Automatic mass spectrometry method development for drug discovery: Application in metabolic stability assays

Rapid Communications in Mass Spectrometry

Volumn 18, Issue 24, 2004, Pages 3105-3112

  Chovan, Linda E ^a   Black Schaefer, Candace ^a   Dandliker, Peter J ^a   Lau, Yau Yi ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOMATION; BIOCHEMISTRY; DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; METABOLISM; THROUGHPUT;

AUTOMATED SYSTEMS; DRUG DISCOVERY APPLICATIONS; HIGH-THROUGHPUT; IN-VITRO; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY; METABOLIC STABILITY; METHOD DEVELOPMENT; ORGANIC SYNTHESIS; ROBOTIC SYSTEMS; VITRO INCUBATION;

MASS SPECTROMETRY;

ACCURACY; ARTICLE; ASSAY; AUTOMATIC MASS SPECTROMETRY; COMPUTER PROGRAM; DATA ANALYSIS; DRUG DEVELOPMENT; DRUG PROTEIN BINDING; DRUG STABILITY; HIGH THROUGHPUT SCREENING; IN VITRO STUDY; LABORATORY AUTOMATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLIC STABILITY ASSAY; MICROSOME; ROBOTICS; SAMPLER; SYNTHESIS; TANDEM MASS SPECTROMETRY; TIME;

EID: 10844283579     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/rcm.1735     Document Type: Article

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