An Abundance of Escherichia coli Is Harbored by the Mucosa-Associated Bacterial Flora of Interleukin-2-Deficient Mice

Infection and Immunity

Volumn 72, Issue 4, 2004, Pages 1983-1990

  Schuppler, M ^a,d   Lotzsch K ^a,c   Waidmann, M ^b,c   Autenrieth, I B ^b,c  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; BACTERIAL RNA; DNA 16S; INTERLEUKIN 2; RIBOSOME RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL FLORA; COLITIS; COLON MUCOSA; CONTROLLED STUDY; DNA DETERMINATION; DNA LIBRARY; DNA SEQUENCE; ENTERITIS; ENTEROBACTERIACEAE; ESCHERICHIA COLI; FLUORESCENCE IN SITU HYBRIDIZATION; INTESTINE FLORA; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TISSUE SLICE; WILD TYPE;

ANIMALS; COLITIS, ULCERATIVE; COLON; DISEASE MODELS, ANIMAL; DNA, RIBOSOMAL; ENTEROBACTERIACEAE; ESCHERICHIA COLI; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTERLEUKIN-2; INTESTINAL MUCOSA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, DNA;

EID: 12144285993     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.72.4.1983-1990.2004     Document Type: Article

References (43)

1. Amann, R., W. Ludwig, and K. H. Schleifer. 1992. Identification and in situ detection of individual bacterial cells. FEMS Microbiol. Lett. 100:45-50.
2. Amann, R. I., L. Krumholz, and D. A. Stahl. 1990. Fluorescent-oligonucleotide probing of whole cells for determinative, phylogenetic, and environmental studies in microbiology. J. Bacteriol. 172:762-770.
3. Amann, R. I., W. Ludwig, and K. H. Schleifer. 1995. Phylogenetic identification and in situ detection of individual microbial cells without cultivation. Microbiol. Rev. 59:143-169.
4. Autenrieth, I. B., N. Bucheler, E. Bohn, G. Heinze, and I. Horak. 1997. Cytokine mRNA expression in intestinal tissue of interleukin-2 deficient mice with bowel inflammation. Gut 41:793-800.
5. Berg, R. D. 1996. The indigenous gastrointestinal microflora. Trends Microbiol. 4:430-435.
6. Blumberg, R. S., L. J. Saubermann, and W. Strober. 1999. Animal models of mucosal inflammation and their relation to human inflammatory bowel disease. Curr. Opin. Immunol. 11:648-656.
7. Boudeau, J., A. L. Glasser, E. Masseret, B. Joly, and A. Darfeuille-Michaud. 1999. Invasive ability of an Escherichia coli strain isolated from the ileal mucosa of a patient with Crohn's disease. Infect. Immun. 67:4499-4509.
8. Cohavy, O., D. Bruckner, L. K. Gordon, R. Misra, B. Wei, M. E. Eggena, S. R. Targan, and J. Braun. 2000. Colonic bacteria express an ulcerative colitis pANCA-related protein epitope. Infect. Immun. 68:1542-1548.
9. Darfeuille-Michaud, A., C. Neut, N. Barnich, E. Lederman, P. Di Martino, P. Desreumaux, L. Gambiez, B. Joly, A. Cortot, and J. F. Colombel. 1998. Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease. Gastroenterology 115:1405-1413.
10. Deplancke, B., K. R. Hristova, H. A. Oakley, V. J. McCracken, R. Aminov, R. I. Mackie, and H. R. Gaskins. 2000. Molecular ecological analysis of the succession and diversity of sulfate-reducing bacteria in the mouse gastrointestinal tract. Appl. Environ. Microbiol. 66:2166-2174.
11. Dewhirst, F. E., C. C. Chien, B. J. Paster, R. L. Ericson, R. P. Orcutt, D. B. Schauer, and J. G. Fox. 1999. Phylogeny of the defined murine microbiota: altered Schaedler flora. Appl. Environ. Microbiol. 65:3287-3292.
12. Dianda, L., A. M. Hanby, N. A. Wright, A. Sebesteny, A. C. Hayday, and M. J. Owen. 1997. T cell receptor-alpha beta-deficient mice fail to develop colitis in the absence of a microbial environment. Am. J. Pathol. 150:91-97.
13. Fox, J. G., F. E. Dewhirst, G. J. Fraser, B. J. Paster, B. Shames, and J. C. Murphy. 1994. Intracellular Campylobacter-like organism from ferrets and hamsters with proliferative bowel disease is a Desulfovibrio sp. J. Clin. Microbiol. 32:1229-1237.
14. Franks, A. H., H. J. Harmsen, G. C. Raangs, G. J. Jansen, F. Schut, and G. W. Welling. 1998. Variations of bacterial populations in human feces measured by fluorescent in situ hybridization with group-specific 16S rRNA-targeted oligonucleotide probes. Appl. Environ. Microbiol. 64:3336-3345.
15. García-Lafuente, A., M. Antolín, F. Guarner, E. Crespo, A. Salas, P. Forcada, M. Laguarda, J. Gavaldá, J. A. Baena, J. Vilaseca, and J. R. Malagelada. 1997. Incrimination of anaerobic bacteria in the induction of experimental colitis. Am. J. Physiol. 272:G10-G15.
16. Gebhart, C. J., S. M. Barns, S. McOrist, G. F. Lin, and G. H. Lawson. 1993. Ileal symbiont intracellularis, an obligate intracellular bacterium of porcine intestines showing a relationship to Desulfovibrio species. Int. J. Syst. Bacteriol. 43:533-538.
17. Godon, J. J., E. Zumstein, P. Dabert, F. Habouzit, and R. Moletta. 1997. Molecular microbial diversity of an anaerobic digestor as determined by small-subunit rDNA sequence analysis. Appl. Environ. Microbiol. 63:2802-2813.
18. Lane, D. J. 1991. 16S/23S rRNA sequencing, p. 115-175. In E. Stackebrandt and M. Goodfellow (ed.), Nucleic acids techniques in bacterial systematics. John Wiley & Sons Ltd., Chichester, United Kingdom.
19. Liu, Y., H. J. van Kruiningen, A. B. West, R. W. Cartun, A. Cortot, and J. F. Colombel. 1995. Immunocytochemical evidence of Listeria, Escherichia coli, and Streptococcus antigens in Crohn's disease. Gastroenterology 108:1396-1404.
20. Manz, W., R. Amann, W. Ludwig, M. Wagner, and K. H. Schleifer. 1992. Phylogenetic oligodeoxynucleotide probes for the major subclasses of Proteobacteria: problems and solutions. Syst. Appl. Microbiol. 15:593-600.
21. Manz, W., R. Amann, W. Ludwig, M. Vancanneyt, and K. H. Schleifer. 1996. Application of a suite of 16S rRNA-specific oligonucleotide probes designed to investigate bacteria of the phylum cytophaga-flavobacter-bacteroides in the natural environment. Microbiology 142:1097-1106.
22. Marchesi, J. R., T. Sato, A. J. Weightman, T. A. Martin, J. C. Fry, S. J. Hiom, D. Dymock, and W. G. Wade. 1998. Design and evaluation of useful bacterium-specific PCR primers that amplify genes coding for bacterial 16S rRNA. Appl. Environ. Microbiol. 64:795-799. (Erratum, 64:2333.)
23. Onderdonk, A. B., J. A. Richardson, R. E. Hammer, and J. D. Taurog. 1998. Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease. Infect. Immun. 66:6022-6023.
24. Pitcher, M. C., E. R. Beatty, and J. H. Cummings. 2000. The contribution of sulphate reducing bacteria and 5-aminosalicylic acid to faecal sulphide in patients with ulcerative colitis. Gut 46:64-72.
25. Poulsen, L. K., F. Lan, C. S. Kristensen, P. Hobolth, S. Molin, and K. A. Krogfelt. 1994. Spatial distribution of Escherichia coli in the mouse large intestine inferred from rRNA in situ hybridization. Infect. Immun. 62:5191-5194.
26. Pryde, S. E., A. J. Richardson, C. S. Stewart, and H. J. Flint. 1999. Molecular analysis of the microbial diversity present in the colonic wall, colonic lumen, and cecal lumen of a pig. Appl. Environ. Microbiol. 65:5372-5377.
27. Rath, H. C., H. H. Herfarth, J. S. Ikeda, W. B. Grenther, T. E. J. Hamm, E. Balish, J. D. Taurog, R. E. Hammer, K. H. Wilson, and R. B. Sartor. 1996. Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human β2 microglobulin transgenic rats. J. Clin. Investig. 98:945-953.
28. Rath, H. C., K. H. Wilson, and R. B. Sartor. 1999. Differential induction of colitis and gastritis in HLA-B27 transgenic rats selectively colonized with Bacteroides vulgatus or Escherichia coli. Infect. Immun. 67:2969-2974.
29. Sadlack, B., H. Merz, H. Schorle, A. Schimpl, A. C. Feller, and I. Horak. 1993. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 75:253-261.
30. Sadlack, B., R. Kuhn, H. Schorle, K. Rajewski, W. Muller, and I. Horak. 1994. Development and proliferation of lymphocytes in mice deficient for both interleukins-2 and 4. Eur. J. Immunol. 24:281-284.
31. Salzman, N. H., H. de Jong, Y. Paterson, H. J. M. Harmsen, G. W. Welling, and N. A. Bos. 2002. Analysis of 16S rDNA libraries of mouse gastrointestinal microbiota reveals a large new taxon of mouse intestinal bacteria. Microbiology 148:3651-3660.
32. Sartor, R. B. 1995. Current concepts of the etiology and pathogenesis of ulcerative colitis and Crohn's disease. Gastroenterol. Clin. N. Am. 24:475-507.
33. Schultsz, C., M. Moussa, R. van Ketel, G. N. Tytgat, and J. Dankert. 1997. Frequency of pathogenic and enteroadherent Escherichia coli in patients with inflammatory bowel disease and controls. J. Clin. Pathol. 50:573-579.
34. Schuppler, M., F. Mertens, G. Schön, and U. B. Göbel. 1995. Molecular characterization of nocardioform actinomycetes in activated sludge by 16S rRNA analysis. Microbiology 141:513-521.
35. Schuppler, M., M. Wagner, G. Schön, and U. B. Göbel. 1998. In situ identification of nocardioform actinomycetes in activated sludge using fluorescent rRNA-targeted oligonucleotide probes. Microbiology 144:249-259.
36. Sellon, R. K., S. Tonkonogy, M. Schultz, L. A. Dieleman, W. Grenther, E. Balish, D. M. Rennick, and R. B. Sartor. 1998. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect. Immun. 66:5224-5231.
37. Shen, W., H. Steinruck, and A. Ljungh. 1995. Expression of binding of plasminogen, thrombospondin, vitronectin, and fibrinogen, and adhesive properties by Escherichia coli strains isolated from patients with colonic diseases. Gut 36:401-406.
38. Suau, A., R. Bonnet, M. Sutren, J. J. Godon, G. R. Gibson, M. D. Collins, and J. Dore. 1999. Direct analysis of genes encoding 16S rRNA from complex communities reveals many novel molecular species within the human gut. Appl. Environ. Microbiol. 65:4799-4807.
39. Tabaqchali, S., D. P. O'Donoghue, and K. A. Bettelheim. 1978. Escherichia coli antibodies in patients with inflammatory bowel disease. Gut 19:108-113.
40. Tannock, G. W. 1979. Coliforms and enterococci isolated from the intestinal tract of conventional mice. Microb. Ecol. 5:27-34.
41. von Wintzingerode, F., U. B. Göbel, and E. Stackebrandt. 1997. Determination of microbial diversity in environmental samples: pitfalls of PCR-based rRNA analysis. FEMS Microbiol. Rev. 21:213-229.
42. Waidmann, M., O. Bechtold, J. Frick, H. Lehr, S. Schubert, U. Dobrindt, J. Loeffler, E. Bohn, and I. B. Autenrieth. 2003. Bacteroides vulgatus protects against Escherichia coli-induced colitis in gnotobiotic interleukin-2-deficient mice. Gastroenterology 125:162-178.
43. Walmsley, R. S., A. Anthony, R. Sim, R. E. Pounder, and A. J. Wakefield. 1998. Absence of Escherichia coli, Listeria monocytogenes, and Klebsiella pneumoniae antigens within inflammatory bowel disease tissues. J. Clin. Pathol. 51:657-661.