Application of microdialysis to characterize drug disposition in tumors

Advanced Drug Delivery Reviews

Volumn 45, Issue 2-3, 2000, Pages 243-253

  Chu, Jianxiong ^a   Gallo, James M ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

Concentration time profile; Drug disposition; In vivo sampling; Microdialysis; Pharmacokinetic; Tumors

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; CISPLATIN; COLLAGEN; CYCLOSPORIN A; CYTOTOXIC AGENT; DOXORUBICIN; ETOPOSIDE; FLUOROURACIL; LIPOSOME; METHOTREXATE; TIRAPAZAMINE; TOPOTECAN;

ANGIOGENESIS; CALIBRATION; CANCER CHEMOTHERAPY; DRUG DELIVERY SYSTEM; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG TISSUE LEVEL; DRUG TUMOR LEVEL; HUMAN; IN VIVO STUDY; INSTRUMENTATION; INTERSTITIAL FLUID; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; SAMPLING; SOLID TUMOR;

BLOOD; CONTROLLED DRUG DELIVERY; DRUG INFUSION; METABOLISM; PHARMACOKINETICS; TISSUE;

DRUG DISPOSITION; MICRODIALYSIS;

DIALYSIS;

EID: 0034672440     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(00)00115-0     Document Type: Article

References (56)

1. Delivery of novel therapeutic agents in tumors: Physiological barriers and strategies
2. Vascular and interstitial barriers to delivery of therapeutic agents in tumors
3. Concentration of phenoxymethylpenicillin in tonsillar tissue
4. Tumor-tissue and plasma concentrations of platinum during chemotherapy of non-small-cell lung cancer patients
5. Antiangiogenic treatment (TNP-470/minocycline) increases tissue levels of anticancer drugs in mice bearing Lewis lung carcinoma
6. 14C]methotrexate after intracarotid administration without and with hyperosmotic opening of the blood-brain and blood-tumor barriers in rat brain tumors: A quantitative autoradiographic study
7. Association of intratumoral pharmacokinetics of fluorouracil with clinical response
8. In vivo tissue pharmacokinetics by fluorine magnetic resonance spectroscopy: A study of liver and muscle disposition of fleroxacin in humans
9. The concentrations of free amino acids and other electrolytes in cerebrospinal fluid, in vivo dialysate of brain, and blood plasma of the dog
10. Brain microdialysis and its application for the study of animal behaviour
11. Microdialysis in the Neurosciences
12. Application of microdialysis in pharmacokinetic studies
13. Pharmacokinetic and metabolism studies using microdialysis sampling
14. In vivo microdialysis sampling: Theory and applications
15. Quantitative assessment of blood-brain barrier damage during microdialysis
16. Examination of microdialysis sampling in a well-characterized hydrodynamic system
17. Intracerebral microdialysis: II. Mathematical studies of diffusion kinetics
18. Intracerebral microdialysis: I. Experimental studies of diffusion kinetics
19. Microdialysis: Theory and application
20. Steady-state theory for quantitative microdialysis of solutes and water in vivo and in vitro
21. Quantitative microdialysis: Analysis of transients and application to pharmacokinetics in brain
22. Effects of different semipermeable membranes on in vitro and in vivo performance of microdialysis probes
23. A comparison between three methods for estimation of extracellular concentrations of exogenous and endogenous compounds by microdialysis
24. Drug distribution studies with microdialysis: I. Tissue dependent difference in recovery between caffeine and theophylline
25. In vivo calibration of microdialysis probes for exogenous compounds
26. Protein binding of indomethacin, methotrexate and morphine in patients with cancer
27. In vivo microdialysis to characterize drug transport in brain tumors: Analysis of methotrexate uptake in rat glioma-2 (RG-2)-bearing rats
28. Pharmacokinetic-pharmacodynamic modeling of the antibiotic effect of piperacillin in vitro
29. Determination of free extracellular levels of methotrexate by microdialysis in muscle and solid tumor of the rabbit
30. Relationship between tumor extracellular fluid exposure to topotecan and tumor response in human neuroblastoma xenograft and cell lines
31. Mass transfer in brain dialysis devices: A new method for the estimation of extracellular amino acids concentration
32. A microdialysis method allowing characterization of intercellular water space in humans
33. The use of an 'internal standard' for control of the recovery in microdialysis
34. Antipyrine as a dialyzable reference to correct differences in efficiency among and within sampling devices during in vivo microdialysis
35. Analysis of zidovudine distribution to specific regions in rabbit brain using microdialysis
36. Microdialysis calibration using retrodialysis and zero-net flux: Application to a study of the distribution of zidovudine to rabbit cerebrospinal fluid and thalamus
37. In vitro and in vivo microdialysis calibration for the measurement of carbamazepine and its metabolites in rat brain tissue using the internal reference technique
38. Microdialysis probes calibration: Gradient and tissue dependent changes in no net flux and reverse dialysis methods
39. Drug distribution studies with microdialysis: III. Extracellular concentration of caffeine in adipose tissue in man
40. A survey on quantitative microdialysis: Theoretical models and practical implications
41. Methodological considerations of intracerebral microdialysis in pharmacokinetic studies on drug transport across the blood-brain barrier
42. Microdialysis sampling in tumor and muscle: Study of the disposition of 3-amino-1,2,4-benzotriazine-1,4-di-N-oxide (SR 4233)
43. Intratumoral differences in methotrexate levels within human osteosarcoma xenografts studied by microdialysis
44. The use of intracerebral microdialysis for the determination of pharmacokinetic profiles of anticancer drugs in tumor-bearing rat brain
45. In-vivo microdialysis study of the distribution of cisplatin into brain tumour tissue after intracarotid infusion in rats with 9L malignant glioma
46. Uptake of drugs and expression of P-glycoprotein in the rat 9L glioma
47. Microdialysis assessment of microfibrous collagen containing a P-glycoprotein-mediated transport inhibitor, cyclosporine A, for local delivery of etoposide
48. Microdialysis assessment of fibrin glue containing sodium alginate for local delivery of doxorubicin in tumor-bearing rats
49. Microdialysis assessment of 5-fluorouracil release from thermosensitive magnetoliposomes induced by an electromagnetic field in tumor-bearing mice
50. Uptake of temozolomide in a rat glioma model in the presence and absence of the angiogenesis inhibitor TNP-470
51. Application of microdialysis to clinical pharmacokinetics in humans
52. Measurement of extracellular fluid carboplatin kinetics in melanoma metastases with microdialysis
53. 5-Fluorouracil kinetics in the interstitial tumor space: Clinical response in breast cancer patients
54. Analysis of microdialysates from cancer patients by capillary electrophoresis
55. Interstitial methotrexate kinetics in primary breast cancer lesions
56. Continuous intratumoral microdialysis during high-dose methotrexate therapy in a patient with malignant fibrous histiocytoma of the femur: A case report