메뉴 건너뛰기




Volumn 191, Issue SUPPL. 1, 2005, Pages

Truncated N-terminal mutants of SV40 large T antigen as minimal immortalizing agents for CNS cells

Author keywords

Cell cycle; Cell line; Growth arrest; Immortalization; Oncogene; Plasmid; SV40 large T antigen; T155c; T155g; T64 7b; Telomerase; Telomere

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; MUTANT PROTEIN; PEPTIDE; PEPTIDE T155C; PLASMID VECTOR; PROTEIN P53; TELOMERASE; UNCLASSIFIED DRUG; VIRUS LARGE T ANTIGEN;

EID: 11344289474     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.expneurol.2004.08.019     Document Type: Article
Times cited : (6)

References (76)
  • 2
    • 0022650002 scopus 로고
    • The T-unique coding domain is important to the transformation maintenance function of the simian virus 40 small t antigen
    • I. Bikel, H. Mamon, E.L. Brown, J. Boltax, M. Agha, and D.M. Livingston The T-unique coding domain is important to the transformation maintenance function of the simian virus 40 small t antigen Mol. Cell. Biol. 6 1986 1172 1178
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 1172-1178
    • Bikel, I.1    Mamon, H.2    Brown, E.L.3    Boltax, J.4    Agha, M.5    Livingston, D.M.6
  • 3
    • 0023667792 scopus 로고
    • SV40 small t antigen enhances the transformation activity of limiting concentrations of SV40 large T antigen
    • I. Bikel, X. Montano, M.E. Agha, M. Brown, M. McCormack, J. Boltax, and D.M. Livingston SV40 small t antigen enhances the transformation activity of limiting concentrations of SV40 large T antigen Cell 48 1987 321 330
    • (1987) Cell , vol.48 , pp. 321-330
    • Bikel, I.1    Montano, X.2    Agha, M.E.3    Brown, M.4    McCormack, M.5    Boltax, J.6    Livingston, D.M.7
  • 4
  • 5
    • 0031746554 scopus 로고    scopus 로고
    • Polyomavirus T antigens: Molecular chaperones for multiprotein complexes
    • J.L. Brodsky, and J.M. Pipas Polyomavirus T antigens: Molecular chaperones for multiprotein complexes J. Virol. 72 1998 5329 5334
    • (1998) J. Virol. , vol.72 , pp. 5329-5334
    • Brodsky, J.L.1    Pipas, J.M.2
  • 6
    • 0029162563 scopus 로고
    • Telomere elongation in immortal human cells without detectable telomerase activity
    • T.M. Bryan, A. Englezou, J. Gupta, S. Bacchetti, and R.R. Reddel Telomere elongation in immortal human cells without detectable telomerase activity EMBO J. 14 1995 4240 4248
    • (1995) EMBO J. , vol.14 , pp. 4240-4248
    • Bryan, T.M.1    Englezou, A.2    Gupta, J.3    Bacchetti, S.4    Reddel, R.R.5
  • 7
    • 0028322713 scopus 로고
    • SV40-induced immortalization of human cells
    • T.M. Bryan, and R.R. Reddel SV40-induced immortalization of human cells Crit. Rev. Oncog. 5 1994 331 357
    • (1994) Crit. Rev. Oncog. , vol.5 , pp. 331-357
    • Bryan, T.M.1    Reddel, R.R.2
  • 8
    • 0030964277 scopus 로고    scopus 로고
    • The biology of replicative senescence
    • J. Campisi The biology of replicative senescence Eur. J. Cancer 33 1997 703 709
    • (1997) Eur. J. Cancer , vol.33 , pp. 703-709
    • Campisi, J.1
  • 9
    • 0024508660 scopus 로고
    • Immortalization of neural cells via retrovirus-mediated oncogene transduction
    • C.L. Cepko Immortalization of neural cells via retrovirus-mediated oncogene transduction Annu. Rev., Neurosci. 12 1989 47 65
    • (1989) Annu. Rev., Neurosci. , vol.12 , pp. 47-65
    • Cepko, C.L.1
  • 10
    • 0001570660 scopus 로고
    • Transduction of genes using retrovirus vectors
    • F.M. Ausubel R. Brent R.E. Kingston D.D. Moore J.G. Seidman J.A. Smith K. Struhl Wiley New York
    • C.L. Cepko Transduction of genes using retrovirus vectors F.M. Ausubel R. Brent R.E. Kingston D.D. Moore J.G. Seidman J.A. Smith K. Struhl Current Protocols in Molecular Biology 1992 Wiley New York pp. (9.10) 1-9, (14.3)
    • (1992) Current Protocols in Molecular Biology
    • Cepko, C.L.1
  • 11
    • 0029591791 scopus 로고
    • The three transforming regions of SV40 T antigen are required for immortalization of primary mouse embryo fibroblasts
    • S.D. Conzen, and C.N. Cole The three transforming regions of SV40 T antigen are required for immortalization of primary mouse embryo fibroblasts Oncogene 11 1995 2295 2302
    • (1995) Oncogene , vol.11 , pp. 2295-2302
    • Conzen, S.D.1    Cole, C.N.2
  • 12
    • 0032780308 scopus 로고    scopus 로고
    • The role of the J domain of SV40 large T in cellular transformation
    • J.A. DeCaprio The role of the J domain of SV40 large T in cellular transformation Biologicals 27 1999 23 28
    • (1999) Biologicals , vol.27 , pp. 23-28
    • Decaprio, J.A.1
  • 16
    • 0026540613 scopus 로고
    • Simian virus 40 large t antigen: The puzzle, the pieces, and the emerging picture
    • E. Fanning Simian virus 40 large t antigen: the puzzle, the pieces, and the emerging picture J. Virol. 66 1992 1289 1293
    • (1992) J. Virol. , vol.66 , pp. 1289-1293
    • Fanning, E.1
  • 18
    • 0027936410 scopus 로고
    • Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity
    • J.A. Frost, A.S. Alberts, E. Sontag, K. Guan, M.C. Mumby, and J.R. Feramisco Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity Mol. Cell. Biol. 14 1994 6244 6252
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 6244-6252
    • Frost, J.A.1    Alberts, A.S.2    Sontag, E.3    Guan, K.4    Mumby, M.C.5    Feramisco, J.R.6
  • 19
    • 0023807773 scopus 로고
    • Antigenic and functional characterization of a rat central nervous system-derived cell line immortalized by a retroviral vector
    • H.M. Geller, and M. Dubois-Dalcq Antigenic and functional characterization of a rat central nervous system-derived cell line immortalized by a retroviral vector J. Cell Biol. 107 1988 1977 1986
    • (1988) J. Cell Biol. , vol.107 , pp. 1977-1986
    • Geller, H.M.1    Dubois-Dalcq, M.2
  • 20
    • 0029766815 scopus 로고    scopus 로고
    • Constitutive expression of glutamic acid decarboxylase (GAD) by striatal cell lines immortalized using the tsa58 allele of the SV40 large T antigen
    • M. Giordano, H. Takashima, M. Poltorak, H.M. Geller, and W.J. Freed Constitutive expression of glutamic acid decarboxylase (GAD) by striatal cell lines immortalized using the tsa58 allele of the SV40 large T antigen Cell Transplant 5 1996 563 575
    • (1996) Cell Transplant , vol.5 , pp. 563-575
    • Giordano, M.1    Takashima, H.2    Poltorak, M.3    Geller, H.M.4    Freed, W.J.5
  • 21
    • 0013986115 scopus 로고
    • SV40 Transformation of human diploid cells. A parallel study of viral and karyologic parameters
    • A.J. Girardi, D. Weinstein, and P.S. Moorhead SV40 Transformation of human diploid cells. A parallel study of viral and karyologic parameters Ann. Med. Exp. Biol. Fenn. 44 1966 242 254
    • (1966) Ann. Med. Exp. Biol. Fenn. , vol.44 , pp. 242-254
    • Girardi, A.J.1    Weinstein, D.2    Moorhead, P.S.3
  • 22
    • 0033988078 scopus 로고    scopus 로고
    • PRB-dependent, J domain-independent function of simian virus 40 large T Antigen in override of P53 growth suppression
    • O. Gjoerup, H. Chao, J.A. DeCaprio, and T.M. Roberts PRB-dependent, J domain-independent function of simian virus 40 large T Antigen in override of P53 growth suppression J. Virol. 74 2000 864 874
    • (2000) J. Virol. , vol.74 , pp. 864-874
    • Gjoerup, O.1    Chao, H.2    Decaprio, J.A.3    Roberts, T.M.4
  • 24
    • 0034063408 scopus 로고    scopus 로고
    • Conditionally immortalized, multipotential and multifunctional neural stem cell lines as an approach to clinical transplantation
    • J.A. Gray, G. Grigoryan, D. Virley, S. Patel, J.D. Sinden, and H. Hodges Conditionally immortalized, multipotential and multifunctional neural stem cell lines as an approach to clinical transplantation Cell Transplant 9 2000 153 168
    • (2000) Cell Transplant , vol.9 , pp. 153-168
    • Gray, J.A.1    Grigoryan, G.2    Virley, D.3    Patel, S.4    Sinden, J.D.5    Hodges, H.6
  • 25
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in tetrahymena extracts
    • C.W. Greider, and E.H. Blackburn Identification of a specific telomere terminal transferase activity in tetrahymena extracts Cell 43 1985 405 413
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 26
    • 0033786378 scopus 로고    scopus 로고
    • Rb function in cell-cycle regulation and apoptosis
    • J.W. Harbour, and D.C. Dean Rb function in cell-cycle regulation and apoptosis Nat. Cell Biol. 2 2000 E65 E67
    • (2000) Nat. Cell Biol. , vol.2
    • Harbour, J.W.1    Dean, D.C.2
  • 27
    • 0027153571 scopus 로고
    • Structure of the rat P53 tumor suppressor gene
    • J.E. Hulla, and R.P. Schneider Structure of the rat P53 tumor suppressor gene Nucleic Acids Res. 21 1993 713 717
    • (1993) Nucleic Acids Res. , vol.21 , pp. 713-717
    • Hulla, J.E.1    Schneider, R.P.2
  • 28
    • 0026712528 scopus 로고
    • Intracerebral transplantation of the A1 immortalized astrocytic cell line
    • M. Isono, H.M. Geller, M. Poltorak, and W.J. Freed Intracerebral transplantation of the A1 immortalized astrocytic cell line Res. Neurol. Neurosci. 4 1992 301 310
    • (1992) Res. Neurol. Neurosci. , vol.4 , pp. 301-310
    • Isono, M.1    Geller, H.M.2    Poltorak, M.3    Freed, W.J.4
  • 31
    • 0032103439 scopus 로고    scopus 로고
    • The J-domain family and the recruitment of chaperone power
    • W.L. Kelley The J-domain family and the recruitment of chaperone power Trends Biochem. Sci. 23 1998 222 227
    • (1998) Trends Biochem. Sci. , vol.23 , pp. 222-227
    • Kelley, W.L.1
  • 32
    • 0027535098 scopus 로고
    • Association of P53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 t-antigen mutants bearing internal overlapping deletion mutations
    • T.D. Kierstead, and M.J. Tevethia Association of P53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 t-antigen mutants bearing internal overlapping deletion mutations J. Virol. 67 1993 1817 1829
    • (1993) J. Virol. , vol.67 , pp. 1817-1829
    • Kierstead, T.D.1    Tevethia, M.J.2
  • 33
    • 0028277921 scopus 로고
    • Expression of wild-type and mutant simian virus 40 large tumor antigens in villus-associated enterocytes of transgenic mice
    • S.H. Kim, K.A. Roth, C.M. Coopersmith, J.M. Pipas, and J.I. Gordon Expression of wild-type and mutant simian virus 40 large tumor antigens in villus-associated enterocytes of transgenic mice Proc. Natl. Acad. Sci. U. S. A. 91 1994 6914 6918
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 6914-6918
    • Kim, S.H.1    Roth, K.A.2    Coopersmith, C.M.3    Pipas, J.M.4    Gordon, J.I.5
  • 35
    • 0035863048 scopus 로고    scopus 로고
    • Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large t antigen
    • H.Y. Kim, B.Y. Ahn, and Y. Cho Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large t antigen EMBO J. 20 2001 295 304
    • (2001) EMBO J. , vol.20 , pp. 295-304
    • Kim, H.Y.1    Ahn, B.Y.2    Cho, Y.3
  • 36
    • 0030950046 scopus 로고    scopus 로고
    • Telomere structure and telomerase expression during mouse development and tumorigenesis
    • D. Kipling Telomere structure and telomerase expression during mouse development and tumorigenesis Eur. J. Cancer 33 1997 792 800
    • (1997) Eur. J. Cancer , vol.33 , pp. 792-800
    • Kipling, D.1
  • 37
    • 0018348655 scopus 로고
    • T antigen is bound to a host protein in SV40-transformed cells
    • D.P. Lane, and L.V. Crawford T antigen is bound to a host protein in SV40-transformed cells Nature 278 1979 261 263
    • (1979) Nature , vol.278 , pp. 261-263
    • Lane, D.P.1    Crawford, L.V.2
  • 39
    • 0018760324 scopus 로고
    • Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells
    • D.I. Linzer, and A.J. Levine Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells Cell 17 1979 43 52
    • (1979) Cell , vol.17 , pp. 43-52
    • Linzer, D.I.1    Levine, A.J.2
  • 40
    • 0036285473 scopus 로고    scopus 로고
    • Differentiation of the RN33B cell line into forebrain projection neurons after transplantation into the neonatal rat brain
    • C. Lundberg, U. Englund, D. Trono, A. Bjorklund, and K. Wictorin Differentiation of the RN33B cell line into forebrain projection neurons after transplantation into the neonatal rat brain Exp. Neurol. 175 2002 370 387
    • (2002) Exp. Neurol. , vol.175 , pp. 370-387
    • Lundberg, C.1    Englund, U.2    Trono, D.3    Bjorklund, A.4    Wictorin, K.5
  • 42
    • 0016608304 scopus 로고
    • Simian virus 40 functions required for the establishment and maintenance of malignant transformation
    • R.G. Martin, and J.Y. Chou Simian virus 40 functions required for the establishment and maintenance of malignant transformation J. Virol. 15 1975 599 612
    • (1975) J. Virol. , vol.15 , pp. 599-612
    • Martin, R.G.1    Chou, J.Y.2
  • 43
    • 0026093164 scopus 로고
    • Cellular localization and cell cycle regulation by a temperature- sensitive P53 protein
    • J. Martinez, I. Georgoff, and A.J. Levine Cellular localization and cell cycle regulation by a temperature-sensitive P53 protein Genes Dev. 5 1991 151 159
    • (1991) Genes Dev. , vol.5 , pp. 151-159
    • Martinez, J.1    Georgoff, I.2    Levine, A.J.3
  • 45
    • 0025111068 scopus 로고
    • Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of P53
    • D. Michalovitz, O. Halevy, and M. Oren Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of P53 Cell 62 1990 671 680
    • (1990) Cell , vol.62 , pp. 671-680
    • Michalovitz, D.1    Halevy, O.2    Oren, M.3
  • 47
    • 0028046020 scopus 로고
    • Short-term immunosuppression enhances the survival of intracerebral grafts of A7-immortalized glial cells
    • G.S. Okoye, W.J. Freed, and H.M. Geller Short-term immunosuppression enhances the survival of intracerebral grafts of A7-immortalized glial cells Exp. Neurol. 128 1994 191 201
    • (1994) Exp. Neurol. , vol.128 , pp. 191-201
    • Okoye, G.S.1    Freed, W.J.2    Geller, H.M.3
  • 48
    • 0028788241 scopus 로고
    • Migration of A7 immortalized astrocytic cells grafted into the adult rat striatum
    • G.S. Okoye, E.M. Powell, and H.M. Geller Migration of A7 immortalized astrocytic cells grafted into the adult rat striatum J. Comp. Neurol. 362 1995 524 534
    • (1995) J. Comp. Neurol. , vol.362 , pp. 524-534
    • Okoye, G.S.1    Powell, E.M.2    Geller, H.M.3
  • 49
    • 0025103372 scopus 로고
    • Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A
    • D.C. Pallas, L.K. Shahrik, B.L. Martin, S. Jaspers, T.B. Miller, D.L. Brautigan, and T.M. Roberts Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A Cell 60 1990 167 176
    • (1990) Cell , vol.60 , pp. 167-176
    • Pallas, D.C.1    Shahrik, L.K.2    Martin, B.L.3    Jaspers, S.4    Miller, T.B.5    Brautigan, D.L.6    Roberts, T.M.7
  • 52
    • 0033046766 scopus 로고    scopus 로고
    • The simian virus 40 small-t and large-t antigens jointly regulate cell cycle reentry in human fibroblasts
    • A. Porras, S. Gaillard, and K. Rundell The simian virus 40 small-t and large-t antigens jointly regulate cell cycle reentry in human fibroblasts J. Virol. 73 1999 3102 3107
    • (1999) J. Virol. , vol.73 , pp. 3102-3107
    • Porras, A.1    Gaillard, S.2    Rundell, K.3
  • 53
    • 0027955429 scopus 로고
    • The amino-terminal functions of the simian virus 40 large t antigen are required to overcome wild-type P53-mediated growth arrest of cells
    • R.S. Quartin, C.N. Cole, J.M. Pipas, and A.J. Levine The amino-terminal functions of the simian virus 40 large t antigen are required to overcome wild-type P53-mediated growth arrest of cells J. Virol. 68 1994 1334 1341
    • (1994) J. Virol. , vol.68 , pp. 1334-1341
    • Quartin, R.S.1    Cole, C.N.2    Pipas, J.M.3    Levine, A.J.4
  • 54
    • 0025833294 scopus 로고
    • Region-specific differentiation of the hippocampal stem cell line HiB5 upon implantation into the developing mammalian brain
    • P.J. Renfranz, M.G. Cunningham, and R.D. McKay Region-specific differentiation of the hippocampal stem cell line HiB5 upon implantation into the developing mammalian brain Cell 66 1991 713 729
    • (1991) Cell , vol.66 , pp. 713-729
    • Renfranz, P.J.1    Cunningham, M.G.2    McKay, R.D.3
  • 56
    • 0020079972 scopus 로고
    • Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 Kd cellular protein in transformed cells
    • P. Sarnow, Y.S. Ho, J. Williams, and A.J. Levine Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 Kd cellular protein in transformed cells Cell 28 1982 387 394
    • (1982) Cell , vol.28 , pp. 387-394
    • Sarnow, P.1    Ho, Y.S.2    Williams, J.3    Levine, A.J.4
  • 57
    • 0034682721 scopus 로고    scopus 로고
    • Cellular senescence: Mitotic clock or culture shock?
    • C.J. Sherr, and R.A. DePinho Cellular senescence: Mitotic clock or culture shock? Cell 102 2000 407 410
    • (2000) Cell , vol.102 , pp. 407-410
    • Sherr, C.J.1    Depinho, R.A.2
  • 58
    • 0011137203 scopus 로고
    • Retroviral vectors for the study of neuroembryology: Immortalization of neural cells
    • M.G. Kaplit A.D. Loewy Academic Press New York
    • E.F. Snyder Retroviral vectors for the study of neuroembryology: immortalization of neural cells M.G. Kaplit A.D. Loewy Viral Vectors: Tools for Analysis and Genetic Manipulation of the Nervous System 1995 Academic Press New York 435 475
    • (1995) Viral Vectors: Tools for Analysis and Genetic Manipulation of the Nervous System , pp. 435-475
    • Snyder, E.F.1
  • 60
    • 0029989279 scopus 로고    scopus 로고
    • Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins P130 and P107
    • H. Stubdal, J. Zalvide, and J.A. DeCaprio Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins P130 and P107 J. Virol. 70 1996 2781 2788
    • (1996) J. Virol. , vol.70 , pp. 2781-2788
    • Stubdal, H.1    Zalvide, J.2    Decaprio, J.A.3
  • 61
    • 0023869670 scopus 로고
    • Requirements for immortalization of primary mouse embryo fibroblasts probed with mutants bearing deletions in the 3′ end of SV40 gene a
    • M.J. Tevethia, J.M. Pipas, T. Kierstead, and C. Cole Requirements for immortalization of primary mouse embryo fibroblasts probed with mutants bearing deletions in the 3′ end of SV40 gene A Virology 162 1988 76 89
    • (1988) Virology , vol.162 , pp. 76-89
    • Tevethia, M.J.1    Pipas, J.M.2    Kierstead, T.3    Cole, C.4
  • 62
    • 0025024371 scopus 로고
    • Dissociation of Rb-binding and anchorage-independent growth from immortalization and tumorigenicity using SV40 mutants producing n-terminally truncated large T antigens
    • D.L. Thompson, D. Kalderon, A.E. Smith, and M.J. Tevethia Dissociation of Rb-binding and anchorage-independent growth from immortalization and tumorigenicity using SV40 mutants producing n-terminally truncated large T antigens Virology 178 1990 15 34
    • (1990) Virology , vol.178 , pp. 15-34
    • Thompson, D.L.1    Kalderon, D.2    Smith, A.E.3    Tevethia, M.J.4
  • 64
    • 0031889823 scopus 로고    scopus 로고
    • A truncated SV40 large T antigen lacking the P53 binding domain overcomes P53-induced growth arrest and immortalizes primary mesencephalic cells
    • M.E. Truckenmiller, C. Tornatore, R.D. Wright, O. Dillon-Carter, S. Meiners, H.M. Geller, and W.J. Freed A truncated SV40 large T antigen lacking the P53 binding domain overcomes P53-induced growth arrest and immortalizes primary mesencephalic cells Cell Tissue Res. 291 1998 175 189
    • (1998) Cell Tissue Res. , vol.291 , pp. 175-189
    • Truckenmiller, M.E.1    Tornatore, C.2    Wright, R.D.3    Dillon-Carter, O.4    Meiners, S.5    Geller, H.M.6    Freed, W.J.7
  • 67
    • 0027930072 scopus 로고
    • Frequent and specific mutations of the rat P53 gene in hepatocarcinomas induced by tamoxifen
    • P.M. Vancutsem, P. Lazarus, and G.M. Williams Frequent and specific mutations of the rat P53 gene in hepatocarcinomas induced by tamoxifen Cancer Res. 54 1994 3864 3867
    • (1994) Cancer Res. , vol.54 , pp. 3864-3867
    • Vancutsem, P.M.1    Lazarus, P.2    Williams, G.M.3
  • 68
    • 0028016451 scopus 로고
    • Transrepression of RNA polymerase II promoters by the simian virus 40 small t antigen
    • W.B. Wang, I. Bikel, E. Marsilio, D. Newsome, and D.M. Livingston Transrepression of RNA polymerase II promoters by the simian virus 40 small t antigen J. Virol. 68 1994 6180 6187
    • (1994) J. Virol. , vol.68 , pp. 6180-6187
    • Wang, W.B.1    Bikel, I.2    Marsilio, E.3    Newsome, D.4    Livingston, D.M.5
  • 70
    • 0030978765 scopus 로고    scopus 로고
    • The DNA structures at the ends of eukaryotic chromosomes
    • R.J. Wellinger, and D. Sen The DNA structures at the ends of eukaryotic chromosomes Eur. J. Cancer 33 1997 735 749
    • (1997) Eur. J. Cancer , vol.33 , pp. 735-749
    • Wellinger, R.J.1    Sen, D.2
  • 71
    • 0033603882 scopus 로고    scopus 로고
    • SV40 small t antigen enhances progression to >g2 during lytic infection
    • B. Whalen, J. Laffin, T.D. Friedrich, and J.M. Lehman SV40 small t antigen enhances progression to >G2 during lytic infection Exp. Cell Res. 251 1999 121 127
    • (1999) Exp. Cell Res. , vol.251 , pp. 121-127
    • Whalen, B.1    Laffin, J.2    Friedrich, T.D.3    Lehman, J.M.4
  • 72
    • 0034589738 scopus 로고    scopus 로고
    • Immortalized neural cell lines for CNS transplantation
    • S.R. Whittemore, and S.M. Onifer Immortalized neural cell lines for CNS transplantation Prog. Brain Res. 127 2000 49 65
    • (2000) Prog. Brain Res. , vol.127 , pp. 49-65
    • Whittemore, S.R.1    Onifer, S.M.2
  • 73
    • 0030917098 scopus 로고    scopus 로고
    • Proliferative lifespan checkpoints: Cell-type specificity and influence on tumour biology
    • D. Wynford-Thomas Proliferative lifespan checkpoints: cell-type specificity and influence on tumour biology Eur. J. Cancer 33 1997 716 726
    • (1997) Eur. J. Cancer , vol.33 , pp. 716-726
    • Wynford-Thomas, D.1
  • 75
    • 0031935825 scopus 로고    scopus 로고
    • The J domain of simian virus 40 large t antigen is required to functionally inactivate RB family proteins
    • J. Zalvide, H. Stubdal, and J.A. DeCaprio The J domain of simian virus 40 large t antigen is required to functionally inactivate RB family proteins Mol. Cell. Biol. 18 1998 1408 1415
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 1408-1415
    • Zalvide, J.1    Stubdal, H.2    Decaprio, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.