In vivo effects of CpG oligodeoxynucleotide on Eimeria infection in chickens

Avian Diseases

Volumn 48, Issue 4, 2004, Pages 783-790

  Dalloul, Rami A ^a,b   Lillehoj, Hyun S ^a   Okamura, Masashi ^a   Xie, Hang ^b   Min, Wongi ^a,c   Ding, Xicheng ^a   Heckert, Robert A ^b  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c Sunchon National University   (South Korea)

Author keywords

Chicken; Coccidiosis; CpG; Eimeria; Immunomodulation; Oligodeoxynucleotides

Indexed keywords

ANIMALIA; AVES; EIMERIA; GALLUS GALLUS; MAMMALIA;

EID: 11244250963     PISSN: 00052086     EISSN: None     Source Type: Journal    
DOI: 10.1637/7154-010704R     Document Type: Article

References (33)

1. Brown, W. C., D. M. Estes, S. E. Chantler, K. A. Kegerreis, and C. E. Suarez. DNA and a CpG oligonucleotide derived from Babesia bovis are mitogenic for bovine B cells. Infect. Immun. 66:5423-5432. 1998.
2. Dalloul, R. A., H. S. Lillehoj, U. Babu, R. Raybourne, D. Klinman, and R. Heckert. In ovo immunomodulatory effects of CpG-containing oligodeoxynucleotides in Eimeria-infected chickens. Poult. Sci. 82 (Suppl. 1):8. 2003.
3. Dalloul, R. A., H. S. Lillehoj, T. A. Shellem, and J. A. Doerr. Intestinal immunomodulation by vitamin A deficiency and Lactobacillus-based probiotic in Eimeria acervulina-infected broiler chickens. Avian Dis. 47:1313-1320. 2003.
4. Dittmer, U., and A. R. Olbrich. Treatment of infectious diseases with immunostimulatory oligodeoxynucleotides containing CpG motifs. Curr. Opin. Microbiol. 6:472-477. 2003.
5. Elkins, K. L., T. R. Rhinehart-Jones, S. Stibitz, J. S. Conover, and D. M. Klinman. Bacterial DNA containing CpG motifs stimulates lymphocyte-dependent protection of mice against lethal infection with intracellular bacteria. J. Immunol. 162:2291-2298. 1999.
6. Gomis, S., L. Babiuk, D. L. Godson, B. Allan, T. Thrush, H. Townsend, P. Willson, E. Waters, R. Hecker, and A. Potter. Protection of chickens against Escherichia coli infections by DNA containing CpG motifs. Infect. Immun. 71:857-863. 2003.
7. Gramzinski, R. A., D. L. Doolan, M. Sedegah, H. L. Davis, A. M. Krieg, and S. L. Hoffman. Interleukin-12-and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice. Infect. Immun. 69:1643-1649. 2001.
8. Hartmann, G., and A. M. Krieg. Mechanism and function of a newly identified CpG DNA motif in human primary B cells. J. Immunol. 164:944-953. 2000.
9. He, H., T. L. Crippen, M. B. Farnell, and M. H. Kogut. Identification of CpG oligodeoxynucleotide motifs that stimulate nitric oxide and cytokine production in avian macrophage and peripheral blood mononuclear cells. Dev. Comp. Immunol. 27:621-627. 2003.
10. Janeway, C. A., and R. Medzhitov. Innate immune recognition. Annu. Rev. Immunol. 20:197-216. 2002.
11. Kamstrup, S., D. Verthelyi, and D. M. Klinman. Response of porcine peripheral blood mononuclear cells to CpG-containing oligodeoxynucleotides. Vet. Microbiol. 78:353-362. 2001.
12. Klinman, D. M., J. Conover, and C. Coban. Repeated administration of synthetic oligodeoxynucleotides expressing CpG motifs provides long-term protection against bacterial infection. Infect. Immun. 67:5658-5663. 1999.
13. Klinman, D. M., A. K. Yi, S. L. Beaucage, J. Conover, and A. M. Krieg. CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma. Proc. Natl. Acad. Sci. USA 93:2879-2883. 1996.
14. Krieg, A. M. CpG motifs in bacterial DNA and their immune effects. Annu. Rev. Immunol. 20:709-760. 2002.
15. Krieg, A. M., L. Love-Homan, A. K. Yi, and J. T. Harty. CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge. J. Immunol. 161:2428-2434. 1998.
16. Krieg, A. M., A. K. Yi, S. Matson, T. J. Waldschmidt, G. A. Bishop, R. Teasdale, G. A. Koretzky, and D. M. Klinman. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 374:546-549. 1995.
17. Lillehoj, H. S. Influence of inoculation dose, inoculation schedule, chicken age, and host genetics on disease susceptibility and development of resistance to Eimeria tenella infection. Avian Dis. 32:437-444. 1988.
18. Lillehoj, H. S., K. D. Choi, M. C. Jenkins, V. N. Vakharia, K. D. Song, J. Y. Han, and E. P. Lillehoj. A recombinant Eimeria protein inducing interferon-gamma production: comparison of different gene expression systems and immunization strategies for vaccination against coccidiosis. Avian Dis. 44:379-389. 2000.
19. Lillehoj, H. S., R. A. Dalloul, and W. Min. Enhancing intestinal immunity to coccidiosis. World Poult. 19 (Coccidiosis Special):18-21. 2003.
20. Lillehoj, H. S., and E. P. Lillehoj. Avian coccidiosis. A review of acquired intestinal immunity and vaccination strategies. Avian Dis. 44:408-425. 2000.
21. Lillehoj, H. S., and M. D. Ruff. Comparison of disease susceptibility and subclass-specific antibody response in SC and FP chickens experimentally inoculated with Eimeria tenella, E. acervulina, or E. maxima. Avian Dis. 31:112-119. 1987.
22. Mena, A., A. K. Nichani, Y. Popowych, D. L. Godson, D. Dent, H. G. G. Townsend, G. K. Mutwiri, R. Hecker, L. A. Babiuk, and P. Griebel. Innate immune responses induced by CpG oligodeoxyribonucleotide stimulation of ovine blood mononuclear cells. Immunology 110:250-257. 2003.
23. Mutwiri, G., R. Pontarollo, S. Babiuk, P. Griebel, S. van Drunen Littel-van den Hurk, A. Mena, C. Tsang, V. Alcon, A. Nichani, and X. Ioannou. Biological activity of immunostimulatory CpG DNA motifs in domestic animals. Vet. Immunol. Immunopathol. 91:89-103. 2003.
24. Rankin, R., R. Pontarollo, X. Ioannou, A. M. Krieg, R. Hecker, L. A. Babiuk, S. van Drunen and Littel-van den Hurk. CpG motif identification for veterinary and laboratory species demonstrates that sequence recognition is highly conserved. Antisense Nucleic Acid Drug Dev. 11:333-340. 2001.
25. Su, Z., M. F. Tam, D. Jankovic, and M. M. Stevenson. Vaccination with novel immunostimulatory adjuvants against blood-stage malaria in mice. Infect. Immun. 71:5178-5187. 2003.
26. Verthelyi, D., M. Gursel, R. T. Kenney, J. D. Lifson, S. Liu, J. Mican, and D. M. Klinman. CpG oligodeoxynucleotides protect normal and SIV-infected macaques from Leishmania infection. J. Immunol. 170:4717-4723. 2003.
27. Vleugels, B., C. Ververken, and B. M. Goddeeris. Stimulatory effect of CpG sequences on humoral response in chickens. Poult. Sci. 81:1317-1321. 2002.
28. Walker, P. S., T. Scharton-Kersten, A. M. Krieg, L. Love-Homan, E. D. Rowton, M. C. Udey, and J. C. Vogel. Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12- and IFN-gamma-dependent mechanisms. Proc. Natl. Acad. Sci. USA 96:6970-6975. 1999.
29. Wernette, C. M., B. F. Smith, Z. L. Barksdale, R. Hecker, and H. J. Baker. CpG oligodeoxynucleotides stimulate canine and feline immune cell proliferation. Vet. Immunol. Immunopathol. 84:223-236. 2002.
30. Xie, H., R. B. Raybourne, U. S. Babu, H. S. Lillehoj, and R. A. Heckert. CpG-induced immunomodulation and intracellular bacterial killing in a chicken macrophage cell line. Dev. Comp. Immunol. 27:823-834. 2003.
31. Yun, C. H., H. S. Lillehoj, and K. D. Choi. Eimeria tenella infection induces local gamma interferon production and intestinal lymphocyte subpopulation changes. Infect. Immun. 68:1282-1288. 2000.
32. Zhang, Y., L. K. Shoda, K. A. Brayton, D. M. Estes, G. H. Palmer, and W. C. Brown. Induction of interleukin-6 and interleukin-12 in bovine B lymphocytes, monocytes, and macrophages by a CpG oligodeoxynucleotide (ODN 2059) containing the GTCGTT motif. J. Interf. Cytok. Res. 21:871-881. 2001.
33. Zimmermann, S., O. Egeter, S. Hausmann, G. B. Lipford, M. Rocken, H. Wagner, and K. Heeg. CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis. J. Immunol. 160:3627-3630. 1998.