Stereoselectivity in bunitrolol 4-hydroxylation in liver microsomes from marmosets and Japanese monkeys

Biological and Pharmaceutical Bulletin

Volumn 19, Issue 11, 1996, Pages 1429-1433

  Narimatsu, Shizuo ^a   Gotoh, Masumi ^a   Masubuchi, Yasuhiro ^a   Horie, Toshiharu ^a   Ohmori, Shigeru ^b   Kitada, Mitsukazu ^b   Kageyama, Takashi ^c   Asaoka, Kazuo ^c   Yamamoto, Ikuo ^d   Suzuki, Tokuji ^a  

^a CHIBA UNIVERSITY   (Japan)

^b CHIBA UNIVERSITY HOSPITAL   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d HOKURIKU UNIVERSITY   (Japan)

Author keywords

bunitrolol 4 hydroxylation; cytochrome P450 2D, 1A; human liver microsome; Japanese monkey; marmoset; stereoselectivity

Indexed keywords

4 HYDROXYBUNITROLOL; ALPHA NAPHTHOFLAVONE; BUNITROLOL; CYTOCHROME P450; QUINIDINE; QUININE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHIRALITY; DRUG HYDROXYLATION; DRUG METABOLISM; ENANTIOMER; LIVER MICROSOME; MARMOSET; MONKEY; NONHUMAN; STEREOCHEMISTRY;

EID: 10544229346     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.19.1429     Document Type: Article

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