-
3
-
-
0036733355
-
The therapeutic potential of poly(ADP-ribose) polymerase inhibitors
-
Virag L, Szabó C: The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev, 2002; 54: 375-429
-
(2002)
Pharmacol Rev
, vol.54
, pp. 375-429
-
-
Virag, L.1
Szabó, C.2
-
4
-
-
0028294246
-
Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity
-
Zhang J, Dawson VL, Dawson TM, Snyder SH: Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science, 1994; 263: 687-89
-
(1994)
Science
, vol.263
, pp. 687-689
-
-
Zhang, J.1
Dawson, V.L.2
Dawson, T.M.3
Snyder, S.H.4
-
5
-
-
0030000690
-
DNA strand breakage, activation of poly-ADP ribosyl synthetase, and cellular energy depletion are involved in the cytotoxicity in macrophages and smooth muscle cells exposed to peroxynitrite
-
Szabó C, Zingarelli B, O'Connor M, Salzman AL: DNA strand breakage, activation of poly-ADP ribosyl synthetase, and cellular energy depletion are involved in the cytotoxicity in macrophages and smooth muscle cells exposed to peroxynitrite. Proc Natl Acad Sci USA, 1996; 93: 1753-58
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1753-1758
-
-
Szabó, C.1
Zingarelli, B.2
O'Connor, M.3
Salzman, A.L.4
-
6
-
-
0031822063
-
Peroxynitrite-induced thymocyte apoptosis: The role of caspases and poly (ADP-ribose) synthetase (PARS) activation
-
Virág L, Scott GS, Marmer D et al: Peroxynitrite-induced thymocyte apoptosis: the role of caspases and poly (ADP-ribose) synthetase (PARS) activation. Immunology, 1998; 94: 345-55
-
(1998)
Immunology
, vol.94
, pp. 345-355
-
-
Virág, L.1
Scott, G.S.2
Marmer, D.3
-
7
-
-
0033598713
-
Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion
-
Ha HC, Snyder SH: Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion. Proc Natl Acad Sci USA, 1999; 96: 13978-82
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13978-13982
-
-
Ha, H.C.1
Snyder, S.H.2
-
8
-
-
0030842946
-
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia
-
Eliasson MJ, Sampei K, Mandir AS et al: Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nat Med, 1997; 3: 1089-95
-
(1997)
Nat Med
, vol.3
, pp. 1089-1095
-
-
Eliasson, M.J.1
Sampei, K.2
Mandir, A.S.3
-
9
-
-
0032514225
-
Genetic disruption of poly (ADP ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia-reperfusion injury
-
Zingarelli B, Salzman AL, Szabó C: Genetic disruption of poly (ADP ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia-reperfusion injury. Circ Res, 1998; 83: 85-94
-
(1998)
Circ Res
, vol.83
, pp. 85-94
-
-
Zingarelli, B.1
Salzman, A.L.2
Szabó, C.3
-
10
-
-
0032127666
-
Role of poly (ADP-ribose) synthetase activation in inflammation and reperfusion injury
-
Szabó C, Dawson VL: Role of poly (ADP-ribose) synthetase activation in inflammation and reperfusion injury. Trends Pharmacol Sci, 1998; 19: 287-98
-
(1998)
Trends Pharmacol Sci
, vol.19
, pp. 287-298
-
-
Szabó, C.1
Dawson, V.L.2
-
11
-
-
0030870278
-
Inhibition of poly (ADP-ribose) synthetase exerts anti-inflammatory effects and inhibits neutrophil recruitment
-
Szabó C, Lim LH, Cuzzocrea S et al: Inhibition of poly (ADP-ribose) synthetase exerts anti-inflammatory effects and inhibits neutrophil recruitment. J Exp Med, 1997; 186: 1041-49
-
(1997)
J Exp Med
, vol.186
, pp. 1041-1049
-
-
Szabó, C.1
Lim, L.H.2
Cuzzocrea, S.3
-
12
-
-
0032545762
-
Protective effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthase in a carrageenan-induced model of local inflammation
-
Cuzzocrea S, Zingarelli B, Gilad E et al: Protective effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthase in a carrageenan-induced model of local inflammation. Eur J Pharm, 1998; 342: 67-76
-
(1998)
Eur J Pharm
, vol.342
, pp. 67-76
-
-
Cuzzocrea, S.1
Zingarelli, B.2
Gilad, E.3
-
13
-
-
0032926291
-
Blockade of Poly(ADP-ribose) synthetase inhibits neutrophil recruitment, oxidant generation, and mucosal injury in murine colitis
-
Zingarelli B, Szabó C, Salzman AL: Blockade of Poly(ADP-ribose) synthetase inhibits neutrophil recruitment, oxidant generation, and mucosal injury in murine colitis. Gastroenterology, 1999; 116: 335-45
-
(1999)
Gastroenterology
, vol.116
, pp. 335-345
-
-
Zingarelli, B.1
Szabó, C.2
Salzman, A.L.3
-
14
-
-
0032584164
-
Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly (ADP-ribose) synthetase
-
Szabó C, Virág L, Cuzzocrea S et al: Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly (ADP-ribose) synthetase. Proc Natl Acad Sci USA, 1998; 95: 3867-72
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3867-3872
-
-
Szabó, C.1
Virág, L.2
Cuzzocrea, S.3
-
15
-
-
0344721492
-
Resistance to endotoxic shock as a consequence of defective NF-kappa B activation in poly (ADP-ribose) polymerase-1 deficient mice
-
Oliver FJ, Menissier-de Murcia J, Nacci C et al: Resistance to endotoxic shock as a consequence of defective NF-kappa B activation in poly (ADP-ribose) polymerase-1 deficient mice. EMBO J, 1999; 18: 4446-54
-
(1999)
EMBO J
, vol.18
, pp. 4446-4454
-
-
Oliver, F.J.1
Menissier-De Murcia, J.2
Nacci, C.3
-
16
-
-
0036391974
-
Poly(ADP-ribose) polymerase is a regulator of chemokine production: Relevance for the pathogenesis of shock and inflammation
-
Hasko G, Mabley JG, Nemeth ZH et al: Poly(ADP-ribose) polymerase is a regulator of chemokine production: relevance for the pathogenesis of shock and inflammation. Mol Med, 2002; 8: 283-89
-
(2002)
Mol Med
, vol.8
, pp. 283-289
-
-
Hasko, G.1
Mabley, J.G.2
Nemeth, Z.H.3
-
17
-
-
0035256994
-
Chemokines: Immunology's high impact factors
-
Mackay CR: Chemokines: immunology's high impact factors. Nat Immunol, 2001; 2: 95-101
-
(2001)
Nat Immunol
, vol.2
, pp. 95-101
-
-
Mackay, C.R.1
-
18
-
-
0033557385
-
Interleukin-8 receptor modulates IgE production and B-cell expansion and trafficking in allergen-induced pulmonary inflammation
-
De Sanctis GT, MacLean JA, Qin S et al: Interleukin-8 receptor modulates IgE production and B-cell expansion and trafficking in allergen-induced pulmonary inflammation. J Clin Invest, 1999; 103: 507-15
-
(1999)
J Clin Invest
, vol.103
, pp. 507-515
-
-
De Sanctis, G.T.1
MacLean, J.A.2
Qin, S.3
-
19
-
-
0035205574
-
Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase
-
Mabley JG, Jagtap P, Perretti M et al: Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase. Inflamm Res, 2001; 50: 561-69
-
(2001)
Inflamm Res
, vol.50
, pp. 561-569
-
-
Mabley, J.G.1
Jagtap, P.2
Perretti, M.3
-
20
-
-
0035136240
-
Diabetic endothelial dysfunction: The role of poly(ADP-ribose) polymerase activation
-
Soriano FG, Virag L, Jagtap P et al: Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat Med 2001; 7: 108-13
-
(2001)
Nat Med
, vol.7
, pp. 108-113
-
-
Soriano, F.G.1
Virag, L.2
Jagtap, P.3
-
21
-
-
17144447467
-
Novel phenanthridinone inhibitors of poly(adenosine 5'-diphosphate-ribose) synthetase: Potent cytoprotective and antishock agents
-
Jagtap P, Soriano FG, Virag L et al: Novel phenanthridinone inhibitors of poly(adenosine 5'-diphosphate-ribose) synthetase: potent cytoprotective and antishock agents. Crit Care Med, 2002; 30: 1071-82
-
(2002)
Crit Care Med
, vol.30
, pp. 1071-1082
-
-
Jagtap, P.1
Soriano, F.G.2
Virag, L.3
-
22
-
-
0036135718
-
Eosinophils, eosinophilic cytokines (interleukin-5), and antieosinophilic therapy in asthma
-
Menzies-Gow A, Robinson DS: Eosinophils, eosinophilic cytokines (interleukin-5), and antieosinophilic therapy in asthma. Curr Opin Pulm Med, 2002; 8: 33-38
-
(2002)
Curr Opin Pulm Med
, vol.8
, pp. 33-38
-
-
Menzies-Gow, A.1
Robinson, D.S.2
-
23
-
-
0034581229
-
Chemokines and their role in airway hyper-reactivity
-
Blease K, Lukacs NW, Hogaboam CM, Kunkel SL: Chemokines and their role in airway hyper-reactivity. Respir Res, 2000; 1: 54-61
-
(2000)
Respir Res
, vol.1
, pp. 54-61
-
-
Blease, K.1
Lukacs, N.W.2
Hogaboam, C.M.3
Kunkel, S.L.4
-
24
-
-
0037326942
-
Chemokines in asthma: Cooperative interaction between chemokines and IL-13
-
Rosenwasser LJ, Zimmermann N, Hershey GK et al: Chemokines in asthma: Cooperative interaction between chemokines and IL-13. J Allergy Clin Immunol, 2003; 111: 227-42
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 227-242
-
-
Rosenwasser, L.J.1
Zimmermann, N.2
Hershey, G.K.3
-
25
-
-
0034791318
-
Regulation and distribution of MAdCAM-1 in endothelial cells in vitro
-
Oshima T, Pavlick KP, Laroux FS et al: Regulation and distribution of MAdCAM-1 in endothelial cells in vitro. Am J Physiol Cell Physiol, 2001; 281: C1096-105
-
(2001)
Am J Physiol Cell Physiol
, vol.281
-
-
Oshima, T.1
Pavlick, K.P.2
Laroux, F.S.3
-
26
-
-
0037446371
-
Decrease of the inflammatory response and induction of the Akt/protein kinase B pathway by poly-(ADP-ribose) polymerase 1 inhibitor in endotoxin-induced septic shock
-
Veres B, Gallyas F Jr, Varbiro G et al: Decrease of the inflammatory response and induction of the Akt/protein kinase B pathway by poly-(ADP-ribose) polymerase 1 inhibitor in endotoxin-induced septic shock. Biochem Pharmacol, 2003; 65: 1373-82
-
(2003)
Biochem Pharmacol
, vol.65
, pp. 1373-1382
-
-
Veres, B.1
Gallyas Jr., F.2
Varbiro, G.3
-
27
-
-
0034938095
-
Peroxynitrite production, DNA breakage, and poly(ADP-ribose) polymerase activation in a mouse model of oxazolone-induced contact hypersensitivity
-
Szabó E, Virag L, Bakondi E et al: Peroxynitrite production, DNA breakage, and poly(ADP-ribose) polymerase activation in a mouse model of oxazolone-induced contact hypersensitivity. J Invest Dermatol 2001; 117: 74-80
-
(2001)
J Invest Dermatol
, vol.117
, pp. 74-80
-
-
Szabó, E.1
Virag, L.2
Bakondi, E.3
-
28
-
-
0032863224
-
A role of poly (ADP-ribose) polymerase in NF-kappa B transcriptional activation
-
Hassa PO, Hottiger MO: A role of poly (ADP-ribose) polymerase in NF-kappa B transcriptional activation. Biol Chem, 1999; 380: 953-58
-
(1999)
Biol Chem
, vol.380
, pp. 953-958
-
-
Hassa, P.O.1
Hottiger, M.O.2
-
29
-
-
0035824647
-
The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function
-
Hassa PO, Covic M, Hasan S et al: The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function. J Biol Chem, 2001; 276: 45588-97
-
(2001)
J Biol Chem
, vol.276
, pp. 45588-45597
-
-
Hassa, P.O.1
Covic, M.2
Hasan, S.3
-
30
-
-
0035861675
-
The sequence-specific DNA binding of NF-kappa B is reversibly regulated by the automodification reaction of poly (ADP-ribose) polymerase 1
-
Chang WJ, Alvarez-Gonzalez R: The sequence-specific DNA binding of NF-kappa B is reversibly regulated by the automodification reaction of poly (ADP-ribose) polymerase 1. J Biol Chem, 2001; 276: 47664-70
-
(2001)
J Biol Chem
, vol.276
, pp. 47664-47670
-
-
Chang, W.J.1
Alvarez-Gonzalez, R.2
-
31
-
-
0037022627
-
Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia
-
Ha HC, Hester LD, Snyder SH: Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia. Proc Natl Acad Sci USA, 2002; 99: 3270-75
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 3270-3275
-
-
Ha, H.C.1
Hester, L.D.2
Snyder, S.H.3
-
32
-
-
0037239590
-
Poly(ADP-Ribose) Polymerase inhibitors
-
Southan GJ, Szabo C: Poly(ADP-Ribose) Polymerase inhibitors. Curr Med Chem, 2003; 10: 321-40
-
(2003)
Curr Med Chem
, vol.10
, pp. 321-340
-
-
Southan, G.J.1
Szabo, C.2
-
33
-
-
0037370764
-
Gene knockout or pharmacological inhibition of poly(ADP-ribose) polymerase-1 prevents lung inflammation in a murine model of asthma
-
Boulares AH, Zoltoski AJ, Sherif ZA et al: Gene knockout or pharmacological inhibition of poly(ADP-ribose) polymerase-1 prevents lung inflammation in a murine model of asthma. Am J Respir Cell Mol Biol, 2003; 28: 322-29
-
(2003)
Am J Respir Cell Mol Biol
, vol.28
, pp. 322-329
-
-
Boulares, A.H.1
Zoltoski, A.J.2
Sherif, Z.A.3
|