Spinal disposition and meningeal permeability of local anesthetics

Pharmaceutical Research

Volumn 21, Issue 4, 2004, Pages 706-716

  Clément, Rozenn ^a   Malinovsky, Jean Marc ^a   Hildgen, Patrice ^b   Dollo, Gilles ^a   Estèbe, Jean Pierre ^a   Chevanne, François ^a   Le Verge, Roger ^a   Le Corre, Pascal ^a  

^a UNIVERSITÉ DE RENNES 1   (France)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Cerebrospinal fluid bioavailability; ex vivo spinal meningeal permeability; Intrathecal and epidural disposition; Local anesthetics; Microdialysis

Indexed keywords

BUPIVACAINE; LOCAL ANESTHETIC AGENT; MEPIVACAINE; ROPIVACAINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CEREBROSPINAL FLUID; CERVICAL SPINE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG PENETRATION; DURA MATER; EPIDURAL SPACE; FEMALE; LIPOPHILICITY; LUMBAR SPINE; MENINX; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RABBIT; SPINAL ARACHNOID; SPINE;

ANESTHETICS, LOCAL; ANIMALS; FEMALE; MENINGES; PERMEABILITY; RABBITS; SPINAL CORD;

EID: 11144354445     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:PHAM.0000022419.18144.9e     Document Type: Article

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