Liver-derived IGF-I regulates GH secretion at the pituitary level in mice

Endocrinology

Volumn 142, Issue 11, 2001, Pages 4762-4770

  Wallenius, Kristina ^a   Sjögren, Klara ^a   Peng, Xiao Ding ^b   Park, Seungjoon ^b   Wallenius, Ville ^a   Liu, Jun Li ^c   Umaerus, Mia ^d   Wennbo, Håkan ^d   Isaksson, Olle ^a   Frohman, Lawrence ^b   Kineman, Rhonda ^b   Ohlsson, Claes ^a   Jansson, John Olov ^a,e  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c MCGILL UNIVERSITY   (Canada)

^d ASTRAZENECA R AND D   (Sweden)

^e Research Center for Endocrinology and Metabolism   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR RECEPTOR; MESSENGER RNA; NEUROPEPTIDE Y; PROLACTIN RECEPTOR; SOMATOMEDIN C; SOMATOSTATIN; SOMATOSTATIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE DELETION; GROWTH HORMONE RELEASE; HYPOPHYSIS; HYPOTHALAMUS HYPOPHYSIS SYSTEM; LIVER; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 17944377821     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.142.11.8478     Document Type: Article

References (46)

1. Sexual dimorphism in the control of growth hormone secretion
2. Age- and sex-related differences in episodic growth hormone secretion in the rat
3. Patterns of growth hormone-releasing factor and somatostatin secretion into the hypophysial-portal circulation of the rat
4. The interrelationship of growth hormone (GH)-releasing factor and somatostatin in generation of the ultradian rhythm of GH secretion
5. Regulatory mechanisms of growth hormone secretion are sexually dimorphic
6. Human growth hormone and somatomedin C suppress the spontaneous release of growth hormone in unanesthetized rats
7. Insulin-like growth factors: A role in growth hormone negative feedback and body weight regulation via brain
8. Synergistic interaction between insulin-like growth factors-I and -II in central regulation of pulsatile growth hormone secretion
9. Somatomedin-C mediates growth hormone negative feedback by effects on both the hypothalamus and the pituitary
10. Insulin-like growth factor I action on rat anterior pituitary cells: Suppression of growth hormone secretion and messenger ribonucleic acid levels
11. Hypothalamic/pituitary-axis of the spontaneous dwarf rat: Autofeedback regulation of growth hormone (GH) includes suppression of GH releasing- hormone receptor messenger ribonucleic acid
12. Differential effects of central and peripheral administration of growth hormone (GH) and insulin-like growth factor on hypothalamic GH-releasing hormone and somatostatin gene expression in GH-deficient dwarf rats
13. Hormonal regulation of rat hypothalamic neuropeptide mRNAs: Effect of hypophysectomy and hormone replacement on growth-hormone-releasing factor, somatostatin and the insulin-like growth factors
14. Peptidomimetic regulation of growth hormone secretion
15. Ghrelin is a growth-hormone-releasing acylated peptide from stomach Nature
16. On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone
17. Growth hormone (GH) secretagogues and neuroendocrine regulation of GH secretion
18. Secretory rhythm of growth hormone regulates sexual differentiation of mouse liver
19. Gigantism in mice lacking suppressor of cytokine signalling-2
20. Regulation of sexually dimorphic hepatic steroid metabolism by the somatostatin-growth hormone axis
21. Interpulse interval in circulating growth hormone patterns regulates sexually dimorphic expression of hepatic cytochrome P450
22. Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice
23. Normal growth and development in the absence of hepatic insulin-like growth factor I
24. Radioimmunoassays for IGFs and IGFBPs
25. A secreted fluorescent reporter targeted to pituitary growth hormone cells in transgenic mice
26. The growth hormone (GH)-axis of GH receptor/binding protein gene-disrupted and metallothionein-human GH-releasing hormone transgenic mice: Hypothalamic neuropeptide and pituitary receptor expression in the absence and presence of GH feedback
27. Prolactin (PRL) receptor gene expression in mouse adipose tissue: Increases during lactation and in PRL-transgenic mice
28. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
29. Ipamorelin, the first selective growth hormone secretagogue
30. Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene
31. Effects of recombinant human insulin-like growth factor I (IGF-I) therapy on the growth hormone-IGF system of a patient with a partial IGF-I gene deletion
32. A low dose euglycemic infusion of recombinant human insulin-like growth factor I rapidly suppresses fasting-enhanced pulsatile growth hormone secretion in humans
33. Leptin regulates pulsatile luteinizing hormone and growth hormone secretion in the sheep
34. Liver-derived IGF-I is of importance for normal carbohydrate and lipid metabolism
35. Liver-specific IGF-1 gene deletion leads to muscle insulin insensitivity
36. Growth hormone-releasing hormone
37. A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)
38. Effect of insulin-like growth factor-I on growth hormone-releasing factor receptor expression in primary rat anterior pituitary cell culture
39. Growth hormone-dependent regulation of pituitary GH secretagogue receptor (GHS-R) mRNA levels in the spontaneous dwarf Rat
40. Role of NPY neurons in GH-dependent feedback signalling to the brain
41. Growth hormone inhibits its own secretion by acting on the hypothalamus through its receptors on neuropeptide Y neurons in the arcuate nucleus and somatostatin neurons in the periventricular nucleus
42. Growth hormone dependence of somatomedin-C/insulin-like growth factor-I and insulin-like growth factor-II messenger ribonucleic acids
43. Effects of recombinant human insulin-like growth factor I administration on growth hormone (GH) secretion, both spontaneous and stimulated by GH-releasing hormone or hexarelin, a peptidyl GH secretagogue, in humans
44. Evidence for an endogenous ultradian rhythm governing growth hormone secretion in the rat
45. Histopathology associated with elevated levels of growth hormone and insulin-like growth factor I in transgenic mice
46. Disproportional skeletal growth and markedly decreased bone mineral content in growth hormone receptor -/- mice