High-Throughput Detection of Glutathione S-Transferase Polymorphic Alleles in a Pediatric Cancer Population

Cancer Epidemiology Biomarkers and Prevention

Volumn 13, Issue 2, 2004, Pages 304-313

  Barnette, Phillip ^a   Scholl, Rebecca ^b   Blandford, Mary ^a   Ballard, Linda ^b   Tsodikov, Alexander ^b   Magee, Jalene ^b   Williams, Susana ^b   Robertson, Margaret ^b   Ali Osman, Francis ^c   Lemons, Richard ^a   Keller, Charles ^a,d  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d PRIMARY CHILDREN'S MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; GLUTATHIONE TRANSFERASE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ALLELE; ARTICLE; BRAIN TUMOR; CANCER RISK; CHILD; CHILDHOOD CANCER; COST EFFECTIVENESS ANALYSIS; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; INFANT; MAJOR CLINICAL STUDY; OSTEOSARCOMA; PHARMACOGENETICS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

ANTINEOPLASTIC AGENTS; CHILD; CHILD, PRESCHOOL; COST CONTROL; DNA PRIMERS; DNA, NEOPLASM; FEMALE; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; MALE; NEOPLASMS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 10744233323     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-03-0178     Document Type: Article

References (44)

1. Krajinovic, M., Labuda, D., Richer, C., Karimi, S., and Sinnett, D. Susceptibility to childhood acute lymphoblastic leukemia: influence of CYP1A1, CYP2D6, GSTM1, and GSTT1 genetic polymorphisms. Blood, 93: 1496-1501, 1999.
2. Jahnke, V., Matthias, C., Fryer, A., and Strange, R. Glutathione S-transferase and cytochrome P-450 polymorphism as risk factors for squamous cell carcinoma of the larynx. Am. J. Surg., 172: 671-673, 1996.
3. Katoh, T., et al. Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) genetic polymorphism and susceptibility to gastric and colorectal adenocarcinoma. Carcinogenesis (Lond.), 17: 1855-1859, 1996.
4. Zhong, S., Wyllie, A. H., Barnes, D., Wolf, C. R., and Spurr, N. K. Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast, and colon cancer. Carcinogenesis (Lond.), 14: 1821-1824, 1993.
5. Goto, I., Yoneda, S., Yamamoto, M., and Kawajiri, K. Prognostic significance of germ-line polymorphisms of the CYP1A1 and glutathione S-transferase genes in patients with non-small cell lung cancer. Cancer Res., 56: 3725-3730, 1996.
6. Hirvonen, A., Husgafvel-Pursiaen, K., Anttila, S., and Vainio, H. The GSTM1 null genotype as a potential risk modifier for squamous cell carcinoma of the lung. Carcinogenesis (Lond.), 14: 1479-1481, 1993.
7. Hirvonen, A., et al. Inherited GSTM1 and NAT2 defects as concurrent risk modifiers in asbestos-related human malignant mesothelioma. Cancer Res., 55: 2981-2983, 1995.
8. Fryer, A. A., et al. The glutathione S-transferases: polymerase chain reaction studies on the frequency of the GSTM1 0 genotype in patients with pituitary adenomas. Carcinogenesis (Lond.), 14: 563-566, 1993.
9. Helzlsouer, K. J., et al. Association between glutathione S-transferase M1, P1, and T1 genetic polymorphisms and development of breast cancer. J. Natl. Cancer Inst. (Bethesda), 90: 512-518, 1998.
10. Brockmoller, J., Kerb, R., Drakoulis, N., Staffeldt, B., and Roots, I. Glutathione S-transferase M1 and its variants A and B as host factors of bladder cancer susceptibility: a case-control study. Cancer Res., 54: 4103-4111, 1994.
11. Anwar, W. A., Abdel-Rahman, S. Z., El-Zein, R. A., Mostafa, H. M., and Au, W. W. Genetic polymorphism of GSTM1, CYP2E1 and CYP2D6 in Egyptian bladder cancer patients. Carcinogenesis (Lond.), 17: 1923-1929, 1996.
12. Yengi, L., et al. Polymorphisms at the glutathione S-transferase locus GSTM3: interactions with cytochrome P450 and glutathione S-transferase genotypes as risk factors for multiple cutaneous basal cell carcinoma. Cancer Res., 56: 1974-1979, 1996.
13. Heagerty, A. H. et al. Glutathione S-transferase GSTM1 phenotypes and protection against cutaneous tumors. Lancet, 343: 266-269, 1994.
14. Volm, M., Zintl, F., Elder, L., and Sauerbrey, A. Prognostic value of protein kinase C, proto-oncogene products and resistance-related proteins in newly diagnosed childhood acute lymphoblastic leukemia. Med. Pediatr. Oncol., 28: 117-126, 1997.
15. Sauerbrey, A., Zintl, F., and Volm, M. P-Glycoprotein and glutathione S-transferase π in childhood acute lymphoblastic leukaemia. Br. J. Cancer, 70: 1144-1149, 1994.
16. Elexpuru-Camiruaga, J. et al. Susceptibility to astrocytoma and meningioma: influence of allelism at glutathione S-transferase (GSTT1 and GSTM1) and cytochrome P-450 (CYP2D6) loci. Cancer Res., 55: 4237-4239, 1995.
17. Lear, J. T. et al. Multiple cutaneous basal cell carcinomas: glutathione S-transferase (GSTM1, GSTT1) and cytochrome P450 (CYP2D6, CYP1A1) polymorphisms influence tumour numbers and accrual. Carcinogenesis (Lond.), 17: 1891-1896, 1996.
18. Chen, C-L. et al. Higher frequency of glutathione S-transferase deletions in black children with acute lymphoblastic lymphoma. Blood, 89: 1701-1707, 1997.
19. Bruning, T. et al. Influence of polymorphisms of GSTM1 and GSTT1 for risk of renal cell cancer in workers with long-term high occupational exposure to trichloroethylene. Arch. Toxicol., 71: 596-599, 1997.
20. Kristensen, V. et al. Single tube multiplex polymerase chain reaction genotype analysis of STM1, GSTT1, and GSTP1: relationship of genotypes to TP53 tumor status and clinicopathological variables in breast cancer patients. Pharmacogenetics, 8: 441-447, 1998.
21. Howells, R. E. et al. Association of glutathione S-transferase GSTM1 and GSTT1 null genotypes with clinical outcomes in epithelial ovarian cancer. Clin. Cancer Res., 4: 2439-2445, 1998.
22. Green, J. A., Robertson, L. J., and Clark, A. H. Glutathione S-transferase expression in benign and malignant ovarian tumors. Br. J. Cancer, 68: 235-239, 1993.
23. Ali-Osman, F., Brunner, J., Kutluk, T., and Hess, K. Prognostic significance of glutathione S-transferase π expression and subcellular localization in human glioma. Clin. Cancer Res., 3: 2253-2261, 1997.
24. Monden, N. et al. Prognostic significance of the expressions of metallothionen, glutathione S-transferase π, and P-glycoprotein in curatively resected gastric cancer. Oncology, 54: 391-399, 1997.
25. Bergh, J. Time for integration of predictive factors for selection of breast cancer patients who need postoperative radiation therapy? J. Natl. Cancer Inst. (Bethesda), 89: 60-62, 1997.
26. Silvestrini, R. et al. Expression of p53, glutathione S-transferase π, and Bcl-2 proteins and benefit from adjuvant radiotherapy in breast cancer. J. Natl. Cancer Inst. (Bethesda), 89: 639-645, 1997.
27. Gilbert, L. et al. A pilot study of π-class glutathione S-transferase expression in breast cancer: correlation with estrogen receptor expression and prognosis in node-negative breast cancer. J. Clin. Oncol., 11: 49-58, 1993.
28. Yokoyama, Y., Sagara, M., Sato, S., and Saito, Y. Value of glutathione S-transferase π and the oncogene products c-Jun, c-Fos, c-H-Ras, and c-Myc as a prognostic indicator in endometrial carcinomas. Gynecol. Oncol., 68: 280-287, 1998.
29. Hall, A. G. et al. Glutathione S-transferases in bone marrow metastases of disseminated neuroblastoma. J. Clin. Pathol. (Lond.), 47: 468-469, 1994.
30. Lum, A., and LeMarchand, L. A simple mouthwash method for obtaining genomic DNA in molecular epidemiological studies. Cancer Epidemiol. Biomark. Prev., 7: 719-724, 1998.
31. Kerb, R. et al. Influence of GSTT1 and GSTM1 Genotypes on Sunburn Sensitivity. Am. J. Pharmacogenomics, 2: 147-154, 2002.
32. Fryer, A., Zhao, L., Alldersea, J., Pearson, W. R., and Strange, R. C. Use of site-directed mutagenesis of allele-specific PCR primers to identify the GSTM1A, GSTM1B, GSTM1A, B and GSTM1 null polymorphisms at the glutathione S-transferase, GSTM1 locus. Biochem. J., 295: 313-315, 1993.
33. Board, P., Harris, M., Flanagan, J., Langton, L., and Coggan, M. Genetic heterogeneity of the structure and function of GSTT2 and PSTP1. Chem. Biol. Interact., 111-112: 83-89, 1998.
34. Harries, L., Stubbins, M., Forman, D., Howard, G., and Wolf, R. Identification of genetic polymorphisms at the glutathione S-transferase π locus and association with susceptibility to bladder, testicular and prostate cancer. Carcinogenesis (Lond.), 641-644, 1997.
35. Alves, S., Amorim, A., Ferreira, F., Norton, L., and Prata, M. J. The GSTM1 and GSTT1 genetic polymorphisms and susceptibility to acute lymphoblastic leukemia in children from north Portugal. Leukemia (Baltimore), 16: 1565-1567, 2002.
36. Casanova, M., Bell, D. A., and Heck, H. d. A. Dichloromethane metabolism to formaldehyde and reaction of formaldehyde with nucleic acids in hepatocytes of rodents and humans with and without glutathione S-transferase T1 and M1 genes. Fundam. Appl. Toxicol., 37: 168-180, 1997.
37. Davies, S. M. et al. Glutathione S-transferase genotypes, genetic susceptibility, and outcome of therapy in childhood acute lymphoblastic leukemia. Blood, 100: 67-71, 2002.
38. Infante-Rivard, C., Amre, D., and Sinnett, D. GSTT1 and CYP2E1 polymorphisms and trihalomethanes in drinking water: effect on childhood leukemia. Environ. Health Perspect., 110: 591-593, 2002.
39. Inskip, A. et al. Identification of polymorphism at the glutathione S-transferase, GSTM3 locus: evidence for linkage with GSTM1*A. Biochem. J., 312: 713-716, 1995.
40. Ali-Osman, F., Akande, O., Antoun, G., Mao, J-X., and Buolamwini, J. Molecular cloning, characterization, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase π gene variants. The J. Biol. Chem., 272: 10004-10012, 1997.
41. Watson, M. A., Stewart, R. K., Smith, G. B. J., Massey, T. E., and Bell, D. A. Human glutathione S-transferase P1 polymorphisms: relationship to lung tissue enzyme activity and population frequency distribution. Carcinogenesis (Lond.), 19: 275-280, 1998.
42. Pemble, S. et al. Human glutathione S-transferase θ (GSTT1): cDNA cloning and characterization of a genetic polymorphism. Biochem. J., 300: 271-276, 1994.
43. Brownstein, M. J., Carpten, J. D., and Smith, J. R. Modulation of non-templated nucleotide addition by Taq DNA polymerase: primer modifications that facilitate genotyping. Biotechniques, 20: 1004-1010, 106: 1008-1010, 1996.
44. Magnuson, V. L. et al. Substrate nucleotide-determined non-templated addition of adenine by Taq DNA polymerase: implications for PCR-based genotyping and cloning. Biotechniques, 21: 700-709, 1996.