4-Hydroxynonenal induces apoptosis, NF-κB-activation and formation of 8-isoprostane in vascular smooth muscle cells

Basic Research in Cardiology

Volumn 96, Issue 2, 2001, Pages 143-150

  Ruef, Johannes ^a   Moser, Martin ^a   Bode, Christoph ^b   Kübler, Wolfgang ^a   Runge, Marschall S ^c  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

4 hydroxynonenal; Apoptosis; Atherosclerosis; Lipid peroxidation; Oxidant signaling

Indexed keywords

4 HYDROXYNONENAL; ACETYLCYSTEINE; ANTIOXIDANT; DNA; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOPROSTANE DERIVATIVE; LIPID PEROXIDE; MALONALDEHYDE; OXIDIZED LOW DENSITY LIPOPROTEIN; PYRROLIDINE DITHIOCARBAMATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CELL GROWTH; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; MITOGENESIS; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN DNA BINDING; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ALDEHYDES; ANIMALS; AORTA; APOLIPOPROTEINS E; APOPTOSIS; CELLS, CULTURED; CORONARY ARTERIOSCLEROSIS; CULTURE MEDIA, CONDITIONED; CYSTEINE PROTEINASE INHIBITORS; DINOPROST; DNA; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; F2-ISOPROSTANES; HUMANS; I-KAPPA B PROTEINS; LIPID PEROXIDATION; LIPID PEROXIDES; MICE; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; NF-KAPPA B; OXIDATIVE STRESS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 0035072605     PISSN: 03008428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003950170064     Document Type: Article

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