Polymorphism at the glutathione S-transferase locus GSTM3: Interactions with cytochrome P450 and glutathione S-transferase genotypes as risk factors for multiple cutaneous basal cell carcinoma

Cancer Research

Volumn 56, Issue 9, 1996, Pages 1974-1977

  Yengi, Lilian ^a   Inskip, Avis ^a   Gilford, Janice ^a   Alldersea, Julie ^a   Bailey, Lisa ^a   Smith, Andrew ^b   Lear, John T ^b   Heagerty, Adrian H ^b   Bowers, Bill ^c   Hand, Philip ^a   Hayes, John D ^d   Jones, Peter W ^a   Strange, Richard C ^a   Fryer, Anthony A ^a  

^a KEELE UNIVERSITY   (United Kingdom)

^b UNIVERSITY HOSPITAL OF NORTH STAFFORDSHIRE   (United Kingdom)

^c ROYAL CORNWALL HOSPITAL   (United Kingdom)

^d UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BASAL CELL CARCINOMA; CANCER RISK; CONTROLLED STUDY; FEMALE; GENE LOCUS; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RISK FACTOR; SEX DIFFERENCE; SKIN CARCINOGENESIS;

AGED; ALLELES; CARCINOMA, BASAL CELL; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEOPLASMS, MULTIPLE PRIMARY; POLYMORPHISM, GENETIC; RISK FACTORS; SKIN NEOPLASMS;

EID: 9244246804     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Strange, R. C. Glutathione S-transferases and cancer susceptibility. In: Proceedings 1995 International ISSX-Workshop on GIutathione S-transferases Taylor and Francis, in press, 1996.
2. Smith, G., Stanley, L. A., Sim, E., Strange, R. C., and Wolf, C. R. Metabolic polymorphisms and cancer susceptibility. Cancer Surv., 25: 27-65, 1996.
3. Hayes, J. D., and Pulford, D. J. The glutathione S-transferase supergene family Regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit. Rev. Biochem. Mol. Biol., 30. 445-600, 1995.
4. Heagerty, A. H. M., Fitzgerald, D., Smith, A , Bowers, B., Jones, P., Fryer, A., Zhao, L , Alldersea, J., and Strange, R C. Glutathione S-transferase GSTM1 phenotypes and protection against cutaneous malignancy. Lancet, 343 266-268, 1994.
5. Hussey, A. J , and Hayes, J. D. H. Human μ-class glutathione S-transferases present in liver, skeletal muscle and testicular tissue. Biochim. Biophys. Acta, 1203: 131-141, 1993
6. Pearson, W. R., Vorachek, W., Xu, S., Berger, R., Hart, I., Vannais, D., Patterson, D Identification of class-μ glutathione S-transferase genes GSTM1-GSTM5 on chromosome 1p13 Am. J. Hum Genet , 53. 220-233, 1993
7. Antilla, S., Luostarinen, L., Hirvonen, A., Elovaara, E., Katjalainen, A., Nurminen, T., Hayes, J D , Vainio, H., and Ketterer, B. Pulmonary expression of glutathione S-transferase M3 in lung cancer patients, association with GSTM1 polymorphism, smoking and asbestos exposure. Cancer Res., 55: 3305-3309, 1995.
8. Inskip, A., Elexperu-Camiruaga, J., Buxton, N , Dias, P. S., MacIntosh, J., Campbell, D., Jones, P W., Yengi, L., Talbot, A., Strange, R. C., and Fryer, A. A. Identification of polymorphism at the glutathione-S-transferase, GSTM3 locus: evidence for linkage with GSTM1*A Biochem. J., 312 713-716, 1995
9. Flanagan, J R. Autologous stimulation of YYI transcription factor expression: role of an insulin-like growth factor. Cell Growth Differ., 6: 85-190, 1995.
10. Heagerty, A., Smith, A., English, J., Lear, J., Perkins, W., Bowers, B., Jones, P. W., Gilford, J , Alldersea, J., Fryer, A. A., and Strange, R. C. Susceptibility to multiple cutaneous basal cell carcinomas: significant interactions between glutathione S-transferase GSTM1 genotypes, skin type and male gender. Br. J. Cancer 73: 44-48, 1996.
11. Lear, J. T., Heagerty, A. H. M, Smith, A., Bowers, B., Payne, C. R., Smith, C. A , Jones, P. W., Gilford, J., Yengi, L., Alldersea, J , Fryer, A. A., and Strange, R. C. Multiple cutaneous basal cell carcinomas: glutathione S-transferase (GSTM1, GSTT1) and cytochrome P450 (CYP2D6, CYP1A1) polymorphisms influence tumor numbers and accrual In: Photocarcinogenesis: Mechanisms, Models and Human Health Implications. Washington DC, in press, 1996.
12. Hiley, C., Oner, M., Bell, J., Strange, R., and Keeling, J. Immunocytochemical studies of the distribution of a and π isoforms of glutathione S-transferase in cystic renal diseases. Pediatr. Pathol 14: 497-504, 1994.
13. Cantlay, A. M , Lamb, D , Gillooly, M , Norrman, J., Mormon, D., Smith, C A D., and Harrison, D. J. Association between the CYP1A1 gene polymorphism and susceptibility to emphysema and lung cancer. J Clin. Pathol. Mol. Pathol., 48: M210-M214, 1995
14. Kricker, A , Armstrong, B K., Jones, M E., and Burton, R. C. Health, solar UV radiation and environmental change, pp. 52-61. IARC Technical Report No. 13, Lyon, France: IARC, 1993.
15. Karagas, M. R., and Greenberg, E R. Unresolved issues in the epidemiology of basal cell and squamous cell skin cancer. In: H Mukhtar (ed.). Skin Cancer. Mechanisms and Human Relevance, pp 79-86. Boca Raton, FL: CRC Press, 1995.
16. Ollier, W., Davies, E , Snowden, N., Alldersea, J., Fryer, A. A , and Strange, R C Homozygosity for null alleles of glutathione S-transferase GSTM1 is associated with the Ro+/La-autoantibody profile in SLE. Arthritis Rheum., in press, 1996.
17. Gonzalez, F. Role of cytochrome P450 1A1 in skin cancer. In: H Mukhtar (ed ), Skin Cancer: Mechanisms and Human Relevance, pp. 89-97. Boca Raton, FL: CRC Press, 1995
18. Nebert, D. W Drug-metabolizing enzymes in ligand-modulated transcription. Biochem. Pharmacol., 47: 25-37, 1994
19. Vaury, C , Lainé, R , Nogulez, P., de Coppei, P., Jaulin, C , Praz, F., Pompon, D , and Amor-Guéret, M. Human glutamione S-transferase M1 null genotype is associated with a high inducibility of cytochrome P450 1A1 gene transcription. Cancer Res., 55: 5520-5523, 1995.
20. Elexpuru-Camiruaga, J., Buxton, N., Kandula, V., Dias, V. S., Campbell, D., McIntosh, J., Broome, J., Jones, P., Inskip, A., Alldersea, J , Fryer, A. A , and Strange, R. C. Susceptibility 10 astrocytoma and meningioma: influence of allelism at glutathione S-transferase (GSTT1 and GSTM1) and cytochrome P450 (CYP2D6) loci Cancer Res., 55: 4237-4239, 1995