The neuroprotective effect of the antioxidant flavonoid derivate di-tert-butylhydroxyphenyl is parallel to the preventive effect on post-ischemic Kir2.x impairment but not to post-ischemic endothelial dysfunction

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 370, Issue 5, 2004, Pages 395-403

  Pétrault, Olivier ^a   Bastide, Michèle ^a   Cotelle, Nicole ^a   Gelé, Patrick ^a   Gautier, Sophie ^a   Laprais, Maud ^a   Vamecq, Joseph ^a   Duriez, Patrick ^b   Bordet, Régis ^a  

^a UNIV LILLE   (France)

^b INSERM   (France)

Author keywords

Endothelium; Flavonoids; Ischemia reperfusion; Oxidative stress; Potassium channel; Smooth muscle

Indexed keywords

3' 5' DI TERT BUTYLHYDROXYPHENYL; ANTIOXIDANT; FLAVONOID; INWARDLY RECTIFYING POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOGRAPHY; ARTICLE; BLOOD VESSEL INJURY; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; DENSITY; DOSE RESPONSE; DRUG EFFECT; ENDOTHELIUM LESION; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.X; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; RAT; SMOOTH MUSCLE RELAXATION;

EID: 11144284072     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-004-0966-x     Document Type: Article

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