A mouse fas-associated protein with homology to the human mortl/FADD protein is essential for fas-induced apoptosis

Molecular and Cellular Biology

Volumn 16, Issue 6, 1996, Pages 2756-2763

  Zhang, Jianke ^a   Winoto, Astar ^a,b  

^a University of California Berkeley   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ASSOCIATED PROTEIN; FAS CELL SURFACE RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; LYMPHOMA CELL LINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SEQUENCE HOMOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, CD95; APOPTOSIS; BASE SEQUENCE; CARRIER PROTEINS; CELL LINE; CLONING, MOLECULAR; DNA PRIMERS; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE; SPECIES SPECIFICITY;

EID: 0030001051     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.6.2756     Document Type: Article

References (55)

1. Beidler, D. R., M. Tewari, P. D. Friesen, G. Poirier, and V. M. Dixit. 1995. The baculovirus p35 protein inhibits Fas- and tumor necrosis factor-induced apoptosis. J. Biol. Chem. 270:16526-16528.
2. Bellgrau, D., D. Gold, H. Selawry, J. Moore, A. Franzusoff, and R. C. Duke. 1995. A role for CD95 ligand in preventing graft rejection. Nature (London) 377:630-632.
3. Boldin, M. P., E. E. Varfolomeev, Z. Pancer, I. L. Mett, J. H. Camonis, and D. Wallach. 1995. A novel protein that interacts with the death domain of fas/APO1 contains a sequence motif related to the death domain. J. Biol. Chem. 270:7795-7798.
4. Boyle, W. J., P. van der Geer, and T. Hunter. 1991. Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. Methods Enzymol. 201:110-149.
5. Brunner, T., R. Mogil, D. LaFace, N. J. Yoo, A. Mahboubi, F. Echeverri, S. J. Marin, W. R. Force, D. H. Lynch, C. F. Ware, and D. R. Green. 1995. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature (London) 373:441-444.
6. ink4. Mol. Cell. Biol. 15:2682-2688.
7. Chinnaiyan, A. M., K. O'Rourke, M. Tewari, and V. M. Dixit. 1995. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 81:505-512.
8. Cifone, M., R. De Maria, P. Roncaioli, M. R. Rippo, M. Azuma, L. L. Lanier, A. Santoni, and R. Testi. 1994. Apoptotic signaling through CD95 (Fas/ Apo-l) activates an acidic sphingomyelinase. J. Exp. Med. 180:1547-1552.
9. Cleveland, J. L., and J. N. Ihle. 1995. Contenders in FasL/TNF death signaling. Cell 81:479-482.
10. Cohen, J. J., R. C. Duke, V. A. Fadok, and K. S. Sellins. 1992. Apoptosis and programmed cell death in immunity. Annu. Rev. Immunol. 10:267-293.
11. Cohen, P. L., and R. A. Eisenberg. 1992. The Ipr and gld genes in systemic autoimmunity: life and death in the Fas lane. Immunol. Today 13:427-428.
12. Crispe, I. N. 1994. Fatal interactions: fas-induced apoptosis of mature T cells. Immunity 1:347-349.
13. Dhein, J., H. Walczac, C. Baumler, K.-M. Dabatin, and P. H. Krammer. 1995. Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature (London) 373:438-441.
14. Durfee, T., K. Becherer, P. L. Chen, S. H. Yen, Y. Yang, A. E. Kilburn, W. H. Lee, and S. J. Elledge. 1993. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev. 7:555-569.
15. Enari, M., H. Hug, and S. Nagata. 1995. Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature (London) 375:78-81.
16. Fisher, G. H., F. J. Rosenberg, S. E. Straus. J. K. Dale, L. A. Middleton, A. Y. Lin, W. Strober, M. J. Lenardo, and J. M. Puck. 1995. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 81:935-946.
17. Green, D. R., and D. W. Scotl. 1994. Activation-induced apoptosis in lymphocytes. Curr. Opin. Immunol. 6:476-487.
18. Griffith, T. S., T. Brunner, S. M. Fletcher, D. R. Green, and T. A. Ferguson. 1995. Fas ligand-induced apoptosis as a mechanism of immune privilege. Science 270:1189-1192.
19. Gulbins, E., R. Bissonnette, A. Mahboubi, S. Martin, W. Nishioka, T. Brunner, G. Baier, G. Baier-Bitterlich, C. Bytd, F. Lang, R. Kolesnick, A. Altman, and D. Green. 1995. Fas-induced apoptosis is mediated via a ceramide-initiated ras signaling pathway. Immunity 2:341-351.
20. Gunning, P., J. Leavitt, G. Muscat, S. Y. Ng, and L. Kedes. 1987. A human beta-actin expression vector system directs high-level accumulation of antisense transcripts. Proc. Natl. Acad. Sci. USA 84:4831-4835.
21. Hsu, H., H.-B. Shu, M.-G. Pan, and D. V. Goeddel. 1996. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 84:299-308.
22. Itoh, N., and S. Nagata. 1993. A novel protein domain required for apoptosis. J. Biol. Chem. 268:10932-10937.
23. Ju, S.-T., D. J. Panka, H. Cui, R. Ettinger, M. El-Khatib, D. H. Sherr, B. Z. Stanger, and A. Marshak-Rothstein. 1995. Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature (London) 373:444-448.
24. Kerr, J. F. R., and B. V. Harmon. 1991. Definition and incidence of apoptosis: an historical perspective, p. 5-29. In L. D. Tomei and F. O. Cope (ed.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
25. Kischkel, F. C., S. Hellbardt, I. Behrmann, M. Germer, M. Pawlita, P. H. Krammer, and M. E. Peter. 1995. Cytotoxicity-dependent APO-1 (Fas/ CD95) associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 14:5579-5588.
26. Korsmeyer, S. J. 1995. Regulators of cell death. Trends Genet. 11:101-105.
27. Krammer, P. H., J. Dhein, H. Walczak, I. Behrmann, S. Mariani, B. Matiba, M. Fath, P. T. Daniel, E. Knipping, M. O. Westendorp, et al. 1994. The role of APO-1-mediated apoptosis in the immune system. Immunol. Rev. 142:175-191.
28. Linette, G. P., and S. J. Korsmeyer. 1994. Differentiation and cell death: lessons from the immune system. Curr. Opin. Cell Biol. 6:809-815.
29. Los, M., M. Van de Craen, L. C. Penning, H. Schenk, M. Westendorp, P. A. Baeuerle, W. Droge, P. H. Krammer, W. Fiers, and O. K. Schulze. 1995. Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis. Nature (London) 375:81-83.
30. Luo, K., T. R. Hurley, and B. M. Sefton. 1991. Cyanogen bromide cleavage and proteolytic peptide mapping of proteins immobilized to membranes. Methods Enzymol. 201:149-152.
31. Martin, S. J., A. J. McGahon, W. K. Nishioka, D. LaFace, X. Guo, J. Th'ng, E. M. Bradbury, and D. R. Green. 1995. p34 cdc2 and apoptosis. Science 269:106-107.
32. Matthias, P., M. M. Muller, E. Schreiber, S. Rusconi, and W. Schaffner. 1989. Eukaryotic expression vectors for the analysis of mutant proteins. Nucleic Acids Res. 17:6418.
33. Mountz, J. D., T. Zhou, H. Bluethmann, J. Wu, and C. R. Edwards. 1994. Apoptosis defects analyzed in TcR transgenic and fas transgenic lpr mice. Int. Rev. Immunol. 11:321-342.
34. Nagata, S., and P. Golstein. 1995. The Fas death factor. Science 267:1449-1455.
35. Nishimura, Y., A. Ishii, Y. Kobayashi, Y. Yamasaki, and S. Yonehara. 1995. Expression and function of mouse Fas antigen on immature and mature T cells. J. Immunol. 154:4395-4403.
36. Ogasawara, J., T. Suda, and S. Nagata. 1995. Selective apoptosis of CD4 + CD8+ thymocytes by the anti-fas antibody. J. Exp. Med. 181:485-491.
37. Ogasawara, J., F. K. Watanabe, M. Adachi, A. Matsuzawa, T. Kasugai, Y. Kitamura, N. Itoh, T. Suda, and S. Nagata. 1993. Lethal effect of the anti-Fas antibody in mice. Nature (London) 364:806-809.
38. Rieux-Laucat, F., F. Le Deist, C. Hivroz, I. A. Roberts, K. M. Debatin, A. Fischer, and J. P. de Villartay. 1995 Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 268:1347-1349.
39. Russell, J. H., B. Rush, C. Weaver, and R. Wang. 1993. Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc. Natl. Acad. Sci. USA 90:4409-4413.
40. Sato, T., S. Irie, S. Kitada, and J. C. Reed. 1995. FAP-1: a protein tyrosine phosphatase that associates with Fas. Science 268:411-415.
41. Schwartz, L. M., S. W. Smith, M. E. Jones, and B. A. Osborne. 1993. Do all programmed cell deaths occur via apoptosis? Proc. Natl. Acad. Sci. USA 90:980-984.
42. Singer, G. G., and A. K. Abbas. 1994. The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1:365-371.
43. Smith, C. A., T. Farrah, and R. G. Goodwin. 1994. The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell 76:99-962.
44. Smith, D. B., and K. S. Johnson. 1988. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67:31-40.
45. Stanger, B. Z., P. Leder, T.-H. Lee, E. Kim, and B. Seed. 1995. RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell 81:513-523.
46. Takahashi, T., M. Tanaka, C. Brannan, N. A Jenkins, N. G. Copeland, T. Suda, and S. Nagata. 1994. Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand. Cell 76:969-976.
47. Tartaglia, L. A., T. M. Ayres, G. H. W. Wong, and D. V. Goeddel. 1993. A novel domain within the 55 kd TNF receptor signals cell death. Cell 74:845-853.
48. Tepper, C. G., S. Jayadev, B. Liu, A. Bielawska, R. Wolff, S. Yonehara, Y. Hannun, and M. Seldin. 1995. Role fore ceramide as an endogenous mediator of Fas-induced cytoloxicity. Froc. Natl. Acad. Sci. USA 92:8443-8447.
49. Tewari, M., D. R. Beidler, and V. M. Dixit. 1995. CrmA-inhibitable cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein during Fas- and tumor necrosis factor-induced apoptosis. J. Biol. Chem. 270:18738-18741.
50. Tewari, M., and V. M. Dixit. 1995. Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product. J. Biol. Chem. 270:3255-3260.
51. Thompson, C. B. 1995. Apoptosis in the pathogenesis and treatment of disease. Science 367:1456-1462.
52. Vaux, D. L., G. Haecker, and A. Strasser. 1994. An evolutionary perspective on apoptosis. Cell 76:777-779.
53. Watanabe, F. R., C. I. Brannan, N. G. Copeland, N. A. Jenkins, and S. Nagata. 1992. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature (London) 356:314-317.
54. Wyllie, A. H. 1995. The genetic regulation of apoptosis. Curr. Opin. Genet. Dev. 5:97-104.
55. Zhang, J. Unpublished data.