relationship to erythropoietic stress [abstract]. Blood 1994;84:119a.
4. Croizat H, Eaves CJ. Mobilization of early hematopoietic progenitors in patients with sickle cell disease [abstract]. The Clinical Research Meeting; 1995 May 5-8; San Diego, CA.
5. Croizat H, Nagel RL. Inhomogeneity of the circulating BFU-E regulation in sickle cell anemia: accessory cells properties and BFU-E growth factor response pattern. Br J Haematol 1993;84:481.
6. Nagel RL, Fabry ME. The many pathophysiologies of sickle cell anemia. Am J Hematol 1985;20:195.
7. Shin YJ, Baynes RD, Hudson BG, Flowers CH, Skikne BS, Cook JD. Serum transferrin receptor is a truncated form of tissue receptor. J Biol Chem 1990;265:19077.
8. Beguin Y, Heubers HA, Josephson B, Finch CA. Transferrin receptors in rat plasma. Proc Natl Acad Sci USA 1988;85:637.
9. Cook JD, Skikne BS, Baynes RD. Serum transferrin receptors. Ann Rev Med 1993;44:63.
10. Thorstensen K, Romslo I. The transferrin receptor: its diagnostic value and its potential as therapeutic target. Scand J Lab Invest 1993;53:113.
11. Klausner RD, Rouault TA, Harford JB. Regulating the fate of mRNA: the control of cellular iron metabolism. Cell 1993;72:19.
12. Huebers HA, Beguin Y, Pootrakul P, Einspahr D, Finch CA. Intact transferrin receptors in human plasma and their relation to erythropoiesis. Blood 1990;75:102.
13. Yarden Y, Kuang WJ, Yang-Feng T, Coussens L, Munemitsu S, Dull TJ, Chen E, Schlessinger J, Franke U, Ullrich A. Human protooncogene c-kit, a new cell surface receptor tyrosine kinase for an unidentified ligand. Eur Mol Biol Organ J 1987;6:3341.
14. Matsui Y, Zsebo KM, Hogan BL. Embryonic expression of a haematopoietic growth factor encoded by the S1 locus and the ligand for c-kit. Nature 1990;347:667.
15. Brannan CI, Lyman SD, Williams DE, Eisenman J, Anderson DM, Cosman D, Bedell MA, Jenkins NA, Copeland NG. Steel-Dickie mutation encodes a c-kit ligand lacking transmembrane and cytoplasmic domains. Proc Natl Acad Sci USA 1991;88:4671.
16. Flanagan JG, Chan DC, Leder P. Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the Sld mutant. Cell 1991;64:1025.
17. - cells cultured with interleukin-3, granulocyte colony-stimulating factor, or granulocyte-macrophage colony-stimulating factor. Blood 1991;77:2316.
18. Broxmeyer HE, Cooper S, Lu L, Hangoc G, Anderson D, Cosman D, Lyman SD, Williams DE. Effect of murine mast cell growth factor (c-kit proto-oncogene ligand) on colony formation by human marrow hematopoietic progenitor cells. Blood 1991;77:2142.
19. Broxmeyer HE, Hangoc G, Cooper S, Anderson D, Cosman D, Lyman SD, Williams DE. Influence of murine mast cell growth factor (c-kit ligand) on colony formation by mouse marrow hematopoietic progenitor cells. Exp Hematol 1991;19:143.
20. Metcalf D, Nicola NA. Direct proliferative actions of stem cell factor on murine bone marrow cells in vitro: effects of combination with colony-stimulating factors. Proc Natl Acad Sci USA 1991;88:6239.
21. Tsuji K, Zsebo KM, Ogawa M. Murine mast cell colony formation supported by IL-3, IL-4. and recombinant rat stem cell factor, ligand or c-kit. J Cell Physiol 1991;148:362.
22. Olivieri NF, Grunberger T, Ben-David Y, Ng J, Williams DE, Lyman S, Anderson DM, Axelrad AA, Correa P, Bernstein A, Freedman MH. Diamond-Blackfan anemia: heterogeneous response of hematopoietic progenitor cells in vitro to the protein product of the Steel locus. Blood 1991;78:2211.
23. Abkowitz JL, Sabo KM, Nakamoto B, Blau CA, Martin FH, Zsebo KM, Papayannopoulou T. Diamond-Blackfan anemia: in vitro response of erythroid progenitors to the ligand for c-kit. Blood 1991;78: 2198.
24. + hematopoietic progenitors in Diamond-Blackfan anemia. Blood 1991;78:2203.
25. Wodnar-Filipowicz A, Tichelli A, Zsebo KM, Speck B, Nissen C. Stem cell factor stimulates the in vitro growth of bone marrow cells from aplastic patients. Blood 1992;79:3196.
26. Bagnara CP, Strippoli P, Bonsi L, Brizzi MF, Avanzi GC, Timeus F, Ramenghi U, Piaggio G, Tong J, Podesta M, Paolucci G, Pegorarom L, Gabutti V, Bacigalupo A. Effect of stem cell factor on colony growth from acquired and constitutional (Fanconi) aplastic anemia. Blood 1992;80:382.
27. Wodnar-Filipowicz A, Yancik S, Moser Y, dalle Carbonare V, Gratwohl A, Tichelli A, Speck B, Nissen C. Levels of soluble stem cell factor in patients with aplastic anemia. Blood 1993;81:3259.
28. Broudy VC, Lin NL, Pristley GV, Nocka K, Wolf NS. Interaction of stem cell factor and its receptor c-kit mediates lodgement and acute expansion of hematopoietic cells in the murine spleen. Blood 1996; 88:75.
29. Roberts AB, Anzano MA, Wakefield LM, Roche NS, Stern DF, Sporn MB. Type beta transforming growth factor: a bifunctional regulator of cellular growth. Proc Natl Acad Sci USA 1985;82:119.
30. Hayashi SI, Gimble JM, Henley A, Ellingsworth LR, Kincade PW. Differential effects of TGF-β1 on lymphohemopoiesis in long-term bone marrow cultures. Blood 1989;74:1711.
31. Eaves CJ, Sutherland HJ, Cashman JD, Otsuka T, Lansdorp PM, Humphries RK, Eaves AC, Hogge DE. Regulation of primitive human hematopoietic cells in long-term marrow culture. Semin Hematol 1991;28:126.
32. Ruscetti FW, Jacobsen SEW, Dubois CM, Hestdal K, Keller JR. Hematopoietic cell growth is regulated by a balance of positive and negative regulators: potential role for receptor modulation. In: The negative regulation of hematopoiesis. Guigon M, Lemoine FM. Daniak N, Schechter A, Najman A, editors. Paris: Colloque INSERM/ John Libbey Eurotext Ldt.; 1993. 229:23.
33. Souza LM, Boone TC, Gabrilove J, Lai PH, Zsebo KM, Murdock DC, Chazin VR, Bruszewski J, Lu H, Chen KK, Barendt J, Platzer E, Moore MAS, Mertelsmann R, Welte K. Recombinant human granulocyte colony-stimulating factor: effects on normal and leukemic myeloid cells. Science 1986;232:61.
34. Metcalf D, Nicola NA. Proliferative effects of purified granulocyte colony-stimulating factor (G-CSF) on normal mouse hemopoietic cells. J Cell Physiol 1983;116:198.
35. Shirafuji N, Asano S, Matsuda S, Watari K, Takaku F, Nagata S. A new bioassay for human granulocyte colony-stimulating factor (hG-CSF) using murine myeloblastic NFS-60 cells as targets and estimation of its levels in sera from normal healthy persons and patients with infectious and hematological disorders. Exp Hematol 1989;17:116.
36. Watari K, Asano S, Shirafuji N, Kodo H, Ozawa K, Takaku F, Kamachi S. Serum granulocyte colony-stimulating factor levels in healthy volunteers and patients with various disorders as estimated by enzyme immunoassay. Blood 1989;73:117.
37. Darnia G, Komschlies KL, Faltynek CR, Ruscetti FW, Wiltrout RH. Administration of recombinant human interleukin-7 alters the frequency and number of myeloid progenitor cells in the bone marrow and spleen of mice. Blood 1992;79:1121.
38. Leary AG, Wong GG, Clark SC, Smith AG, Ogawa M. Leukemia inhibitory factor differentiation - inhibiting activity/human interleukin for DA cells augments proliferation of human hematopoietic stem cells. Blood 1990;75:1960.
39. Smith AG, Heath JK, Donaldson DD, Wong GG, Moreau J, Stahl M, Rogers D. Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature 1988;336:688.
40. Graham GJ, Wright EG, Hewick R, Wolpe SD, Wilkie NM, Donaldson D, Lorimore S, Pragnell IB. Identification and characterization of an inhibitor of haemopoietic stem cell proliferation. Nature 1990;344: 442.
41. Dunlop DJ, Wright EG, Lorimore S, Graham GJ, Holyoake T, Kerr DJ, Wolpe SD, Pragnell IB. Demonstration of stem cell inhibition and myeloprotective effects of SCl/rhMIPlα in vivo. Blood 1992;79:2221.
42. Molden DP, Alexander NM, Neeley WE. Fetal hemoglobin: optimum conditions for its estimation by alkali denaturation. Am J Clin Pathol 1982;77:568.
43. Croizat H, Nagel RE, Ponchio L, Eaves C. Characterization of primitive progenitors (LTC-IC) in the blood of patients with sickle cell disease. Blood 1996;88:497a.
44. Sherwood JB, Goldwasser E, Chilcote R, Carmichael LD, Nagel RL. Sickle cell anemia patients have low erythropoietic levels for their degree of anemia. Blood 1986;67:46.
45. Broudy VC, Lin NL, Priestley GV, Nocka K, Wolf NS. Interaction of stem cell factor and its receptor c-kit mediates lodgment and acute expansion of hematopoietic cells in the murine spleen. Blood 1996; 88:75.
46. - cells cultured with interleukin-3, granulocyte colony-stimulating factor, or granulocyte-macrophage colony-stimulating factor. Blood 1991;77:2316.
47. + cord blood cells in the presence of recombinant human stem cell factor. Blood 1992;79:2620.
48. + cells into the myeloid lineage. Blood 1992;80:1405.
49. Brandt J, Briddell RA, Srour EF, Leemhuis TB, Hoffman R. Role of c-kit ligand in the expansion of human hematopoietic progenitor cells. Blood 1992;79:634.
50. Leary AG, Zeng HQ, Clark SC, Ogawa M. Growth factor requirements for survival into and entry in to the cell cycle of primitive human hemopoietic progenitors. Proc Natl Acad Sci USA 1992;89:4013.
51. + cells. J Exp Med 1996;183:837.
52. McNiece IK, Langley KE, Zsebo KM. Recombinant human stem cell factor synergises with GM-CSF, G-CSF, IL-3 and epo to stimulate human progenitor cells of the myeloid and erythroid lineages. Exp Hematol 1991;19:226.
53. Williams N, Bertoncello I, Kavnoudias H, Zseho K, McNiece I. Recombinant rat stem cell factor stimulates the amplification and differentiation of fractionated mouse stem cell populations. Blood 1992;79: 58.
54. Carow CE, Hangoc G, Cooper SH, Williams DB, Broxmeyer HE. Mast cell growth factor (c-kit ligand) supports the growth of human multipotential progenitor cells with a high replating potential. Blood 1991;78:2216.
55. Fleming WH, Alpern EJ, Uchida N, Ikuta K, Weissman IL. Steel factor influences the distribution and activity of murine hematopoietic stem cells in vivo. Proc Natl Acad Sci USA 1993;90:3760.
56. + colony-forming cell types in blood and marrow of baboons. Blood 1992;80: 920.
57. Andrews RG, Bensinger WI, Knitter GH, Barthelmey SH, Longin K, Bernstein ID, Appelbaum FR, Zsebo KM. The ligand for c-kit, stem cell factor, stimulates the circulation of cells that engraft lethally irradiated baboons. Blood 1992;80:2715.
58. Peschle C, Gabbianelli M, Testa U, Pelosi E, Barbed T, Fossati C, Valtiere M, Leone L. C-kit ligand reactivates fetal hemoglobin synthesis in serum-free culture of stringently purified normal adult burst-forming unit-erythroid. Blood 1993;81:328.
59. Wodnar-Filipowicz A, Yancik S, Moser Y, dalle Carbonare V, Gratwohl A, Tichelli A, Speck B, Nissen C. Levels of soluble stem cell factor in serum of patients with aplastic anemia. Blood 1993;81:3259.
60. Bowen D, Yancik S, Bennett L, Culligan D, Kesser K. Serum stem cell factor concentration in patients with myelodisplastic syndromes. Br J Hematol 1993;85:63.