메뉴 건너뛰기




Volumn 36, Issue 4, 1999, Pages 289-304

Pharmacokinetics and potential interactions amongst antiretroviral agents used to treat patients with HIV infection

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; AMPRENAVIR; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIRETROVIRUS AGENT; CYTOCHROME P450; DELAVIRDINE; DIDANOSINE; DRUG METABOLIZING ENZYME; EFAVIRENZ; INDINAVIR; LAMIVUDINE; LIVER ENZYME; NELFINAVIR; NEVIRAPINE; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; STAVUDINE; VIRUS RNA; ZALCITABINE; ZIDOVUDINE;

EID: 0032955402     PISSN: 03125963     EISSN: None     Source Type: Journal    
DOI: 10.2165/00003088-199936040-00004     Document Type: Review
Times cited : (269)

References (101)
  • 1
    • 0019782357 scopus 로고
    • Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: Evidence of a new acquired cellular immunodeficiency
    • 1. Gottlieb MS, Schroff R, Schanker HM, et al. Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: evidence of a new acquired cellular immunodeficiency. N Engl J Med 1981; 305: 1425-31
    • (1981) N Engl J Med , vol.305 , pp. 1425-1431
    • Gottlieb, M.S.1    Schroff, R.2    Schanker, H.M.3
  • 2
    • 0031556787 scopus 로고    scopus 로고
    • HIV epidemic is far worse than thought
    • 2. Wise J. HIV epidemic is far worse than thought. BMJ 1997; 315: 1486
    • (1997) BMJ , vol.315 , pp. 1486
    • Wise, J.1
  • 3
    • 0030603841 scopus 로고    scopus 로고
    • Changing the natural history of HIV disease
    • 3. Feinberg MB. Changing the natural history of HIV disease. Lancet 1996; 348: 239-46
    • (1996) Lancet , vol.348 , pp. 239-246
    • Feinberg, M.B.1
  • 4
    • 10144244674 scopus 로고    scopus 로고
    • A trial comparing nucleoside monotherapy with combination therapy in HIV-infected adults with CD4 counts from 200-500 per cubic millimeter
    • 4. Hammer SM, Katzenstein DA, Hughes MD, et al. A trial comparing nucleoside monotherapy with combination therapy in HIV-infected adults with CD4 counts from 200-500 per cubic millimeter. N Engl J Med 1996; 335: 1081-90
    • (1996) N Engl J Med , vol.335 , pp. 1081-1090
    • Hammer, S.M.1    Katzenstein, D.A.2    Hughes, M.D.3
  • 5
    • 0030567824 scopus 로고    scopus 로고
    • Delta: A randomised double-blind controlled trial comparing combinations of zidovudine plus didanosine or zalcitabine with zidovudine alone in HIV-infected individuals
    • 5. Delta Coordinating Committee. Delta: a randomised double-blind controlled trial comparing combinations of zidovudine plus didanosine or zalcitabine with zidovudine alone in HIV-infected individuals. Lancet 1996; 348: 283-91
    • (1996) Lancet , vol.348 , pp. 283-291
  • 6
    • 0030997937 scopus 로고    scopus 로고
    • Randomised trial of addition of lamivudine or lamivudine plus loviride containing regimens for patients with HIV-1 infection: The CAESAR trial
    • 6. Caesar Coordinating Committee. Randomised trial of addition of lamivudine or lamivudine plus loviride containing regimens for patients with HIV-1 infection: the CAESAR trial. Lancet 1997; 349: 1413-21
    • (1997) Lancet , vol.349 , pp. 1413-1421
  • 7
    • 0442268112 scopus 로고    scopus 로고
    • A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimetre or less
    • 7. Hammer SM, Squires KE, Hughes MD, et al. A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimetre or less. N Engl J Med 1997; 337: 725-33
    • (1997) N Engl J Med , vol.337 , pp. 725-733
    • Hammer, S.M.1    Squires, K.E.2    Hughes, M.D.3
  • 8
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection
    • 8. Palella FJ, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N Engl J Med 1998; 338: 853-60
    • (1998) N Engl J Med , vol.338 , pp. 853-860
    • Palella, F.J.1    Delaney, K.M.2    Moorman, A.C.3
  • 9
    • 0030923798 scopus 로고    scopus 로고
    • Impact of combination therapy for HIV infection on inpatient census
    • 9. Torres RA, Barr M. Impact of combination therapy for HIV infection on inpatient census. N Engl J Med 1997; 336: 1531-2
    • (1997) N Engl J Med , vol.336 , pp. 1531-1532
    • Torres, R.A.1    Barr, M.2
  • 10
    • 0030596902 scopus 로고    scopus 로고
    • Antiretroviral drugs for AIDS
    • 10. Lipsky JJ. Antiretroviral drugs for AIDS. Lancet 1996; 348: 800-3
    • (1996) Lancet , vol.348 , pp. 800-803
    • Lipsky, J.J.1
  • 11
    • 0023266214 scopus 로고
    • The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex
    • 11. Fischl MA, Richman DD, Grieco MH, et al. The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. N Engl J Med 1987; 317: 185-91
    • (1987) N Engl J Med , vol.317 , pp. 185-191
    • Fischl, M.A.1    Richman, D.D.2    Grieco, M.H.3
  • 12
    • 0023475103 scopus 로고
    • 3′-Azido-3′-deoxythymidine triphosphate as an inhibitor and substrate of purified human immunodeficiency virus reverse transcriptase
    • 12. St Clair MH, Richards CA, Spector T, et al. 3′-Azido-3′-deoxythymidine triphosphate as an inhibitor and substrate of purified human immunodeficiency virus reverse transcriptase. Antimicrob Agents Chemother 1987; 31: 1972-7
    • (1987) Antimicrob Agents Chemother , vol.31 , pp. 1972-1977
    • St Clair, M.H.1    Richards, C.A.2    Spector, T.3
  • 13
    • 0028271687 scopus 로고
    • Structure of the binding site for non-nucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1
    • 13. Smerdon SJ, Jager J, Wang J, et al. Structure of the binding site for non-nucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1. Proc Natl Acad Sci USA 1994; 26: 3911-5
    • (1994) Proc Natl Acad Sci USA , vol.26 , pp. 3911-3915
    • Smerdon, S.J.1    Jager, J.2    Wang, J.3
  • 14
    • 0031024623 scopus 로고    scopus 로고
    • HIV-1 protease inhibitors. A review for clinicians
    • 14. Deeks SG, Smith M, Holodniy M, et al. HIV-1 protease inhibitors. A review for clinicians. JAMA 1997; 277: 145-53
    • (1997) JAMA , vol.277 , pp. 145-153
    • Deeks, S.G.1    Smith, M.2    Holodniy, M.3
  • 15
    • 0026579208 scopus 로고
    • The HIV-1 protease as a therapeutic target for AIDS
    • 15. Debouck C. The HIV-1 protease as a therapeutic target for AIDS. AIDS Res Human Retroviruses 1992; 8: 153-64
    • (1992) AIDS Res Human Retroviruses , vol.8 , pp. 153-164
    • Debouck, C.1
  • 16
    • 0030895312 scopus 로고    scopus 로고
    • Protease inhibitors in patients with HIV disease: Clinically important pharmacokinetic considerations
    • 16. Barry M, Gibbons S, Back D, et al. Protease inhibitors in patients with HIV disease: clinically important pharmacokinetic considerations. Clin Pharmacokinet 1997; 32: 194-209
    • (1997) Clin Pharmacokinet , vol.32 , pp. 194-209
    • Barry, M.1    Gibbons, S.2    Back, D.3
  • 17
    • 0345334246 scopus 로고    scopus 로고
    • Antiretroviral therapy for HIV infection in 1996: Recommendations of an international panel
    • 17. Carpenter CCJ, Fischl MA, Hammer SM, et al. Antiretroviral therapy for HIV infection in 1996: recommendations of an international panel. JAMA 1996; 276: 146-54
    • (1996) JAMA , vol.276 , pp. 146-154
    • Carpenter, C.C.J.1    Fischl, M.A.2    Hammer, S.M.3
  • 18
    • 0030935802 scopus 로고    scopus 로고
    • British HIV Association guidelines for antiretroviral treatment of HIV seropositive individuals
    • 18. BHIVA Guidelines Co-ordinating Committee. British HIV Association guidelines for antiretroviral treatment of HIV seropositive individuals. Lancet 1997; 349: 1086-92
    • (1997) Lancet , vol.349 , pp. 1086-1092
  • 19
    • 0007010412 scopus 로고    scopus 로고
    • Antiretroviral therapy for HIV infection in 1998. Updated recommendations of the International AIDS Society: USA panel
    • 19. Carpenter CCJ, Fischl MA, Hammer SM, et al. Antiretroviral therapy for HIV infection in 1998. Updated recommendations of the International AIDS Society: USA panel. JAMA 1998; 280: 78-86
    • (1998) JAMA , vol.280 , pp. 78-86
    • Carpenter, C.C.J.1    Fischl, M.A.2    Hammer, S.M.3
  • 20
    • 0031937159 scopus 로고    scopus 로고
    • Antiretroviral therapy for HIV infection: A knowledge based approach to drug selection and use
    • 20. Moyle GJ, Gazzard BG, Cooper DA, et al. Antiretroviral therapy for HIV infection: a knowledge based approach to drug selection and use. Drugs 1998; 55: 383-404
    • (1998) Drugs , vol.55 , pp. 383-404
    • Moyle, G.J.1    Gazzard, B.G.2    Cooper, D.A.3
  • 21
    • 0027978495 scopus 로고
    • Prevalence and patterns of use of concomitant medications among participants in three multicentre human immunodeficiency virus type 1 clinical trials
    • 21. Fogelman I, Lim L, Bassett R, et al. Prevalence and patterns of use of concomitant medications among participants in three multicentre human immunodeficiency virus type 1 clinical trials. J Acq Immune Def Syndromes 1994; 7: 1057-63
    • (1994) J Acq Immune Def Syndromes , vol.7 , pp. 1057-1063
    • Fogelman, I.1    Lim, L.2    Bassett, R.3
  • 22
    • 0019432894 scopus 로고
    • Iatrogenic illness on a general medical service at a university hospital
    • 22. Steel K, Gertman PM, Cresienze G, et al. Iatrogenic illness on a general medical service at a university hospital. N Engl J Med 1981; 304: 638-42
    • (1981) N Engl J Med , vol.304 , pp. 638-642
    • Steel, K.1    Gertman, P.M.2    Cresienze, G.3
  • 23
    • 0028911385 scopus 로고
    • Clinical pharmacokinetics of nucleoside antiretroviral agents
    • 23. Dudley MN. Clinical pharmacokinetics of nucleoside antiretroviral agents. J Infect Dis 1995; 171 Suppl. 2: S99-112
    • (1995) J Infect Dis , vol.171 , Issue.SUPPL. 2
    • Dudley, M.N.1
  • 24
    • 0030935086 scopus 로고    scopus 로고
    • Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions
    • 24. Bertz RJ, Granneman GR. Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions. Clin Pharmacokinet 1997; 32: 210-58
    • (1997) Clin Pharmacokinet , vol.32 , pp. 210-258
    • Bertz, R.J.1    Granneman, G.R.2
  • 25
    • 0031900668 scopus 로고    scopus 로고
    • Abacavir. Drugs
    • 25. Foster RH, Faulds D. Abacavir. Drugs 1998; 55: 729-36
    • (1998) , vol.55 , pp. 729-736
    • Foster, R.H.1    Faulds, D.2
  • 26
    • 0029591968 scopus 로고
    • Metabolism of zidovudine
    • 26. Veal GJ, Back DJ. Metabolism of zidovudine. Gen Pharmacol 1995; 26: 1469-75
    • (1995) Gen Pharmacol , vol.26 , pp. 1469-1475
    • Veal, G.J.1    Back, D.J.2
  • 27
    • 0029968585 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of zidovudine: An update
    • 27. Acosta EP, Page LM, Fletcher CV. Clinical pharmacokinetics of zidovudine: an update. Drug Dispos 1996; 30: 251-62
    • (1996) Drug Dispos , vol.30 , pp. 251-262
    • Acosta, E.P.1    Page, L.M.2    Fletcher, C.V.3
  • 28
    • 0025850455 scopus 로고
    • The effect of various drugs on the glucuronidation of zidovudine (azidothymidine; AZT) by human liver microsomes
    • 28. Sim SM, Back DJ, Breckenridge AM. The effect of various drugs on the glucuronidation of zidovudine (azidothymidine; AZT) by human liver microsomes. Br J Clin Pharmacol 1991; 32: 17-21
    • (1991) Br J Clin Pharmacol , vol.32 , pp. 17-21
    • Sim, S.M.1    Back, D.J.2    Breckenridge, A.M.3
  • 29
    • 0028229791 scopus 로고
    • Pharmacokinetics of zidovudine and dideoxyinosine alone and in combination in patients with the acquired immunodeficiency syndrome
    • 29. Barry M, Howe JL, Ormesher S, et al. Pharmacokinetics of zidovudine and dideoxyinosine alone and in combination in patients with the acquired immunodeficiency syndrome. Br J Clin Pharmacol 1994; 37: 421-6
    • (1994) Br J Clin Pharmacol , vol.37 , pp. 421-426
    • Barry, M.1    Howe, J.L.2    Ormesher, S.3
  • 30
    • 0027744108 scopus 로고
    • Combination therapy with zidovudine and didanosine compared with zidovudine alone in HIV-1 infection
    • 30. Collier AC, Coombs RW, Fischl MA, et al. Combination therapy with zidovudine and didanosine compared with zidovudine alone in HIV-1 infection. Ann Intern Med 1993; 119: 786-93
    • (1993) Ann Intern Med , vol.119 , pp. 786-793
    • Collier, A.C.1    Coombs, R.W.2    Fischl, M.A.3
  • 31
    • 0029084114 scopus 로고
    • Pharmacokinetics of simultaneously administered zidovudine and didanosine in HIV-seropositive male patients
    • 31. Sahai J, Gallicano K, Garber G, et al. Pharmacokinetics of simultaneously administered zidovudine and didanosine in HIV-seropositive male patients. J Acq Immune Def Syndromes 1995; 10: 54-60
    • (1995) J Acq Immune Def Syndromes , vol.10 , pp. 54-60
    • Sahai, J.1    Gallicano, K.2    Garber, G.3
  • 32
    • 0030899204 scopus 로고    scopus 로고
    • Lamivudine: A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in the management of HIV infection
    • 32. Perry CM, Faulds D. Lamivudine: a review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in the management of HIV infection. Drugs 1997; 53: 657-80
    • (1997) Drugs , vol.53 , pp. 657-680
    • Perry, C.M.1    Faulds, D.2
  • 33
    • 9244220064 scopus 로고    scopus 로고
    • Virological and immunological analysis of a triple combination pilot study with loviride, lamivudine and zidovudine in HIV-1-infected patients
    • 33. Staszewski S, Miller V, Rehmet S, et al. Virological and immunological analysis of a triple combination pilot study with loviride, lamivudine and zidovudine in HIV-1-infected patients. AIDS 1996; 10: F1-7
    • (1996) AIDS , vol.10
    • Staszewski, S.1    Miller, V.2    Rehmet, S.3
  • 34
    • 0028019610 scopus 로고
    • Pharmacokinetics of co-administered didanosine and stavudine in HIV-seropositive male patients
    • 34. Seifert RD, Stewart MB, Sramek JJ, et al. Pharmacokinetics of co-administered didanosine and stavudine in HIV-seropositive male patients. Br J Clin Pharmacol 1994; 38: 405-10
    • (1994) Br J Clin Pharmacol , vol.38 , pp. 405-410
    • Seifert, R.D.1    Stewart, M.B.2    Sramek, J.J.3
  • 35
    • 0001964670 scopus 로고    scopus 로고
    • The safety and pharmacokinetics of GW1592U89, zidovudine (ZDV) and lamivudine (3TC) alone and in combination after single-dose administration in HIV-infected patients
    • 35. Symonds WT, McDowell J, Chittick G, et al. The safety and pharmacokinetics of GW1592U89, zidovudine (ZDV) and lamivudine (3TC) alone and in combination after single-dose administration in HIV-infected patients [abstract P19]. AIDS 1996; 10 Suppl. 2: S23
    • (1996) AIDS , vol.10 , Issue.SUPPL. 2
    • Symonds, W.T.1    McDowell, J.2    Chittick, G.3
  • 36
    • 0028227986 scopus 로고
    • Zidovudine pharmacokinetics in zidovudine-induced bone marrow toxicity
    • 36. Barry M, Howe JL, Back DJ, et al. Zidovudine pharmacokinetics in zidovudine-induced bone marrow toxicity. Br J Clin Pharmacol 1994; 37: 7-12
    • (1994) Br J Clin Pharmacol , vol.37 , pp. 7-12
    • Barry, M.1    Howe, J.L.2    Back, D.J.3
  • 37
    • 0026742359 scopus 로고
    • Pharmacokinetics of zidovudine phosphorylation in patients infected with the human immunodeficiency virus
    • 37. Stretcher BN, Pesce AJ, Hurtubise PE, et al. Pharmacokinetics of zidovudine phosphorylation in patients infected with the human immunodeficiency virus. Ther Drug Monit 1992; 14: 281-5
    • (1992) Ther Drug Monit , vol.14 , pp. 281-285
    • Stretcher, B.N.1    Pesce, A.J.2    Hurtubise, P.E.3
  • 38
    • 0029768927 scopus 로고    scopus 로고
    • The effect of zidovudine dose on the formation of intracellular phosphorylated metabolites
    • 38. Barry M, Khoo S, Back DJ, et al. The effect of zidovudine dose on the formation of intracellular phosphorylated metabolites. AIDS 1996; 10: 1361-7
    • (1996) AIDS , vol.10 , pp. 1361-1367
    • Barry, M.1    Khoo, S.2    Back, D.J.3
  • 39
    • 85070037073 scopus 로고    scopus 로고
    • Pharmacokinetics (PK) of lamivudine (3TC) phosphorylation in peripheral blood mono-nuclear cells (PBMC) from HIV-infected patients
    • Jun 28-Jul 3; Geneva
    • 39. Moore K, Barrett JE, Shaw S, et al. Pharmacokinetics (PK) of lamivudine (3TC) phosphorylation in peripheral blood mono-nuclear cells (PBMC) from HIV-infected patients [abstract 42470]. 12th World AIDS Conference; 1998 Jun 28-Jul 3; Geneva.
    • (1998) 12th World AIDS Conference
    • Moore, K.1    Barrett, J.E.2    Shaw, S.3
  • 40
    • 0030982931 scopus 로고    scopus 로고
    • 1592U89, A novel carbocyclic nucleoside analogue with potent selective anti-human immunodeficiency virus activity
    • 40. Daluge SM, Good SS, Faletto MB, et al. 1592U89, a novel carbocyclic nucleoside analogue with potent selective anti-human immunodeficiency virus activity. Antimicrob Agents Chemother 1997; 41: 1082-93
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1082-1093
    • Daluge, S.M.1    Good, S.S.2    Faletto, M.B.3
  • 41
    • 0029782824 scopus 로고    scopus 로고
    • Intracellular metabolism of zidovudine and stavudine in combination
    • 41. Hoggard P, Khoo S, Barry M, et al. Intracellular metabolism of zidovudine and stavudine in combination. J Infect Dis 1996; 174:671-2
    • (1996) J Infect Dis , vol.174 , pp. 671-672
    • Hoggard, P.1    Khoo, S.2    Barry, M.3
  • 42
  • 43
    • 0024405549 scopus 로고
    • Cellular pharmacology of 2′,3′-dideoxy-2′,3′-didehydrothymidine, a nucleoside analog active against human immunodeficiency virus
    • 43. Ho H-T, Hitchcock MJM. Cellular pharmacology of 2′,3′-dideoxy-2′,3′-didehydrothymidine, a nucleoside analog active against human immunodeficiency virus. Antimicrob Agents Chemother 1989; 33: 844-9
    • (1989) Antimicrob Agents Chemother , vol.33 , pp. 844-849
    • Ho, H.-T.1    Hitchcock, M.J.M.2
  • 44
    • 0030042695 scopus 로고    scopus 로고
    • Lamivudine or stavudine in two-and three-drug combinations against human immunodeficiency virus type 1 replication in vitro
    • 44. Merrill DP, Moonis M, Chou T-C, et al. Lamivudine or stavudine in two-and three-drug combinations against human immunodeficiency virus type 1 replication in vitro. J Infect Dis 1996; 173: 355-64
    • (1996) J Infect Dis , vol.173 , pp. 355-364
    • Merrill, D.P.1    Moonis, M.2    Chou, T.-C.3
  • 45
    • 0003229807 scopus 로고    scopus 로고
    • Combination zidovudine (ZDV) and stavudine (d4T) therapy versus other nucleosides: Report of two randomised trials ACTG 290 and 298
    • Feb 1-5; Chicago
    • 45. Havlir DV, Freidland G, Pollard R, et al. Combination zidovudine (ZDV) and stavudine (d4T) therapy versus other nucleosides: report of two randomised trials ACTG 290 and 298 [abstract]. 5th Conference on Retroviruses and Opportunistic Infections; 1998 Feb 1-5; Chicago
    • (1998) 5th Conference on Retroviruses and Opportunistic Infections
    • Havlir, D.V.1    Freidland, G.2    Pollard, R.3
  • 46
    • 0029869720 scopus 로고    scopus 로고
    • Interaction between 3TC (lamivudine) and other nucleoside analogues for intracellular phosphorylation
    • 46. Veal GJ, Hoggard PG, Barry MG, et al. Interaction between 3TC (lamivudine) and other nucleoside analogues for intracellular phosphorylation. AIDS 1996; 10: 546-8
    • (1996) AIDS , vol.10 , pp. 546-548
    • Veal, G.J.1    Hoggard, P.G.2    Barry, M.G.3
  • 47
    • 0030888216 scopus 로고    scopus 로고
    • In vitro screening of nucleoside analog combinations for potential use in anti-HIV therapy
    • 47. Veal GJ, Barry MG, Khoo SH, et al. In vitro screening of nucleoside analog combinations for potential use in anti-HIV therapy. AIDS Res Human Retroviruses 1997; 13: 481-4
    • (1997) AIDS Res Human Retroviruses , vol.13 , pp. 481-484
    • Veal, G.J.1    Barry, M.G.2    Khoo, S.H.3
  • 48
    • 0030776777 scopus 로고    scopus 로고
    • Lamivudine (3TC) phosphorylation and drug interactions in vitro
    • 48. Kewn S, Veal GJ, Hoggard PG, et al. Lamivudine (3TC) phosphorylation and drug interactions in vitro. Biochem Pharmacol 1997; 54: 589-95
    • (1997) Biochem Pharmacol , vol.54 , pp. 589-595
    • Kewn, S.1    Veal, G.J.2    Hoggard, P.G.3
  • 49
    • 10544249459 scopus 로고    scopus 로고
    • Efficacy of triple combination therapy with zidovudine (ZDV) plus zalcitabine (ddC) plus lamivudine (3TC) versus double (ZDV + 3TC) combination therapy in patients previously treated with ZDV + ddC
    • 49. Ruiz L, Romeu J, Martinez-Picado J, et al. Efficacy of triple combination therapy with zidovudine (ZDV) plus zalcitabine (ddC) plus lamivudine (3TC) versus double (ZDV + 3TC) combination therapy in patients previously treated with ZDV + ddC. AIDS 1996; 10: F61-6
    • (1996) AIDS , vol.10
    • Ruiz, L.1    Romeu, J.2    Martinez-Picado, J.3
  • 50
    • 0027939485 scopus 로고
    • Effects of dideoxymosine and dideoxycytidine on the intracellular phosphorylation of zidovudine in human mononuclear cells
    • 50. Veal GJ, Wild MJ, Barry MG, et al. Effects of dideoxymosine and dideoxycytidine on the intracellular phosphorylation of zidovudine in human mononuclear cells. Br J Clin Pharmacol 1994; 38: 323-8
    • (1994) Br J Clin Pharmacol , vol.38 , pp. 323-328
    • Veal, G.J.1    Wild, M.J.2    Barry, M.G.3
  • 51
    • 0028886715 scopus 로고
    • Zalcitabine (ddC) phosphorylation and drug interactions
    • 51. Veal GJ, Barry MG, Back DJ. Zalcitabine (ddC) phosphorylation and drug interactions. Antiviral Chem Chemother 1995; 6: 379-84
    • (1995) Antiviral Chem Chemother , vol.6 , pp. 379-384
    • Veal, G.J.1    Barry, M.G.2    Back, D.J.3
  • 52
    • 85070028221 scopus 로고    scopus 로고
    • The intracellular activation of ddI (didanosine) in combination with other nucleoside analogues in vitro
    • 52. Kewn S, Hoggard P, Veal GJ, et al. The intracellular activation of ddI (didanosine) in combination with other nucleoside analogues in vitro. Br J Clin Pharmacol 1998; 45: 518P
    • (1998) Br J Clin Pharmacol , vol.45
    • Kewn, S.1    Hoggard, P.2    Veal, G.J.3
  • 54
    • 85070030181 scopus 로고    scopus 로고
    • Altiphar: A study to assess the pharmacologic and virologic mechanisms contributing to decreased antiviral activity of a stavudine/lamivudine combination in zidovudine-experienced patients
    • Oct 11-15; Hamburg, Germany
    • 54. Sommadossi JP, Calvez V, Xie M-Y, et al. Altiphar: a study to assess the pharmacologic and virologic mechanisms contributing to decreased antiviral activity of a stavudine/lamivudine combination in zidovudine-experienced patients [abstract]. 6th European Conference on Clinical Aspects and Treatment of HIV Infection; 1997 Oct 11-15; Hamburg, Germany
    • (1997) 6th European Conference on Clinical Aspects and Treatment of Hiv Infection
    • Sommadossi, J.P.1    Calvez, V.2    Xie, M.-Y.3
  • 55
    • 0003250298 scopus 로고    scopus 로고
    • Impairment of stavudine (d4T) phosphorylation in patients receiving a combination of zidovudine (ZDV) and d4T (ACTG 290)
    • Feb 1-5; Chicago
    • 55. Sommadossi JP, Zhou XJ, Moore J, et al. Impairment of stavudine (d4T) phosphorylation in patients receiving a combination of zidovudine (ZDV) and d4T (ACTG 290) [abstract]. 5th Conference on Retroviruses and Opportunistic Infections; 1998 Feb 1-5; Chicago
    • (1998) 5th Conference on Retroviruses and Opportunistic Infections
    • Sommadossi, J.P.1    Zhou, X.J.2    Moore, J.3
  • 56
    • 0013545817 scopus 로고    scopus 로고
    • Quantification of d4T triphosphate (d4TTP) in ZDV naive and ZDV experienced HIV infected individuals by an enzymatic assay
    • Jan 31-Feb 4; Chicago
    • 56. Phiboonbanakit D, Lloyd J, Khoo S, et al. Quantification of d4T triphosphate (d4TTP) in ZDV naive and ZDV experienced HIV infected individuals by an enzymatic assay [abstract 487]. 6th Conference on Retroviruses and Opportunistic Infections; 1999 Jan 31-Feb 4; Chicago.
    • (1999) 6th Conference on Retroviruses and Opportunistic Infections
    • Phiboonbanakit, D.1    Lloyd, J.2    Khoo, S.3
  • 57
    • 0004795848 scopus 로고    scopus 로고
    • Indinavir (MK 639) drug interaction studies
    • Jul 7-12; Vancouver
    • 57. The Indinavir (MK 639) Pharmacokinetic Study Group. Indinavir (MK 639) drug interaction studies [abstract Mo.B.174]. XIth International Conference on AIDS; 1996 Jul 7-12; Vancouver
    • (1996) XIth International Conference on AIDS
  • 58
    • 0003334318 scopus 로고    scopus 로고
    • Potent and sustained release antiretroviral activity of indinavir (IDV) in combination with zidovudine (ZDV) and lamivudine (3TC)
    • Jan 28-Feb 2; Washington, DC
    • 58. Gulick R, Mellors J, Havlir D, et al. Potent and sustained release antiretroviral activity of indinavir (IDV) in combination with zidovudine (ZDV) and lamivudine (3TC) [abstract LB7]. 3rd Conference on Retroviruses and Opportunistic Infections; 1996 Jan 28-Feb 2; Washington, DC
    • (1996) 3rd Conference on Retroviruses and Opportunistic Infections
    • Gulick, R.1    Mellors, J.2    Havlir, D.3
  • 59
    • 0029850308 scopus 로고    scopus 로고
    • Didanosine: An update on its antiviral activity, pharmacological properties and therapeutic efficacy in the management of HIV disease
    • 59. Perry CM, Balflour JA. Didanosine: an update on its antiviral activity, pharmacological properties and therapeutic efficacy in the management of HIV disease. Drugs 1996; 52: 928-62
    • (1996) Drugs , vol.52 , pp. 928-962
    • Perry, C.M.1    Balflour, J.A.2
  • 60
    • 0032580479 scopus 로고    scopus 로고
    • HIV protease inhibitors
    • 60. Flexner C. HIV protease inhibitors. N Engl J Med 1998; 338: 1281-92
    • (1998) N Engl J Med , vol.338 , pp. 1281-1292
    • Flexner, C.1
  • 61
    • 0009599479 scopus 로고    scopus 로고
    • The single-dose pharmacokinetics of 141W94, zidovudine, and lamivudine when administered alone and in two-and three-drug combinations
    • Oct 11-15; Hamburg, Germany
    • 61. Sadler BM, Wald JA, Lou Y, et al. The single-dose pharmacokinetics of 141W94, zidovudine, and lamivudine when administered alone and in two-and three-drug combinations [abstract]. 6th European Conference on Clinical Aspects and Treatment of HIV-Infection; 1997 Oct 11-15; Hamburg, Germany
    • (1997) 6th European Conference on Clinical Aspects and Treatment of HIV-Infection
    • Sadler, B.M.1    Wald, J.A.2    Lou, Y.3
  • 62
    • 0002677868 scopus 로고    scopus 로고
    • In vivo and in vitro studies of the potential for drug interactions involving the antiretroviral 1592 (abacavir) in humans
    • Feb 1-5; Chicago
    • 62. Ravitch JR, Bryant BJ, Reese MJ, et al. In vivo and in vitro studies of the potential for drug interactions involving the antiretroviral 1592 (abacavir) in humans [abstract]. 5th Conference on Retroviruses and Opportunistic Infections; 1998 Feb 1-5; Chicago
    • (1998) 5th Conference on Retroviruses and Opportunistic Infections
    • Ravitch, J.R.1    Bryant, B.J.2    Reese, M.J.3
  • 63
    • 0031963429 scopus 로고    scopus 로고
    • Effect of protease inhibitors on nucleoside analogue phosphorylation in vitro
    • 63. Hoggard PG, Mannion V, Barry MG, et al. Effect of protease inhibitors on nucleoside analogue phosphorylation in vitro. Br J Clin Pharmacol 1998; 45: 164-7
    • (1998) Br J Clin Pharmacol , vol.45 , pp. 164-167
    • Hoggard, P.G.1    Mannion, V.2    Barry, M.G.3
  • 64
    • 0029761518 scopus 로고    scopus 로고
    • Nevirapine: A review of its development, pharmacological profile and potential for clinical use
    • 64. Murphy RL, Montaner J. Nevirapine: a review of its development, pharmacological profile and potential for clinical use. Exp Opin Invest Drugs 1996; 5: 1183-99
    • (1996) Exp Opin Invest Drugs , vol.5 , pp. 1183-1199
    • Murphy, R.L.1    Montaner, J.2
  • 65
    • 0030317268 scopus 로고    scopus 로고
    • Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in patients with HIV-1 infection
    • 65. D'Aquila RT, Hughes MD, Johnson VA, et al. Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in patients with HIV-1 infection. Ann Intern Med 1996; 124: 1019-30
    • (1996) Ann Intern Med , vol.124 , pp. 1019-1030
    • D'Aquila, R.T.1    Hughes, M.D.2    Johnson, V.A.3
  • 66
    • 0031020802 scopus 로고    scopus 로고
    • Single-dose pharmacokinetics of delavirdine mesylate and didanosine in patients with human immunodeficiency virus infection
    • 66. Morse GD, Fischl MA, Shelton MJ, et al. Single-dose pharmacokinetics of delavirdine mesylate and didanosine in patients with human immunodeficiency virus infection. Antimicrob Agents Chemother 1997; 41: 169-74
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 169-174
    • Morse, G.D.1    Fischl, M.A.2    Shelton, M.J.3
  • 67
    • 0032441604 scopus 로고    scopus 로고
    • Efavirenz
    • 67. Adkin JC, Noble S. Efavirenz. Drugs 1998; 56 (6): 1055-64
    • (1998) Drugs , vol.56 , Issue.6 , pp. 1055-1064
    • Adkin, J.C.1    Noble, S.2
  • 68
    • 0031892546 scopus 로고    scopus 로고
    • Antiretroviral therapy for patients with HIV disease
    • 68. Barry M, Mulcahy F, Back DJ. Antiretroviral therapy for patients with HIV disease. Br J Clin Pharmacol 1998; 45: 221-8
    • (1998) Br J Clin Pharmacol , vol.45 , pp. 221-228
    • Barry, M.1    Mulcahy, F.2    Back, D.J.3
  • 69
    • 0344015847 scopus 로고    scopus 로고
    • Virological treatment failure of protease inhibitor therapy in an unselected cohort of HIV-infected patients
    • 69. Fätkenheuer G, Theisen A, Rockstroh J, et al. Virological treatment failure of protease inhibitor therapy in an unselected cohort of HIV-infected patients. AIDS 1997; 11: F113-6
    • (1997) AIDS , vol.11
    • Fätkenheuer, G.1    Theisen, A.2    Rockstroh, J.3
  • 70
    • 0025035723 scopus 로고
    • Enzyme induction and inhibition
    • 70. Barry M, Feely J. Enzyme induction and inhibition. Pharmacol Ther 1990; 48: 71-94
    • (1990) Pharmacol Ther , vol.48 , pp. 71-94
    • Barry, M.1    Feely, J.2
  • 71
    • 0030852009 scopus 로고    scopus 로고
    • Differential inhibition of cytochrome P450 isoforms by the protease inhibitors ritonavir, saquinavir, and indinavir
    • 71. Eagling VA, Back DJ, Barry MG. Differential inhibition of cytochrome P450 isoforms by the protease inhibitors ritonavir, saquinavir, and indinavir. Br J Clin Pharmacol 1997; 44: 190-4
    • (1997) Br J Clin Pharmacol , vol.44 , pp. 190-194
    • Eagling, V.A.1    Back, D.J.2    Barry, M.G.3
  • 72
    • 0031931102 scopus 로고    scopus 로고
    • Protease inhibitors as inhibitors of human cytochromes P450: High risk associated with ritonavir
    • 72. Von Moltke LL, Greenblatt DJ, Grassi JM, et al. Protease inhibitors as inhibitors of human cytochromes P450: high risk associated with ritonavir. J Clin Pharmacol 1998; 38: 106-11
    • (1998) J Clin Pharmacol , vol.38 , pp. 106-111
    • Von Moltke, L.L.1    Greenblatt, D.J.2    Grassi, J.M.3
  • 74
    • 0029897059 scopus 로고    scopus 로고
    • Saquinavir a review of its pharmacology and clinical potential in the management of HIV infection
    • 74. Noble S, Faulds D. Saquinavir a review of its pharmacology and clinical potential in the management of HIV infection. Drugs 1996; 52 (1): 93-112
    • (1996) Drugs , vol.52 , Issue.1 , pp. 93-112
    • Noble, S.1    Faulds, D.2
  • 75
    • 14544302432 scopus 로고    scopus 로고
    • Investigations of nelfinavir mesylate (NFV) pharmacokinetic (PK) interactions with indinavir (IDV) and ritonavir (RTV)
    • Jan 28-Feb 2; Washington, DC
    • 75. Yuen G, Anderson R, Daniels R, et al. Investigations of nelfinavir mesylate (NFV) pharmacokinetic (PK) interactions with indinavir (IDV) and ritonavir (RTV) [abstract]. 4th Conference on Retroviruses and Opportunistic Infections; 1997 Jan 28-Feb 2; Washington, DC
    • (1997) 4th Conference on Retroviruses and Opportunistic Infections
    • Yuen, G.1    Anderson, R.2    Daniels, R.3
  • 76
    • 0002261225 scopus 로고    scopus 로고
    • Pharmacokinetics of 141W94 and indinavir (IDV) after single-dose coadministration in HIV-positive volunteers
    • Sep 28-Oct 1; Toronto, Canada
    • 76. Sadler BM, Eron J, Wakeford J, et al. Pharmacokinetics of 141W94 and indinavir (IDV) after single-dose coadministration in HIV-positive volunteers [abstract A-56]. 37th Interscience Conference on Antimicrobial Agents and Chemotherapy; 1997 Sep 28-Oct 1; Toronto, Canada
    • (1997) 37th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Sadler, B.M.1    Eron, J.2    Wakeford, J.3
  • 77
    • 0032510173 scopus 로고    scopus 로고
    • Ritonavir pharmacokinetics alone and in combination with saquinavir in HIV infected patients
    • 77. Merry C, Barry MG, Mulcahy F, et al. Ritonavir pharmacokinetics alone and in combination with saquinavir in HIV infected patients. AIDS 1998; 12: 325-7
    • (1998) AIDS , vol.12 , pp. 325-327
    • Merry, C.1    Barry, M.G.2    Mulcahy, F.3
  • 79
    • 0003352345 scopus 로고    scopus 로고
    • Saquinavir soft gel capsule (Fortovase): Pharmacokinetics and drug interactions
    • Feb 1-5; Chicago
    • 79. Buss N, Fortovase Study Group. Saquinavir soft gel capsule (Fortovase): pharmacokinetics and drug interactions [abstract]. 5th Conference on Retroviruses and Opportunistic Infections; 1998 Feb 1-5; Chicago
    • (1998) 5th Conference on Retroviruses and Opportunistic Infections
    • Buss, N.1
  • 80
    • 0031054507 scopus 로고    scopus 로고
    • Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected patients
    • 80. Merry C, Barry MG, Mulcahy F, et al. Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected patients. AIDS 1997; 11: F29-33
    • (1997) AIDS , vol.11
    • Merry, C.1    Barry, M.G.2    Mulcahy, F.3
  • 81
    • 0003217559 scopus 로고    scopus 로고
    • Nelfinavir mesylate (NFV) increases saquinavir-soft gel capsule (SQV-SGC) exposure in HIV+ patients
    • Jan 28-Feb 2; Washington, DC
    • 81. Kravcik S, Sahai J, Kerr B, et al. Nelfinavir mesylate (NFV) increases saquinavir-soft gel capsule (SQV-SGC) exposure in HIV+ patients [abstract]. 4th Conference on Retroviruses and Opportunistic Infections; 1997 Jan 28-Feb 2; Washington, DC
    • (1997) 4th Conference on Retroviruses and Opportunistic Infections
    • Kravcik, S.1    Sahai, J.2    Kerr, B.3
  • 82
    • 0030830568 scopus 로고    scopus 로고
    • Saquinavir pharmacokinetics alone and in combination with nelfinavir in HIV-infected patients
    • 82. Merry C, Barry MG, Mulcahy F, et al. Saquinavir pharmacokinetics alone and in combination with nelfinavir in HIV-infected patients. AIDS 1997; 11: F117-20
    • (1997) AIDS , vol.11
    • Merry, C.1    Barry, M.G.2    Mulcahy, F.3
  • 83
    • 0002645877 scopus 로고    scopus 로고
    • Pharmacokinetic drug interactions with amprenavir
    • Jun 28-Jul 3; Geneva, Switzerland
    • 83. Sadler SM, Gillotin C, Chittick GE, et al. Pharmacokinetic drug interactions with amprenavir [abstract 12389], 12th World AIDS Conference; 1998 Jun 28-Jul 3; Geneva, Switzerland
    • (1998) 12th World Aids Conference
    • Sadler, S.M.1    Gillotin, C.2    Chittick, G.E.3
  • 84
    • 85070035676 scopus 로고    scopus 로고
    • Safety and efficacy of reduced doses of ritonavir (RTV) plus saquinavir (SQV) in the treatment of AIDS patients in Brazil
    • Jun 28-Jul 3; Geneva, Switzerland
    • 84. Brites C, Alcantara AP, Gimbo A, et al. Safety and efficacy of reduced doses of ritonavir (RTV) plus saquinavir (SQV) in the treatment of AIDS patients in Brazil [abstract 12114]. 12th World AIDS Conference; 1998 Jun 28-Jul 3; Geneva, Switzerland
    • (1998) 12th World Aids Conference
    • Brites, C.1    Alcantara, A.P.2    Gimbo, A.3
  • 86
    • 0013525364 scopus 로고    scopus 로고
    • Effect of nevirapine (NVP) on pharmacokinetics (PK) of indinavir (IDV) in HIV-1 patients
    • Jan 28-Feb 2; Washington, DC
    • 86. Gagnier P, Myers M, Lamson M, et al. Effect of nevirapine (NVP) on pharmacokinetics (PK) of indinavir (IDV) in HIV-1 patients [abstract]. 4th Conference on Retroviruses and Opportunistic Infections; 1997 Jan 28-Feb 2; Washington, DC
    • (1997) 4th Conference on Retroviruses and Opportunistic Infections
    • Gagnier, P.1    Myers, M.2    Lamson, M.3
  • 88
    • 2042453710 scopus 로고    scopus 로고
    • Effect of nevirapine (NVP) on pharmacokinetics of (PK) of ritonavir (RTV) in HIV-1 patients
    • Jan 28-Feb 2; Washington, DC
    • 88. Lamson M, Gagnier P, Greguski R, et al. Effect of nevirapine (NVP) on pharmacokinetics of (PK) of ritonavir (RTV) in HIV-1 patients [abstract]. 4th Conference on Retroviruses and Opportunistic Infections; 1997 Jan 28-Feb 2; Washington, DC
    • (1997) 4th Conference on Retroviruses and Opportunistic Infections
    • Lamson, M.1    Gagnier, P.2    Greguski, R.3
  • 90
    • 0031959676 scopus 로고    scopus 로고
    • Variability in trough plasma saquinavir concentrations in HIV patients: A case for therapeutic drug monitoring
    • 90. Barry MG, Merry C, Lloyd J, et al. Variability in trough plasma saquinavir concentrations in HIV patients: a case for therapeutic drug monitoring. Br J Clin Pharmacol 1998; 45: 501-2
    • (1998) Br J Clin Pharmacol , vol.45 , pp. 501-502
    • Barry, M.G.1    Merry, C.2    Lloyd, J.3
  • 91
    • 0032500016 scopus 로고    scopus 로고
    • The pharmacokinetics of combination therapy with nelfinavir plus nevirapine
    • 91. Merry C, Barry MG, Mulcahy F, et al. The pharmacokinetics of combination therapy with nelfinavir plus nevirapine. AIDS 1998; 12: 1163-7
    • (1998) AIDS , vol.12 , pp. 1163-1167
    • Merry, C.1    Barry, M.G.2    Mulcahy, F.3
  • 92
    • 0003272510 scopus 로고    scopus 로고
    • Stavudine (d4T), nelfinavir (NFV) and nevirapine (NVP): Preliminary safety, activity and pharmacokinetic (PK) interactions
    • Feb 2-5; Chicago
    • 92. Skowron G, Leoung G, Dusek A, et al. Stavudine (d4T), nelfinavir (NFV) and nevirapine (NVP): preliminary safety, activity and pharmacokinetic (PK) interactions [abstract]. 5th Conference on Retroviruses and Opportunistic Infections; 1998 Feb 2-5; Chicago
    • (1998) 5th Conference on Retroviruses and Opportunistic Infections
    • Skowron, G.1    Leoung, G.2    Dusek, A.3
  • 93
    • 0003237186 scopus 로고    scopus 로고
    • Pharmacokinetics of efavirenz. (EFV) and ritonavir (RIT) after multiple oral doses in healthy volunteers
    • Jun 28-Jul 3; Geneva, Switzerland
    • 93. Fiske W, Benedek IH, Joseph JL, et al. Pharmacokinetics of efavirenz. (EFV) and ritonavir (RIT) after multiple oral doses in healthy volunteers [abstract 42269]. 12th World AIDS Conference; 1998 Jun 28-Jul 3; Geneva, Switzerland
    • (1998) 12th World AIDS Conference
    • Fiske, W.1    Benedek, I.H.2    Joseph, J.L.3
  • 94
    • 0001835030 scopus 로고    scopus 로고
    • Pharmacokinetic interaction between efavirenz (EFV) and nelfinavir mesylate (NFV) in healthy volunteers
    • Feb 2-5; Chicago
    • 94. Fiske WD, Benedek IH, White SJ, et al. Pharmacokinetic interaction between efavirenz (EFV) and nelfinavir mesylate (NFV) in healthy volunteers [abstract]. 5th Conference on Retroviruses and Opportunistic Infections; 1998 Feb 2-5; Chicago
    • (1998) 5th Conference on Retroviruses and Opportunistic Infections
    • Fiske, W.D.1    Benedek, I.H.2    White, S.J.3
  • 96
    • 0001925810 scopus 로고    scopus 로고
    • Delavirdine and marketed protease inhibitors: Pharmacokinetic interaction studies in healthy volunteers
    • Jan 28-Feb 2; Washington, DC
    • 96. Cox SR, Ferry JJ, Batts DH, et al. Delavirdine and marketed protease inhibitors: pharmacokinetic interaction studies in healthy volunteers [abstract]. 4th Conference on Retroviruses and Opportunistic Infections; 1997 Jan 28-Feb 2; Washington, DC
    • (1997) 4th Conference on Retroviruses and Opportunistic Infections
    • Cox, S.R.1    Ferry, J.J.2    Batts, D.H.3
  • 97
    • 0013482265 scopus 로고    scopus 로고
    • Delavirdine (DLV) and indinavir (IDV): A pharmacokinetic (PK) drug-drug interaction study in healthy adult volunteers
    • Jan 28-Feb 2; Washington, DC
    • 97. Ferry JJ, Herman BD, Cox SR, et al. Delavirdine (DLV) and indinavir (IDV): a pharmacokinetic (PK) drug-drug interaction study in healthy adult volunteers [abstract]. 4th Conference on Retroviruses and Opportunistic Infections; 1997 Jan 28-Feb 2; Washington, DC
    • (1997) 4th Conference on Retroviruses and Opportunistic Infections
    • Ferry, J.J.1    Herman, B.D.2    Cox, S.R.3
  • 99
    • 0000748344 scopus 로고    scopus 로고
    • Delavirdine (DLV) and nelfinavir (NFV): A pharmacokinetic (PK) drug drug interaction study in healthy adult volunteers
    • Feb 2-5; Chicago
    • 99. Cox SR, Schneck DW, Herman BD, et al. Delavirdine (DLV) and nelfinavir (NFV): a pharmacokinetic (PK) drug drug interaction study in healthy adult volunteers [abstract]. 5th Conference on Retroviruses and Opportunistic Infections; 1998 Feb 2-5; Chicago
    • (1998) 5th Conference on Retroviruses and Opportunistic Infections
    • Cox, S.R.1    Schneck, D.W.2    Herman, B.D.3
  • 100
    • 0031914446 scopus 로고    scopus 로고
    • Saquinavir soft-gel capsule formulation: A review of its use in patients with HIV infection
    • 100. Perry CM, Noble S. Saquinavir soft-gel capsule formulation: a review of its use in patients with HIV infection. Drugs 1998; 55: 461-86
    • (1998) Drugs , vol.55 , pp. 461-486
    • Perry, C.M.1    Noble, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.