New Model for Analysis of Dynamic Contrast-Enhanced MRI Data Distinguishes Metastatic from Nonmetastatic Transplanted Rodent Prostate Tumors

Magnetic Resonance in Medicine

Volumn 51, Issue 3, 2004, Pages 487-494

  Fan, Xiaobing ^a   Medved, Milica ^a   River, Jonathan N ^a   Zamora, Marta ^a   Corot, Claire ^b   Robert, Philippe ^b   Bourrinet, Philippe ^b   Lipton, Martin ^a   Culp, Rita M ^a   Karczmar, Gregory S ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b Laboratoire Guerbet   (France)

Author keywords

Angiogenesis; Dynamic contrast enhanced MRI; Gd DTPA; P792; Prostate cancer

Indexed keywords

DISEASES; MAGNETIC RESONANCE IMAGING; MAMMALS; MOLECULAR WEIGHT; MUSCLE; UROLOGY;

ANGIOGENESIS; DYNAMIC CONTRAST ENHANCED MRI; GD-DTPA; P792; PROSTATE CANCERS;

TUMORS;

CONTRAST MEDIUM; GADOLINIUM PENTETATE; GADOMELITOL; PENTETIC ACID; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL MODEL; ARTICLE; BENIGN TUMOR; CANCER TRANSPLANTATION; COMPARTMENT MODEL; CONTRAST ENHANCEMENT; CONTROLLED STUDY; CURVE FITTING; DATA ANALYSIS; DRUG CONCENTRATIN TIME CURVE; DRUG ELIMINATION; DRUG TISSUE LEVEL; DRUG UPTAKE; DRUG WASHOUT RATE; DYNAMIC CONTRAST ENHANCED NUCLEAR MAGNETIC RESONANCE IMAGING; EXPERIMENTAL NEOPLASM; INTERMETHOD COMPARISON; MALE; MATHEMATICAL MODEL; METASTASIS; MICROENVIRONMENT; MODEL; MOLECULAR WEIGHT; MUSCLE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PROSTATE TUMOR; RAT; TUMOR BLOOD FLOW;

EID: 10744233010     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.10737     Document Type: Article

References (30)

1. Hulka CA, Edmister WB, Smith BL, Tan L, Sgroi DC, Campbell T, Kopans DB, Weisskoff RM. Dynamic echo-planar imaging of the breast: experience in diagnosing breast carcinoma and correlation with tumor angiogenesis. Radiology 1997;205:837-842.
2. Nunes LW, Schnall MD, Siegelman ES, Langlotz CP, Orel SG, Sullivan D, Muenz LA, Reynolds CA, Torosian MH. Diagnostic performance characteristics of architectural features revealed by high spatial-resolution MR imaging of the breast. AJR Am J Roentgenol 1997;169:409-415.
3. Daniel BL, Yen YF, Glover GH, Ikeda DM, Birdwell RL, Sawyer-Glover AM, Black JW, Plevritis SK, Jeffrey SS, Herfkens RJ. Breast disease: dynamic spiral MR imaging. Radiology 1998;209:499-509.
4. Kuhl CK, Mielcareck P, Klaschik S, Leutner C, Wardelmann E, Gieseke J, Schild HH. Dynamic breast MR imaging: are signal intensity time course data useful for differential diagnosis of enhancing lesions? Radiology 1999;211:101-110.
5. Orel SG. Differentiating benign from malignant enhancing lesions identified at MR imaging of the breast: are time-signal intensity curves an accurate predictor? Radiology 1999;211:5-7.
6. Weinstein D, Strano S, Cohen P, Fields S, Gomori JM, Degani H. Breast fibroadenoma: mapping of pathophysiologic features with three-time-point, contrast-enhanced MR imaging - pilot study. Radiology 1999; 210:233-240.
7. Kety SS. Theory and application of the exchange of inert gas at the lungs and tissues. Pharmacol Rev 1951;3:1-41.
8. Tofts PS, Kermode AG. Measurement of the blood-brain barrier permeability and leakage space using dynamic MR imaging. I. Fundamental concepts. Magn Reson Med 1991;17:357-367.
9. Shames DM, Kuwatsuru R, Vexler V, Muhler A, Brasch RC. Measurement of capillary permeability to macromolecules by dynamic magnetic resonance imaging: a quantitative noninvasive technique. Magn Reson Med 1993;29:616-622.
10. Port RE, Knopp MV, Hoffmann U, Milker-Zabel S, Brix G. Multicompartment analysis of gadolinium chelate kinetics: blood-tissue exchange in mammary tumors as monitored by dynamic MR imaging. J Magn Reson Imaging 1999;10:233-241.
11. Tennant TR, Kim H, Sokoloff M, Rinker-Schaeffer CW. The Dunning model. Prostate 2000;43:295-302.
12. Fan X, River JN, Zamora M, Tarlo K, Kellar K, Rinker-Schaeffer C, Karczmar GS. Differentiation of nonmetastatic and metastatic rodent prostate tumors with high spectral and spatial resolution MRI. Magn Reson Med 2001;45:1046-1055.
13. Port M, Corot C, Rousseaux O, Raynal I, Devoldere L, Idee JM, Dencausse A, Le Greneur S, Simonot C, Meyer D. P792: a rapid clearance blood pool agent for magnetic resonance imaging: preliminary results. MAGMA 2001;12:121-127.
14. Port M, Corot C, Raynal I, Idee JM, Dencausse A, Lancelot E, Meyer D, Bonnemain B, Lautrou J. Physicochemical and biological evaluation of P792, a rapid-clearance blood-pool agent for magnetic resonance imaging. Invest Radiol 2001;36:445-454.
15. Ogan MD, Schmiedl U, Moseley ME, Grodd W, Paajanen H, Brasch RC. Albumin labeled with Gd-DTPA. An intravascular contrast-enhancing agent for magnetic resonance blood pool imaging: preparation and characterization. Invest Radiol 1987;22:665-671.
16. Reichenbach JR, Hacklander T, Harth T, Hofer M, Rassek M, Modder U. 1H T1 and T2 measurements of the MR imaging contrast agents Gd-DTPA and Gd-DTPA BMA at 1.5T. Eur Radiol 1997;7:264-274.
17. Ruehm SG, Christina H, Violas X, Corot C, Debatin JF. MR angiography with a new rapid-clearance blood pool agent: initial experience in rabbits. Magn Reson Med 2002;48:844-851.
18. Medved M, MacEneany P, Karczmar GS, Kindler H, Gajewski T, Vokes E, O'Connor E, Stadler W. Contrast agent dynamics as an early marker of antiangiogenic agent action. In: Proceedings of the 10th Annual Meeting of ISMRM, Honolulu, 2002. p 2099.
19. Bydder GM, Hajnal JV, Young IR. Use of the inversion recovery pulse sequence. In: Stark D, Bradley W, editors. Magnetic resonance imaging. Vol. I, 3rd ed. St. Louis: William G. Mosby; 1999. p 69-86.
20. Kovar DA, Lewis M, Karczmar GS. A new method for imaging perfusion and contrast extraction fraction: input functions derived from reference tissues. J Magn Reson Imaging 1998;8:1126-1134.
21. Tofts PS, Brix G, Buckley DL, Evelhoch JL, Henderson E, Knopp MV, Larsson HB, Lee TY, Mayr NA, Parker GJ, Port RE, Taylor J, Weisskoff RM. Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols. J Magn Reson Imaging 1999;10:223-232.
22. Corot C, Port M, Raynal I, Dencausse A, Schaefer M, Rousseaux O, Simonot C, Devoldere L, Lin J, Foulon M, Bourrinet P, Bonnemain B, Meyer D. Physical, chemical, and biological evaluations of P760: a new gadolinium complex characterized by a low rate of interstitial diffusion. J Magn Reson Imaging 2000;11:182-191.
23. Press WH, Teukolsky SA, Vetterling WT, Flannery BP. Numerical recipes in C: the art of scientific computing. Oxford: Cambridge University Press; 1997.
24. Yu H, Su MY, Wang Z, Nalcioglu O. A longitudinal study of radiation-induced changes in tumor vasculature by contrast-enhanced magnetic resonance imaging. Radiat Res 2002;158:152-158.
25. Demsar F, Roberts TP, Schwickert HC, Shames DM, van Dijke CF, Mann JS, Saeed M, Brasch RC. A MRI spatial mapping technique for microvascular permeability and tissue blood volume based on macromolecular contrast agent distribution. Magn Reson Med 1997;37:236-242.
26. Turetschek K, Floyd E, Shames DM, Roberts TP, Preda A, Novikov V, Corot C, Carter WO, Brasch RC. Assessment of a rapid clearance blood pool MR contrast medium (P792) for assays of microvascular characteristics in experimental breast tumors with correlations to histopathology. Magn Reson Med 2001;45:880-886.
27. Weidner N. Intratumor microvessel density as a prognostic factor in cancer. Am J Pathol 1995;147:9-19.
28. van Dijke CF, Peterfy CG, Brasch RC, Lang P, Roberts TP, Shames DM, Kneeland JB, Lu Y, Mann JS, Kapila SD, Genant HK. MR imaging of the arthritic rabbit knee joint using albumin-(Gd-DTPA)30 with correlation to histopathology. Magn Reson Imaging 1999;17:237-245.
29. van Dijke CF, Mann JS, Rosenau W, Wendland MF, Roberts TP, Roberts HC, Demsar F, Brasch RC. Comparison of MR contrast-enhancing properties of albumin-(biotin)10-(gadopentetate)25, a macromolecular MR blood pool contrast agent, and its microscopic distribution. Acad Radiol 2002;9(Suppl 1):S257-S260.
30. Roberts TP, Helbich TH, Ley S, Turetschek K, Wendland MF, Shames DM, Brasch RC. Utility (or not) of Gd-DTPA-based dynamic MRI for breast cancer diagnosis and grading. Acad Radiol 2002;9(Suppl 1): S261-S265.