-
1
-
-
0023221667
-
Cloning of human mineralocorticoid receptor complementary DNA: Structural and functional kinship with the glucocorticoid receptor
-
Arriza J.L., Weinberger C., Cerelli G., Glaser T.M., Handelin B.L., Housman D.E., Evans R.M. Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor. Science. 237:1987;268-275.
-
(1987)
Science
, vol.237
, pp. 268-275
-
-
Arriza, J.L.1
Weinberger, C.2
Cerelli, G.3
Glaser, T.M.4
Handelin, B.L.5
Housman, D.E.6
Evans, R.M.7
-
2
-
-
0031862891
-
Anti-inflammatory actions of glucocorticoids: Molecular mechanisms
-
Barnes P.J. Anti-inflammatory actions of glucocorticoids: molecular mechanisms. Clin. Sci. (Lond.). 94:1998;557-572.
-
(1998)
Clin. Sci. (Lond.)
, vol.94
, pp. 557-572
-
-
Barnes, P.J.1
-
3
-
-
0030903739
-
Dexamethasone and 11-dehydrodexamethasone as tools to investigate the isozymes of 11 beta-hydroxysteroid dehydrogenase in vitro and in vivo
-
Best R., Nelson S.M., Walker B.R. Dexamethasone and 11- dehydrodexamethasone as tools to investigate the isozymes of 11 beta-hydroxysteroid dehydrogenase in vitro and in vivo. J. Endocrinol. 153:1997;41-48.
-
(1997)
J. Endocrinol.
, vol.153
, pp. 41-48
-
-
Best, R.1
Nelson, S.M.2
Walker, B.R.3
-
4
-
-
18444405534
-
Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition
-
Bledsoe R.K., Montana V.G., Stanley T.B., Delves C.J., Apolito C.J., McKee D.D., Consler T.G., Parks D.J., Stewart E.L., Willson T.M., Lambert M.H., Moore J.T., Pearce K.H., Xu H.E. Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition. Cell. 110:2002;93-105.
-
(2002)
Cell
, vol.110
, pp. 93-105
-
-
Bledsoe, R.K.1
Montana, V.G.2
Stanley, T.B.3
Delves, C.J.4
Apolito, C.J.5
McKee, D.D.6
Consler, T.G.7
Parks, D.J.8
Stewart, E.L.9
Willson, T.M.10
Lambert, M.H.11
Moore, J.T.12
Pearce, K.H.13
Xu, H.E.14
-
5
-
-
0029899120
-
Evidence using a green fluorescent protein-glucocorticoid receptor chimera that the Ran/TC4 GTPase mediates an essential function independent of nuclear protein import
-
Carey K.L., Richards S.A., Lounsbury K.M., Macara I.G. Evidence using a green fluorescent protein-glucocorticoid receptor chimera that the Ran/TC4 GTPase mediates an essential function independent of nuclear protein import. J. Cell Biol. 133:1996;985-996.
-
(1996)
J. Cell Biol.
, vol.133
, pp. 985-996
-
-
Carey, K.L.1
Richards, S.A.2
Lounsbury, K.M.3
MacAra, I.G.4
-
6
-
-
0015861774
-
Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
-
Cheng Y., Prusoff W.H. Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem. Pharmacol. 22:1973;3099-3108.
-
(1973)
Biochem. Pharmacol.
, vol.22
, pp. 3099-3108
-
-
Cheng, Y.1
Prusoff, W.H.2
-
7
-
-
0031008086
-
Metabolism of dexamethasone in the human kidney: Nicotinamide adenine dinucleotide-dependent 11beta-reduction
-
Diederich S., Hanke B., Oelkers W., Bahr V. Metabolism of dexamethasone in the human kidney: nicotinamide adenine dinucleotide-dependent 11beta-reduction. J. Clin. Endocrinol. Metab. 82:1997;1598-1602.
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 1598-1602
-
-
Diederich, S.1
Hanke, B.2
Oelkers, W.3
Bahr, V.4
-
8
-
-
0036882139
-
11beta-hydroxysteroid dehydrogenase types 1 and 2: An important pharmacokinetic determinant for the activity of synthetic mineralo- and glucocorticoids
-
Diederich S., Eigendorff E., Burkhardt P., Quinkler M., Bumke-Vogt C., Rochel M., Seidelmann D., Esperling P., Oelkers W., Bahr V. 11beta- hydroxysteroid dehydrogenase types 1 and 2: an important pharmacokinetic determinant for the activity of synthetic mineralo- and glucocorticoids. J. Clin. Endocrinol. Metab. 87:2002;5695-5701.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 5695-5701
-
-
Diederich, S.1
Eigendorff, E.2
Burkhardt, P.3
Quinkler, M.4
Bumke-Vogt, C.5
Rochel, M.6
Seidelmann, D.7
Esperling, P.8
Oelkers, W.9
Bahr, V.10
-
9
-
-
0028175751
-
11 beta-Hydroxysteroid dehydrogenase accounts for low prednisolone/prednisone ratios in the kidney
-
Escher G., Frey F.J., Frey B.M. 11 beta-Hydroxysteroid dehydrogenase accounts for low prednisolone/prednisone ratios in the kidney. Endocrinology. 135:1994;101-106.
-
(1994)
Endocrinology
, vol.135
, pp. 101-106
-
-
Escher, G.1
Frey, F.J.2
Frey, B.M.3
-
10
-
-
0032539721
-
Subcellular localization of mineralocorticoid receptors in living cells: Effects of receptor agonists and antagonists
-
Fejes-Toth G., Pearce D., Naray-Fejes-Toth A. Subcellular localization of mineralocorticoid receptors in living cells: effects of receptor agonists and antagonists. Proc. Natl. Acad. Sci. U.S.A. 95:1998;2973-2978.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 2973-2978
-
-
Fejes-Toth, G.1
Pearce, D.2
Naray-Fejes-Toth, A.3
-
11
-
-
0029999371
-
Substrate and inhibitor specificity of the cloned human 11 beta-hydroxysteroid dehydrogenase type 2 isoform
-
Ferrari P., Smith R.E., Funder J.W., Krozowski Z.S. Substrate and inhibitor specificity of the cloned human 11 beta-hydroxysteroid dehydrogenase type 2 isoform. Am. J. Physiol. 270:1996;E900-E904.
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Ferrari, P.1
Smith, R.E.2
Funder, J.W.3
Krozowski, Z.S.4
-
13
-
-
0033406694
-
Specific hydroxylations determine selective corticosteroid recognition by human glucocorticoid and mineralocorticoid receptors
-
Hellal-Levy C., Couette B., Fagart J., Souque A., Gomez-Sanchez C., Rafestin-Oblin M. Specific hydroxylations determine selective corticosteroid recognition by human glucocorticoid and mineralocorticoid receptors. FEBS Lett. 464:1999;9-13.
-
(1999)
FEBS Lett.
, vol.464
, pp. 9-13
-
-
Hellal-Levy, C.1
Couette, B.2
Fagart, J.3
Souque, A.4
Gomez-Sanchez, C.5
Rafestin-Oblin, M.6
-
14
-
-
1842326161
-
Inhibition of 11 beta-hydroxysteroid dehydrogenase activity enhances the antiproliferative effect of glucocorticosteroids on MCF-7 and ZR-75-1 breast cancer cells
-
Hundertmark S., Buhler H., Rudolf M., Weitzel H.K., Ragosch V. Inhibition of 11 beta-hydroxysteroid dehydrogenase activity enhances the antiproliferative effect of glucocorticosteroids on MCF-7 and ZR-75-1 breast cancer cells. J. Endocrinol. 155:1997;171-180.
-
(1997)
J. Endocrinol.
, vol.155
, pp. 171-180
-
-
Hundertmark, S.1
Buhler, H.2
Rudolf, M.3
Weitzel, H.K.4
Ragosch, V.5
-
15
-
-
0038265311
-
The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism
-
Kauppi B., Jakob C., Farnegardh M., Yang J., Ahola H., Alarcon M., Calles K., Engstrom O., Harlan J., Muchmore S., Ramqvist A.K., Thorell S., Ohman L., Greer J., Gustafsson J.A., Carlstedt-Duke J., Carlquist M. The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism. J. Biol. Chem. 278:2003;22748-22754.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 22748-22754
-
-
Kauppi, B.1
Jakob, C.2
Farnegardh, M.3
Yang, J.4
Ahola, H.5
Alarcon, M.6
Calles, K.7
Engstrom, O.8
Harlan, J.9
Muchmore, S.10
Ramqvist, A.K.11
Thorell, S.12
Ohman, L.13
Greer, J.14
Gustafsson, J.A.15
Carlstedt-Duke, J.16
Carlquist, M.17
-
16
-
-
0030920285
-
Oxoreductase and dehydrogenase activities of the human and rat 11beta-hydroxysteroid dehydrogenase type 2 enzyme
-
Li K.X., Obeyesekere V.R., Krozowski Z.S., Ferrari P. Oxoreductase and dehydrogenase activities of the human and rat 11beta-hydroxysteroid dehydrogenase type 2 enzyme. Endocrinology. 138:1997;2948-2952.
-
(1997)
Endocrinology
, vol.138
, pp. 2948-2952
-
-
Li, K.X.1
Obeyesekere, V.R.2
Krozowski, Z.S.3
Ferrari, P.4
-
17
-
-
0030987413
-
Determinants of specificity of transactivation by the mineralocorticoid or glucocorticoid receptor
-
Lim-Tio S.S., Keightley M.C., Fuller P.J. Determinants of specificity of transactivation by the mineralocorticoid or glucocorticoid receptor. Endocrinology. 138:1997;2537-2543.
-
(1997)
Endocrinology
, vol.138
, pp. 2537-2543
-
-
Lim-Tio, S.S.1
Keightley, M.C.2
Fuller, P.J.3
-
18
-
-
0028026643
-
The mineralocorticoid receptor discriminates aldosterone from glucocorticoids independently of the 11 beta-hydroxysteroid dehydrogenase
-
Lombes M., Kenouch S., Souque A., Farman N., Rafestin-Oblin M.E. The mineralocorticoid receptor discriminates aldosterone from glucocorticoids independently of the 11 beta-hydroxysteroid dehydrogenase. Endocrinology. 135:1994;834-840.
-
(1994)
Endocrinology
, vol.135
, pp. 834-840
-
-
Lombes, M.1
Kenouch, S.2
Souque, A.3
Farman, N.4
Rafestin-Oblin, M.E.5
-
19
-
-
0022458855
-
Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA
-
Miesfeld R., Rusconi S., Godowski P.J., Maler B.A., Okret S., Wikstrom A.C., Gustafsson J.A., Yamamoto K.R. Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA. Cell. 46:1986;389-399.
-
(1986)
Cell
, vol.46
, pp. 389-399
-
-
Miesfeld, R.1
Rusconi, S.2
Godowski, P.J.3
Maler, B.A.4
Okret, S.5
Wikstrom, A.C.6
Gustafsson, J.A.7
Yamamoto, K.R.8
-
20
-
-
0029889312
-
11 beta-Hydroxysteroid dehydrogenase type 2 complementary deoxyribonucleic acid stably transfected into Chinese hamster ovary cells: Specific inhibition by 11 alpha-hydroxyprogesterone
-
Morita H., Zhou M., Foecking M.F., Gomez-Sanchez E.P., Cozza E.N., Gomez-Sanchez C.E. 11 beta-Hydroxysteroid dehydrogenase type 2 complementary deoxyribonucleic acid stably transfected into Chinese hamster ovary cells: specific inhibition by 11 alpha-hydroxyprogesterone. Endocrinology. 137:1996;2308-2314.
-
(1996)
Endocrinology
, vol.137
, pp. 2308-2314
-
-
Morita, H.1
Zhou, M.2
Foecking, M.F.3
Gomez-Sanchez, E.P.4
Cozza, E.N.5
Gomez-Sanchez, C.E.6
-
21
-
-
0037326184
-
Role of local 11 beta-hydroxysteroid dehydrogenase type 2 expression in determining the phenotype of adrenal adenomas
-
Mune T., Morita H., Suzuki T., Takahashi Y., Isomura Y., Tanahashi T., Daido H., Yamakita N., Deguchi T., Sasano H., White P.C., Yasuda K. Role of local 11 beta-hydroxysteroid dehydrogenase type 2 expression in determining the phenotype of adrenal adenomas. J. Clin. Endocrinol. Metab. 88:2003;864-870.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 864-870
-
-
Mune, T.1
Morita, H.2
Suzuki, T.3
Takahashi, Y.4
Isomura, Y.5
Tanahashi, T.6
Daido, H.7
Yamakita, N.8
Deguchi, T.9
Sasano, H.10
White, P.C.11
Yasuda, K.12
-
22
-
-
0036233763
-
Increased cortisol metabolites and reduced activity of 11beta-hydroxysteroid dehydrogenase in patients on hemodialysis
-
N'Gankam V., Uehlinger D., Dick B., Frey B.M., Frey F.J. Increased cortisol metabolites and reduced activity of 11beta-hydroxysteroid dehydrogenase in patients on hemodialysis. Kidney Int. 61:2002;1859-1866.
-
(2002)
Kidney Int.
, vol.61
, pp. 1859-1866
-
-
N'Gankam, V.1
Uehlinger, D.2
Dick, B.3
Frey, B.M.4
Frey, F.J.5
-
23
-
-
0035958952
-
The intracellular localization of the mineralocorticoid receptor is regulated by 11beta-hydroxysteroid dehydrogenase type 2
-
Odermatt A., Arnold P., Frey F.J. The intracellular localization of the mineralocorticoid receptor is regulated by 11beta-hydroxysteroid dehydrogenase type 2. J. Biol. Chem. 276:2001;28484-28492.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 28484-28492
-
-
Odermatt, A.1
Arnold, P.2
Frey, F.J.3
-
24
-
-
0033214482
-
The N-terminal anchor sequences of 11beta-hydroxysteroid dehydrogenases determine their orientation in the endoplasmic reticulum membrane
-
Odermatt A., Arnold P., Stauffer A., Frey B.M., Frey F.J. The N-terminal anchor sequences of 11beta-hydroxysteroid dehydrogenases determine their orientation in the endoplasmic reticulum membrane. J. Biol. Chem. 274:1999;28762-28770.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28762-28770
-
-
Odermatt, A.1
Arnold, P.2
Stauffer, A.3
Frey, B.M.4
Frey, F.J.5
-
25
-
-
84995839597
-
Impaired renal 11 beta-oxidation of 9 alpha-fluorocortisol: An explanation for its mineralocorticoid potency
-
Oelkers W., Buchen S., Diederich S., Krain J., Muhme S., Schoneshofer M. Impaired renal 11 beta-oxidation of 9 alpha-fluorocortisol: an explanation for its mineralocorticoid potency. J. Clin. Endocrinol. Metab. 78:1994;928-932.
-
(1994)
J. Clin. Endocrinol. Metab.
, vol.78
, pp. 928-932
-
-
Oelkers, W.1
Buchen, S.2
Diederich, S.3
Krain, J.4
Muhme, S.5
Schoneshofer, M.6
-
26
-
-
0037456999
-
Abnormal expression of 11 beta-hydroxysteroid dehydrogenase type 2 in human pituitary adenomas: A prereceptor determinant of pituitary cell proliferation
-
Rabbitt E.H., Ayuk J., Boelaert K., Sheppard M.C., Hewison M., Stewart P.M., Gittoes N.J. Abnormal expression of 11 beta-hydroxysteroid dehydrogenase type 2 in human pituitary adenomas: a prereceptor determinant of pituitary cell proliferation. Oncogene. 22:2003;1663-1667.
-
(2003)
Oncogene
, vol.22
, pp. 1663-1667
-
-
Rabbitt, E.H.1
Ayuk, J.2
Boelaert, K.3
Sheppard, M.C.4
Hewison, M.5
Stewart, P.M.6
Gittoes, N.J.7
-
27
-
-
0033304646
-
Structure/function of the human glucocorticoid receptor: Tyrosine 735 is important for transactivation
-
Ray D.W., Suen C.S., Brass A., Soden J., White A. Structure/function of the human glucocorticoid receptor: tyrosine 735 is important for transactivation. Mol. Endocrinol. 13:1999;1855-1863.
-
(1999)
Mol. Endocrinol.
, vol.13
, pp. 1855-1863
-
-
Ray, D.W.1
Suen, C.S.2
Brass, A.3
Soden, J.4
White, A.5
-
28
-
-
0033579510
-
Structural determinants of aldosterone binding selectivity in the mineralocorticoid receptor
-
Rogerson F.M., Dimopoulos N., Sluka P., Chu S., Curtis A.J., Fuller P.J. Structural determinants of aldosterone binding selectivity in the mineralocorticoid receptor. J. Biol. Chem. 274:1999;36305-36311.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 36305-36311
-
-
Rogerson, F.M.1
Dimopoulos, N.2
Sluka, P.3
Chu, S.4
Curtis, A.J.5
Fuller, P.J.6
-
29
-
-
0027239887
-
Effect of drugs on gene expression in mammalian cells: A highly efficient procedure to test large numbers of samples
-
Satoh K., Galli I., Ariga H. Effect of drugs on gene expression in mammalian cells: a highly efficient procedure to test large numbers of samples. Nucleic Acids Res. 21:1993;4429-4430.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 4429-4430
-
-
Satoh, K.1
Galli, I.2
Ariga, H.3
-
30
-
-
0027222717
-
Metabolism of dexamethasone: Sites and activity in mammalian tissues
-
Siebe H., Baude G., Lichtenstein I., Wang D., Buhler H., Hoyer G.A., Hierholzer K. Metabolism of dexamethasone: sites and activity in mammalian tissues. Ren. Physiol. Biochem. 16:1993;79-88.
-
(1993)
Ren. Physiol. Biochem.
, vol.16
, pp. 79-88
-
-
Siebe, H.1
Baude, G.2
Lichtenstein, I.3
Wang, D.4
Buhler, H.5
Hoyer, G.A.6
Hierholzer, K.7
-
31
-
-
0032611267
-
11 beta-Hydroxysteroid dehydrogenase
-
Stewart P.M., Krozowski Z.S. 11 beta-Hydroxysteroid dehydrogenase. Vitam. Horm. 57:1999;249-324.
-
(1999)
Vitam. Horm.
, vol.57
, pp. 249-324
-
-
Stewart, P.M.1
Krozowski, Z.S.2
-
32
-
-
0036137606
-
Multidrug resistance (MDR-1) expression in AIDS-related lymphomas
-
Tulpule A., Sherrod A., Dharmapala D., Young L.L., Espina B.M., Sanchez M.N., Gill P.S., Levine A.M. Multidrug resistance (MDR-1) expression in AIDS-related lymphomas. Leuk. Res. 26:2002;121-127.
-
(2002)
Leuk. Res.
, vol.26
, pp. 121-127
-
-
Tulpule, A.1
Sherrod, A.2
Dharmapala, D.3
Young, L.L.4
Espina, B.M.5
Sanchez, M.N.6
Gill, P.S.7
Levine, A.M.8
-
33
-
-
0031888997
-
Modulation of hormone-dependent glucocorticoid receptor function using a tetracycline-regulated expression system
-
Wei P., Ahn Y.I., Housley P.R., Alam J., Vedeckis W.V. Modulation of hormone-dependent glucocorticoid receptor function using a tetracycline- regulated expression system. J. Steroid. Biochem. Mol. Biol. 64:1998;1-12.
-
(1998)
J. Steroid. Biochem. Mol. Biol.
, vol.64
, pp. 1-12
-
-
Wei, P.1
Ahn, Y.I.2
Housley, P.R.3
Alam, J.4
Vedeckis, W.V.5
-
34
-
-
0031046241
-
11 beta-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess
-
White P.C., Mune T., Agarwal A.K. 11 beta-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess. Endocr. Rev. 18:1997;135-156.
-
(1997)
Endocr. Rev.
, vol.18
, pp. 135-156
-
-
White, P.C.1
Mune, T.2
Agarwal, A.K.3
-
35
-
-
0037085389
-
Distinct interaction of cortivazol with the ligand binding domain confers glucocorticoid receptor specificity: Cortivazol is a specific ligand for the glucocorticoid receptor
-
Yoshikawa N., Makino Y., Okamoto K., Morimoto C., Makino I., Tanaka H. Distinct interaction of cortivazol with the ligand binding domain confers glucocorticoid receptor specificity: cortivazol is a specific ligand for the glucocorticoid receptor. J. Biol. Chem. 277:2002;5529-5540.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 5529-5540
-
-
Yoshikawa, N.1
Makino, Y.2
Okamoto, K.3
Morimoto, C.4
Makino, I.5
Tanaka, H.6
-
36
-
-
0027169368
-
Modulation of multidrug resistance gene expression by dexamethasone in cultured hepatoma cells
-
Zhao J.Y., Ikeguchi M., Eckersberg T., Kuo M.T. Modulation of multidrug resistance gene expression by dexamethasone in cultured hepatoma cells. Endocrinology. 133:1993;521-528.
-
(1993)
Endocrinology
, vol.133
, pp. 521-528
-
-
Zhao, J.Y.1
Ikeguchi, M.2
Eckersberg, T.3
Kuo, M.T.4
|