Digestive and absorptive processes of alimentary fat;Les processus digestifs et absorptifs des lipides alimentaires

Gastroenterologie Clinique et Biologique

Volumn 28, Issue 12, 2004, Pages 1257-1266

  Marcil, Valérie ^a,b   Peretti, Noël ^a,b   Delvin, Edgard ^a,b   Levy, Emile ^a,b  

^a UNIVERSITY OF MONTREAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; CHYLOMICRON;

ABETALIPOPROTEINEMIA; ANATOMY; CYTOSOL; DIGESTION; DIGESTIVE SYSTEM; EMULSION; HUMAN; HYPOBETALIPOPROTEINEMIA; INTESTINE ABSORPTION; INTESTINE CELL; INTESTINE WALL; LIPID METABOLISM; REVIEW;

EID: 11244296897     PISSN: 03998320     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0399-8320(04)95219-0     Document Type: Review

References (87)

1. rd ed. New-York: Raven Press, 1994;2:1577-622.
2. Klippert P, Borm P, Noordhoek J. Prediction of intestinal first-pass effect of phenacetin in the rat from enzyme kinetic data - correlation with in vivo data using mucosal blood flow. Biochem Pharmacol 1982;31:2545-8.
3. Tang VW, Goodenough DA. Paracellular ion channel at the tight junction. Biophys J 2003;84:1660-73.
4. Mansbach CM, II, Dowell RF, Pritchett D. Portal transport of absorbed lipids in rats. Am J Physiol 1991;261:G530-G538.
5. Farquhar MG, Palade GE. Junctional complexes in various epithelia. J Cell Biol 1963;17:375-412.
6. Naim HY, Sterchi EE, Lentze MJ. Structure, biosynthesis, and glycosylation of human small intestinal maltase-glucoamylase. J Biol Chem 1988;263:19709-17.
7. Tobey N, Heizer W, Yeh R, Huang TI, Hoffner C. Human intestinal brush border peptidases. Gastroenterology 1985;88:913-26.
8. Ahnen DJ, Mircheff AK, Santiago NA, Yoshioka C, Gray GM. Intestinal surface aminooligopeptidase. Distinct molecular forms during assembly on intracellular membranes in vivo. J Biol Chem 1983; 258:5960-6.
9. Goda T. Regulation of the expression of carbohydrate digestion/ absorption-related genes. Br J Nutr 2000;84 Suppl 2:S245-S248.
10. Levy E, Menard D, Delvin E, Stan S, Mitchell G, Lambert M, et al. The polymorphism at codon 54 of the FABP2 gene increases fat absorption in human intestinal expiants. J Biol Chem 2001;276:39679-84.
11. Thomson AB, McIntyre Y, MacLeod J, Keelan M. Adaptation of co-ionic uptake of hexoses and lipids following ileal resection: effect of variations in the fat content of the diet. Digestion 1986;35:89-94.
12. Wilson MD, Rudel LL. Review of cholesterol absorption with emphasis on dietary and biliary cholesterol. J Lipid Res 1994;35:943-55.
13. Istvan ES, Deisenhofer J. The structure of the catalytic portion of human HMG-CoA reductase. Biochim Biophys Acta 2000;1529:9-18.
14. Moreau H, Laugier R, Gargouri Y, Ferrato F, Verger R. Human preduodenal lipase is entirely of gastric fundic origin. Gastroenterology 1988;95:1221-6.
15. Abrams CK, Hamosh M, Lee TC, Ansher AF, Collen MJ, Lewis JH, et al. Gastric lipase: localization in the human stomach. Gastroenterology 1988;95:1460-4.
16. Liddle RA, Goldfine ID, Rosen MS, Taplitz RA, Williams JA. Cholecystokinin bioactivity in human plasma. Molecular forms, responses to feeding, and relationship to gallbladder contraction. J Clin Invest 1985;75:1144-52.
17. Hofmann AF, Borgstrom B. Hydrolysis of long-chain monoglycerides in micellar solution by pancreatic lipase. Biochim Biophys Acta 1963;70:317-31.
18. Sternby B, Nilsson A, Melin T, Borgstrom B. Pancreatic lipolytic enzymes in human duodenal contents. Radioimmunoassay compared with enzyme activity. Scand J Gastroenterol 1991;26:859-66.
19. Mackay K, Starr JR, Lawn RM, Ellsworth JL. Phosphatidylcholine hydrolysis is required for pancreatic cholesterol esterase- and phospholipase A2-facilitated cholesterol uptake into intestinal Caco-2 cells. J Biol Chem 1997;272:13380-9.
20. Reynier MO, Lafont H, Crotte C, Sauve P, Gerolami A. Intestinal cholesterol uptake: comparison between mixed micelles containing lecithin or lysolecithin. Lipids 1985;20:145-50.
21. Westergaard H, Dietschy JM. The mechanism whereby bile acid micelles increase the rate of fatty acid and cholesterol uptake into the intestinal mucosal cell. J Clin Invest 1976;58:97-108.
22. Wilson FA, Sallee VL, Dietschy JM. Unstirred water layers in intestine: rate determinant of fatty acid absorption from micellar solutions. Science 1971;174:1031-3.
23. Thomson AB, Dietschy JM. Experimental demonstration of the effect of the unstirred water layer on the kinetic constants of the membrane transport of D-glucose in rabbit jejunum. J Membr Biol 1980;54:221-9.
24. Thomson AB, Schoeller C, Keelan M, Smith L, Clandinin MT. Lipid absorption: passing through the unstirred layers, brush-border membrane, and beyond. Can J Physiol Pharmacol 1993;71:531-55.
25. Levy E. Digestion and absorption of carbohydrates, fat and proteins. In: Rathaike RN, ed. Small Bowel Disorders. London (UK): Hodder Arnold, 2000:162-82.
26. Besnard P, Niot I, Bernard A, Carlier H. Cellular and molecular aspects of fat metabolism in the small intestine. Proc Nutr Soc 1996; 55:19-37.
27. Hamilton JA, Kamp F. How are free fatty acids transported in membranes? Is it by proteins or by free diffusion through the lipids? Diabetes 1999;48:2255-69.
28. Schaffer JE. Fatty acid transport: the roads taken. Am J Physiol Endocrinol Metab 2002;282:E239-46.
29. Stahl A, Hirsch DJ, Gimeno RE, Punreddy S, Ge P, Watson N, et al. Identification of the major intestinal fatty acid transport protein. Mol Cell 1999;4:299-308.
30. Veerkamp JH, van Kuppeveit TH, Maatman RG, Prinsen CF. Structural and functional aspects of cytosolic fatty acid-binding proteins. Prostaglandins Leukot Essent Fatty Acids 1993;49:887-906.
31. Alpers DH, Bass NM, Engle MJ, DeSchryver-Kecskemeti K. Intestinal fatty acid binding protein may favor differential apical fatty acid binding in the intestine. Biochim Biophys Acta 2000;1483:352-62.
32. Glatz JF, van der Vusse GJ. Cellular fatty acid-binding proteins: current concepts and future directions. Mol Cell Biochem 1990;98:237-51.
33. Sfeir Z, Ibrahimi A, Amri E, Grimaldi P, Abumrad N. Regulation of FAT/CD36 gene expression: further evidence in support of a role of the protein in fatty acid binding/transport. Prostaglandins Leukot Essent Fatty Acids 1997;57:17-21.
34. Chen M, Yang Y, Braunstein E, Georgeson KE, Harmon CM. Gut expression and regulation of FAT/CD36: possible role in fatty acid transport in rat enterocytes. Am J Physiol Endocrinol Metab 2001;281:E916-E923.
35. Howles PN, Carter CP, Hui DY. Dietary free and esterified cholesterol absorption in cholesterol esterase (bile salt-stimulated lipase) gene-targeted mice. J Biol Chem 1996;271:7196-202.
36. Acton S, Rigotti A, Landschulz KT, Xu S, Hobbs HH, Krieger M. Identification of scavenger receptor SR-BI as a high density lipoprotein receptor. Science 1996;271:518-20.
37. Trigatti BL, Krieger M, Rigotti A. Influence of the HDL receptor SR-BI on lipoprotein metabolism and atherosclerosis. Arterioscler Thromb Vasc Biol 2003;23:1732-8.
38. Ishibashi S, Brown MS, Goldstein JL, Gerard RD, Hammer RE, Herz J. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J Clin Invest 1993;92:883-93.
39. Kozarsky KF, Donahee MH, Click JM, Krieger M, Rader DJ. Gene transfer and hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse. Arterioscler Thromb Vasc Biol 2000;20:721-7.
40. Cai SF, Kirby RJ, Howles PN, Hui DY. Differentiation-dependent expression and localization of the class B type I scavenger receptor in intestine. J Lipid Res 2001;42:902-9.
41. Hauser H, Dyer JH, Nandy A, Vega MA, Werder M, Bieliauskaite E, et al. Identification of a receptor mediating absorption of dietary cholesterol in the intestine. Biochemistry 1998;37:17843-50.
42. Altmann SW, Davis HR, Jr., Yao X, Laverty M, Compton DS, Zhu LJ, et al. The identification of intestinal scavenger receptor class B, type I (SR-BI) by expression cloning and its role in cholesterol absorption. Biochim Biophys Acta 2002;1580:77-93.
43. Levy E, Menard D, Sue I, Delvin E, Marcil V, Brissette L, et al. Ontogeny, immunolocalisation, distribution and function of SR-BI in the human intestine. J Cell Sci 2004;117:327-37.
44. Mardones P, Quinones V, Amigo L, Moreno M, Miquel JF, Schwarz M, et al. Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type 1-deficient mice. J Lipid Res 2001;42:170-80.
45. Cai L, Eckhardt ER, Shi W, Zhao Z, Nasser M, de Villiers WJ, et al. Scavenger receptor class B type I reduces cholesterol absorption in cultured enterocyte CaCo-2 cells. J Lipid Res 2004;45:253-62.
46. Repa JJ, Turley SD, Lobaccaro JA, Medina J, Li L, Lustig K, et al. Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers. Science 2000;289:1524-9.
47. Murthy S, Born E, Mathur SN, Field FJ. LXR/RXR activation enhances basolateral efflux of cholesterol in CaCo-2 cells. J Lipid Res 2002;43:1054-64.
48. Mulligan JD, Flowers MT, Tebon A, Bitgood JJ, Wellington C, Hayden MR, et al. ABCA1 is essential for efficient basolateral cholesterol efflux during the absorption of dietary cholesterol in chickens. J Biol Chem 2003;278:13356-66.
49. Plosch T, Kok T, Bloks VW, Smit MJ, Havinga R, Chimini G, et al. Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1. J Biol Chem 2002;277:33870-7.
50. Dube N, Delvin E, Yotov W, Garofalo C, Bendayan M, Veerkamp JH, et al. Modulation of intestinal and liver fatty acid-binding proteins in Caco-2 cells by lipids, hormones and cytokines. J Cell Biochem 2001; 81:613-20.
51. Woolf TB, Tychko M. Simulations of fatty acid-binding proteins. II. Sites for discrimination of monounsaturated ligands. Biophys J 1998; 74:694-707.
52. Corsico B, Cistola DP, Frieden C, Storch J. The helical domain of intestinal fatty acid binding protein is critical for collisional transfer of fatty acids to phospholipid membranes. Proc Natl Acad Sci USA 1998;95:12174-8.
53. Kaikaus RM, Bass NM, Ockner RK. Functions of fatty acid binding proteins. Experientia 1990;46:617-30.
54. Murphy EJ. Sterol carrier protein-2 expression increases NBD-stearate uptake and cytoplasmic diffusion in L cells. Am J Physiol 1998; 275:G237-G243.
55. Veerkamp JH. Fatty acid transport and fatty acid-binding proteins. Proc Nutr Soc 1995;54:23-37.
56. Buhman KK, Smith SJ, Stone SJ, Repa JJ, Wong JS, Knapp FF, Jr., et al. DGAT1 is not essential for intestinal triacylglycerol absorption or chylomicron synthesis. J Biol Chem 2002;277:25474-9.
57. Cao J, Lockwood J, Burn P, Shi Y. Cloning and functional characterization of a mouse intestinal acyl-CoA:monoacylglycerol acyltransferase, MGAT2. J Biol Chem 2003;278:13860-6.
58. Senior JR, Isselbacher KJ. Direct esterification of monoglycerides with palmityl coenzyme A by intestinal epithelial subcellular fractions. J Biol Chem 1962;237:1454-9.
59. Lee DP, Deonarine AS, Kienetz M, Zhu Q, Skrzypczak M, Chan M, et al. A novel pathway for lipid biosynthesis: the direct acylation of glycerol. J Lipid Res 2001;42:1979-86.
60. Cao J, Burn P, Shi Y. Properties of the mouse intestinal acyl-CoA:monoacylglycerol acyltransferase, MGAT2. J Biol Chem 2003; 278:25657-63.
61. Parthasarathy S, Subbaiah PV, Ganguly J. The mechanism of intestinal absorption of phosphatidylcholine in rats. Biochem J 1974; 140:503-8.
62. Buhman KF, Accad M, Farese RV. Mammalian acyl-CoA:cholesterol acyltransferases. Biochim Biophys Acta 2000;1529:142-54.
63. Dawson PA, Rudel LL. Intestinal cholesterol absorption. Curr Opin Lipidol 1999;10:315-20.
64. Davidson NO, Shelness GS. APOLIPOPROTEIN B: mRNA editing, lipoprotein assembly, and presecretory degradation. Annu Rev Nutr 2000;20:169-93.
65. Levy E, Marcel YL, Milne RW, Grey VL, Roy CC. Absence of intestinal synthesis of apolipoprotein B-48 in two cases of abetalipoproteinemia. Gastroenterology 1987;93:1119-26.
66. Teng B, Burant CF, Davidson NO. Molecular cloning of an apolipoprotein B messenger RNA editing protein. Science 1993;260:1816-9.
67. Wetterau JR, Aggerbeck LP, Bouma ME, Eisenberg C, Munck A, Hermier M, et al. Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia. Science 1992;258:999-1001.
68. Wetterau JR, Lin MC, Jamil H. Microsomal triglyceride transfer protein. Biochim Biophys Acta 1997;1345:136-50.
69. Hussain MM, Kancha RK, Zhou Z, Luchoomun J, Zu H, Bakillah A. Chylomicron assembly and catabolism: role of apolipoproteins and receptors. Biochim Biophys Acta 1996;1300:151-70.
70. Havel RJ. Lipid transport function of lipoproteins in blood plasma. Am J Physiol 1987;253:E1-E5.
71. Mahley RW, Bennett BD, Morre DJ, Gray ME, Thistlethwaite W, LeQuire VS. Lipoproteins associated with the Golgi apparatus isolated from epithelial cells of rat small intestine. Lab Invest 1971;25:435-44.
72. Magun AM, Brasitus TA, Glickman RM. Isolation of high density lipoproteins from rat intestinal epithelial cells. J Clin Invest 1985; 75:209-18.
73. Levy E, Mehran M, Seidman E. Caco-2 cells as a model for intestinal lipoprotein synthesis and secretion. FASEB J 1995;9:626-35.
74. Sharp D, Ricci B, Kienzle B, Lin MC, Wetterau JR. Human microsomal triglyceride transfer protein large subunit gene structure. Biochemistry 1994;33:9057-61.
75. Berriot-Varoqueaux N, Aggerbeck LP, Samson-Bouma M, Wetterau JR. The role of the microsomal triglygeride transfer protein in abetalipoproteinemia. Annu Rev Nutr 2000;20:663-97.
76. Gordon DA, Jamil H. Progress towards understanding the role of microsomal triglyceride transfer protein in apolipoprotein-B lipoprotein assembly. Biochim Biophys Acta 2000;1486:72-83.
77. Levy E. The genetic basis of primary disorders of intestinal fat transport. Clin Invest Med 1996;19:317-24.
78. Berriot-Varoqueaux N, Aggerbeck LP, Samson-Bouma M. Microsomal triglyceride transfer protein and abetalipoproteinemia. Ann Endocrinol (Paris) 2000;61:125-9.
79. Wu J, Kim J, Li Q, Kwok PY, Cole TG, Cefalu B, et al. Known mutations of apoB account for only a small minority of hypobetalipoproteinemia. J Lipid Res 1999;40:955-9.
80. Pulai JI, Neuman RJ, Groenewegen AW, Wu J, Schonfeld G. Genetic heterogeneity in familial hypobetalipoproteinemia: linkage and non-linkage to the apoB gene in Caucasian families. Am J Med Genet 1998;76:79-86.
81. Yuan B, Neuman R, Duan SH, Weber JL, Kwok PY, Saccone NL, et al. Linkage of a gene for familial hypobetalipoproteinemia to chromosome 3p21.1-22. Am J Hum Genet 2000;66:1699-704.
82. Neuman RJ, Yuan B, Gerhard DS, Liu KY, Yue P, Duan S, et al. Replication of linkage of familial hypobetalipoproteinemia to chromosome 3p in six kindreds. J Lipid Res 2002;43:407-15.
83. Schonfeld G. Familial hypobetalipoproteinemia: a review. J Lipid Res 2003;44:878-83.
84. Ohashi K, Ishibashi S, Yamamoto M, Osuga J, Yazaki Y, Yukawa S, et al. A truncated species of apolipoprotein B (B-38.7) in a patient with homozygous hypobetalipoproteinemia associated with diabetes mellitus. Arterioscler Thromb Vasc Biol 1998;18:1330-4.
85. Levy E, Roy CC, Thibault L, Bonin A, Brochu P, Seidman EG. Variable expression of familial heterozygous hypobetalipoproteinemia: transient malabsorption during infancy. J Lipid Res 1994;35:2170-7.
86. Levy E, Marcel Y, Deckelbaum RJ, Milne R, Lepage G, Seidman E, et al. Intestinal apoB synthesis, lipids, and lipoproteins in chylomicron retention disease. J Lipid Res 1987;28:1263-74.
87. Jones B, Jones EL, Bonney SA, Patel HN, Mensenkamp AR, Eichenbaum-Voline S, et al. Mutations in a Sari GTPase of COPII vesicles are associated with lipid absorption disorders. Nat Genet 2003;34:29-31.