Conservation and variation in superantigen structure and activity highlighted by the three-dimensional structures of two new superantigens from Streptococcus pyogenes

Journal of Molecular Biology

Volumn 299, Issue 1, 2000, Pages 157-168

  Arcus, Vickery L ^a,b   Proft, Thomas ^a,b   Sigrell, Jill A ^a,b   Baker, Heather M ^a,b   Fraser, John D ^a,b   Baker, Edward N ^a,b  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Crystal structures; Evolutionary variation; MHC class II binding; Streptococcal superantigens

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; STAPHYLOCOCCUS TOXIN; STREPTOCOCCUS ANTIGEN; T LYMPHOCYTE RECEPTOR; ZINC ION;

AMINO TERMINAL SEQUENCE; ANTIGEN BINDING; ANTIGENIC VARIATION; ARTICLE; BACTERIAL VIRULENCE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; IMMUNE RESPONSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; SEQUENCE HOMOLOGY; STREPTOCOCCUS PYOGENES; STRUCTURE ACTIVITY RELATION;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS; STREPTOCOCCUS PYOGENES;

EID: 0034716945     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.3725     Document Type: Article

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