Characterization of human recombinant somatostatin sst5 receptors mediating activation of phosphoinositide metabolism

British Journal of Pharmacology

Volumn 121, Issue 1, 1997, Pages 91-96

  Wilkinson, Graeme F ^a   Feniuk, Wasyl ^a   Humphrey, Patrick P A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

BIM 23056; CHO K1 cells; Inositol phosphates; L 362,855; Somatostatin; sst5 receptor

Indexed keywords

BIM 23027; DEXTRO PHENYLALANYLPHENYLALANYLTYROSYL DEXTRO TRYPTOPHYLLYSYLVALYLPHENYLALANYL DEXTRO [3 (2 NAPHTHYL)ALANINAMIDE]; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL PHOSPHATE; L 362855; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITIDE; SOMATOSTATIN; SOMATOSTATIN RECEPTOR;

ANIMAL CELL; ARTICLE; CHO CELL; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL;

EID: 0030968052     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701116     Document Type: Article

References (33)

1. 2+ mobilization by cloned human somatostatin receptor subtypes 1 5, in transfected COS-7 cells. FEBS Lett., 348, 192 - 196.
2. BARBER, D.L., MCGUIRE, M.E. & GANZ, M.B. (1989). β-adrenergic and somatostatin receptors regulate Na-H exchange independent of cAMP. J. Biol. Chem., 264, 21038 - 21042.
3. CAMPS, M., CAROZZI, A., SCHNABEL, P., SCHEER, A., PARKER, P.J. & GIERSCHIK, P. (1992). Isozyme selective stimulation of phospholipase C-β2 by G-protein βγ subunits. Nature, 360, 684 - 686.
4. CHESSELL, I.P., BLACK, M.D., FENIUK, W. & HUMPHREY, P.P.A. (1996). Operational characteristics of somatostatin receptors mediating inhibitory actions on rat locus coeruleus neurones. Br. J. Pharmacol., 117, 1673 - 1678.
5. 1B-like receptor to increases in intracellular calcium through a pertussis toxin-sensitive mechanism in CHO-K1 cells. Br. J. Pharmacol., 116, 2889 - 2896.
6. 2 receptor-mediated activation of L-type calcium channels. J. Cardiovasc. Pharmacol., 26, 721 - 728.
7. 1B receptor on CHO cells: functional responses in the absence of radioligand binding. Br. J. Pharmacol., 117, 1119 - 1126.
8. HOYER, D., BELL, G.I., BERELOWITZ, M., EPELBAUM, J., FENIUK, W., HUMPHREY, P.P.A., O'CARROLL, A.-M., PATEL, Y.C., SCHONBRUNN, A., TAYLOR, J.E. & REISNE, T. (1995). Classification and nomenclature of somatostatin receptors. Trends Pharmacol. Sci., 16, 86 - 88.
9. 2-purinoceptor in CHO-K1 cells. Br. J. Pharmacol., 110, 1305 - 1310.
10. 1 adenosine receptor in CHO-K1 cells to calcium mobilisation via a pertussis toxin-sensitive mechanism. Br. J. Pharmacol., 111, 1252 - 1256.
11. JAKOBS, K.H., AKTORIES, K. & SCHULTZ, G. (1983). A nucleotide regulatory site for somatostatin inhibition of adenylate cyclase in S49 lymphoma cells. Nature, 303, 177 - 178.
12. JENKINSON, D.H., BARNARD, E.A., HOYER, D., HUMPHREY, P.P.A., LEFF, P. & SHANKLEY, N.P. (1995). International union of pharmacology committee on receptor nomenclature and drug classification. IX. Recommendations on terms and symbols in quantitative pharmacology. Pharmacol. Rev., 47, 255 - 266.
13. KLEUSS, C., SCHERUBL, H., HESCHELER, J., SCHULTZ, G. & WITTIG, B. (1992). Different β-subunits determine G-protein interaction with transmembrane receptors. Nature, 358, 424 - 426.
14. LEFF, P., DOUGALL, I.G. & HARPER, D. (1993). Estimation of partial agonist affinity by interaction with a full agonist: a direct operational model-fitting approach. Br. J. Pharmacol., 110, 239 - 244.
15. LEWIS, D.F., WEIGHT, F. & LUNI, A. (1986). A guanine nucleotide-binding protein mediating the inhibition of voltage-dependent calcium current by somatostatin in a pituitary cell line. Proc. Natl. Acad. Sci. U.S.A., 83, 9035 - 9039.
16. LIEBOW, C., REILLY, C., SERRANO, M. & SCHALLY, A. (1989). Somatostatin analogues inhibit growth of pancreatic cancer by stimulating tyrosine phosphatase. Proc. Natl. Acad. Sci. U.S.A., 86, 2003 - 2008.
17. LUTTRELL, L.M., VAN BIESEN, T., HAWES, B.E., KOCH, W.J., TOUHARA, K. & LEFKOWITZ, R.J. (1995). Gβγ subunits mediate mitogen-activated protein kinase activation by the tyrosine kinase insulin-like growth factor I receptor. J. Biol. Chem., 270, 16495 - 16498.
18. MCKEEN, E., FENIUK, W. & HUMPHREY, P.P.A. (1996). Somatostatin receptors mediating inhibition of basal and stimulated electrogenic ion transport in rat isolated distal mucosa. Naunyn-Schmiedeberg's Arch. Pharmacol., 352, 402 - 411.
19. 2+ concentration in cultured rat hippocampal neurones. Brain Res., 489, 361 - 364.
20. MUNOZ-ACEDO, G., IZQUIERDO-CLAROS, R.M., SANCHEZ-ALONSO, J.A., DEL-HOYO, N., PEREZ-ALBARSANZ, A. & ARILLA, E. (1995). Effect of somatostatin on the mass accumulation of inositol-1,4,5-trisphosphate in rat hypothalamus, striatum, frontoparietal cortex and hippocampus. Neurosci. Lett., 197, 41 - 44.
21. O'CARROLL, A.-M., RAYNOR, K., LOLAIT, S.J. & REISINE, T. (1994). Characterisation of cloned human somatostatin receptor SSTR5. Mol. Pharmacol., 46, 291 - 298.
22. RAYNOR, K., MURRAY, W.A., COY, D.H., TAYLOR, J.E., MOREAU, J.-P., YASUDA, K., BELL, G.I. & REISINE, T. (1993). Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides. Mol. Pharmacol., 43, 838 - 844.
23. SCHINDLER, M., HUMPHREY, P.P.A. & EMSON, P.C. (1996). Somatostatin receptors in the central nervous system. Prog. Neurobiol., 50, 9 - 47.
24. TOWNSEND-NICHOLSON, A. & SHINE, J. (1992). Molecular cloning and characterisation of a human brain A1 adenosine receptor cDNA. Brain Res. Mol. Brain Res., 16, 365 - 370.
25. 5 receptors expressed in CHO-K1 cells mediate increases in extracellular acidification by pertussis toxin-sensitive and -insensitive pathways. Br. J. Pharmacol., 117, 9P.
26. VAN BIESEN, T., HAWES, B.E., LUTTRELL, D.K., KRUEGER, K.M., TOUHARA, K., PORFIRI, E., SAKAUE, M., LUTTRELL, L.M. & LEFKOWITZ, R.J. (1995). Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway. Nature, 376, 781 - 784.
27. VIGUERIER, N., TAHIN-JOUTI, N., AYRAL, A.M., CAMBILLAN, C., SCEMAMA, J.L., BASTIE, M.J., KRUHTESEN, S., ESTERIE, J.P., PAYDAYROL, L., SUSINI, C. & VAYSSE, N. (1989). Direct inhibitory effects of a somatostatin analogue. SMS 201-955, on AR4-2J cell proliferation via a pertussis toxin-sensitive guanosine triphosphate-binding protein-independent mechanism. Endocrinology, 124, 1017 - 1025.
28. 5 receptor activation. Br. J. Pharmacol., 118, 25P.
29. 5 receptor. Br. J. Pharmacol., 118, 445 - 447.
30. 35S]thio)-triphosphate binding. Br. J. Pharmacol., 117, 10P.
31. 5 receptor couples to pertussis toxin-sensitive and -insensitive G-proteins. Br. J. Pharmacol., 119, 11P.
32. 2 by the α and βγ subunits of trimeric GTP-binding proteins. Proc. Natl. Acad. Sci. U.S.A., 90, 5297 - 5301.
33. YAMASHITA, N., SHIBUYA, N. & OGATA, E. (1987). Hyperpolarization of the membrane potential caused by somatostatin in dissociated human pituitary adenoma cells that secrete growth hormone. Proc. Natl. Acad. Sci. U.S.A., 83, 6198 - 6202.