Suggestion for present and future use of parenteral glutamine

Clinical Nutrition, Supplement

Volumn 1, Issue 1, 2004, Pages 37-42

  Wernerman, Jan ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Dosage of glutamine; Glutamine dipeptides; Glutathione; Parenteral glutamine; Route of administration

Indexed keywords

GLUTAMINE; GLUTATHIONE;

CLINICAL PRACTICE; DIET SUPPLEMENTATION; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG TISSUE LEVEL; HUMAN; IMMUNOCOMPETENCE; INTENSIVE CARE UNIT; METABOLIC PARAMETERS; MORTALITY; NUTRITIONAL SCIENCE; PARENTERAL NUTRITION; REVIEW; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

EID: 12144252078     PISSN: 17441161     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clnu.2004.07.008     Document Type: Review

References (34)

1. F. Novak D.K. Heyland A. Avenell J.W. Drover X. Su Glutamine supplementation in serious illness a systematic review of the evidence Crit Care Med 30 2002 2022-2029
2. D.K. Heyland R. Dhaliwal J.W. Drover L. Gramlich P. Dodek The Canadian Critical Care Clinical Practice Guidelines Committee Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients J Parenter Enteral Nutr 27 2003 355-373
3. R.D. Griffiths C. Jones T.E.A. Palmer Six-month outcome of critically ill patients given glutamine supplemented parenteral nutrition Nutrition 13 1997 295-302
4. C. Goeters A. Wenn N. Mertes et al. Parenteral L-alanyl-L-glutamine improves six month outcome in critically ill patients Crit Care Med 30 2002 2032-2037
5. H.M. Oudemans-van Straaten R.J. Bosman M. Treskes H.J. van der Spoel D.F. Zandsra Plasma glutamine depletion and patient outcome in acute ICU admissions Intens Care Med 27 2001 84-90
6. S. Albers J. Wernerman P. Stehle E. Vinnars P. Fürst Availability of amino acids supplied intravenously in healthy men as synthetic dipeptides. Pharmacokinetic evaluation of L-alanyl-L-glutamine and L -glycyl-L-tyrosine Clin Sci 75 1988 463-468
7. A. Berg E. Forsberg J. Wernerman The local vascular tolerance to an intravenous infusion of a concentrated glutamine solution in ICU patients Clin Nutr 21 2002 135-139
8. H.G. Kulkarni D.H. Nandal J. Pardeshi et al. Perpheral venous tolerance of 20% alanyl-glutamine dipeptide Clin Nutr 22 Suppl. 2 2003 115
9. A.P.J. Houdijk E.R. Rijnsburger J. Jansen et al. Glutamine enriched enteral nutrition reduces infectious morbidity in multitrauma patients a double-blind, prospective, randomized trial Lancet 352 1998 772-776
10. S. Claeyssens C. Bouteloup-Demange P. Gachon et al. Effect of enteral glutamine on leucine, phenylalanine and glutamine metabolism in hypercortisolemic subjects Am J Physiol 278 2000 E817-24
11. J.A. Krishnan P.B. Parce A. Martinez G.B. Diette R.G. Brower Caloric intake in medical ICU patients consistency of care with guidelines and relationship to clinical outcomes Chest 124 2003 297-305
12. C. Jones A. Palmer R. Griffiths Randomized clinical outcome study of critically ill patients given glutamine-supplemented enteral nutrition Nutrition 15 1999 108-115
13. J.C. Hall G. Dobb J. Hall R. de Sousa L. Brennan R. McCauley A prospective randomized trial of enteral glutamine in critical illness Intens Care Med 29 2003 1710-1716
14. D. Garrel J. Patenaude B. Nedelec et al. Decreased mortality and infectious morbidity in adult burn patients given enteral glutamine supplements a prospective, controlled, randomized clinical trial Crit Care Med 31 2003 2444-2449
15. R. Conejero A. Bonet T. Grau et al. Effect of a glutamine-enriched enteral diet on intestinal permeability and infectious morbidity at 28 days in critically ill patients with systemic inflammatory response syndrome a randomized, single-blind, prospective, multicenter study Nutrition 18 2002 716-721
16. P. Zhou Y- M. Jiang Z- H. Sun Y- R. Wang X- L. Ma E- D. Wilmore The effect of supplemental enteral glutamine on plasma levels, gut function and outcome in severe burns a randomized, double-blind, controlled clinical trial J Parenter Enteral Nutr 27 2003 241-245
17. I. Tjäder O. Rooyackers Forsberg A.M. V.R. Vesali P.J. Garlick J. Wernerman Effects of skeletal muscle of intravenous glutamine supplementation in ICU patients ICM 30 2004 266-275
18. B.A.C. van Acker K.W.E. Hulsewé A.J.M. Wagenmakers M.F. von Meyenfeldt P.B. Soeters Response of glutamine metabolism to glutamine-supplemented parenteral nutrition Am J Clin Nutr 72 2000 790-795
19. J. Karner E. Roth G. Ollenschlager P. Furst A. Simmel J. Karner Glutamine-containing dipeptides as infusion substrates in the septic state Surgery 106 1989 893-900
20. R.F. Vesali M. Klaude O.E. Rooyackers I. Tjäder H. Barle J. Wernerman Longitudinal pattern of glutamine/glutamate balance across the leg in long-stay intensive care unit patients Clin Nutr 21 2002 505-514
21. A. Berg L. Gamrin C. Martling O. Rooyackers J. Wernerman Glutamine losses due to continuous renal replacement therapy (CRRP) in ICU patients Clin Nutr 21 suppl 1 2002 85
22. L. Gamrin P. Essén K. Andersson E. Hultman E. Nilsson J. Wernerman Longitudinal changes of biochemical parameter in muscle during critical illness Metabolism 46 1997 756-762
23. J.C. Preiser J. Berre Y. Carpentier et al. Management of nutrition in European intensive care units results of a questionnaire. Working Group on Metabolism and Nutrition of the European Society of Intensive Care Medicine Intens Care Med 25 1999 95-101
24. D. Häussinger E. Roth F. Lang W. Gerok Cellular hydration state an important determinant of protein catabolism in health and disease Lancet 441 1993 1330-1332
25. P. Dechelotte G. Bleichner M. Hasselmann J. Dassonville B. Allaouchiche P. Czernichow J. Rangaraj Improved clinical outcome in ICU patients receiving alanyl-glutamine (Dipeptiven) supplemented total parenteral nutrition (TPN). A French double-blind multicenter study Clin Nut 21 Suppl. 1 2002 1
26. S.E. Khogali S.D. Pringle B.V. Weryk M.J. Rennie Is glutamine beneficial in ischemic heart disease? Nutrition 18 2002 123-126
27. Coiffier M, Dechelotte P. Parenteral glutamine in critically ill patients: Effects on complication rate and glucose homeostasis. Clin Nutr Suppl 2004; 1: This issue, doi: 10.1016/j.clnu.2004.07.005 .
28. Fürst P, Alteheld B, Stehle P. Why should a single nutrient-glutamine-improve outcome? The remarkable story of glutamine dipeptides. Clin Nutr Suppl 2004; 1: This issue, doi: 10.1016/j.clnu.2004.07.006 .
29. L. Luo J-F. Hammarqvist K. Andersson J. Wernerman Surgical trauma decreases the synthesis of glutathione in skeletal muscle Am J Physiol 275 1998 E359-E365
30. F. Hammarqvist L. Luo J-K. Andersson I.A. Cotgreave J. Wernerman Skeletal muscle glutathione is depleted in critically ill patients Crit Care Med 25 1997 78-84
31. U.B. Fläring O.E. Rooyackers J. Wernerman F. Hammarqvist Glutamine attenuates post-traumatic glutathione depletion in human muscle Clin Sci 104 2003 275-282
32. U. Fläring O. Rooyackers J. Wernerman F. Hammarqvist Longitudinal changes in muscle glutathion in ICU patients ICM 29 2003 2193-2198
33. D. Brealey M. Brand I. Hargreaves Association between mitochondrial dysfunction and severity and outcome of septic shock Lancet 360 2000 219-323
34. U. Fläring O. Rooyackers C. Hebert F. Hammarqvist J. Wernerman Longitudinal changes in whole blood glutathion in ICU patients Clin Nutr 22 Suppl. 1 2003 S48