Prediction of the outcome of genetic testing in HNPCC kindreds using the revised Amsterdam criteria and immunohistochemistry

Familial Cancer

Volumn 1, Issue 3-4, 2001, Pages 169-173

  Stormorken, Astrid T ^a   Müller, Wolfram ^b   Lemkemeyer, Britta ^b   Apold, Jaran ^c   Wijnen, Juul T ^d   Fodde, Riccardo ^d   Möslein, Gabriela ^b   Møller, Pal ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Family history; Hereditary non polyposis colorectal cancer (HNPCC); Immunohistochemistry (IHC); Mismatch repair (MMR) gene mutations

Indexed keywords

GENE PRODUCT; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6;

ADULT; ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DIAGNOSTIC TEST; FAMILY HISTORY; GENE MUTATION; GENETIC ANALYSIS; GERM LINE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MISMATCH REPAIR; MUTATIONAL ANALYSIS; NETHERLANDS; PEDIGREE; PRIORITY JOURNAL; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY;

ADENOCARCINOMA; ADENOMA; ADULT; BASE PAIR MISMATCH; CARRIER PROTEINS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA REPAIR; DNA, NEOPLASM; DNA-BINDING PROTEINS; FEMALE; GENETIC SCREENING; GERM-LINE MUTATION; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MIDDLE AGED; MUTS HOMOLOG 2 PROTEIN; NEOPLASM PROTEINS; NETHERLANDS; NUCLEAR PROTEINS; PREDICTIVE VALUE OF TESTS; PROTO-ONCOGENE PROTEINS; SENSITIVITY AND SPECIFICITY;

EID: 6444245421     PISSN: 13899600     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021151227983     Document Type: Article

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