Comparison of the pharmacological properties of rat Nav 1.8 with rat Nav 1.2a and human Nav 1.5 voltage-gated sodium channel subtypes using a membrane potential sensitive dye and FLIPRR

Receptors and Channels

Volumn 10, Issue 1, 2004, Pages 11-23

  Vickery, R G ^a   Amagasu, S M ^a   Chang, R ^a   Mai, N ^a   Kaufman, E ^a   Martin, J ^a   Hembrador, J ^a   O'Keefe, M D ^a   Gee, C ^a   Marquess, D ^a   Smith, J A M ^a  

^a THERAVANCE INC   (United States)

Author keywords

FLIPRR; Membrane potential; Neuropathic pain; Sodium; Sodium channel; TTX resistant; TTX sensitive; Voltage clamp

Indexed keywords

ALLETHRIN; AMLODIPINE; BUPIVACAINE; CALCIUM; CIPERMETHRIN; DELTAMETHRIN; DYE; FELBAMATE; FENVALERATE; FLUNARIZINE; FLUORESCENT DYE; FLUSPIRILENE; ION CHANNEL; LIDOCAINE; MEXILETINE; MIBEFRADIL; NICARDIPINE; NIFEDIPINE; NITRENDIPINE; OMEGA CONOTOXIN MVIIC; PERMETHRIN; PIMOZIDE; PYRETHROID; RILUZOLE; RUFINAMIDE; SODIUM; TETRODOTOXIN; UNINDEXED DRUG; VALERIC ACID DERIVATIVE; VERATRIDINE; VOLTAGE GATED SODIUM CHANNEL; ZONISAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; CELL MEMBRANE DEPOLARIZATION; CELL TYPE; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG POTENTIATION; EVOKED RESPONSE; FLUORESCENCE ANALYSIS; INTERMETHOD COMPARISON; MEMBRANE POLARIZATION AND DEPOLARIZATION; NERVE CELL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RAT; REVIEW; SENSITIVITY ANALYSIS; VOLTAGE CLAMP;

ANIMALS; FLUORESCENT DYES; HUMANS; MUSCLE PROTEINS; NERVE TISSUE PROTEINS; PATCH-CLAMP TECHNIQUES; RATS; SODIUM; SODIUM CHANNELS; TIME FACTORS;

EID: 12144288319     PISSN: 10606823     EISSN: None     Source Type: Journal    
DOI: 10.1080/10606820490270410     Document Type: Review

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