Changes in the enzymatic properties of CYP2D6 by the substitution of phenylalanine at position 120 by alanine

Journal of Health Science

Volumn 50, Issue 5, 2004, Pages 503-510

  Masuda, Kazufumi ^a   Hashimoto, Hiroki ^a   Tamagake, Keietsu ^a   Okuda, Yukie ^a   Tsuzuki, Daisuke ^a   Isobe, Takashi ^a   Hichiya, Hiroyuki ^a   Hanioka, Nobumitsu ^a   Yamamoto, Shigeo ^a   Narimatsu, Shizuo ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Alanine 120; Bunitrolol; Cytochrome P450 2D6; Debrisoquine; Phenylalanine 120

Indexed keywords

ALANINE; BUFURALOL; BUNITROLOL; CYTOCHROME P450 2D6; DEBRISOQUINE;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ENANTIOMER; ENZYME ACTIVITY; HYDROXYLATION; KINETICS; NONHUMAN; OXIDATION; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; SUBSTITUTION REACTION; WILD TYPE; YEAST;

SACCHAROMYCES CEREVISIAE;

EID: 10844251891     PISSN: 13449702     EISSN: None     Source Type: Journal    
DOI: 10.1248/jhs.50.503     Document Type: Article

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