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Volumn 271, Issue 7, 2004, Pages 1339-1347

Induction of endothelial apoptosis by 4-hydroxyhexenal

Author keywords

4 Hydroxyhexenal; Apoptosis; Oxidative stress; Peroxynitrite; Vascular dysfunction

Indexed keywords

4 HYDROXYHEXENAL; 4 HYDROXYNONENAL; ACETYLCYSTEINE; ALDEHYDE DERIVATIVE; PENICILLAMINE; PEROXYNITRITE; UNCLASSIFIED DRUG;

EID: 11144358265     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.2004.04042.x     Document Type: Article
Times cited : (46)

References (49)
  • 1
    • 0027265381 scopus 로고
    • Free radicals in brain metabolism and pathology
    • Evans, P. (1993) Free radicals in brain metabolism and pathology. Br. Med. Bull. 49, 577-587.
    • (1993) Br. Med. Bull. , vol.49 , pp. 577-587
    • Evans, P.1
  • 2
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynenenal, malonaldehyde and related aldehydes
    • Esterbauer, H., Schaur, R.J. & Zollner, H. (1991) Chemistry and biochemistry of 4-hydroxynenenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 11, 81-128.
    • (1991) Free Radic. Biol. Med. , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 3
    • 0029866196 scopus 로고    scopus 로고
    • 4-Hydroxyhexenal is a potent inducer of the mitochondrial permeability transition
    • Kristal, B.S., Park, B.K. & Yu, B.P. (1996) 4-Hydroxyhexenal is a potent inducer of the mitochondrial permeability transition. J. Biol. Chem. 271, 6033-6038.
    • (1996) J. Biol. Chem. , vol.271 , pp. 6033-6038
    • Kristal, B.S.1    Park, B.K.2    Yu, B.P.3
  • 5
    • 0035871770 scopus 로고    scopus 로고
    • Apoptosis in RAW 264.7 cells exposed to 4-hydroxy-2-nonenal: Dependence on cytochrome c release but not p53 accumulation
    • Haynes, R.L., Brune, B. & Townsend, A.J. (2001) Apoptosis in RAW 264.7 cells exposed to 4-hydroxy-2-nonenal: dependence on cytochrome c release but not p53 accumulation. Free Radic. Biol. Med. 30, 884-894.
    • (2001) Free Radic. Biol. Med. , vol.30 , pp. 884-894
    • Haynes, R.L.1    Brune, B.2    Townsend, A.J.3
  • 6
    • 0035426001 scopus 로고    scopus 로고
    • Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60 cells
    • Anuradha, C.D., Kanno, S. & Hirano, S. (2001) Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60 cells. Free Radic. Biol. Med. 31, 367-373.
    • (2001) Free Radic. Biol. Med. , vol.31 , pp. 367-373
    • Anuradha, C.D.1    Kanno, S.2    Hirano, S.3
  • 7
    • 0031020476 scopus 로고    scopus 로고
    • A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide
    • Mark, R.J., Lovell, M.A., Markesbery, W.R., Uchida, K. & Mattson, M.P. (1997) A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide. J. Neurochem. 68, 255-264.
    • (1997) J. Neurochem. , vol.68 , pp. 255-264
    • Mark, R.J.1    Lovell, M.A.2    Markesbery, W.R.3    Uchida, K.4    Mattson, M.P.5
  • 9
    • 0035881921 scopus 로고    scopus 로고
    • Transfection of mGSTA4 in HL-60 cells protects against 4-hydroxynonenal-induced apoptosis by inhibiting JNK-mediated signaling
    • Cheng, J.Z., Singhal, S.S., Sharma, A., Saini, M., Yang, Y., Awasthi, S., Zimniak, P. & Awasthi, Y.C. (2001) Transfection of mGSTA4 in HL-60 cells protects against 4-hydroxynonenal-induced apoptosis by inhibiting JNK-mediated signaling. Arch. Biochem. Biophys. 392, 197-207.
    • (2001) Arch. Biochem. Biophys. , vol.392 , pp. 197-207
    • Cheng, J.Z.1    Singhal, S.S.2    Sharma, A.3    Saini, M.4    Yang, Y.5    Awasthi, S.6    Zimniak, P.7    Awasthi, Y.C.8
  • 11
    • 0035969890 scopus 로고    scopus 로고
    • Apoptosis of PC12 cells by 4-hydroxy-2-nonenal is mediated through selective activation of the c-Jun N-terminal protein kinase pathway
    • Song, B.J., Soh, Y., Bae, M., Pie, J., Wan, J. & Jeong, K. (2001) Apoptosis of PC12 cells by 4-hydroxy-2-nonenal is mediated through selective activation of the c-Jun N-terminal protein kinase pathway. Chem, Biol. Interact. 130-132, 943-954.
    • (2001) Chem, Biol. Interact. , vol.130-132 , pp. 943-954
    • Song, B.J.1    Soh, Y.2    Bae, M.3    Pie, J.4    Wan, J.5    Jeong, K.6
  • 13
    • 0035072605 scopus 로고    scopus 로고
    • 4-Hydroxynonenal induces apoptosis, NF-kappa B-activation and formation of 8-isoprostane in vascular smooth muscle cells
    • Ruef, J., Moser, M., Bode, C., Kubler, W. & Runge, M.S. (2001) 4-Hydroxynonenal induces apoptosis, NF-kappa B-activation and formation of 8-isoprostane in vascular smooth muscle cells. Basic Res. Cardiol. 96, 143-150.
    • (2001) Basic Res. Cardiol. , vol.96 , pp. 143-150
    • Ruef, J.1    Moser, M.2    Bode, C.3    Kubler, W.4    Runge, M.S.5
  • 14
    • 0033597234 scopus 로고    scopus 로고
    • 4-Hydroxynonenal prevents NF-kappa B activation and tumor necrosis factor expression by inhibiting IkappaB phosphorylation and subsequent proteolysis
    • Page, S., Fischer, C., Baumgartner, B., Haas, M., Kreusel, U., Loidl, G., Hayn, M., Ziegler-Heitbrock, H.W., Neumeier, D. & Brand, K. (1999) 4-Hydroxynonenal prevents NF-kappa B activation and tumor necrosis factor expression by inhibiting IkappaB phosphorylation and subsequent proteolysis. J. Biol. Chem. 274, 11611-11618.
    • (1999) J. Biol. Chem. , vol.274 , pp. 11611-11618
    • Page, S.1    Fischer, C.2    Baumgartner, B.3    Haas, M.4    Kreusel, U.5    Loidl, G.6    Hayn, M.7    Ziegler-Heitbrock, H.W.8    Neumeier, D.9    Brand, K.10
  • 15
    • 0034727901 scopus 로고    scopus 로고
    • The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of nuclear factor kB in neurons
    • Camandola, S., Poli, G. & Mattson, N.P. (2000) The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of nuclear factor kB in neurons. Mol. Brain Res. 85, 53-60.
    • (2000) Mol. Brain Res. , vol.85 , pp. 53-60
    • Camandola, S.1    Poli, G.2    Mattson, N.P.3
  • 19
    • 0036937872 scopus 로고    scopus 로고
    • Prevention of free-radical induced apoptosis by induction of human recombinant Cu, Zn-SOD in pig endothelial cells
    • Yokoyama, I., Negita, M., Liu, D.G., Nagasaka, T., Kobayashi, T., Hayakawa, A., Hayashi, S. & Nakao, A. (2002) Prevention of free-radical induced apoptosis by induction of human recombinant Cu, Zn-SOD in pig endothelial cells. Transpl. Int. 15, 220-225.
    • (2002) Transpl. Int. , vol.15 , pp. 220-225
    • Yokoyama, I.1    Negita, M.2    Liu, D.G.3    Nagasaka, T.4    Kobayashi, T.5    Hayakawa, A.6    Hayashi, S.7    Nakao, A.8
  • 22
    • 0030737530 scopus 로고    scopus 로고
    • The physiology and pathophysiology of the nitric oxide/superoxide system
    • Munzel, T., Heitzer, T. & Harrison, D.G. (1997) The physiology and pathophysiology of the nitric oxide/superoxide system. Herz 22, 158-172.
    • (1997) Herz , vol.22 , pp. 158-172
    • Munzel, T.1    Heitzer, T.2    Harrison, D.G.3
  • 23
    • 0021027358 scopus 로고
    • Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein fluorescent assay
    • Cathcar, T.R., Schwiers, E. & Ames, B.N. (1983) Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein fluorescent assay. Anal. Biochem. 134, 111-116.
    • (1983) Anal. Biochem. , vol.134 , pp. 111-116
    • Cathcar, T.R.1    Schwiers, E.2    Ames, B.N.3
  • 25
    • 0032929619 scopus 로고    scopus 로고
    • Inhibitory effects of catecholamines and anti-oxidants on the fluorescence reaction of 4,5-diaminofluorescein, DAF-2, a novel indicator of nitric oxide
    • Nagata, N., Momose, K. & Ishida, Y. (1999) Inhibitory effects of catecholamines and anti-oxidants on the fluorescence reaction of 4,5-diaminofluorescein, DAF-2, a novel indicator of nitric oxide. J. Biochem. Tokyo 125, 658-661.
    • (1999) J. Biochem. Tokyo , vol.125 , pp. 658-661
    • Nagata, N.1    Momose, K.2    Ishida, Y.3
  • 26
    • 0032803509 scopus 로고    scopus 로고
    • Superoxide dismutase and hydrogen peroxide cause rapid nitric oxide breakdown, peroxynitrite production and subsequent cell death
    • McBride, A.G., Borutaite, V. & Brown, G.C. (1999) Superoxide dismutase and hydrogen peroxide cause rapid nitric oxide breakdown, peroxynitrite production and subsequent cell death. Biochim. Biophys. Acta 1454, 275-288.
    • (1999) Biochim. Biophys. Acta , vol.1454 , pp. 275-288
    • McBride, A.G.1    Borutaite, V.2    Brown, G.C.3
  • 27
    • 0028939862 scopus 로고
    • The genetic regulation of apoptosis
    • Wyllie, A.H. (1995) The genetic regulation of apoptosis. Curr. Opin. Genet. Dev. 5, 97-104.
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 97-104
    • Wyllie, A.H.1
  • 28
    • 0029037495 scopus 로고
    • The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide
    • Pryor, W.A. & Squadrito, G.L. (1995) The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide. Am. J. Physiol. 268, L699-L722.
    • (1995) Am. J. Physiol. , vol.268
    • Pryor, W.A.1    Squadrito, G.L.2
  • 29
    • 0029759443 scopus 로고    scopus 로고
    • Aging and oxidative stress: Modulation by dietary restriction
    • Yu, B.P. (1996) Aging and oxidative stress: modulation by dietary restriction. Free Radic. Biol. Med. 21, 651-668.
    • (1996) Free Radic. Biol. Med. , vol.21 , pp. 651-668
    • Yu, B.P.1
  • 30
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross, R. (1993) The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362, 801-809.
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 31
    • 0029113373 scopus 로고
    • Evidence for apoptosis in human atherogenesis and in a rat vascular injury model
    • Han, D.K., Haudenschild, C.C., Hong, M.K., Tinkle, B.T., Leon, M.B. & Liau, G. (1995) Evidence for apoptosis in human atherogenesis and in a rat vascular injury model. Am. J. Pathol. 147, 267-277.
    • (1995) Am. J. Pathol. , vol.147 , pp. 267-277
    • Han, D.K.1    Haudenschild, C.C.2    Hong, M.K.3    Tinkle, B.T.4    Leon, M.B.5    Liau, G.6
  • 33
    • 0042882640 scopus 로고    scopus 로고
    • Lipid peroxidation and cell cycle signaling: 4-Hydroxynonenal, a key molecule in stress mediated signaling
    • Yang, Y., Sharma, R., Sharma, A., Awasthi, S. & Awasthi, Y.C. (2003) Lipid peroxidation and cell cycle signaling: 4-hydroxynonenal, a key molecule in stress mediated signaling. Acta Biochim. Pol. 50, 319-336.
    • (2003) Acta Biochim. Pol. , vol.50 , pp. 319-336
    • Yang, Y.1    Sharma, R.2    Sharma, A.3    Awasthi, S.4    Awasthi, Y.C.5
  • 34
    • 0033593225 scopus 로고    scopus 로고
    • Activation of stress signaling pathways by the end product of lipid peroxidation. 4-Hydroxy-2-nonenal is a potential inducer of intracellular peroxide production
    • Uchida, K., Shiraishi, M., Naito, Y., Torii, Y., Nakamura, Y. & Osawa, T. (1999) Activation of stress signaling pathways by the end product of lipid peroxidation. 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production. J. Biol. Chem. 274, 2234-2242.
    • (1999) J. Biol. Chem. , vol.274 , pp. 2234-2242
    • Uchida, K.1    Shiraishi, M.2    Naito, Y.3    Torii, Y.4    Nakamura, Y.5    Osawa, T.6
  • 35
    • 0027519515 scopus 로고
    • Immunostaining of human autopsy aortas with antibodies to modified apolipoprotein B and apoprotein (a)
    • Jurgens, G., Chen, Q., Esterbauer, H., Mair, S., Ledinski, G. & Dinges, H.P. (1993) Immunostaining of human autopsy aortas with antibodies to modified apolipoprotein B and apoprotein (a). Arterioscler. Thromb. 13, 1689-1699.
    • (1993) Arterioscler. Thromb. , vol.13 , pp. 1689-1699
    • Jurgens, G.1    Chen, Q.2    Esterbauer, H.3    Mair, S.4    Ledinski, G.5    Dinges, H.P.6
  • 36
    • 0032853335 scopus 로고    scopus 로고
    • 4-Hydroxynonenal induces dysfunction and apoptosis of cultured endothelial cells
    • Herbst, U., Toborek, M., Kaiser, S., Mattson, M.P. & Hennig, B. (1999) 4-Hydroxynonenal induces dysfunction and apoptosis of cultured endothelial cells. J. Cell. Physiol. 181, 295-303.
    • (1999) J. Cell. Physiol. , vol.181 , pp. 295-303
    • Herbst, U.1    Toborek, M.2    Kaiser, S.3    Mattson, M.P.4    Hennig, B.5
  • 37
    • 0035967824 scopus 로고    scopus 로고
    • Vascular smooth muscle cell activation and growth by 4-hydroxynonenal
    • Kakishita, H. & Hattori, Y. (2001) Vascular smooth muscle cell activation and growth by 4-hydroxynonenal. Life Sci. 69, 689-697.
    • (2001) Life Sci. , vol.69 , pp. 689-697
    • Kakishita, H.1    Hattori, Y.2
  • 39
    • 0033945846 scopus 로고    scopus 로고
    • Mitochondrial oxidative stress plays a key role in aging and apoptosis
    • Sastre, J., Pallardo, F.V. & Vina, J. (2000) Mitochondrial oxidative stress plays a key role in aging and apoptosis. IUBMB Life. 49, 427-435.
    • (2000) IUBMB Life , vol.49 , pp. 427-435
    • Sastre, J.1    Pallardo, F.V.2    Vina, J.3
  • 40
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homologue bax that accelerates programmed cell death
    • Oltvai, Z.N., Milliman, C.L. & Korsmeye, R.S.J. (1993) Bcl-2 heterodimerizes in vivo with a conserved homologue bax that accelerates programmed cell death. Cell 74, 609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeye, R.S.J.3
  • 41
    • 0028857248 scopus 로고
    • Detection of 4-hydroxynonenal (HNE) as a physiological component in human plasma
    • Strohmaier, H., Hinghofer-Szalkay, H. & Schaur, R.J. (1995) Detection of 4-hydroxynonenal (HNE) as a physiological component in human plasma. J. Lipid Med. Cell. Signal 11, 51-61.
    • (1995) J. Lipid Med. Cell. Signal , vol.11 , pp. 51-61
    • Strohmaier, H.1    Hinghofer-Szalkay, H.2    Schaur, R.J.3
  • 42
    • 0028223268 scopus 로고
    • Formation of 4-hydroxy-2-nonenal-modified proteins in the renal proximal tubules of rats treated with a renal carcinogen, ferric nitrilotriacetate
    • Toyokuni, S., Uchida, K., Okamoto, K., Hattori-Nakakuki, Y., Hia, i, H. & Stadtman, E.R. (1994) Formation of 4-hydroxy-2-nonenal-modified proteins in the renal proximal tubules of rats treated with a renal carcinogen, ferric nitrilotriacetate. Proc. Natl Acad. Sci. USA 91, 2616-2620.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2616-2620
    • Toyokuni, S.1    Uchida, K.2    Okamoto, K.3    Hattori-Nakakuki, Y.4    Hia, I.H.5    Stadtman, E.R.6
  • 43
    • 0034077078 scopus 로고    scopus 로고
    • 4-Hydroxynonenal induces oxidative stress and death of cultured spinal cord neurons
    • Malecki, A., Garrido, R., Mattson, M.P., Hennig, B. & Toborek, M. (2000) 4-Hydroxynonenal induces oxidative stress and death of cultured spinal cord neurons. J. Neurochem. 74, 2278-2287.
    • (2000) J. Neurochem. , vol.74 , pp. 2278-2287
    • Malecki, A.1    Garrido, R.2    Mattson, M.P.3    Hennig, B.4    Toborek, M.5
  • 44
    • 0041669519 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal as a COX-2 inducer
    • Uchida, K. & Kumagai, T. (2003) 4-Hydroxy-2-nonenal as a COX-2 inducer. Mol. Aspects Med. 24, 213-218.
    • (2003) Mol. Aspects Med. , vol.24 , pp. 213-218
    • Uchida, K.1    Kumagai, T.2
  • 45
    • 0029760021 scopus 로고    scopus 로고
    • Formation of nitrating and chlorinating species by reaction of nitrite with hypochlorous acid. A novel mechanism for nitric oxide-mediated protein modification
    • Eiserich, J.P., Cross, C.E., Jones, A.D., Halliwel, I, B. & van der Vliet, A. (1996) Formation of nitrating and chlorinating species by reaction of nitrite with hypochlorous acid. A novel mechanism for nitric oxide-mediated protein modification. J. Biol. Chem. 271, 19199-19208.
    • (1996) J. Biol. Chem. , vol.271 , pp. 19199-19208
    • Eiserich, J.P.1    Cross, C.E.2    Jones, A.D.3    Halliwel, I.B.4    Van Der Vliet, A.5
  • 46
    • 0027930057 scopus 로고
    • Evidence for nitric oxide-mediated oxidative damage in chronic inflammation nitrotyrosine in serum and synovial fluid from rheumatoid patients
    • Kaur, H. & Halliwell, B. (1994) Evidence for nitric oxide-mediated oxidative damage in chronic inflammation nitrotyrosine in serum and synovial fluid from rheumatoid patients. FEBS Lett. 350, 9-12.
    • (1994) FEBS Lett. , vol.350 , pp. 9-12
    • Kaur, H.1    Halliwell, B.2
  • 47
    • 0034102203 scopus 로고    scopus 로고
    • The effect of age on cyclooxygenase-2 gene expression: NF-kappa B activation and IkappaBalpha degradation
    • Kim, H.J. & Kim, K.W., Yu, B.P. & Chung, H.Y. (2000) The effect of age on cyclooxygenase-2 gene expression: NF-kappa B activation and IkappaBalpha degradation. Free Radic. Biol. Med. 28, 683-692.
    • (2000) Free Radic. Biol. Med. , vol.28 , pp. 683-692
    • Kim, H.J.1    Kim, K.W.2    Yu, B.P.3    Chung, H.Y.4
  • 48
    • 0035040549 scopus 로고    scopus 로고
    • The inflammation hypothesis of aging: Molecular modulation by calorie restriction
    • Chung, H.Y., Kim, H.J., Kim, J.W. & Yu B.P. (2001) The inflammation hypothesis of aging: molecular modulation by calorie restriction. Ann. NY Acad. Sci. 928, 327-335.
    • (2001) Ann. NY Acad. Sci. , vol.928 , pp. 327-335
    • Chung, H.Y.1    Kim, H.J.2    Kim, J.W.3    Yu, B.P.4


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