Quantification of isomeric equilibria formed by metal ion complexes of 8-[2-(phosphonomethoxy)ethyl]-8-azaadenine (8,8aPMEA) and 9-[2- (phosphonomethoxy)ethyl]-8-azaadenine (9,8aPMEA). Derivatives of the antiviral nucleotide analogue 9-[2-(phosphonomethoxy) ethyl]adenine (PMEA)

Journal of Biological Inorganic Chemistry

Volumn 9, Issue 8, 2004, Pages 961-972

  Gómez Coca, Raquel B ^a   Kapinos, Larisa E ^a   Holý, Antonín ^b   Vilaplana, Rosario A ^c   González Vílchez, Francisco ^c   Sigel, Helmut ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^c UNIVERSITY OF SEVILLE   (Spain)

Author keywords

8 Azaadenines; Antivirals; Metal ion complexes; Nucleotide analogues; Stability constants

Indexed keywords

ACYCLIC NUCLEOSIDE; ADEFOVIR; ANTIVIRUS AGENT; BARIUM ION; CADMIUM; CALCIUM ION; CHELATE; COBALT; COPPER ION; LIGAND; MAGNESIUM ION; MANGANESE; METAL COMPLEX; METAL ION; NICKEL; NUCLEOTIDE DERIVATIVE; PHOSPHONIC ACID DERIVATIVE; STRONTIUM; ZINC ION;

ANTIVIRAL ACTIVITY; ARTICLE; CALCULATION; CHELATION; ISOMER; PH; POTENTIOMETRY; PRIORITY JOURNAL; TITRIMETRY;

ADENINE; ANTIVIRAL AGENTS; AZA COMPOUNDS; CALCIUM; CATIONS, DIVALENT; CHELATING AGENTS; COPPER; DRUG STABILITY; ETHERS; HYDROGEN-ION CONCENTRATION; ISOMERISM; KINETICS; LIGANDS; METALS; NUCLEOTIDES; ORGANOMETALLIC COMPOUNDS; PHOSPHONIC ACIDS; POTENTIOMETRY; ZINC;

EID: 12344281905     PISSN: 09498257     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00775-004-0591-7     Document Type: Article

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