Delivery and expression of pDNA embedded in collagen matrices

Journal of Controlled Release

Volumn 95, Issue 2, 2004, Pages 309-320

  Cohen Sacks, Hagit ^a   Elazar, Victoria ^a   Gao, Jianchuan ^a   Golomb, Assaf ^a   Adwan, Hassan ^b   Korchov, Nikoly ^a   Levy, Robert J ^c   Berger, Martin R ^b   Golomb, Gershon ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

Collagen; Controlled release; Gene delivery; Gene therapy; Matrix; Non viral gene delivery; Restenosis

Indexed keywords

BIOCOMPATIBILITY; COLLAGEN; GENES; MUSCLE;

GENE THERAPY; LIPOSOMES;

DNA;

COLLAGEN; LIPOSOME; LUCIFERASE; NAKED DNA; PLASMID DNA; POLYETHYLENEIMINE; RECOMBINANT ENZYME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BALLOON; CAROTID ARTERY INJURY; CELL CULTURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG FORMULATION; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; GENETIC LINKAGE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMPLANTATION; MALE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; STATISTICAL SIGNIFICANCE;

EID: 1242271280     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2003.11.001     Document Type: Article

References (32)

1. Bonadio J. Tissue engineering via local gene delivery: update and future prospects for enhancing the technology. Adv. Drug Deliv. Rev. 44:2000;185-194.
2. Friess W. Collagen-biomaterial for drug delivery. Eur. J. Pharm. Biopharm. 45:1998;113-136.
3. Ochiya T., Takahama Y., Nagahara S., Sumita Y., Hidasa A., Iton H., Nagai Y., Terada M. New delivery system for plasmid DNA in vivo using atelocollagen as a carrier: the Minipellet. Nat. Med. 5:1999;707-710.
4. Bonadio J., Smiley E., Patil P., Goldstein S. Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration. Nat. Med. 5:1999;753-759.
5. Fang J., Zhu Y.Y., Smiley E., Bonadio J., Rouleau J.P., Goldstein S.A., McCauley L.K., Davidson B.L., Roessler B.J. Stimulation of new bone formation by direct transfer of osteogenic plasmid genes. Proc. Natl. Acad. Sci. USA. 93:1996;5753-5758.
6. Sheule R.K. The role of CpG motifs in immunostimulation and gene therapy. Adv. Drug Deliv. Rev. 44:2000;119-134.
7. Boussif O., Lezoualc'h F., Zanta M.A., Mergny M.D., Scherman D., Demeneix B., Behr J.P. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc. Natl. Acad. Sci. USA. 92:1995;7297-7301.
8. Wolfert M.A., Seymour L.W. Atomic force microscopic analysis of the influence of the molecular weight of poly (L) lysine on the size of polyelectrolyte complexes formed with DNA. Gene Ther. 3:1996;269-273.
9. Capan Y., Woo B.H., Gebrekidan S., Ahmed S., DeLuka P.P. Influence of formulation parameters on the characteristics of poly(D,L-lactide-co-glycolide) microspheres containing poly(L-lysine) complexed plasmid DNA. J. Control. Release. 60:1999;279-286.
10. Gao X., Huang L. Potentiation of cationic liposome-mediated gene delivery by polycations. Biochemistry. 35:1996;1027-1036.
11. Chonn A., Cullis P.R. Recent advances in liposome technologies and their applications for systemic gene delivery. Adv. Drug Deliv. Rev. 30:1998;73-83.
12. Colin W.P., Leonard W.S. Key issues in non-viral gene delivery. Adv. Drug Deliv. Rev. 34:1998;3-19.
13. Golomb G., Schoen F.J., Smith M., Linden J., Dixon M., Levy R.J. The role of glutaraldehyde induced crosslinks in calcification of bovine pericardium used in cardiac valve bioprostheses. Am. J. Pathol. 127:1987;122-130.
14. Fishbein I., Waltenberger J., Banai S., Rabinovich L., Chorny M., Levitzki A., Gazit A., Huber R., Mayr U., Gertz S.D., Golomb G. Local delivery of platelet-derived growth factor receptor-specific tyrphostin inhibits neointimal formation in rats. Arterioscler. Thromb. Vasc. Biol. 20:2000;667-676.
15. Cailleau R., Young R., Olive M., Reeves W.J. Jr. Breast tumor cell lines from pleural effusions. J. Natl. Cancer Inst. 53:1974;661-674.
16. Fishbein I., Chorny M., Gati I., Rabinovich L., Golomb G. Drug delivery systems for the treatment of restenosis. Wise D.L. Biomaterials and Bioengineering Handbook. 2000;313-335 Marcel Dekker, New York.
17. Fishbein I., Chorny M., Rabinovich L., Banai S., Gati I., Golomb G. Nanoparticulate delivery system of a tyrphostin for the treatment of restenosis. J. Control. Release. 65:2000;221-229.
18. Chorny M., Fishbein I., Golomb G. Drug delivery systems for the treatment of restenosis. Crit. Rev. Ther. Drug Carrier Syst. 17:2000;249-284.
19. Golomb G., Fishbein I., Banai S., Mishaly D., Moscovitz D., Gertz S.D., Gazit A., Poradosu E., Levitzki A. Controlled delivery of a tyrphostin inhibits intimal hyperplasia in a rat carotid artery injury model. Atherosclerosis. 125:1996;171-182.
20. Crystal R.G. Transfer of genes to humans: early lessons and obstacles to success. Science. 270:1995;404-410.
21. Birchall J.C., Marichal C., Campbell L., Alwan A., Hadgraft J., Gumbleton M. Gene expression in an intact ex vivo skin tissue model following percutaneous delivery of cationic liposome-plasmid DNA complexes. Int. J. Pharm. 197:2000;233-238.
22. Dani S.U. The challenge of vector development in gene therapy. Braz. J. Med. Biol. Res. 32:1999;133-145.
23. Mahato R.I., Smith L.C., Rolland A. Pharmaceutical perspectives of non-viral gene therapy. Adv. Genet. 41:1999;95-156.
24. Golomb G., Dixon M., Smith M.S., Schoen F.J., Levy R.J. Controlled-release drug delivery of diphosphonates to inhibit bioprosthetic heart valve calcification: release rate modulation with silicone matrices via drug solubility and membrane coating. J. Pharm. Sci. 76:1987;271-276.
25. Golomb G., Ezra V. Prevention of bioprosthetic heart valve tissue calcification by charge modification: effects of protamine binding by formaldehyde. J. Biomed. Mater. Res. 25:1991;85-98.
26. Cohen H., Alferiev I.S., Monkkonen J., Seibel M.J., Pinto T., Ezra A., Solomon V., Stepenski D., Sagi H., Ornoy A., Patlas N., Hagele G., Hoffman A., Breuer E., Golomb G. Synthesis and preclinical pharmacology of 2-(2-aminopyrimidino) ethylidene-1,1-bisphosphonic acid betaine(ISA-13-1) - a novel bisphosphonate. Pharm. Res. 16:1999;1401-1408.
27. Cohen H., Solomon V., Alferiev I.S., Breuer E., Ornoy A., Patlas N., Eidelman N., Hägele G., Golomb G. Bisphosphonates and tetracycline: experimental models for their evaluation in calcium-related disorders. Pharm. Res. 15:1998;606-613.
28. Bennett M.R., O'Sullivan M. Mechanisms of angioplasty and stent restenosis: implications for design of rational therapy. Pharmacol. Ther. 91:2001;149-166.
29. Wolff J.A., Ludtke J.J., Acsadi G., Williams P., Jani A. Long-term persistence of plasmid DNA and foreign gene expression in mouse muscle. Hum. Mol. Genet. 1:1992;363-369.
30. Wolff J.A., Malone R.W., Williams P., Chong W., Acsadi G., Jani A., Felgner P.L. Direct gene transfer into mouse muscle in vivo. Science. 247:1990;1465-1468.
31. Cohen H., Levy R.J., Gao J., Fishbein I., Kousaev V., Sosnowski S., Slomkowski S., Golomb G. Sustained delivery and expression of DNA encapsulated in polymeric nanoparticles. Gene Ther. 7:2000;1896-1905.
32. Cohen-Sacks H., Najajreh Y., Tchaikovski V., Gao G., Elazer V., Dahan R., Gati I., Kanaan M., Waltenberger J., Golomb G. Novel PDGFβR antisense encapsulated in polymeric nanospheres for the treatment of restenosis. Gene Ther. 9:2002;1607-1616.