Interplay of flexibility and stability in the control of estrogen receptor activity

Biochemistry

Volumn 44, Issue 2, 2005, Pages 790-798

  Bouter, A ^a   Le Tilly, V ^a   Sire, O ^a  

^a UNIVERSITÉ DE BRETAGNE SUD   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEXATION; DISSOCIATION; DNA; PROTEINS; STOICHIOMETRY;

EQUILIBRIUM BINDING; EQUILIBRIUM CONSTANTS; ESTROGEN RESPONSE ELEMENTS (ERE); PROTEIN FLUCTUATIONS;

GENES;

ESTROGEN RECEPTOR ALPHA; POTASSIUM CHLORIDE;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA BINDING; ESTROGEN RESPONSIVE ELEMENT; KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; STOICHIOMETRY; TRANSCRIPTION REGULATION;

ANIMALS; BASE PAIR MISMATCH; DNA-BINDING PROTEINS; ESTROGEN RECEPTOR ALPHA; FLUORESCENCE POLARIZATION; HUMANS; KINETICS; LIGANDS; MACROMOLECULAR SUBSTANCES; ONCORHYNCHUS MYKISS; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RESPONSE ELEMENTS; SALTS; THERMODYNAMICS; TRANS-ACTIVATION (GENETICS); TRYPTOPHAN;

ONCORHYNCHUS MYKISS; SALMONIDAE;

EID: 12144251362     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0483716     Document Type: Article

References (56)

1. Chen, D., Hinkley, C. S., Henry, R. W., and Huang, S. (2002) TBP dynamics in living human cells: constitutive association of TBP with mitotic chromosomes, Mol. Biol. Cell 13, 276-284.
2. McNally, J. G., Muller, W. G., Walker, D., Wolford, R., and Hager, G. L. (2000) The glucocorticoid receptor: rapid exchange with regulatory sites in living cells, Science 287, 1262-1265.
3. Misteli, T. (2001) Protein dynamics: implications for nuclear architecture and gene expression, Science 291, 843-847.
4. Stenoien, D. L., Patel, K., Mancini, M. G., Dutertre, M., Smith, C. L., O'Malley, B. W., and Mancini, M. A. (2001) FRAP reveals that mobility of estrogen receptor-alpha is ligand- and proteasome-dependent, Nat. Cell. Biol. 3, 15-23.
5. Spector, D. L. (2003) The dynamics of chromosome organization and gene regulation. Annu. Rev. Biochem. 72, 573-608.
6. Jenuwein, T., and Allis, C. D. (2001) Translating the histone code, Science 293, 1074-1080.
7. Lemon, B., Inouye, C., King, D. S., and Tjian, R. (2001) Selectivity of chromatin-remodelling cofactors for ligand-activated transcription, Nature 414, 924-928.
8. Hager, G. L., Elbi, C., and Becker, M. (2002) Protein dynamics in the nuclear compartment, Curr. Opin. Genet. Dev. 12, 137-141.
9. Phair, R. D., and Misteli, T. (2000) High mobility of proteins in the mammalian cell nucleus, Nature 404, 604-609.
10. Kimura, H., and Cook, P. R. (2001) Kinetics of core histones in living human cells: little exchange of H3 and H4 and some rapid exchange of H2B, J. Cell. Biol. 153, 1341-1353.
11. Freeman, B. C., and Yamamoto, K. R. (2002) Disassembly of transcriptional regulatory complexes by molecular chaperones, Science 296, 2232-2235.
12. Mangelsdorf, D. J., Thummel, C., Beato, M., Herrlich, P., Schutz, G., Umesono, K., Blumberg, B., Kastner, P., Mark, M., and Chambon, P. (1995) The nuclear receptor superfamily: the second decade, Cell 83, 835-839.
13. Yamashita, S. (1998) Localization and functions of steroid hormone receptors, Histol. Histopathol. 13, 255-270.
14. Ylikomi, T., Wurtz, J. M., Syvala, H., Passinen, S., Pekki, A., Haverinen, M., Blauer, M., Tuohimaa, P., and Gronemeyer, H. (1998) Reappraisal of the role of heat shock proteins as regulators of steroid receptor activity,Crit. Rev. Biochem. Mol. Biol. 33, 437-466.
15. Stenoien, D. L., Mancini, M. G., Patel, K., Allegretto, E. A., Smith, C. L., and Mancini, M. A. (2000) Subnuclear trafficking of estrogen receptor-alpha and steroid receptor coactivator-1, Mol. Endocrinol. 14, 518-534.
16. Bourguet, W., Ruff, M., Chambon, P., Gronemeyer, H., and Moras, D. (1995) Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha, Nature 375, 377-382.
17. Brzozowski, A. M., Pike, A. C., Dauter, Z., Hubbard, R. E., Bonn, T., Engstrom, O., Ohman, L., Greene, G. L., Gustafsson, J. A., and Carlquist, M. (1997) Molecular basis of agonism and antagonism in the oestrogen receptor, Nature 389, 753-758.
18. Pike, A. C., Brzozowski, A. M., Hubbard, R. E., Bonn, T., Thorsell, A. G., Engstrom, O., Ljunggren, J., Gustafsson, J. A., and Carlquist, M. (1999) Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist, EMBO J. 18, 4608-4618.
19. Guiochon-Mantel, A., Delabre, K., Lescop, P., and Milgrom, E. (1996) The Ernst Schering Poster Award. Intracellular traffic of steroid hormone receptors, J. Steroid Biochem. Mol. Biol. 56, 3-9.
20. Tzeng, D. Z., and Klinge, C. (1996) Phosphorylation of purified estradiol-liganded estrogen receptor by casein kinase II increases estrogen response element binding but does not alter ligand stability, Biochem. Biophys. Res. Commun. 223, 554-560.
21. Lu, Q., Surks, H. K., Ebling, H., Baur, W. E., Brown, D., Pallas, D. C., and Karas, R. H. (2003) Regulation of estrogen receptor alpha-mediated transcription by a direct interaction with protein phosphatase 2A, J. Biol. Chem. 278, 4639-4645.
22. Kato, S., Endoh, H., Masuhiro, Y., Kitamoto, T., Uchiyama, S., Sasaki, H., Masushige, S., Gotoh, Y., Nishida, E., and Kawashima, H. (1995) Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase, Science 270, 1491-1494.
23. Kullmann, M., Schneikert, J., Moll, J., Heck, S., Zeiner, M., Gehring, U., and Cato, A. C. (1998) RAP46 is a negative regulator of glucocorticoid receptor action and hormone-induced apoptosis, J. Biol. Chem. 273, 14620-14625.
24. Montano, M. M., Muller, V., Trobaugh, A., and Katzenellenbogen, B. S. (1995) The carboxy-terminal F domain of the human estrogen receptor: role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogen antagonists, Mol. Endocrinol. 9, 814-825.
25. Green, S., Walter, P., Kumar, V., Krust, A., Bornert, J. M., Argos, P., and Chambon, P. (1986) Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A, Nature 320, 134-139.
26. Kuiper, G. G., Enmark, E., Pelto-Huikko, M., Nilsson, S., and Gustafsson, J. A. (1996) Cloning of a novel receptor expressed in rat prostate and ovary, Proc. Natl. Acad. Sci. U.S.A. 93, 5925-5930.
27. Flouriot, G., Brand, H., Denger, S., Metivier, R., Kos, M., Reid, G., Sonntag-Buck, V., and Gannon, F. (2000) Identification of a new isoform of the human estrogen receptor-alpha (hER-alpha) that is encoded by distinct transcripts and that is able to repress hER-alpha activation function 1, EMBO J. 247, 4688-4700.
28. Moore, J. T., McKee, D. D., Slentz-Kesler, K., Moore, L. B., Jones, S. A., Horne, E. L., Su, J. L., Kliewer, S. A., Lehmann, J. M., and Willson, T. M. (1998) Cloning and characterization of human estrogen receptor beta isoforms, Biochem. Biophys. Res. Commun. 247, 75-78.
29. Klinge, C. M. (2001) Estrogen receptor interaction with estrogen response elements, Nucleic Acids Res. 29, 2905-2919.
30. Schwabe, J. W., Chapman, L., Finch, J. T., and Rhodes, D. (1993) The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements, Cell 75, 567-578.
31. Schultz, J. R., Loven, M. A., Melvin, V. M., Edwards, D. P., and Nardulli, A. M. (2002) Differential modulation of DNA conformation by estrogen receptors alpha and beta, J. Biol. Chem. 277, 8702-8707.
32. Pakdel, F., Le Gac, F., Le Goff, P., and Valotaire, Y. (1990) Full-length sequence and in vitro expression of rainbow trout estrogen receptor cDNA, Mol. Cell. Endocrinol. 71, 195-204.
33. Flouriot, G., Pakdel, F., and Valotaire, Y. (1996) Transcriptional and posttranscriptional regulation of rainbow trout estrogen receptor and vitellogenin gene expression, Mol. Cell. Endocrinol. 124, 173-183.
34. Flouriot, G., Pakdel, F., Ducouret, B., Ledrean, Y., and Valotaire, Y. (1997) Differential regulation of two genes implicated in fish reproduction: vitellogenin and estrogen receptor genes, Mol. Reprod. Dev. 48, 317-323.
35. Pakdel, F., Metivier, R., Flouriot, G., and Valotaire, Y. (2000) Two estrogen receptor (ER) isoforms with different estrogen dependencies are generated from the trout ER gene, Endocrinology 141, 571-580.
36. Petit, F. G., Valotaire, Y., and Pakdel, F. (1995) Differential functional activities of rainbow trout and human estrogen receptors expressed in the yeast Saccharomyces cerevisiae, Eur. J. Biochem. 233, 584-592.
37. Bouter, A. Buisine, N., Le Tilly, V., Mouchel, N., Wolff, J., and Sire, O. submitted for publication in Biochim. Biophys. Acta.
38. Wood, J. R., Likhite, V. S., Loven, M. A., and Nardulli, A. M. (2001) Allosteric modulation of estrogen receptor conformation by different estrogen response elements, Mol. Endocrinol. 15, 1114-1126.
39. Krieg, A. J., Krieg, S. A., Ahn, B. S., and Shapiro, D. J. (2004) Interplay between estrogen response element sequence and ligands controls in vivo binding of estrogen receptor to regulated genes, J. Biol. Chem. 279, 5025-5034.
40. Lagree, V., Pellerin, I., Hubert, J. F., Tacnet, F., Le Caherec, F., Roudier, N., Thomas, D., Gouranton, J., and Deschamps, S. (1998) A yeast recombinant aquaporin mutant that is not expressed or mistargeted in Xenopus oocyte can be functionally analyzed in reconstituted proteoliposomes, J. Biol. Chem. 273, 12422-12426.
41. Eftink, M. R., and Ghiron, C. A. (1976) Exposure of tryptophanyl residues in proteins. Quantitative determination by fluorescence quenching studies, Biochemistry 15, 672-680.
42. Eftink, M. R., and Ghiron, C. A. (1977) Exposure of tryptophanyl residues and protein dynamics, Biochemistry 16, 5546-5551.
43. Jamin, N., Tilly, V. L., Zargarian, L., Besancon-Yoshpe, J., Lirsac, P. N., Gabrielsen, O. S., and Toma, F. (1996) Preliminary investigation of the interaction between the R2R3 DNA binding domain of the oncoprotein C-Myb and DNA fragments, Int. J. Quantum Chem. 59, 333-341.
44. LeTilly, V., and Royer, C. A. (1993) Fluorescence anisotropy assays implicate protein-protein interactions in regulating trp repressor DNA binding, Biochemistry 32, 7753-7758.
45. Boyer, M., Poujol, N., Margeat, E., and Royer, C. A. (2000) Quantitative characterization of the interaction between purified human estrogen receptor alpha and DNA using fluorescence anisotropy, Nucleic Acids Res. 28, 2494-2502.
46. Szatkowski Ozers, M., Hill, J. J., Ervin, K., Wood, J. R., Nardulli, A. M., Royer, C. A., and Gorski, J. (1997) Equilibrium binding of estrogen receptor with DNA using fluorescence anisotropy, J. Biol. Chem. 272, 30405-30411.
47. Lawaczeck, R., and Wagner, K. G. (1974) Stacking specificity and polarization. Comparative synopsis of affinity data, Biopolymers 13, 2003-2314.
48. Ishida, T., Katsuta, M., Inoue, M., Yamagata, Y., and Tomita, K. (1983) The stacking interactions in 7-methylguanine-tryptophan systems, a model study for the interaction between the 'cap' structure of mRNA and its binding protein, Biochem. Biophys. Res. Commun. 115, 849-854.
49. Brun, F., Toulme, J. J., and Helene, C. (1975) Interactions of aromatic residues of proteins with nucleic acids. Fluorescence studies of the binding of oligopeptides containing tryptophan and tyrosine residues to polynucleotides, Biochemistry 14, 558-563.
50. 3H]estriol to induce maximal cooperativity of the estrogen receptor, J. Steroid Biochem. 20, 1027-1032.
51. Skafar, D. F., and Notides, A. C. (1985) Modulation of the estrogen receptor's affinity for DNA by estradiol, J. Biol. Chem. 260, 12208-12213.
52. Kosztin, D., Bishop, T. C., and Schulten, K. (1997) Binding of the estrogen receptor to DNA. The role of waters, Biophys. J. 73, 557-570.
53. Szatkowski Ozers, M., Hill, J. J., Ervin, K., Royer, C. A., and Gorski, J. (2001) The dissociation rate of estrogen receptor alpha from the consensus estrogen response element, Mol. Cell. Endocrinol. 175, 101-109.
54. Kladde, M. P., Xu, M., and Simpson, R. T. (1996) Direct study of DNA-protein interactions in repressed and active chromatin in living cells, EMBO J. 15, 6290-6300.
55. Carlsson, B., and Haggblad, J. (1995) Quantitative determination of DNA-binding parameters for the human estrogen receptor in a solid-phase, nonseparation assay, Anal. Biochem. 232, 172-179.
56. O'Lone, R., Frith, M. C., Karlsson, E. K., and Hansen, U. (2004) Genomic targets of nuclear estrogen receptors, Mol. Endocrinol. 18, 1859-1875.