Frontline: Peripheral priming of alloreactive T cells by the direct pathway of allorecognition

European Journal of Immunology

Volumn 34, Issue 12, 2004, Pages 3305-3314

  Baratin, Myriam ^a   Bonin, Karina ^a   Daniel, Claude ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

Alloreactivity; Graft rejection; Secondary lymphoid organs; T cell activation; Transgenic mice

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN RECOGNITION; ARTICLE; CLONAL VARIATION; CONTROLLED STUDY; GRAFT REJECTION; HISTOCOMPATIBILITY; IMMUNE RESPONSE; IMMUNOSTIMULATION; LYMPH NODE; LYMPHOID ORGAN; MALE; MOUSE; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; SENSITIZATION; SKIN ALLOGRAFT; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGEN PRESENTATION; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; GRAFT REJECTION; HOMEODOMAIN PROTEINS; INTERFERON TYPE II; ISOANTIGENS; MICE; MICE, TRANSGENIC; ORGAN TRANSPLANTATION; RECEPTORS, ANTIGEN, T-CELL; SKIN TRANSPLANTATION; T-LYMPHOCYTE SUBSETS; TIME FACTORS; TRANSPLANTATION IMMUNOLOGY;

EID: 10944261955     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200425309     Document Type: Article

References (29)

1. Bajenoff, M., Granjeaud, S. and Guarder, G., The strategy of T cell antigen-presenting cell encounter in antigen-draining lymph nodes revealed by imaging of initial T cell activation. J. Exp. Med. 2003. 198: 715-724.
2. Stoll, S., Delon, J., Brotz, T. M. and Germain, R. N., Dynamic imaging of T cell-dendritic cell interactions in lymph nodes. Science 2002. 296: 1873-1876.
3. Lakkis, F. G., Arakelov, A., Konieczny, B. T. and Inoue, Y., Immunologic 'ignorance' of vascularized organ transplants in the absence of secondary lymphoid tissue. Nat. Med. 2000. 6: 686-688.
4. Zhou, P., Hwang, K. W., Palucki, D., Kim, O., Newell, K. A., Fu, Y. X. and Alegre, M. L., Secondary lymphoid organs are important but not absolutely required for allograft responses. Am. J. Transplant. 2003. 3: 259-266.
5. Sayegh, M. H. and Carpenter, C. B., Role of indirect allorecognition in allograft rejection. Int. Rev. Immunol. 1996. 13: 221-229.
6. Game, D. S. and Lechler, R. I., Pathways of allorecognition: implications for transplantation tolerance. Transpl. Immunol. 2002. 10: 101-108.
7. Rogers, N. J. and Lechler, R. I., Allorecognition. Am. J. Transplant. 2001. 1: 97-102.
8. Sauvé, D., Baratin, M., Leduc, C., Bonin, K. and Daniel, C., Alloantibody production is regulated by CD4 T cells' alloreactive pathway, rather than precursor frequency or Th1/Th2 differentiation. Am. J. Transplant. 2004. 4: 1237-1245.
9. Daniel, C., Horvath, S. and Allen, P. M., A basis for alloreactivity: MHC helical residues broaden peptide recognition by the TCR. Immunity 1998. 8: 543-552.
10. Grakoui, A., Donermeyer, D. L., Kanagawa, O., Murphy, K. M. and Allen, P. M., TCR-independent pathways mediate the effects of antigen dose and altered peptide ligands on Th cell polarization. J. Immunol. 1999. 162: 1923-1930.
11. + T cell alloresponse using altered peptide ligands. J. Immunol. 1998. 160: 3244-3250.
12. Nelson, C. A., Vidavsky, I., Viner, N. J., Gross, M. L. and Unanue, E. R., Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules. Proc. Natl. Acad. Sci. U S A 1997. 94: 628-633.
13. Williams, C. B., Vidal, K., Donermeyer, D. L., Peterson, D. A., White, J. M. and Allen, P. M., In vivo expression of a TCR antagonist: T cells escape central tolerance but are antagonized in the periphery. J. Immunol. 1998. 161: 128-137.
14. Vetto, R. M. and Lawson, R. K., The role of vascular endothelium in the afferent pathway as suggested by the alymphatic renal homotransplant. Transplantation 1967. 5: 1537-1539.
15. Braun, M. Y., Grandjean, I., Feunou, P., Duban, L., Kiss, R., Goldman, M. and Lantz, O., Acute rejection in the absence of cognate recognition of allograft by T cells. J. Immunol. 2001. 166: 4879-4883.
16. Valujskikh, A., Matesic, D., Gilliam, A., Anthony, D., Haqqi, T. M. and Heeger, P. S., T cells reactive to a single immunodominant self-restricted allopeptide induce skin graft rejection in mice. J. Clin. Invest. 1998. 101: 1398-1407.
17. Benichou, G., Valujskikh, A. and Heeger, P. S., Contributions of direct and indirect T cell alloreactivity during allograft rejection in mice. J. Immunol. 1999. 162: 352-358.
18. Sandner, S. E., Salama, A. D., Houser, S. L., Palmer, E., Turka, L. A. and Sayegh, M. H., New TCR transgenic model for tracking allospecific CD4 T cell activation and tolerance in vivo. Am. J. Transplant. 2003. 3: 1242-1250.
19. + T cells through the indirect presentation pathway in vivo. J. Immunol. 2003. 171: 6510-6518.
20. Chalasani, G., Dai, Z., Konieczny, B. T., Baddoura, F. K. and Lakkis, F. G., Recall and propagation of allospecific memory T cells independent of secondary lymphoid organs. Proc. Natl. Acad. Sci. U S A 2002. 99: 6175-6180.
21. Feng, C., Woodside, K. J., Vance, B. A., El-Khoury, D., Canelles, M., Lee, J., Gress, R., Fowlkes, B. J., Shores, E. W. and Love, P. E., A potential role for CD69 in thymocyte emigration. Int. Immunol. 2002. 14: 535-544.
22. + T cells and trigger acute rejection: an alternative mechanism of allorecognition. Nat. Med. 2002. 8: 233-239.
23. Fan, L., Busser, B. W., Lifsted, T. Q., Oukka, M., Lo, D. and Laufer, T. M., Antigen presentation by keratinocytes directs autoimmune skin disease. Proc. Natl. Acad. Sci. U S A 2003. 100: 3386-3391.
24. + T cells. J. Immunol. 1999. 162: 5287-5298.
25. + T cell-dependent elimination of dendritic cells in vivo limits the induction of antitumor immunity. J. Immunol. 2000. 164: 3095-3101.
26. Martin-Fontecha, A., Sebastiani, S., Hopken, U. E., Uguccioni, M., Lipp, M., Lanzavecchia, A. and Sallusto, F., Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming. J. Exp. Med. 2003. 198: 615-621.
27. Rosenberg, A., Skin allograft rejection.In Colignan, J., Kruisbeek, A., Margulies, D. and Shevach, E. (Eds.) Current Protocols in Immunology. John Wiley & Sons, Inc., Bethesda 1991, pp 4.4.1-4.4.9.
28. Evavold, B. D. and Allen, P. M., Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand. Science 1991. 252: 1308-1310.
29. Norwich, K. H., Ramanathan, S. and Poussier, P., Kinetics of T cell turnover following thymectomy. Cell Prolif. 1999. 32: 195-201.