High affinity T cell receptors from yeast display libraries block T cell activation by superantigens

Journal of Molecular Biology

Volumn 307, Issue 5, 2001, Pages 1305-1315

  Kieke, Michele C ^a   Sundberg, Eric ^b   Shusta, Eric V ^a   Mariuzza, Roy A ^b   Wittrup, K Dane ^c   Kranz, David M ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Antagonists; Directed evolution; Staphylococcus aureus; T cell activity; Yeast surface display

Indexed keywords

ENTEROTOXIN; HYBRID PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEIN AGA2P; STAPHYLOCOCCUS ENTEROTOXIN; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; BINDING AFFINITY; CELL INTERACTION; CELL SELECTION; CONTROLLED STUDY; CROSS REACTION; DNA LIBRARY; FLOW CYTOMETRY; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOSTIMULATION; INHIBITION KINETICS; LIGAND BINDING; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR AFFINITY; STAPHYLOCOCCUS AUREUS; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE RECEPTOR GENE;

STAPHYLOCOCCUS AUREUS;

EID: 0035853281     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4560     Document Type: Article

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