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Volumn 27, Issue 6, 2004, Pages 467-477

Integration and modelling of pharmacokinetic and pharmacodynamic data to optimize dosage regimens in veterinary medicine

Author keywords

[No Author keywords available]

Indexed keywords

DRUG; NONSTEROID ANTIINFLAMMATORY AGENT;

EID: 10844242304     PISSN: 01407783     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2885.2004.00613.x     Document Type: Conference Paper
Times cited : (197)

References (38)
  • 1
    • 0036305707 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacokinetic/pharmacodynamic integration of marbofloxacin in calf serum, exudate and transudate
    • Aliabadi, F.S. & Lees, P. (2002) Pharmacokinetics and pharmacokinetic/ pharmacodynamic integration of marbofloxacin in calf serum, exudate and transudate. Journal of Veterinary Pharmacology and Therapeutics, 25, 161-174.
    • (2002) Journal of Veterinary Pharmacology and Therapeutics , vol.25 , pp. 161-174
    • Aliabadi, F.S.1    Lees, P.2
  • 2
    • 0347706219 scopus 로고    scopus 로고
    • Pharmacokinetics and PK-PD modelling of danofloxacin in camel serum and tissue cage fluids
    • Aliabadi, F.S. Ali, B.H., Landoni, M.F. & Lees, P. (2003) Pharmacokinetics and PK-PD modelling of danofloxacin in camel serum and tissue cage fluids. Veterinary Journal, 165, 104-118.
    • (2003) Veterinary Journal , vol.165 , pp. 104-118
    • Aliabadi, F.S.1    Ali, B.H.2    Landoni, M.F.3    Lees, P.4
  • 3
    • 0031915533 scopus 로고    scopus 로고
    • Rapid determination of oral pharmacokinetics and plasma free fraction using cocktail approaches: Methods and application
    • Allen, M.C., Shah, T.S. & Day, W.W. (1998) Rapid determination of oral pharmacokinetics and plasma free fraction using cocktail approaches: methods and application. Pharmaceutical Research, 15, 93-97.
    • (1998) Pharmaceutical Research , vol.15 , pp. 93-97
    • Allen, M.C.1    Shah, T.S.2    Day, W.W.3
  • 4
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
    • Anonymous (2001) Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clinical Pharmacology and Therapeutics, 69, 89-95.
    • (2001) Clinical Pharmacology and Therapeutics , vol.69 , pp. 89-95
  • 5
    • 0033730474 scopus 로고    scopus 로고
    • Optimizing the use of biomarkers, surrogate endpoints, and clinical endpoints for more efficient drug development
    • Colburn, W.A. (2000) Optimizing the use of biomarkers, surrogate endpoints, and clinical endpoints for more efficient drug development. Journal of Clinical Pharmacology, 40, 1419-1427.
    • (2000) Journal of Clinical Pharmacology , vol.40 , pp. 1419-1427
    • Colburn, W.A.1
  • 6
    • 0031952586 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodynamic parameters: Rationale for antibacterial dosing of mice and men
    • Craig, W.A. (1998) Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clinical Infectious Diseases, 26, 11-12.
    • (1998) Clinical Infectious Diseases , vol.26 , pp. 11-12
    • Craig, W.A.1
  • 8
    • 0002025584 scopus 로고
    • Parametric models of the time course of drug action
    • Eds van Boxtel, C.J., Holford, N.H.G. & Danhof, M. Elsevier Science Publishers, the Netherlands
    • Holford, N.H.G. (1992) Parametric models of the time course of drug action. In The in vivo Study of Drug Action. Eds van Boxtel, C.J., Holford, N.H.G. & Danhof, M. pp. 61-69. Elsevier Science Publishers, the Netherlands.
    • (1992) The in Vivo Study of Drug Action , pp. 61-69
    • Holford, N.H.G.1
  • 10
    • 0031873679 scopus 로고    scopus 로고
    • Plasma-pooling methods to increase throughput for in vivo pharmacokinetic screening
    • Hop, C.E., Wang, Z., Chen, Q. & Kwei, G. (1998) Plasma-pooling methods to increase throughput for in vivo pharmacokinetic screening. Journal of Pharmaceutical Sciences, 87, 901-903.
    • (1998) Journal of Pharmaceutical Sciences , vol.87 , pp. 901-903
    • Hop, C.E.1    Wang, Z.2    Chen, Q.3    Kwei, G.4
  • 11
    • 0028831358 scopus 로고
    • The importance of pharmacokinetic/pharmacodynamic surrogate markers to outcome. Focus on antibacterial agents
    • Hyatt, J.M., McKinnon, P.S., Zimmer, G.S. & Schentag, J.J. (1995) The importance of pharmacokinetic/pharmacodynamic surrogate markers to outcome. Focus on antibacterial agents. Clinical Pharmacokinetics, 28, 143-160.
    • (1995) Clinical Pharmacokinetics , vol.28 , pp. 143-160
    • Hyatt, J.M.1    McKinnon, P.S.2    Zimmer, G.S.3    Schentag, J.J.4
  • 12
    • 0029558785 scopus 로고
    • Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in calves
    • Landoni, M.F. & Lees, P. (1995) Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in calves. Chirality, 7, 586-597.
    • (1995) Chirality , vol.7 , pp. 586-597
    • Landoni, M.F.1    Lees, P.2
  • 13
    • 0029067035 scopus 로고
    • Determination of pharmacokinetics and pharmacodynamics of flunixin in calves by use of pharmacokinetic/pharmacodynamic modeling
    • Landoni, M.F., Cunningham, F.M. & Lees, P. (1995) Determination of pharmacokinetics and pharmacodynamics of flunixin in calves by use of pharmacokinetic/pharmacodynamic modeling. American Journal of Veterinary Research, 56, 786-794.
    • (1995) American Journal of Veterinary Research , vol.56 , pp. 786-794
    • Landoni, M.F.1    Cunningham, F.M.2    Lees, P.3
  • 14
  • 15
    • 0842284221 scopus 로고    scopus 로고
    • Pharmacology of drugs used to treat osteoarthritis in veterinary practice
    • Lees, P. (2003) Pharmacology of drugs used to treat osteoarthritis in veterinary practice. Inflammopharmacology, 11, 385-399.
    • (2003) Inflammopharmacology , vol.11 , pp. 385-399
    • Lees, P.1
  • 17
    • 0028439857 scopus 로고
    • Pharmacodynamics and pharmacokinetics of carprofen in the horse
    • Lees, P., McKellar, Q., May, S.A. & Ludwig, B. (1994) Pharmacodynamics and pharmacokinetics of carprofen in the horse. Equine Veterinary Journal, 26, 203-208.
    • (1994) Equine Veterinary Journal , vol.26 , pp. 203-208
    • Lees, P.1    McKellar, Q.2    May, S.A.3    Ludwig, B.4
  • 19
    • 10844269853 scopus 로고    scopus 로고
    • PK-PD integration and PK-PD modeling of non-steroidal anti-inflammatory drugs: Principles and applications in veterinary pharmacology
    • Lees, P., Giraudel, J., Landoni, M.F. & Toutain, P.L. (2004b) PK-PD integration and PK-PD modeling of non-steroidal anti-inflammatory drugs: principles and applications in veterinary pharmacology. Journal of Veterinary Pharmacology and Therapeutics, 27, 491-502.
    • (2004) Journal of Veterinary Pharmacology and Therapeutics , vol.27 , pp. 491-502
    • Lees, P.1    Giraudel, J.2    Landoni, M.F.3    Toutain, P.L.4
  • 20
    • 10844257324 scopus 로고    scopus 로고
    • PK-PD modeling: An alternative to dose titration studies for antimicrobial drug dosage selection
    • Lees, P., Aliabadi, F.S. & Toutain, P.L. (2004c) PK-PD modeling: an alternative to dose titration studies for antimicrobial drug dosage selection. Regulatory Affairs Journal, 15, 175-180.
    • (2004) Regulatory Affairs Journal , vol.15 , pp. 175-180
    • Lees, P.1    Aliabadi, F.S.2    Toutain, P.L.3
  • 21
    • 0025619681 scopus 로고
    • Comparative dose effect relations at several dosing intervals for beta-lactam, aminoglycoside and quinolone antibiotics against gram-negative bacilli in murine thigh-infection and pneumonitis models
    • Leggett, J.E., Ebert, S., Fantin, B. & Craig, W.A. (1991) Comparative dose effect relations at several dosing intervals for beta-lactam, aminoglycoside and quinolone antibiotics against gram-negative bacilli in murine thigh-infection and pneumonitis models. Scandinavian Journal of Infectious Diseases, Suppl. 74, 179-184.
    • (1991) Scandinavian Journal of Infectious Diseases , Issue.SUPPL. 74 , pp. 179-184
    • Leggett, J.E.1    Ebert, S.2    Fantin, B.3    Craig, W.A.4
  • 22
    • 10844289016 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodydnamic relationships of antimicrobial drugs used in veterinary medicine
    • McKellar, Q., Sanchez, S.F. & Jones, D.G. (2004) Pharmacokinetic/ pharmacodydnamic relationships of antimicrobial drugs used in veterinary medicine. Journal of Veterinary Pharmacology and Therapeutics, 27, 503-514.
    • (2004) Journal of Veterinary Pharmacology and Therapeutics , vol.27 , pp. 503-514
    • McKellar, Q.1    Sanchez, S.F.2    Jones, D.G.3
  • 23
    • 0021221208 scopus 로고
    • Association of aminoglycoside plasma levels with therapeutic outcome in gram-negative pneumonia
    • Moore, R.D., Smith, C.R. & Lietman, P.S. (1984) Association of aminoglycoside plasma levels with therapeutic outcome in gram-negative pneumonia. American Journal of Medicine, 77, 657-662.
    • (1984) American Journal of Medicine , vol.77 , pp. 657-662
    • Moore, R.D.1    Smith, C.R.2    Lietman, P.S.3
  • 24
    • 0345490945 scopus 로고    scopus 로고
    • XXXVIII. Update on terms and symbols in quantitative pharmacology
    • International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification
    • Neubig, R.R., Spedding, M., Kenakin, T. & Christopoulos, A. (2003) International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on Terms and Symbols in Quantitative Pharmacology. Pharmacological Reviews, 55, 597-606.
    • (2003) Pharmacological Reviews , vol.55 , pp. 597-606
    • Neubig, R.R.1    Spedding, M.2    Kenakin, T.3    Christopoulos, A.4
  • 25
    • 0024598288 scopus 로고
    • Clinical significance of antibiotic tissue penetration
    • Schentag, J.J. (1989) Clinical significance of antibiotic tissue penetration. Clinical Pharmacokinetics, 16 (Suppl. 1), 25-31.
    • (1989) Clinical Pharmacokinetics , vol.16 , Issue.SUPPL. 1 , pp. 25-31
    • Schentag, J.J.1
  • 26
    • 0021867438 scopus 로고
    • Dual individualization: Antibiotic dosage calculation from the integration of in-vitro pharmacodynamics and in-vivo pharmacokinetics
    • Schentag, J.J., Swanson, D.J. & Smith, I.L. (1985) Dual individualization: antibiotic dosage calculation from the integration of in-vitro pharmacodynamics and in-vivo pharmacokinetics. Journal of Antimicrobial Chemotherapy, 15 (Suppl. A) 47-57.
    • (1985) Journal of Antimicrobial Chemotherapy , vol.15 , Issue.SUPPL. A , pp. 47-57
    • Schentag, J.J.1    Swanson, D.J.2    Smith, I.L.3
  • 27
    • 0026087226 scopus 로고
    • A simulation study comparing designs for dose ranging
    • Sheiner, L.B., Hashimoto, Y. & Beal, S.L. (1991) A simulation study comparing designs for dose ranging. Statistics in Medicine, 10, 303-321.
    • (1991) Statistics in Medicine , vol.10 , pp. 303-321
    • Sheiner, L.B.1    Hashimoto, Y.2    Beal, S.L.3
  • 28
    • 85046914278 scopus 로고    scopus 로고
    • Pharmacokinetics/pharmacodynamics integration in drug development and dosage regimen optimization for veterinary medicine
    • Toutain, P.L. (2002) Pharmacokinetics/pharmacodynamics integration in drug development and dosage regimen optimization for veterinary medicine. AAPS Pharmaceutical Sciences, 4: http://www.aapspharmsci. org/ps0404/ps040438/ ps040438.pdf [accessed 1 December 2004].
    • (2002) AAPS Pharmaceutical Sciences , pp. 4
    • Toutain, P.L.1
  • 29
    • 0842321035 scopus 로고    scopus 로고
    • Pharmacokinetics/pharmacodynamics integration in dosage regimen optimization for veterinary medicine
    • 9th International Congress of the European Association for Veterinary Pharmacology and Toxicology. Lisbon, Portugal, July 13-18, 2003. Eds Fontes, M.E. & Lees, P.
    • Toutain, P.L. (2003) Pharmacokinetics/pharmacodynamics integration in dosage regimen optimization for veterinary medicine. In: 9th International Congress of the European Association for Veterinary Pharmacology and Toxicology. Lisbon, Portugal, July 13-18, 2003. Eds Fontes, M.E. & Lees, P. Journal of Veterinary Pharmacology and Therapeutics, 26 (Suppl. 1), 1-8.
    • (2003) Journal of Veterinary Pharmacology and Therapeutics , vol.26 , Issue.SUPPL. 1 , pp. 1-8
    • Toutain, P.L.1
  • 31
    • 0036560072 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodynamic approach to assess irrelevant plasma or urine drug concentrations in postcompetition samples for drug control in the horse
    • Toutain, P.L. & Lassourd, V. (2002a) Pharmacokinetic/pharmacodynamic approach to assess irrelevant plasma or urine drug concentrations in postcompetition samples for drug control in the horse. Equine Veterinary Journal, 34, 242-249.
    • (2002) Equine Veterinary Journal , vol.34 , pp. 242-249
    • Toutain, P.L.1    Lassourd, V.2
  • 32
    • 10844225196 scopus 로고    scopus 로고
    • Pharmacokinetics/pharmacodynamic assessment of irrelevant drug concentrations in horse plasma or urine for a selection of drugs
    • Eds Hill, D.W. & Hill, W.T. RandW Publication Ltd, Orlando, FL, USA
    • Toutain, P.L. & Lassourd, V. (2002b) Pharmacokinetics/pharmacodynamic assessment of irrelevant drug concentrations in horse plasma or urine for a selection of drugs. In 14th International Conference of Racing Analysts and Veterinarians. Eds Hill, D.W. & Hill, W.T. pp. 19-27. RandW Publication Ltd, Orlando, FL, USA.
    • (2002) 14th International Conference of Racing Analysts and Veterinarians , pp. 19-27
    • Toutain, P.L.1    Lassourd, V.2
  • 33
    • 8344270368 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacokinetic/pharmacodynamic relationships for angiotensin-converting-enzyme (ACE) inhibitors
    • Toutain, P.L. & Lefebvre, H.P. (2004) Pharmacokinetics and pharmacokinetic/pharmacodynamic relationships for angiotensin-converting-enzyme (ACE) inhibitors. Journal of Veterinary Pharmacology and Therapeutics, 27, 515-525.
    • (2004) Journal of Veterinary Pharmacology and Therapeutics , vol.27 , pp. 515-525
    • Toutain, P.L.1    Lefebvre, H.P.2
  • 34
    • 0028598305 scopus 로고
    • Plasma concentrations and therapeutic efficacy of phenylbutazone and flunixin meglumine in the horse: Pharmacokinetlc/pharmacodynamic modelling
    • Toutain, P.L., Autefage, A., Legrand, C. & Alvinerie, M. (1994) Plasma concentrations and therapeutic efficacy of phenylbutazone and flunixin meglumine in the horse: pharmacokinetlc/pharmacodynamic modelling. Journal of Veterinary Pharmacology and Therapeutics, 17, 459-469.
    • (1994) Journal of Veterinary Pharmacology and Therapeutics , vol.17 , pp. 459-469
    • Toutain, P.L.1    Autefage, A.2    Legrand, C.3    Alvinerie, M.4
  • 35
    • 0034092790 scopus 로고    scopus 로고
    • Benazeprilat disposition and effect in dogs revisited with a pharmacokinetic/pharmacodynamic modeling approach
    • Toutain, P.L., Lefebvre, H.P. & King, J.N. (2000) Benazeprilat disposition and effect in dogs revisited with a pharmacokinetic/pharmacodynamic modeling approach. Journal of Pharmacology and Experimental Therapeutics, 292, 1087-1093.
    • (2000) Journal of Pharmacology and Experimental Therapeutics , vol.292 , pp. 1087-1093
    • Toutain, P.L.1    Lefebvre, H.P.2    King, J.N.3
  • 36
    • 0035029513 scopus 로고    scopus 로고
    • A pharmacokinetic/pharmacodynamic approach vs. a dose titration for the determination of a dosage regimen: The case of nimesulide, a Cox-2 selective nonsteroidal anti-inflammatory drug in the dog
    • Toutain, P.L., Cester, C.C., Haak, T. & Laroute, V. (2001) A pharmacokinetic/pharmacodynamic approach vs. a dose titration for the determination of a dosage regimen: the case of nimesulide, a Cox-2 selective nonsteroidal anti-inflammatory drug in the dog. Journal of Veterinary Pharmacology and Therapeutics, 24, 43-55.
    • (2001) Journal of Veterinary Pharmacology and Therapeutics , vol.24 , pp. 43-55
    • Toutain, P.L.1    Cester, C.C.2    Haak, T.3    Laroute, V.4
  • 37
    • 0036799286 scopus 로고    scopus 로고
    • The pharmacokinetic-pharmacodynamic approach to a rational dosage regimen for antibiotics
    • Toutain, P.L., del Castillo, J.R.E. & Bousquet-Mélou, A. (2002) The pharmacokinetic-pharmacodynamic approach to a rational dosage regimen for antibiotics. Research in Veterinary Science, 73, 105-114.
    • (2002) Research in Veterinary Science , vol.73 , pp. 105-114
    • Toutain, P.L.1    Del Castillo, J.R.E.2    Bousquet-Mélou, A.3
  • 38
    • 0033594911 scopus 로고    scopus 로고
    • Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis
    • Warner, T.D., Giuliano, F., Vojnovic, I., Bukasa, A., Mitchell, J.A. & Vane, J.R. (1999) Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proceedings of the National Academic of Sciences, 96, 7563-7568.
    • (1999) Proceedings of the National Academic of Sciences , vol.96 , pp. 7563-7568
    • Warner, T.D.1    Giuliano, F.2    Vojnovic, I.3    Bukasa, A.4    Mitchell, J.A.5    Vane, J.R.6


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