5-Aza-2′-deoxycytidine reactivates the CDH1 gene without influencing methylation of the entire CpG island or histone modification in a human cancer cell line

Proceedings of the Japan Academy Series B: Physical and Biological Sciences

Volumn 80, Issue 7, 2004, Pages 342-348

  Tachibana, Ken ^a,b   Takeda, Ken ^b   Shiraishi, Masahiko ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

5 aza 2 deoxycytidine; CDH1; DNA methylation; Gene silencing; Histone acetylation; Histone methylation

Indexed keywords

EID: 11844263357     PISSN: 03862208     EISSN: None     Source Type: Journal    
DOI: 10.2183/pjab.80.342     Document Type: Article

References (38)

1. Bird, A. (2002) Genes Dev. 16, 6-21.
2. Gonzalez-Zulueta, M., Bender, C. M., Yang, A. S., Nguyen, T., Beart, R. W., Van Tornout, J. M., and Jones, P. A. (1995) Cancer Res. 55, 4531-4535.
3. Stirzaker, C., Millar, D. S., Paul, C. L., Warnecke, P. M., Harrison, J., Vincent, P. C., Frommer, M., and Clark, S. J. (1997) Cancer Res. 57, 2229-2237.
4. Herman, J. G., Umar, A., Polyak, K., Graff, J. R., Ahuja, N., Issa, J. P., Markowitz, S., Willson, J. K., Hamilton, S. R., Kinzler, K. W. et al. (1998) Proc. Natl. Acad. Sci. USA 95, 6870-6875.
5. Nakagawachi, T., Soejima, H., Urano, T., Zhao, W., Higashimoto, K., Satoh, Y., Matsukura, S., Kudo, S., Kitajima, Y., Harada, H. et al. (2003) Oncogene 22, 8835-8844.
6. Hiltunen, M. O., Alhonen, L., Koistinaho, J., Myohanen, S., Paakkonen, M., Marin, S., Kosma, V. M., and Janne, J. (1997) Int. J. Cancer 70, 644-648.
7. Lachner, M., O'Sullivan, R. J., and Jenuwein, T. (2003) J. Cell. Sci. 116, 2117-2124.
8. Jenuwein, T., and Allis, C. D. (2001) Science 293, 1074-1080.
9. Zhang, Y., and Reinberg, D. (2001) Genes Dev. 15, 2343-2360.
10. Noma, K., Allis, C. D., and Grewal, S. I. (2001) Science 293, 1150-1155.
11. Liang, G., Lin, J. C., Wei, V., Yoo, C., Cheng, J. C., Nguyen, C. T., Weisenberger, D. J., Egger, G., Takai, D., Gonzales, F. A., and Jones, P. A. (2004) Proc. Natl. Acad. Sci. USA 101, 7357-7362.
12. Knoepfler, P. S., and Eisenman, R. N. (1999) Cell 99, 447-450.
13. Bird, A. P., and Wolffe, A. P. (1999) Cell 99, 451-454.
14. Tamaru, H., and Selker, E. U. (2001) Nature 414, 277-283.
15. Tamaru, H., Zhang, X., McMillen, D., Singh, P. B., Nakayama, J., Grewal, S. I., Allis, C. D., Cheng, X., and Selker, E. U. (2003) Nat. Genet. 34, 75-79.
16. Jackson, J. P., Lindroth, A. M., Cao, X., and Jacobsen, S. E. (2002) Nature 416, 556-560.
17. Takeichi, M. (1991) Science 251, 1451-1455.
18. Hirohashi, S. (1998) Am. J. Pathol. 153, 333-339.
19. Koizume, S., Tachibana, K., Sekiya, T., Hirohashi, S., and Shiraishi, M. (2002) Nucleic Acids Res. 30, 4770-4780.
20. Yoshiura, K., Kanai, Y., Ochiai, A., Shimoyama, Y., Sugimura, T., and Hirohashi, S. (1995) Proc. Natl. Acad. Sci. USA 92, 7416-7419.
21. Graff, J. R., Herman, J. G., Lapidus, R. G., Chopra, H., Xu, R., Jarrard, D. F., Isaacs, W. B., Pitha, P. M., Davidson, N. E., and Baylin, S. B. (1995) Cancer Res. 55, 5195-5199.
22. Paulin, R., Grigg, G. W., Davey, M. W., and Piper, A. A. (1998) Nucleic Acids Res. 26, 5009-5010.
23. Higashimoto, K., Urano, T., Sugiura, K., Yatsuki, H., Joh, K., Zhao, W., Iwakawa, M., Ohashi, H., Oshimura, M., Niikawa, N. et al. (2003) Am. J. Hum. Genet. 73, 948-956.
24. Reinke, H., and Horz, W. (2003) Mol. Cell 11, 1599-1607.
25. Hennig, G., Behrens, J., Truss, M., Frisch, S., Reichmann, E., and Birchmeier, W. (1995) Oncogene 11, 475-484.
26. Juttermann, R., Li, E., and Jaenisch, R. (1994) Proc. Natl. Acad. Sci. USA 91, 11797-11801.
27. Karpf, A. R., Peterson, P. W., Rawlins, J. T., Dalley, B. K., Yang, Q., Albertsen, H., and Jones, D. A. (1999) Proc. Natl. Acad. Sci. USA 96, 14007-14012.
28. Bender, C. M., Pao, M. M., and Jones, P. A. (1998) Cancer Res. 58, 95-101.
29. Chen, C. L., Liu, S. S., Ip, S. M., Wong, L. C., Ng, T. Y., and Ngan, H. Y. (2003) Eur. J. Cancer 39, 517-523.
30. Ribeiro-Filho, L. A., Franks, J., Sasaki, M., Shiina, H., Li, L. C., Nojima, D., Arap, S., Carroll, P., Enokida, H., Nakagawa, M. et al. (2002) Mol. Carcinog. 34, 187-198.
31. Rhee, I., Jair, K. W., Yen, R. W., Lengauer, C., Herman, J. G., Kinzler, K. W., Vogelstein, B., Baylin, S. B., and Schuebel, K. E. (2000) Nature 404, 1003-1007.
32. Takebayashi, S., Nakao, M., Fujita, N., Sado, T., Tanaka, M., Taguchi, H., and Okumura, K. (2001) Biochem. Biophys. Res. Commun. 288, 921-926.
33. Nguyen, C. T., Weisenberger, D. J., Velicescu, M., Gonzales, F. A., Lin, J. C., Liang, G., and Jones, P. A. (2002) Cancer Res. 62, 6456-6461.
34. Fahrner, J. A., Eguchi, S., Herman, J. G., and Baylin, S. B. (2002) Cancer Res. 62, 7213-7218.
35. Cano, A., Perez-Moreno, M. A., Rodrigo, I., Locascio, A., Blanco, M. J., del Barrio, M. G., Portillo, F., and Nieto, M. A. (2000) Nat. Cell Biol. 2, 76-83.
36. Batlle, E., Sancho, E., Franci, C., Dominguez, D., Monfar, M., Baulida, J., and Garcia de Herreros, A. (2000) Nat. Cell Biol. 2, 84-89.
37. Roberts, C. W., and Orkin, S. H. (2004) Nat. Rev. Cancer 4, 133-142.
38. Lusser, A., and Kadonaga, J. T. (2003) Bioessays 25, 1192-1200.