Semi-automatic high-throughput determination of plasma protein binding using a 96-well plate filtrate assembly and fast liquid chromatography-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 795, Issue 2, 2003, Pages 187-194

  Fung, Eliza N ^a   Chen, Yung Hsiang ^a   Lau, Yau Yi ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

High throughput; Plasma protein binding; Proteins

Indexed keywords

LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PLASMA DIAGNOSTICS; PROTEINS;

PLASMA PROTEINS;

BIOMEDICAL ENGINEERING;

CHLORPROMAZINE; DESIPRAMINE; DIAZEPAM; IMIPRAMINE; LORAZEPAM; MIDAZOLAM; NICARDIPINE; NIFEDIPINE; OXAZEPAM; PLASMA PROTEIN; PROPRANOLOL; SILDENAFIL; VERAPAMIL;

ARTICLE; AUTOMATION; DRUG PROTEIN BINDING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PLASMA PROTEIN BINDING; PRIORITY JOURNAL; PROTEIN ANALYSIS; ROBOTICS; TANDEM MASS SPECTROMETRY; ULTRAFILTRATION;

EID: 0141537961     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1570-0232(03)00564-6     Document Type: Article

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