Sodium channels in primary sensory neurons: Relationship to pain states

Novartis Foundation Symposium

Volumn 241, Issue , 2002, Pages 159-172

  Wood, John N ^a   Akopian, Armen N ^a   Baker, Mark ^a   Ding, Yanning ^a   Geoghegan, Fleur ^a   Nassar, Mohammed ^a   Malik Hall, Misbah ^a   Okuse, Kenji ^a   Poon, Louisa ^a   Ravenall, Samantha ^a   Sukumaran, Madhu ^a   Souslova, Veronika ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

TETRODOTOXIN;

ANIMAL; CHROMOSOME MAP; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HUMAN; PAIN; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW; SENSORY NERVE CELL; SODIUM CHANNEL; SPINAL GANGLION;

ANIMAL; CHROMOSOME MAPPING; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; HUMAN; NEURONS, AFFERENT; PAIN; SODIUM CHANNELS; SUPPORT, NON-U.S. GOV'T; TETRODOTOXIN;

EID: 0040075858     PISSN: None     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article

References (43)

1. Akopian AN, Souslova V, England S et al 1999a The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways. Nat Neurosci 2:541-548
2. Akopian AN, Okuse K, Souslova V, England S, Ogata N Wood JN 1999b Trans-splicing of a voltage-gated sodium channel is regulated by Nerve Growth Factor. FEBS Lett 445:177-182
3. Bevan S 2002 Modulation of sodium channels in primary afferent neurons. In: Sodium Channels and neuronal hyperexcitability. Wiley, Chichester (Novartis Found Symp 241) p 144-158
4. Baker MD, Wood JN 2001 Involvement of Na channels in pain pathways. Trends in Pharmacology 22:27-31
5. Black JA, Cummins TR, Plumpton C et al 1999 Upregulation of a silent sodium channel after peripheral, but not central, nerve injury in DRG neurons. J Neurophysiol 82:2776-2785
6. Brock JA, McLachlan EM, Belmonte C 1998 Tetrodotoxin-resistant impulses in single nociceptor nerve terminals in guinea-pig cornea. J Physiol 512:211-217
7. Boucher TJ, Okuse K, Bennett DL, Munson JB, Wood JN, McMahon SB 2000 Potent Analgesic Effects of GDNF in Neuropathic Pain States. Science 290:124-127
8. Catterall WA 2000 From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. Neuron 26:13-25
9. Caffrey JM, Eng DL, Black JA, Waxman SG, Kocsis JD 1992 Three types of sodium channels in adult rat dorsal root ganglion neurons. Brain Res 592:283-297
10. Clare JF, Tate SN, Nobbs M, Romanos MA 2000 Voltage-gated sodium channels as therapeutic targets. Drug Discovery Today 5:506-520
11. Cummins TR, Dib-Hajj SD, Black JA, Akopian AN, Wood JN, Waxman SG 1999 A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons. J Neurosci 19:RC43
12. Dib-Hajj SD, Fjell J, Cummins TR et al 1999 Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain. Pain 83:591-600
13. Elliott AA, Elliott JR 1993 Characterization of TTX-sensitive and TTX-resistant sodium currents in small cells from adult rat dorsal root ganglia. J Physiol 463:39-56
14. England S, Bevan S, Docherty RJ 1996 PGE2 modulates the tetrodotoxin-resistant sodium current in neonatal rat DRG neurones via the cAMP-protein kinase A cascade. J Physiol 495:429-440
15. Fitzgerald EM, Okuse K, Wood JN, Dolphin AC, Moss SJ 1999 cAMP-dependent phosphorylation of the tetrodotoxin-resistant voltage-dependent sodium channel SNS. J Physiol 516:433-446
16. Fjell J, Cummins TR, Davis BM et al 1999 Sodium channel expression in NGF-overexpressing transgenic mice. J Neurosci Res 57:39-47
17. Gold MS, Reichling DB, Shuster MJ, Levine JD 1996 Hyperalgesic agents increase a tetrodotoxin-resistant Na current in nociceptors. Proc Nat Acad Sci USA 93:1108-1112
18. Gold MS 1999 Tetrodotoxin-resistant Na + currents and inflammatory hyperalgesia. Proc Natl Acad Sci USA 96:7645-7649
19. Grosskreutz J, Quasthoff S, Kühn M, Grafe P 1996 Capsaicin blocks tetrodotoxin-resistant sodium potentials and calcium potentials in unmyelinated C fibres of biopsied human sural nerve in vitro. Neurosci Lett 208:49-52
20. Hartshorne RP, Messner DJ, Coppersmith JC, Catterall WA 1982 The saxitoxin receptor of the sodium channel from rat brain. Evidence for two nonidentical beta subunits. J Biol Chem 257:13888-13891
21. Isom LL 2000 Cellular and molecular biology of sodium channel beta-subunits: therapeutic implications for pain? Am J Physiol Gastrointest Liver Physiol 278:G349-G353
22. Isom 2002 β subunits: players in neuronal hyperexcitability? In: Sodium channels and neuronal hyperexcitability. Wiley, Chichester (Novartis Found Symp 241) p 124-143
23. Kazen-Gillespie KA, Ragsdale DS, D'Andrea MR, Mattei LN, Rogers KE, Isom LL 2000 Cloning, localization, and functional expression of sodium channel beta1A subunits. J Biol Chem 275:1079-1088
24. Khasar SG, Gold MS, Levine JD 1998 A tetrodotoxin-resistant sodium current mediates inflammatory pain in the rat. Neurosci Lett 256:17-20
25. Kral MG, Xiong Z, Study RE 1999 Alteration of Na+ currents in dorsal root ganglion neurons from rats with a painful neuropathy. Pain 81:15-24
26. Le Y, Sauer B 2000 Conditional gene knockout using ere recombinase. Methods Mol Biol 136:477-485
27. Lewin GR, Ritter AM, Mendell LM 1993 Nerve growth factor-induced hyperalgesia in the neonatal and adult rat. J Neurosci 13:2136-1248
28. Lyu YS, Park SK, Chung K, Chung JM 2000 Low dose of tetrodotoxin reduces neuropathic pain behaviors in an animal model. Brain Res 871:98-103
29. Malhotra JD, Kazen-Gillespie K, Hortsch M, Isom LL 2000 Sodium channel beta subunits mediate homophilic cell adhesion and recruit ankyrin to points of cell-cell contact. J Biol Chem 275:11383-11388
30. Marshall KR, Lachmann RH, Efstathiou S, Rinaldi A, Preston CM 2000 Long-term transgene expression in mice infected with a herpes simplex virus type 1 mutant severely impaired for immediate-early gene expression. J Virol 74:956-964
31. Matsuda Y, Yoshida S, Yonezawa T 1978 Tetrodotoxin sensitivity and Ca component of action potentials of mouse dorsal root ganglion cells cultured in vitro. Brain Res 154:69-82
32. Morgan K, Stevens EB, Shah B et al 2000 AP beta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics. Proc Natl Acad Sci USA 97:2308-2313
33. Ogata N, Tatebayashi H 1992 Ontogenic development of the TTX-sensitive and TTX-insensitive Na channels in neurons of the rat dorsal root ganglia. Brain Res Dev Brain Res 65:93-100
34. Planells-Cases R, Caprini M, Zhang J et al 2000 Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice. Biophys J 78:2878-2891
35. Ratcliffe CF, Qu Y, McCormick KA et al 2000 A sodium channel signaling complex: modulation by associated receptor protein tyrosine phosphatase beta. Nat Neurosci 3:437-444
36. Rinaldi A, Marshall KR, Preston CM 1999 A non-cytotoxic herpes simplex virus vector which expresses Cre recombinase directs efficient site specific recombination. Virus Res 65:11-20
37. Roy ML, Narahashi T 1992 Differential properties of TTX-sensitive and TTX-resistant sodium currents in rat dorsal root ganglion neurons. J Neurosci 12:2104-2111
38. Rush AM, Brau ME, Elliott AA, Elliott JR 1998 Electrophysiological properties of sodium current subtypes in small cells from adult rat dorsal root ganglia. J Physiol 511:771-789
39. Strassman AM, Raymond SA 1999 Electrophysiological evidence for tetrodotoxin-resistant sodium channels in slowly conducting dural sensory fibers. J Neurophysiol 81:413-424
40. Watanabe E, Fujikawa A, Matsunaga H et al 2000 Nav2/NaG channel is involved in control of salt-intake behavior in the CNS. J Neurosci 20:7743-7751
41. Waxman SG, Kocsis JD, Black JA 1994 Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is re-expressed following axotomy. J Neurophysiol 72:466-470
42. Waxman SG, Dib-Hajj S, Cummins TR, Black JA 1999 Sodium channels and pain. Proc Natl Acad Sci USA 96:7635-7639
43. Zur KB, Oh Y, Waxman SG, Black JA 1995 Differential up-regulation of sodium channel alpha-and beta 1-subunit mRNAs in cultured embryonic DRG neurons following exposure to NGF. Brain Res Mol Brain Res 30:97-105