Inhibitory effects of AMP 579, a novel cardioprotective adenosine A 1/A2A receptor agonist, on native IKr and cloned HERG current

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 370, Issue 6, 2004, Pages 492-499

  Saegusa, Noriko ^a   Sato, Toshiaki ^a   Ogura, Takehiko ^a   Komuro, Issei ^a   Nakaya, Haruaki ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

AMP 579; Cardioprotective; HEK 293 cells; HERG

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; 4 [7 [[1 [(3 CHLORO 2 THIENYL)METHYL]PROPYL]AMINO] 3H IMIDAZO[4,5 B]PYRIDIN 3 YL] N ETHYL 2,3 DIHYDROXYCYCLOPENTANECARBOXAMIDE; 8 (4 SULFOPHENYL)THEOPHYLLINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE A1 RECEPTOR AGONIST; ADENOSINE A2 RECEPTOR AGONIST; CALCIUM CHANNEL L TYPE; CHROMANOL 293B; POTASSIUM CHANNEL HERG;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CELL MEMBRANE POTENTIAL; CELL STRAIN HEK293; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE EXPRESSION; GUINEA PIG; HEART PROTECTION; HEART VENTRICLE; IC 50; KIDNEY; MUSCLE CELL; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; REPOLARIZATION; STATISTICAL SIGNIFICANCE; WHOLE CELL;

ACTION POTENTIALS; ANIMALS; CARDIOTONIC AGENTS; CATION TRANSPORT PROTEINS; CELL LINE; CELLS, CULTURED; CLONING, MOLECULAR; ETHER-A-GO-GO POTASSIUM CHANNELS; GUINEA PIGS; HUMANS; IMIDAZOLES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, VOLTAGE-GATED; PYRIDINES; RECEPTOR, ADENOSINE A1; RECEPTOR, ADENOSINE A2A;

EID: 12144262249     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-004-0999-1     Document Type: Article

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