Adenine deoxynucleotides fludarabine and cladribine induce apoptosis in a CD95/Fas receptor, FADD and caspase-8-independent manner by activation of the mitochondrial cell death pathway

Oncogene

Volumn 23, Issue 58, 2004, Pages 9408-9418

  Klöpfer, Antje ^a   Hasenjäger, Anne ^a   Belka, Claus ^b   Schulze Osthoff, Klaus ^c   Dörken, Bernd ^a   Daniel, Peter T ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

Author keywords

2CdA; Apoptosis; Bcl 2; Caspase 8; CD95 Fas; FADD; FAraA

Indexed keywords

ADENINE DEOXYNUCLEOSIDE; ADENINE DEOXYNUCLEOTIDE; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; CASPASE 8; CASPASE 9; CLADRIBINE; CYTOCHROME C; DEATH RECEPTOR; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FAS RECEPTOR; FLUDARABINE; NUCLEOSIDE ANALOG; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVATION; GENE INDUCTION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LYMPHOID CELL; LYMPHOPROLIFERATIVE DISEASE; MITOCHONDRION; MOLT 3 GENE; MOLT 4 GENE; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTO ONCOGENE; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; APOPTOSIS; CASPASE 8; CASPASES; CELL LINE, TUMOR; CLADRIBINE; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HUMANS; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-BCL-2; VIDARABINE;

EID: 11244296196     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207975     Document Type: Article

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